ES2192860T3 - Uso de una composicion que comprende heparina como agente de revestimiento superficial no trombogenico para prevenir la trombosis arterial. - Google Patents
Uso de una composicion que comprende heparina como agente de revestimiento superficial no trombogenico para prevenir la trombosis arterial.Info
- Publication number
- ES2192860T3 ES2192860T3 ES99944937T ES99944937T ES2192860T3 ES 2192860 T3 ES2192860 T3 ES 2192860T3 ES 99944937 T ES99944937 T ES 99944937T ES 99944937 T ES99944937 T ES 99944937T ES 2192860 T3 ES2192860 T3 ES 2192860T3
- Authority
- ES
- Spain
- Prior art keywords
- composition
- heparine
- coating agent
- surface coating
- arterial thrombosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 2
- 229920000669 heparin Polymers 0.000 title abstract 2
- 230000001453 nonthrombogenic effect Effects 0.000 title abstract 2
- 206010003178 Arterial thrombosis Diseases 0.000 title 1
- 239000011248 coating agent Substances 0.000 title 1
- 230000008321 arterial blood flow Effects 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Paints Or Removers (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Uso de una composición que comprende heparina enriquecida con respecto a heparina de alta afinidad, HA, acoplada a una superficie, opcionalmente junto con un vehículo conveniente, para preparar una superficie no trombogénica para prevenir la formación de trombosis arterial.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO984144A NO984144L (no) | 1998-09-09 | 1998-09-09 | Sammensetning som omfatter heparin som et ikke-trombogent overflatebelegg |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2192860T3 true ES2192860T3 (es) | 2003-10-16 |
Family
ID=19902394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99944937T Expired - Lifetime ES2192860T3 (es) | 1998-09-09 | 1999-09-09 | Uso de una composicion que comprende heparina como agente de revestimiento superficial no trombogenico para prevenir la trombosis arterial. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6559132B1 (es) |
| EP (1) | EP1112098B1 (es) |
| JP (1) | JP4489297B2 (es) |
| KR (1) | KR100603224B1 (es) |
| AT (1) | ATE232113T1 (es) |
| AU (1) | AU762201B2 (es) |
| BR (1) | BR9913517A (es) |
| CA (1) | CA2342992C (es) |
| DE (1) | DE69905258T2 (es) |
| DK (1) | DK1112098T3 (es) |
| ES (1) | ES2192860T3 (es) |
| NO (1) | NO984144L (es) |
| WO (1) | WO2000013719A1 (es) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6641610B2 (en) | 1998-09-10 | 2003-11-04 | Percardia, Inc. | Valve designs for left ventricular conduits |
| WO2000015147A1 (en) * | 1998-09-10 | 2000-03-23 | Percardia, Inc. | Transmycardial shunt and its attachment mechanism, for left ventricular revascularization |
| US6254564B1 (en) | 1998-09-10 | 2001-07-03 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
| US6290728B1 (en) | 1998-09-10 | 2001-09-18 | Percardia, Inc. | Designs for left ventricular conduit |
| AU6384699A (en) * | 1998-09-10 | 2000-04-03 | Percardia, Inc. | Tmr shunt |
| US6409697B2 (en) | 1999-05-04 | 2002-06-25 | Heartstent Corporation | Transmyocardial implant with forward flow bias |
| US6638237B1 (en) | 1999-08-04 | 2003-10-28 | Percardia, Inc. | Left ventricular conduits and methods for delivery |
| US7033372B1 (en) | 1999-08-04 | 2006-04-25 | Percardia, Inc. | Corkscrew reinforced left ventricle to coronary artery channel |
| JP3782297B2 (ja) * | 2000-03-28 | 2006-06-07 | 株式会社東芝 | 固体撮像装置及びその製造方法 |
| US6854467B2 (en) * | 2000-05-04 | 2005-02-15 | Percardia, Inc. | Methods and devices for delivering a ventricular stent |
| US20020032478A1 (en) * | 2000-08-07 | 2002-03-14 | Percardia, Inc. | Myocardial stents and related methods of providing direct blood flow from a heart chamber to a coronary vessel |
| US6976990B2 (en) | 2001-01-25 | 2005-12-20 | Percardia, Inc. | Intravascular ventriculocoronary bypass via a septal passageway |
| US6783525B2 (en) | 2001-12-12 | 2004-08-31 | Megadyne Medical Products, Inc. | Application and utilization of a water-soluble polymer on a surface |
| US6949118B2 (en) | 2002-01-16 | 2005-09-27 | Percardia, Inc. | Encased implant and methods |
| US7008397B2 (en) | 2002-02-13 | 2006-03-07 | Percardia, Inc. | Cardiac implant and methods |
| US6685704B2 (en) | 2002-02-26 | 2004-02-03 | Megadyne Medical Products, Inc. | Utilization of an active catalyst in a surface coating of an electrosurgical instrument |
| US6619357B1 (en) | 2002-04-24 | 2003-09-16 | The Goodyear Tire & Rubber Company | Belt package for super single truck tires |
| US6951559B1 (en) | 2002-06-21 | 2005-10-04 | Megadyne Medical Products, Inc. | Utilization of a hybrid material in a surface coating of an electrosurgical instrument |
| US7326219B2 (en) * | 2002-09-09 | 2008-02-05 | Wilk Patent Development | Device for placing transmyocardial implant |
| US6702850B1 (en) | 2002-09-30 | 2004-03-09 | Mediplex Corporation Korea | Multi-coated drug-eluting stent for antithrombosis and antirestenosis |
| FR2846520B1 (fr) * | 2002-11-06 | 2006-09-29 | Roquette Freres | Utilisation de maltodextrines branchees comme liants de granulation |
| US7198751B2 (en) * | 2003-01-14 | 2007-04-03 | Medtronic, Inc. | Disposable, integrated, extracorporeal blood circuit |
| US7204958B2 (en) * | 2003-01-14 | 2007-04-17 | Medtronic, Inc. | Extracorporeal blood circuit air removal system and method |
| US7201870B2 (en) * | 2003-01-14 | 2007-04-10 | Medtronic, Inc. | Active air removal system operating modes of an extracorporeal blood circuit |
| US7335334B2 (en) * | 2003-01-14 | 2008-02-26 | Medtronic, Inc. | Active air removal from an extracorporeal blood circuit |
| US7189352B2 (en) * | 2003-01-14 | 2007-03-13 | Medtronic, Inc. | Extracorporeal blood circuit priming system and method |
| US7550443B2 (en) * | 2004-03-26 | 2009-06-23 | Surmodics, Inc. | Process and systems for biocompatible surfaces |
| CA2560507C (en) * | 2004-03-26 | 2011-08-16 | Surmodics, Inc. | Composition and method for preparing biocompatible surfaces |
| US20050281857A1 (en) * | 2004-05-25 | 2005-12-22 | Heyer Toni M | Methods and reagents for preparing biomolecule-containing coatings |
| US20060154894A1 (en) * | 2004-09-15 | 2006-07-13 | Massachusetts Institute Of Technology | Biologically active surfaces and methods of their use |
| US20060159650A1 (en) * | 2005-01-14 | 2006-07-20 | Bacterin, Inc. | Composition and method for covalently coupling an antithrombotic substance and a hydrophilic polymer |
| DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
| US20080200421A1 (en) * | 2007-02-21 | 2008-08-21 | Zhao Jonathon Z | Coating for a medical device having an anti-thrombotic conjugate |
| US20090281059A1 (en) * | 2007-02-21 | 2009-11-12 | Robert Falotico | Coating for a medical device having an anti-thrombotic conjugate |
| US8114465B2 (en) * | 2007-04-02 | 2012-02-14 | Ension, Inc. | Process for preparing a substrate coated with a biomolecule |
| US9693841B2 (en) | 2007-04-02 | 2017-07-04 | Ension, Inc. | Surface treated staples, sutures and dental floss and methods of manufacturing the same |
| US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
| US8383156B2 (en) * | 2007-04-30 | 2013-02-26 | Cordis Corporation | Coating for a medical device having an anti-thrombotic conjugate |
| US20090018646A1 (en) | 2007-07-10 | 2009-01-15 | Zhao Jonathon Z | Coating Employing an Anti-Thrombotic Conjugate |
| US20090036841A1 (en) * | 2007-08-01 | 2009-02-05 | Mckale James M | Coatings for blood and bone marrow-contacting devices |
| US20090192079A1 (en) * | 2007-10-09 | 2009-07-30 | Genzyme Corporation | Prolonged delivery of heparin-binding growth factors from heparin-derivatized collagen |
| US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
| ES2903231T3 (es) | 2008-02-26 | 2022-03-31 | Jenavalve Tech Inc | Stent para el posicionamiento y anclaje de una prótesis valvular en un sitio de implantación en el corazón de un paciente |
| GB0816783D0 (en) * | 2008-09-15 | 2008-10-22 | Carmeda Ab | Immobilised biological entities |
| AU2010215936B2 (en) | 2009-02-21 | 2015-03-05 | Covidien Lp | Medical devices having activated surfaces |
| WO2010095044A2 (en) * | 2009-02-21 | 2010-08-26 | Sofradim Production | Medical device with degradation-retarding coating |
| US20110196478A1 (en) * | 2010-02-10 | 2011-08-11 | Beoptima Inc. | Devices and methods for lumen treatment |
| US10856978B2 (en) | 2010-05-20 | 2020-12-08 | Jenavalve Technology, Inc. | Catheter system |
| JP2013526388A (ja) | 2010-05-25 | 2013-06-24 | イエナバルブ テクノロジー インク | 人工心臓弁、及び人工心臓弁とステントを備える経カテーテル搬送体内プロテーゼ |
| US9180274B2 (en) | 2010-09-09 | 2015-11-10 | W. L. G ore & Associates, Inc | Indwelling luminal devices |
| IT1402059B1 (it) * | 2010-09-29 | 2013-08-28 | Rand Srl | Sistema indossabile per eseguire terapie depurative di fluidi organici con l'impiego di circuiti extracorporei |
| US9775933B2 (en) | 2012-03-02 | 2017-10-03 | W. L. Gore & Associates, Inc. | Biocompatible surfaces and devices incorporating such surfaces |
| JP6432346B2 (ja) | 2013-04-12 | 2018-12-05 | 東レ株式会社 | 抗血栓性を有する人工血管 |
| WO2015028209A1 (en) | 2013-08-30 | 2015-03-05 | Jenavalve Technology Gmbh | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
| US12121461B2 (en) | 2015-03-20 | 2024-10-22 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath |
| WO2016177562A1 (en) | 2015-05-01 | 2016-11-10 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
| EP3095509A1 (en) | 2015-05-18 | 2016-11-23 | Defymed | Membranes functionalized with heparin for bioartificial organs |
| US11065138B2 (en) | 2016-05-13 | 2021-07-20 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
| EP3318294A1 (en) | 2016-11-08 | 2018-05-09 | Defymed | Kit for in situ delivery of a compound of interest |
| US11197754B2 (en) | 2017-01-27 | 2021-12-14 | Jenavalve Technology, Inc. | Heart valve mimicry |
| KR20200037574A (ko) | 2018-10-01 | 2020-04-09 | (주)우리비앤비 | 헤파린을 포함하는 탈모방지용 화장료 조성물 |
| EP3892259A1 (en) | 2020-04-09 | 2021-10-13 | Defymed | Membranes for medical devices |
| CN115697300A (zh) | 2020-04-09 | 2023-02-03 | 帝梵麦德公司 | 用于医疗装置的膜 |
| EP4196788A1 (en) * | 2020-08-14 | 2023-06-21 | Idris Oncology B.V. | A process for applying a coating comprising hyaluronic acid onto the surface of a medical sampling device, and the medical sampling device for capture of circulating tumor cells provided with the coating |
| CN120152682A (zh) | 2022-11-09 | 2025-06-13 | 耶拿阀门科技公司 | 用于顺序地部署可扩张植入物的导管系统 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4446126A (en) * | 1980-09-30 | 1984-05-01 | Cutter Laboratories, Inc. | Antithrombin-heparin complex and method for its production |
| SE456347B (sv) | 1982-02-09 | 1988-09-26 | Ird Biomaterial Ab | Ytmodifierat fast substrat samt forfarande for framstellning derav |
| US6174326B1 (en) * | 1996-09-25 | 2001-01-16 | Terumo Kabushiki Kaisha | Radiopaque, antithrombogenic stent and method for its production |
-
1998
- 1998-09-09 NO NO984144A patent/NO984144L/no not_active Application Discontinuation
-
1999
- 1999-09-09 CA CA2342992A patent/CA2342992C/en not_active Expired - Lifetime
- 1999-09-09 US US09/763,856 patent/US6559132B1/en not_active Expired - Lifetime
- 1999-09-09 BR BR9913517-5A patent/BR9913517A/pt not_active Application Discontinuation
- 1999-09-09 JP JP2000568524A patent/JP4489297B2/ja not_active Expired - Lifetime
- 1999-09-09 DK DK99944937T patent/DK1112098T3/da active
- 1999-09-09 WO PCT/NO1999/000278 patent/WO2000013719A1/en not_active Ceased
- 1999-09-09 EP EP99944937A patent/EP1112098B1/en not_active Expired - Lifetime
- 1999-09-09 DE DE69905258T patent/DE69905258T2/de not_active Expired - Lifetime
- 1999-09-09 KR KR1020017002937A patent/KR100603224B1/ko not_active Expired - Lifetime
- 1999-09-09 ES ES99944937T patent/ES2192860T3/es not_active Expired - Lifetime
- 1999-09-09 AU AU57653/99A patent/AU762201B2/en not_active Expired
- 1999-09-09 AT AT99944937T patent/ATE232113T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| DE69905258T2 (de) | 2003-11-06 |
| NO984144L (no) | 2000-03-10 |
| EP1112098B1 (en) | 2003-02-05 |
| JP4489297B2 (ja) | 2010-06-23 |
| US6559132B1 (en) | 2003-05-06 |
| DE69905258D1 (de) | 2003-03-13 |
| KR100603224B1 (ko) | 2006-07-24 |
| AU5765399A (en) | 2000-03-27 |
| KR20010079758A (ko) | 2001-08-22 |
| ATE232113T1 (de) | 2003-02-15 |
| WO2000013719A1 (en) | 2000-03-16 |
| CA2342992A1 (en) | 2000-03-16 |
| NO984144D0 (no) | 1998-09-09 |
| DK1112098T3 (da) | 2003-05-05 |
| CA2342992C (en) | 2010-11-23 |
| BR9913517A (pt) | 2001-06-05 |
| JP2002524153A (ja) | 2002-08-06 |
| EP1112098A1 (en) | 2001-07-04 |
| AU762201B2 (en) | 2003-06-19 |
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