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ES2186427T3 - Clonacion y copia sobre superficies. - Google Patents

Clonacion y copia sobre superficies.

Info

Publication number
ES2186427T3
ES2186427T3 ES99962118T ES99962118T ES2186427T3 ES 2186427 T3 ES2186427 T3 ES 2186427T3 ES 99962118 T ES99962118 T ES 99962118T ES 99962118 T ES99962118 T ES 99962118T ES 2186427 T3 ES2186427 T3 ES 2186427T3
Authority
ES
Spain
Prior art keywords
immobilization
ligand
transmission
ligands
receiver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99962118T
Other languages
English (en)
Inventor
Kiedrowski Gunter Von
Jens Peter Furste
Sven Klussmann
Thomas Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TME Pharma AG
Original Assignee
Noxxon Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noxxon Pharma AG filed Critical Noxxon Pharma AG
Application granted granted Critical
Publication of ES2186427T3 publication Critical patent/ES2186427T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Laminated Bodies (AREA)
  • Absorbent Articles And Supports Therefor (AREA)

Abstract

Procedimiento para la multiplicación de ligandos y receptores en dos superficies como mínimo, abarcando uno o más de los siguientes ciclos: a) Inmovilización de un ligando en una prime ra superficie de una fase sólida; b) Adición de una solución de receptores y li gazón de los receptores complementarios a los ligandos; c) Transmisión del receptor a otra superficie e inmovilización en dicha superficie del receptor; d) Adherencia de otro ligando al receptor in movilizado; e) Transmisión del ligando a otra superficie cualquiera e inmovilización del mismo en di cha superficie; produciéndose la transmisión en los pasos (c) y (e) al activar un campo eléctrico entre la primera y la segunda superficie.
ES99962118T 1998-11-27 1999-11-26 Clonacion y copia sobre superficies. Expired - Lifetime ES2186427T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19854946A DE19854946C2 (de) 1998-11-27 1998-11-27 Klonieren und Kopieren an Oberflächen

Publications (1)

Publication Number Publication Date
ES2186427T3 true ES2186427T3 (es) 2003-05-01

Family

ID=7889332

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99962118T Expired - Lifetime ES2186427T3 (es) 1998-11-27 1999-11-26 Clonacion y copia sobre superficies.

Country Status (8)

Country Link
US (1) US6534271B2 (es)
EP (1) EP1135527B1 (es)
JP (1) JP2002531098A (es)
AT (1) ATE226258T1 (es)
AU (1) AU1857300A (es)
DE (3) DE19854946C2 (es)
ES (1) ES2186427T3 (es)
WO (1) WO2000032809A2 (es)

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SE0002700D0 (sv) * 2000-07-18 2000-07-18 Karolinska Innovations Ab Method of preparing nucleic acid microchips
DE10046069A1 (de) * 2000-09-15 2002-04-04 Hubert S Bernauer Mikro-Polynucleotidsynthese
DE10106320A1 (de) * 2001-02-09 2002-08-22 Axaron Bioscience Ag Erzeugung und Verwendung von Zufallsanordnungen klonaler Nukleinsäureinseln auf einer Oberfläche
WO2003022480A1 (en) * 2001-09-11 2003-03-20 Emerson Electric Co. Crimping assembly
US7563600B2 (en) 2002-09-12 2009-07-21 Combimatrix Corporation Microarray synthesis and assembly of gene-length polynucleotides
US7459316B2 (en) 2003-02-24 2008-12-02 National Research Council Of Canada Molecularly-imprinted chemical detection device and method
US7558575B2 (en) 2003-07-24 2009-07-07 Motorola Inc. Method and apparatus for wireless communication in a high velocity environment
WO2006002934A1 (en) * 2004-06-30 2006-01-12 Rina Netzwerk Rna Technologien Gmbh Blueprint biochips
JP4954196B2 (ja) * 2005-04-12 2012-06-13 マサチューセッツ インスティテュート オブ テクノロジー ナノコンタクト・プリント
WO2007136834A2 (en) * 2006-05-19 2007-11-29 Codon Devices, Inc. Combined extension and ligation for nucleic acid assembly
WO2008027558A2 (en) 2006-08-31 2008-03-06 Codon Devices, Inc. Iterative nucleic acid assembly using activation of vector-encoded traits
EP2407558A1 (en) 2006-10-31 2012-01-18 Noxxon Pharma AG Methods for the detection of a single- or double-stranded nucleic acid molecule
WO2011056872A2 (en) 2009-11-03 2011-05-12 Gen9, Inc. Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly
WO2011066185A1 (en) 2009-11-25 2011-06-03 Gen9, Inc. Microfluidic devices and methods for gene synthesis
US9217144B2 (en) 2010-01-07 2015-12-22 Gen9, Inc. Assembly of high fidelity polynucleotides
AU2011338841B2 (en) 2010-11-12 2017-02-16 Gen9, Inc. Methods and devices for nucleic acids synthesis
EP2637780B1 (en) 2010-11-12 2022-02-09 Gen9, Inc. Protein arrays and methods of using and making the same
DE102011010307A1 (de) * 2011-02-03 2012-08-09 Albert-Ludwigs-Universität Freiburg Vorrichtung und Verfahren zur Erzeugung von Protein-Mikroarrays
AU2012300401B2 (en) 2011-08-26 2018-02-08 Ginkgo Bioworks, Inc. Compositions and methods for high fidelity assembly of nucleic acids
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
EP2841601B1 (en) 2012-04-24 2019-03-06 Gen9, Inc. Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
US20150191719A1 (en) 2012-06-25 2015-07-09 Gen9, Inc. Methods for Nucleic Acid Assembly and High Throughput Sequencing

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
DE6940964U (de) * 1969-10-21 1970-02-12 Georg Schatz Lederwarenfabrik Mal- und basteletui
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
CA2004326A1 (en) * 1988-12-23 1990-06-23 Nanibushan Dattagupta Assay of sequences using amplified genes
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US6017696A (en) * 1993-11-01 2000-01-25 Nanogen, Inc. Methods for electronic stringency control for molecular biological analysis and diagnostics
WO1993017126A1 (en) * 1992-02-19 1993-09-02 The Public Health Research Institute Of The City Of New York, Inc. Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
US5795714A (en) * 1992-11-06 1998-08-18 Trustees Of Boston University Method for replicating an array of nucleic acid probes
KR960703174A (ko) * 1993-06-09 1996-06-19 미안 알렉 자기장 순환식 반응방법(magnetic cycle reaction)
US5641658A (en) 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
AU6752496A (en) * 1995-07-28 1997-03-05 Ely Michael Rabani Pattern formation, replication, fabrication and devices thereby
US5660990A (en) * 1995-08-18 1997-08-26 Immunivest Corporation Surface immobilization of magnetically collected materials
US6013440A (en) * 1996-03-11 2000-01-11 Affymetrix, Inc. Nucleic acid affinity columns
JP3377215B2 (ja) * 1996-09-06 2003-02-17 インターナショナル・ビジネス・マシーンズ・コーポレーション 化学的に定義されたボディを配向析出する方法
US6124092A (en) * 1996-10-04 2000-09-26 The Perkin-Elmer Corporation Multiplex polynucleotide capture methods and compositions
DE19782097T1 (de) * 1996-11-06 1999-10-14 Sequenom Inc Zusammensetzungen und Verfahren zur Immobilisierung von Nucleinsäuren an feste Träger
WO1999019341A1 (en) * 1997-10-10 1999-04-22 President & Fellows Of Harvard College Replica amplification of nucleic acid arrays
WO2000027521A1 (en) * 1998-11-06 2000-05-18 Solexa Ltd. A method for reproducing molecular arrays

Also Published As

Publication number Publication date
DE19854946C2 (de) 2002-01-03
JP2002531098A (ja) 2002-09-24
US6534271B2 (en) 2003-03-18
DE59903121D1 (de) 2002-11-21
EP1135527B1 (de) 2002-10-16
EP1135527A2 (de) 2001-09-26
DE19854946A1 (de) 2000-06-08
WO2000032809A3 (de) 2000-10-19
US20020022275A1 (en) 2002-02-21
ATE226258T1 (de) 2002-11-15
WO2000032809A2 (de) 2000-06-08
DE19982556D2 (de) 2002-01-24
AU1857300A (en) 2000-06-19

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