ES2182137T3 - Empleo de mezclas de productos activos, que contienen fitoestenoles y/o esteres de fitoestenol y agentes potenciadores para la obtencion de agentes hipocolesterinemicos. - Google Patents
Empleo de mezclas de productos activos, que contienen fitoestenoles y/o esteres de fitoestenol y agentes potenciadores para la obtencion de agentes hipocolesterinemicos.Info
- Publication number
- ES2182137T3 ES2182137T3 ES97951916T ES97951916T ES2182137T3 ES 2182137 T3 ES2182137 T3 ES 2182137T3 ES 97951916 T ES97951916 T ES 97951916T ES 97951916 T ES97951916 T ES 97951916T ES 2182137 T3 ES2182137 T3 ES 2182137T3
- Authority
- ES
- Spain
- Prior art keywords
- agents
- esteres
- mixtures
- phytesthenols
- phytesthenol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000003389 potentiating effect Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 239000001828 Gelatine Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
- A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
PARA FABRICAR AGENTES HIPOCOLESTEROLEMICOS SE PROPONE LA UTILIZACION DE MEZCLAS DE PRINCIPIOS ACTIVOS, QUE CONTIENEN (A) FITOSTENOLES Y/O ESTERES DE FITOSTENOL, Y (B) AGENTES DE POTENCIACION, ELEGIDOS DEL GRUPO FORMADO POR QUITOSANOS, SULFATOS DE FITOSTENOL Y/O ACIDOS (DESOXI)RIBONUCLEICOS. AUNQUE LOS AGENTES DE POTENCIACION MISMOS NO POSEEN NADA DE O SOLO UN POQUITO DE ACCION HIPOCOLESTEROLEMICA, ELEVAN LA VELOCIDAD CON LA CUAL LOS ESTERES DE FITOSTENOL BAJAN EL CONTENIDO EN COLESTEROL EN EL SUERO. SI SE ENCAPSULAN EN GELATINA SE PUEDEN TOMAR LOS AGENTES SIN PROBLEMA TAMBIEN POR VIA ORAL EN DOSIS ELEVADAS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19649286 | 1996-11-28 | ||
| DE19700796A DE19700796C2 (de) | 1996-11-28 | 1997-01-13 | Wirkstoffmischungen zur Verminderung des Cholesteringehaltes im Serum von Warmblütern |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2182137T3 true ES2182137T3 (es) | 2003-03-01 |
Family
ID=26031678
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97950201T Expired - Lifetime ES2176805T3 (es) | 1996-11-28 | 1997-11-19 | Empleo de mezclas de productos activos para la obtencion de agentes hipocolesterinemicos. |
| ES97951916T Expired - Lifetime ES2182137T3 (es) | 1996-11-28 | 1997-11-19 | Empleo de mezclas de productos activos, que contienen fitoestenoles y/o esteres de fitoestenol y agentes potenciadores para la obtencion de agentes hipocolesterinemicos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97950201T Expired - Lifetime ES2176805T3 (es) | 1996-11-28 | 1997-11-19 | Empleo de mezclas de productos activos para la obtencion de agentes hipocolesterinemicos. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6383514B1 (es) |
| EP (2) | EP0941097B1 (es) |
| JP (2) | JP2001508046A (es) |
| AU (2) | AU713665B2 (es) |
| CA (2) | CA2273341A1 (es) |
| DK (2) | DK0941097T3 (es) |
| ES (2) | ES2176805T3 (es) |
| NO (2) | NO992564L (es) |
| NZ (1) | NZ335990A (es) |
| WO (2) | WO1998023277A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU664827B2 (en) * | 1991-05-03 | 1995-12-07 | Raisio Benecol Ltd. | A substance for lowering high cholesterol level in serum and a method for preparing the same |
| DE19750422C1 (de) * | 1997-11-14 | 1998-11-26 | Henkel Kgaa | Verwendung von ausgewählten Phytostenolestern zur Herstellung von hypocholesterinämischen Mitteln |
| US6242001B1 (en) * | 1998-11-30 | 2001-06-05 | Mcneil-Ppc, Inc. | Method for producing dispersible sterol and stanol compounds |
| ATE258417T1 (de) * | 1999-07-02 | 2004-02-15 | Cognis Iberia Sl | Mikrokapseln - i |
| US6677327B1 (en) | 1999-11-24 | 2004-01-13 | Archer-Daniels-Midland Company | Phytosterol and phytostanol compositions |
| GB0513881D0 (en) * | 2005-07-06 | 2005-08-10 | Btg Int Ltd | Core 2 GLCNAC-T Inhibitors III |
| US20080182801A1 (en) * | 2003-12-22 | 2008-07-31 | Btg International Limited | Core 2 glcnac-t inhibitors |
| GB0329667D0 (en) * | 2003-12-22 | 2004-01-28 | King S College London | Core 2 GlcNAc-T inhibitor |
| EP1600062A1 (en) * | 2004-05-25 | 2005-11-30 | Cognis IP Management GmbH | Oral and/or topical compositions comprising prebiotics and sterols |
| GB0512726D0 (en) * | 2005-06-22 | 2005-07-27 | Btg Int Ltd | Multiple sclerosis therapy and diagnosis |
| GB0513888D0 (en) | 2005-07-06 | 2005-08-10 | Btg Int Ltd | Core 2 GLCNAC-T Inhibitors II |
| GB0513883D0 (en) * | 2005-07-06 | 2005-08-10 | Btg Int Ltd | Diagnosis of Atherosclerosis |
| US9637515B2 (en) * | 2006-11-06 | 2017-05-02 | Jina Pharmaceuticals, Inc. | Guggulphospholipid methods and compositions |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3085939A (en) | 1959-05-11 | 1963-04-16 | Upjohn Co | Oil-in-water emulsion for oral administration, and process for preparation |
| US3203862A (en) | 1960-03-11 | 1965-08-31 | Jones John Harris | Oral anti-hypercholesterol composition |
| US3089939A (en) | 1960-04-06 | 1963-05-14 | Kamborian | Dip-type adhesive container |
| CA928140A (en) | 1969-07-17 | 1973-06-12 | A. Erickson Billy | Clear cooking and salad oils having hypocholesterolemic properties |
| JPS57206336A (en) | 1981-06-12 | 1982-12-17 | Ajinomoto Co Inc | Edible oil |
| CA1185500A (en) | 1981-08-12 | 1985-04-16 | Joseph Z. Zdrok | Disposable respirator |
| DE3672270D1 (de) | 1985-03-06 | 1990-08-02 | Yoshikawa Oil & Fat | Verfahren zur herstellung von fettsaeureestern. |
| JPS62186936A (ja) | 1986-02-13 | 1987-08-15 | Asahi Denka Kogyo Kk | ステリン乳化乃至可溶化組成物 |
| FR2620024B1 (fr) | 1987-09-09 | 1991-03-15 | Dermatologiques Et | Composition cosmetique comportant un agent antiradicaux libres, et agent correspondant |
| US5362732A (en) * | 1989-12-20 | 1994-11-08 | University Of North Carolina At Chapel Hill | Boronated compounds |
| AU664827B2 (en) | 1991-05-03 | 1995-12-07 | Raisio Benecol Ltd. | A substance for lowering high cholesterol level in serum and a method for preparing the same |
| US5352458A (en) | 1992-12-21 | 1994-10-04 | Applied Genetics Inc. | Tanning method using DNA repair liposomes |
| KR970008132B1 (ko) | 1993-02-08 | 1997-05-21 | 전동원 | 생체 임상의학용 키틴 및 키토산 제조방법 |
| US5470577A (en) | 1993-07-07 | 1995-11-28 | Trustees Of Boston University | Stimulation of tanning by DNA fragments or single-stranded DNA |
| DE4323615A1 (de) | 1993-07-12 | 1995-01-19 | Schreiner Edelgard | Mittel gegen vorzeitiges Altern der Haut |
| DE4442987C2 (de) | 1994-12-02 | 1997-04-17 | Henkel Kgaa | Kationische Chitinabbauprodukte |
-
1997
- 1997-11-19 EP EP97950201A patent/EP0941097B1/de not_active Revoked
- 1997-11-19 CA CA002273341A patent/CA2273341A1/en not_active Withdrawn
- 1997-11-19 WO PCT/EP1997/006450 patent/WO1998023277A1/de not_active Ceased
- 1997-11-19 AU AU53229/98A patent/AU713665B2/en not_active Ceased
- 1997-11-19 CA CA002272754A patent/CA2272754A1/en not_active Abandoned
- 1997-11-19 AU AU55531/98A patent/AU714993B2/en not_active Ceased
- 1997-11-19 NZ NZ335990A patent/NZ335990A/xx unknown
- 1997-11-19 WO PCT/EP1997/006447 patent/WO1998023275A1/de not_active Ceased
- 1997-11-19 DK DK97950201T patent/DK0941097T3/da active
- 1997-11-19 JP JP52424098A patent/JP2001508046A/ja not_active Withdrawn
- 1997-11-19 EP EP97951916A patent/EP0952837B1/de not_active Expired - Lifetime
- 1997-11-19 DK DK97951916T patent/DK0952837T3/da active
- 1997-11-19 ES ES97950201T patent/ES2176805T3/es not_active Expired - Lifetime
- 1997-11-19 ES ES97951916T patent/ES2182137T3/es not_active Expired - Lifetime
- 1997-11-19 US US09/308,512 patent/US6383514B1/en not_active Expired - Fee Related
- 1997-11-19 JP JP52423998A patent/JP2001504505A/ja not_active Withdrawn
-
1999
- 1999-05-27 NO NO992564A patent/NO992564L/no not_active Application Discontinuation
- 1999-05-27 NO NO992562A patent/NO992562D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001508046A (ja) | 2001-06-19 |
| WO1998023277A1 (de) | 1998-06-04 |
| NO992564D0 (no) | 1999-05-27 |
| DK0941097T3 (da) | 2002-08-19 |
| NZ335990A (en) | 2000-10-27 |
| NO992562L (no) | 1999-05-27 |
| AU713665B2 (en) | 1999-12-09 |
| EP0952837B1 (de) | 2002-09-18 |
| ES2176805T3 (es) | 2002-12-01 |
| NO992562D0 (no) | 1999-05-27 |
| CA2272754A1 (en) | 1998-06-04 |
| NO992564L (no) | 1999-05-27 |
| CA2273341A1 (en) | 1998-06-04 |
| AU714993B2 (en) | 2000-01-13 |
| AU5322998A (en) | 1998-06-22 |
| AU5553198A (en) | 1998-06-22 |
| EP0941097A1 (de) | 1999-09-15 |
| EP0952837A1 (de) | 1999-11-03 |
| JP2001504505A (ja) | 2001-04-03 |
| US6383514B1 (en) | 2002-05-07 |
| WO1998023275A1 (de) | 1998-06-04 |
| DK0952837T3 (da) | 2003-01-27 |
| EP0941097B1 (de) | 2002-05-02 |
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