[go: up one dir, main page]

ES2171233T3 - Uso de eliprodil para la preparacion de un medicamento para el tratamiento de trastornos isquemicos de la retina o el nervio optico. - Google Patents

Uso de eliprodil para la preparacion de un medicamento para el tratamiento de trastornos isquemicos de la retina o el nervio optico.

Info

Publication number
ES2171233T3
ES2171233T3 ES96943986T ES96943986T ES2171233T3 ES 2171233 T3 ES2171233 T3 ES 2171233T3 ES 96943986 T ES96943986 T ES 96943986T ES 96943986 T ES96943986 T ES 96943986T ES 2171233 T3 ES2171233 T3 ES 2171233T3
Authority
ES
Spain
Prior art keywords
eliprodil
retina
disorders
ischemical
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96943986T
Other languages
English (en)
Inventor
Michael A Kapin
Louis Desantis Jr
Bernard Scatton
Salomon Langer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Application granted granted Critical
Publication of ES2171233T3 publication Critical patent/ES2171233T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

SE DESCRIBE EL USO DE ANTAGONISTAS DEL SITIO DE POLIAMINA PARA TRATAR TRASTORNOS ISQUEMICOS DE LA RETINA Y DE LA CABEZA DEL NERVIO OPTICO. SE PREFIEREN ESPECIALMENTE CIERTOS DERIVADOS DE 1 - FENIL - 2 - PIPERIDINOALCANOL, TALES COMO ELIPRODILO Y IFENPRODILO.
ES96943986T 1996-01-02 1996-12-17 Uso de eliprodil para la preparacion de un medicamento para el tratamiento de trastornos isquemicos de la retina o el nervio optico. Expired - Lifetime ES2171233T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58200396A 1996-01-02 1996-01-02

Publications (1)

Publication Number Publication Date
ES2171233T3 true ES2171233T3 (es) 2002-09-01

Family

ID=24327451

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96943986T Expired - Lifetime ES2171233T3 (es) 1996-01-02 1996-12-17 Uso de eliprodil para la preparacion de un medicamento para el tratamiento de trastornos isquemicos de la retina o el nervio optico.

Country Status (11)

Country Link
US (1) US6020352A (es)
EP (1) EP0871446B1 (es)
JP (1) JP2000507205A (es)
AT (1) ATE214605T1 (es)
AU (1) AU716670B2 (es)
CA (1) CA2241913A1 (es)
DE (1) DE69620027T2 (es)
DK (1) DK0871446T3 (es)
ES (1) ES2171233T3 (es)
PT (1) PT871446E (es)
WO (1) WO1997024123A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9620350D0 (en) 1996-09-30 1996-11-13 Maudsley David J Cancer vaccine
WO2000024396A1 (en) * 1998-10-27 2000-05-04 Alcon Laboratories, Inc. Treatment of disorders of the outer retina
US20030212107A1 (en) * 2001-05-10 2003-11-13 Kapin Michael A. R-reliprodil for treating glaucoma
EP1720874A4 (en) * 2004-02-24 2010-03-03 Bioaxone Therapeutique Inc 4-SUBSTITUTED PIPERIDINE DERIVATIVES
GB2432526A (en) * 2005-11-24 2007-05-30 Arakis Ltd Use of ifenprodil for the treatment of ophthalmic diseases
US10149856B2 (en) 2015-01-26 2018-12-11 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US10857157B2 (en) 2015-01-26 2020-12-08 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US10106525B2 (en) 2015-01-26 2018-10-23 BioAxone BioSciences, Inc. Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
US11198680B2 (en) 2016-12-21 2021-12-14 BioAxone BioSciences, Inc. Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
WO2019014322A1 (en) 2017-07-11 2019-01-17 BioAxone BioSciences, Inc. KINASE INHIBITORS FOR THE TREATMENT OF DISEASES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
US5922773A (en) * 1992-12-04 1999-07-13 The Children's Medical Center Corp. Glaucoma treatment

Also Published As

Publication number Publication date
PT871446E (pt) 2002-08-30
CA2241913A1 (en) 1997-07-10
AU1373997A (en) 1997-07-28
DE69620027T2 (de) 2002-09-05
JP2000507205A (ja) 2000-06-13
US6020352A (en) 2000-02-01
AU716670B2 (en) 2000-03-02
HK1016068A1 (en) 1999-10-29
EP0871446B1 (en) 2002-03-20
WO1997024123A1 (en) 1997-07-10
DK0871446T3 (da) 2002-04-15
EP0871446A1 (en) 1998-10-21
ATE214605T1 (de) 2002-04-15
DE69620027D1 (de) 2002-04-25

Similar Documents

Publication Publication Date Title
DE69027057D1 (de) Retinal, dessen Derivate und deren therapeutische Verwendung
CY1105460T1 (el) Παραγωγα ακετυλενιου που εχουν mlgur 5 ανταγωνιστικη δραση
PT777483E (pt) Metodos e meio para administrar farmacos
BR9404203A (pt) Compostos, processo para a preparação dos mesmos, medicamento, uso dos ditos compostos e processo de tratamento ou prevenção de distúrbios nervosos centrais
DK0725779T3 (da) Hidtil ukendte (R)-5-Carbamoyl-8-fluor-3-N,N-disubstitueret-amino-3,4-dihydro-2H-1-benzopyraner
ES2173111T3 (es) Uso de fenserina para la preparacion de medicamentos para el tratamiento de desordenes cognoscitivos.
BR9507073A (pt) Composto processos para preparar o mesmo e para tratar uma doença no sistema nervoso central composiçao farmacêutica e uso do composto
TR200000149T2 (tr) Serebral nörovasküler bozuklukların, müsküler baş ağrılarının önlenmesine yönelik kompozisyonlar
MX9704037A (es) 1,1-dioxidos de 1,2,5-tiadiazolidin-3-ona 2-substituida y composiciones y metodo de uso de los mismos.
BR9908510A (pt) Uso de um composto, composto, processo para a preparação de um composto, composição farmacêutica, e, processo de tratar um paciente que sofre de, ou em risco de, uma doença micobacteriana
DK0520200T3 (da) Imadazol-forbindelser, deres fremstilling og anvendelse
ES2171233T3 (es) Uso de eliprodil para la preparacion de un medicamento para el tratamiento de trastornos isquemicos de la retina o el nervio optico.
AR023687A1 (es) Una composicion para el tratamiento de desordenes de la retina externa y el uso de un antagonista de glutamato para la manufactura de un medicamento parael tratamiento de desordenes de la retina externa
BG105962A (en) Use of saredutant and the pharmaceutically acceptable salts thereof to produce medicaments used to treat or prevent mood disorders, adjustment disorders or mixed anxiety-depression disorders
PT656209E (pt) Derivados de melatonina para uso no tratamento de perturbacoes de dessincronizacao
PT655243E (pt) Derivados da melatonina para utilizacao no tratamento de disturbios do sono
BR9713044A (pt) Composto, uso de um composto, processo para sua preparação,e, formulação farmacêutica.
AR030346A1 (es) Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
BR9812531A (pt) Combinação de componentes, preparação farmacêutica, produção desta, e, uso da combinação ou da preparação farmacêutica
BR9406865A (pt) Uso de um sal farmaceuticamente aceitável de ropivacaina na fabricaçao de um produto farmaceutico processo para o tratamento de uma pessoa necessitando de alivio da dor e preparaçao farmaceutica
BR0015938A (pt) Uso de antagonistas beta-adrenoceptores para a fabricação de um medicamento para o tratamento de desordens da retina externa
BR9508021A (pt) Composição farmacêutica para o tratamento de distúrbios esquizofrênicos, uso de um agente imunossupressor, e, processo de tratamento de um paciente esquizofrênico
MX9405209A (es) Uso de las n-(piridinil)-1h-indol-1-aminas en la preparacion de unmedicamento para el tratamiento de desordenes obsesivo-compulsivos.
DE69510933D1 (de) Amidderivate und ihre therapeutische anwendung
PT91415A (pt) Processo para a preparacao de novos derivados de furiltiazol

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 871446

Country of ref document: ES