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ES2186916T3 - Derivados de isoxazolina como agentes antimicrobianos. - Google Patents

Derivados de isoxazolina como agentes antimicrobianos.

Info

Publication number
ES2186916T3
ES2186916T3 ES97937156T ES97937156T ES2186916T3 ES 2186916 T3 ES2186916 T3 ES 2186916T3 ES 97937156 T ES97937156 T ES 97937156T ES 97937156 T ES97937156 T ES 97937156T ES 2186916 T3 ES2186916 T3 ES 2186916T3
Authority
ES
Spain
Prior art keywords
antimicrobial agents
isoxazoline derivatives
isoxazoline
derivatives
national
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97937156T
Other languages
English (en)
Inventor
Michael R Barbachyn
Richard C Thomas
Gary J Cleek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Application granted granted Critical
Publication of ES2186916T3 publication Critical patent/ES2186916T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA COMPUESTOS DE FORMULA (I) O SUS SALES FARMACEUTICAMENTE ACEPTABLES, CARACTERIZADOS PORQUE A Y R 1 SON TAL COMO SE DEFINEN EN LAS REIVINDICACIO NES, Y SON AGENTES ANTIBACTERIANOS.
ES97937156T 1996-08-21 1997-08-15 Derivados de isoxazolina como agentes antimicrobianos. Expired - Lifetime ES2186916T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2428796P 1996-08-21 1996-08-21

Publications (1)

Publication Number Publication Date
ES2186916T3 true ES2186916T3 (es) 2003-05-16

Family

ID=21819822

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97937156T Expired - Lifetime ES2186916T3 (es) 1996-08-21 1997-08-15 Derivados de isoxazolina como agentes antimicrobianos.

Country Status (10)

Country Link
US (2) US5990136A (es)
EP (1) EP0920421B1 (es)
JP (1) JP2000516245A (es)
AT (1) ATE227277T1 (es)
AU (1) AU3973697A (es)
DE (1) DE69716925T2 (es)
DK (1) DK0920421T3 (es)
ES (1) ES2186916T3 (es)
PT (1) PT920421E (es)
WO (1) WO1998007708A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
CN1138765C (zh) * 1997-05-30 2004-02-18 法玛西雅厄普约翰美国公司 带有硫代羰基功能基的噁唑烷酮抗菌剂
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
ES2182485T3 (es) * 1998-02-13 2003-03-01 Upjohn Co Derivados de aminofenil isosazolina sustituidos utiles como agentes antimicrobianos.
JP2002504550A (ja) * 1998-02-25 2002-02-12 ファルマシア・アンド・アップジョン・カンパニー 抗微生物剤として有用な置換アミノメチルイソオキサゾリン誘導体
IL140084A0 (en) 1998-06-05 2002-02-10 Astra Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
TW572757B (en) * 1998-08-24 2004-01-21 Bristol Myers Squibb Co Novel isoxazolinone antibacterial agents
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
GB9928568D0 (en) * 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
US6689769B2 (en) 2000-12-21 2004-02-10 Pharmacia & Upjohn Company Antimicrobial quinolone derivatives and use of the same to treat bacterial infections
AU2002222682B8 (en) * 2000-12-26 2008-05-29 Research Foundation Itsuu Laboratory Tropolone Derivatives
JP2005512975A (ja) * 2001-10-25 2005-05-12 アストラゼネカ アクチボラグ 抗菌薬として有用なイソキサゾリン誘導体
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
EP1594865A2 (en) * 2003-02-07 2005-11-16 Warner-Lambert Company LLC Antibacterial agents
MXPA05007937A (es) * 2003-02-07 2005-09-30 Warner Lambert Co Agentes antibacterianos.
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
MX2007001568A (es) * 2004-08-06 2007-04-16 Pharmacia & Upjohn Co Llc Oxindol oxazolidinonas como agentes antibacterianos.
MX2007002929A (es) * 2004-09-10 2007-08-16 Syngenta Ltd Isoxazoles sustituidos como funguicidas.
CA2807005C (en) * 2010-08-05 2015-04-07 Ah Usa 42 Llc Isoxazoline derivatives as antiparasitic agents
US9173887B2 (en) 2010-12-22 2015-11-03 Abbvie Inc. Hepatitis C inhibitors and uses thereof
GB2521558B (en) * 2012-10-03 2019-03-27 Shell Int Research Optimizing performance of a drilling assembly
WO2021000297A1 (en) 2019-07-03 2021-01-07 Merck Sharp & Dohme Corp. Compounds and methods of use thereof as antibacterial agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137326C (es) * 1967-08-26
US4283403A (en) * 1976-06-14 1981-08-11 Eli Lilly And Company Substituted isoxazolines for control of plant phytopathogens
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
EP0673370B1 (en) * 1992-12-08 1998-01-07 PHARMACIA & UPJOHN COMPANY Tropone-substituted phenyloxazolidinone antibacterial agents
PT730587E (pt) * 1993-11-26 2000-05-31 Pfizer 3-aril-2-isoxazolinas como agentes anti-inflamatorios
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
US5710159A (en) * 1996-05-09 1998-01-20 The Dupont Merck Pharmaceutical Company Integrin receptor antagonists

Also Published As

Publication number Publication date
US5990136A (en) 1999-11-23
DE69716925D1 (de) 2002-12-12
JP2000516245A (ja) 2000-12-05
DK0920421T3 (da) 2003-03-10
US6093736A (en) 2000-07-25
AU3973697A (en) 1998-03-06
DE69716925T2 (de) 2003-09-11
EP0920421A1 (en) 1999-06-09
PT920421E (pt) 2003-03-31
ATE227277T1 (de) 2002-11-15
EP0920421B1 (en) 2002-11-06
WO1998007708A1 (en) 1998-02-26

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