[go: up one dir, main page]

ES2185395T3 - Composiciones mucoadhesivas liquidas orales. - Google Patents

Composiciones mucoadhesivas liquidas orales.

Info

Publication number
ES2185395T3
ES2185395T3 ES99942428T ES99942428T ES2185395T3 ES 2185395 T3 ES2185395 T3 ES 2185395T3 ES 99942428 T ES99942428 T ES 99942428T ES 99942428 T ES99942428 T ES 99942428T ES 2185395 T3 ES2185395 T3 ES 2185395T3
Authority
ES
Spain
Prior art keywords
agents
composition
oral
oral liquid
mucoadhesive compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99942428T
Other languages
English (en)
Inventor
Douglas Joseph Dobrozsi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of ES2185395T3 publication Critical patent/ES2185395T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Anesthesiology (AREA)
  • Physiology (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

Una composición farmacéutica líquida acuosa, mucorretentiva per oral, oral o intranasal, que comprende: a) de 2% a 50% en peso de la composición, de partículas coloidales de sílice; y b) una cantidad segura y eficaz de un principio activo farmacéutico seleccionado del grupo formado por: agentes gastrointestinales, analgésicos, descongestionantes, expectorantes, antitusígenos, antihistamínicos, broncodilatadores, anestésicos tópicos, agentes sensoriales, agentes del cuidado bucal, agentes respiratorios varios y mezclas de éstos; en la que la composición presenta una razón volumétrica de sedimentación mayor que 0,90 cuando se mide al cabo de 48
ES99942428T 1998-08-24 1999-08-24 Composiciones mucoadhesivas liquidas orales. Expired - Lifetime ES2185395T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9764698P 1998-08-24 1998-08-24

Publications (1)

Publication Number Publication Date
ES2185395T3 true ES2185395T3 (es) 2003-04-16

Family

ID=22264456

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99942428T Expired - Lifetime ES2185395T3 (es) 1998-08-24 1999-08-24 Composiciones mucoadhesivas liquidas orales.

Country Status (18)

Country Link
US (2) US20020009478A1 (es)
EP (1) EP1107732B1 (es)
JP (1) JP2002523353A (es)
KR (1) KR20010074834A (es)
CN (1) CN1313754A (es)
AT (1) ATE227978T1 (es)
AU (1) AU753251B2 (es)
BR (1) BR9913148A (es)
CA (1) CA2338480C (es)
CO (1) CO5140074A1 (es)
DE (1) DE69904057T2 (es)
DK (1) DK1107732T3 (es)
ES (1) ES2185395T3 (es)
HU (1) HUP0103217A2 (es)
NO (1) NO20010830D0 (es)
PE (1) PE20000863A1 (es)
TR (1) TR200100569T2 (es)
WO (1) WO2000010528A1 (es)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020009478A1 (en) * 1998-08-24 2002-01-24 Douglas Joseph Dobrozsi Oral liquid mucoadhesive compositions
EP1363600B1 (en) * 2001-02-15 2008-10-01 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
US7544348B2 (en) * 2001-02-15 2009-06-09 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
ES2195757B1 (es) * 2001-12-28 2005-03-01 Laboratorios Calier, S.A. Procedimiento para combatir las infestaciones de las colmenas de abejas.
AU2003222990B2 (en) * 2002-05-02 2009-11-12 Cragmont Pharmaceuticals, Llc Therapeutic 1,2,3,6-tetrahydropyrimidine-2-one compositions and methods therewith
LT1531794T (lt) * 2002-06-28 2017-08-25 Civitas Therapeutics, Inc. Inhaliuojamas epinefrinas
US6669929B1 (en) 2002-12-30 2003-12-30 Colgate Palmolive Company Dentifrice containing functional film flakes
US20050058672A1 (en) * 2003-09-14 2005-03-17 Bioderm Research Baby Care Skin Protectant Compositions for Diaper Rash
DE10332486A1 (de) * 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung akuter Schmerzen
US7482378B2 (en) * 2004-05-28 2009-01-27 Millenium Specialty Chemicals, Inc. Physiological cooling compositions
US7906140B2 (en) * 2004-06-17 2011-03-15 Virun, Inc. Compositions for mucosal delivery of agents
LT2522365T (lt) 2004-11-24 2017-02-10 Meda Pharmaceuticals Inc. Kompozicijos, apimančios azelastiną, ir jų panaudojimo būdai
US20060216359A1 (en) * 2005-03-25 2006-09-28 Lowell Riegel Topical preparation for treating ulcerations on the inside of the month
TR200803299T1 (tr) * 2005-11-10 2008-11-21 Century Biologicals Private Limited Solunum yolu rahatsızlıklarını tedavi etmek için kullanılan dengeli bir formülasyon.
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
FR2900824A1 (fr) * 2006-05-10 2007-11-16 Prod Dentaires Pierre Rolland Pate destinee a arreter les saignements, ses utilisations, et seringue la contenant
US7803778B2 (en) 2006-05-23 2010-09-28 Theracos, Inc. Glucose transport inhibitors and methods of use
US8748419B2 (en) 2006-06-16 2014-06-10 Theracos, Inc. Treating obesity with muscarinic receptor M1 antagonists
US7893053B2 (en) 2006-06-16 2011-02-22 Theracos, Inc. Treating psychological conditions using muscarinic receptor M1 antagonists
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs
CN101138541B (zh) * 2006-09-06 2010-10-06 上海医药工业研究院 氨来占诺局部成膜凝胶组合物及其应用
AU2008232419B2 (en) 2007-04-02 2013-06-20 Theracos, Inc. Benzylic glycoside derivatives and methods of use
UA99924C2 (en) 2007-08-23 2012-10-25 Теракос, Инк. Benzylbenzol derivatives and using thereof
US20090123570A1 (en) * 2007-11-09 2009-05-14 Warner W Randolph Composition and method for treating sore throat
US20090123390A1 (en) 2007-11-13 2009-05-14 Meritage Pharma, Inc. Compositions for the treatment of gastrointestinal inflammation
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
CA2705681C (en) 2007-11-13 2013-06-18 Meritage Pharma, Inc. Corticosteroid compositions
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20090148530A1 (en) 2007-12-08 2009-06-11 Jamie Koufman Method for prevention and treatment of reflux injury in the aerodigestive tract and laryngopharynx caused by pepsin
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
BRPI0910850B1 (pt) 2008-04-21 2022-06-14 Otonomy, Inc. Composição intratimpânica compreendendo fator neurotrófico de crescimento derivado do cérebro (bdnf) para o tratamento ou prevenção da perda auditiva
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
TWI523652B (zh) 2008-07-15 2016-03-01 泰瑞克公司 氘化苄基苯衍生物及使用方法
US8784870B2 (en) 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
WO2010011605A2 (en) 2008-07-21 2010-01-28 Otonomy, Inc. Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders
WO2010021636A1 (en) 2008-08-20 2010-02-25 The Regents Of The University Of California Corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
SMT201600475T1 (it) 2008-08-22 2017-03-08 Theracos Sub Llc Procedimenti per la preparazione di inibitori di sglt2.
US7914828B2 (en) * 2008-10-17 2011-03-29 Levine Brian M Combination herbal product to benefit respiratory tract
ES2554375T3 (es) 2008-11-25 2015-12-18 University Of Rochester Inhibidores de las MLK y métodos de uso
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy
NZ603644A (en) 2010-05-24 2014-10-31 Univ Rochester Bicyclic heteroaryl kinase inhibitors and methods of use
WO2011153712A1 (en) 2010-06-12 2011-12-15 Theracos, Inc. Crystalline form of benzylbenzene sglt2 inhibitor
US8361519B2 (en) 2010-11-18 2013-01-29 Aadvantics Pharmaceuticals, Inc. Combination herbal product to benefit respiratory tract in people exposed to smoke
WO2012112933A1 (en) 2011-02-18 2012-08-23 The Scripps Research Institute Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
US8524664B2 (en) 2011-06-02 2013-09-03 Colorado Seminary, Which owns and Operates The Univeristy of Denver Methods of treating overproduction of cortisol using ACTH antagonist peptides
BR112014021218A2 (pt) 2012-02-27 2020-10-27 Bayer New Zealand Limited composições de liberação controlada e seus métodos de uso
US20150133565A1 (en) * 2012-06-15 2015-05-14 University Of New Hampshire Sustained release hydrogel-based stimulant
US9636360B2 (en) * 2012-09-18 2017-05-02 pH Science Holdings, Inc Method and composition for treating gastro-esophageal disorders
EP2925319B1 (en) 2012-11-30 2019-01-09 University Of Rochester Mixed lineage kinase inhibitors for hiv/aids therapies
US11135158B2 (en) 2014-05-26 2021-10-05 Michael Lee Martin Medicated hard candy product for treating esophageal inflammation and a method using the same
CA2980165C (en) * 2015-03-26 2021-06-15 Patheon Softgels Inc. Liquisoft capsules
CN108699160A (zh) 2015-07-28 2018-10-23 奥德纳米有限公司 用于治疗耳部病况的TrkB或TrkC激动剂组合物和方法
PL3355862T3 (pl) * 2015-09-28 2020-11-30 Evonik Operations Gmbh Doustne kompozycje przeciwdrobnoustrojowe na bazie krzemionki
CA3029281A1 (en) 2016-06-29 2018-01-04 Otonomy, Inc. Triglyceride otic formulations and uses thereof
IL275780B2 (en) 2018-01-09 2024-07-01 Otonomy Inc Growth factor otic formulations
WO2019154895A1 (en) 2018-02-08 2019-08-15 Strekin Ag Gel formulation for preventing or treating hearing loss
CN113453664A (zh) * 2019-03-14 2021-09-28 因特蒙特技术股份有限公司 用于预防通过口腔和咽部获得的疾病的制剂
JP2023539940A (ja) 2020-09-08 2023-09-20 アルタミラ メディカ， アーゲー 感染を防止するための組成物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3352752A (en) * 1963-07-25 1967-11-14 Tintex Corp Intestinal adsorbent compositions
US4042679A (en) * 1975-11-07 1977-08-16 Colgate-Palmolive Company Antibacterial oral composition
ZA831186B (en) * 1982-03-22 1983-11-30 Upjohn Ltd Gelled pge2/triacetin solutions
US4427681A (en) * 1982-09-16 1984-01-24 Richardson-Vicks, Inc. Thixotropic compositions easily convertible to pourable liquids
NL193682C (nl) * 1987-05-14 2000-07-04 Glaxo Group Ltd Beklede cefuroximaxetilsamenstelling.
US5047244A (en) * 1988-06-03 1991-09-10 Watson Laboratories, Inc. Mucoadhesive carrier for delivery of therapeutical agent
US4980175A (en) * 1989-01-03 1990-12-25 Leonard Chavkin Liquid orally administrable compositions based on edible oils
US4988679A (en) * 1989-01-03 1991-01-29 Leonard Chavkin Liquid sustained release composition
US5112604A (en) * 1989-09-01 1992-05-12 Riker Laboratories, Inc. Oral suspension formulation
FI913127A7 (fi) * 1989-10-31 1991-06-27 Watson Laboratories Limakalvoon tarttuva tukisysteemi terapeuttisen aineen vapauttamista v arten
JPH0639368B2 (ja) * 1990-02-28 1994-05-25 株式会社萩原技研 シリカゲルを母体とした抗菌性組生物
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
WO1996021432A1 (en) * 1995-01-11 1996-07-18 Cygnus, Inc. Delivery of active substances by way of mucosal surfaces of pharyngeal and esophageal regions
IT1275955B1 (it) * 1995-03-22 1997-10-24 Dompe Spa Formulazioni farmaceutiche in forma di gel tissotropico
US5589160A (en) * 1995-05-02 1996-12-31 The Procter & Gamble Company Dentifrice compositions
US5658553A (en) * 1995-05-02 1997-08-19 The Procter & Gamble Company Dentifrice compositions
US6184220B1 (en) * 1998-03-27 2001-02-06 Boehringer Ingelheim Pharma Kg Oral suspension of pharmaceutical substance
US20020009478A1 (en) * 1998-08-24 2002-01-24 Douglas Joseph Dobrozsi Oral liquid mucoadhesive compositions

Also Published As

Publication number Publication date
CA2338480A1 (en) 2000-03-02
BR9913148A (pt) 2001-09-25
US6638521B2 (en) 2003-10-28
AU5580899A (en) 2000-03-14
US20020076421A1 (en) 2002-06-20
KR20010074834A (ko) 2001-08-09
CO5140074A1 (es) 2002-03-22
ATE227978T1 (de) 2002-12-15
EP1107732B1 (en) 2002-11-20
EP1107732A1 (en) 2001-06-20
DK1107732T3 (da) 2003-03-17
WO2000010528A1 (en) 2000-03-02
JP2002523353A (ja) 2002-07-30
PE20000863A1 (es) 2000-09-12
NO20010830L (no) 2001-02-19
DE69904057T2 (de) 2003-08-21
DE69904057D1 (de) 2003-01-02
TR200100569T2 (tr) 2001-07-23
US20020009478A1 (en) 2002-01-24
CN1313754A (zh) 2001-09-19
CA2338480C (en) 2004-10-05
NO20010830D0 (no) 2001-02-19
HUP0103217A2 (hu) 2001-12-28
AU753251B2 (en) 2002-10-10

Similar Documents

Publication Publication Date Title
ES2185395T3 (es) Composiciones mucoadhesivas liquidas orales.
ATE300282T1 (de) Orale flüssige mucoadhäsive zusammensetzungen
RU2697881C2 (ru) Стабилизация пленки оксида цинка в композициях для ухода за полостью рта
ES2385236B2 (es) Composición y método para reducir la desmineralización de los dientes.
CA2504489A1 (en) Chewable solid unit dosage forms and methods for delivery of active agents into occlusal surfaces of teeth
HRP20030951B1 (hr) Formulacije jednodnevnih doza oksikodona
CN104921966A (zh) 口腔护理产品及其使用和生产方法
ATE345782T1 (de) Dosierungsformen enthaltend geschmacksmaskierten wirkstoffen
PE20020237A1 (es) Composicion oral topica
IL186655A0 (en) Mucoadhesive xyloglucan-containing formulations useful in medical devices and in pharmaceutical formulations
TW200934480A (en) Novel salts and their uses
BR0213930A (pt) Composições orais sólidas antitártaro e antiplaca
NO983608L (no) Anti-stein munnpleiemiddel inneholdende höy-löselig pyrofosfat
ES2171440T3 (es) Composicion solida mucoadhesiva, terapeutica o higienica, para administracion por aplicacion sobre la mucosa bucal o nasal.
ES2182562T3 (es) Composiciones mucoadhesivas liquidas orales.
BR0007473A (pt) Composições tendo estabilidade melhorada
FR2826868B1 (fr) Composition pour l'hygiene bucco-dentaire comprenant un vecteur d'ions fluorure et un agent antioxydant, ses utilisations notamment pour l'hygiene bucco-dentaire des sujets diabetiques
JP2020531499A5 (es)
IT202000017239A1 (it) Nuova modalità d’uso di prodotti chimici in libero commercio per la formazione nelle mucose orali e nelle prime vie aeree, una barriera biocida di protezione individuale contro il contagio da coronavirus (covid 19)