ES2170143T3 - Composiciones que comprenden halofantrina en una forma especial. - Google Patents
Composiciones que comprenden halofantrina en una forma especial.Info
- Publication number
- ES2170143T3 ES2170143T3 ES95915852T ES95915852T ES2170143T3 ES 2170143 T3 ES2170143 T3 ES 2170143T3 ES 95915852 T ES95915852 T ES 95915852T ES 95915852 T ES95915852 T ES 95915852T ES 2170143 T3 ES2170143 T3 ES 2170143T3
- Authority
- ES
- Spain
- Prior art keywords
- halofantrine
- compositions
- special form
- lipid
- oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229960003242 halofantrine Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- FOHHNHSLJDZUGQ-UHFFFAOYSA-N 3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)-9-phenanthrenyl]-1-propanol Chemical compound FC(F)(F)C1=CC=C2C(C(O)CCN(CCCC)CCCC)=CC3=C(Cl)C=C(Cl)C=C3C2=C1 FOHHNHSLJDZUGQ-UHFFFAOYSA-N 0.000 title 1
- FOHHNHSLJDZUGQ-VWLOTQADSA-N Halofantrine Chemical compound FC(F)(F)C1=CC=C2C([C@@H](O)CCN(CCCC)CCCC)=CC3=C(Cl)C=C(Cl)C=C3C2=C1 FOHHNHSLJDZUGQ-VWLOTQADSA-N 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA INVENCION HACE REFERENCIA AL USO DE UNA BASE LIBRE DE HALOFANTRINA EN EL TRATAMIENTO DE LAS INFECCIONES POR MALARIA. SE DESCRIBEN ESPECIALMENTE LAS FORMULAS BASADAS EN LIPIDOS PARA USO ORAL E INYECTABLE.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9406858A GB9406858D0 (en) | 1994-04-07 | 1994-04-07 | New use and formulations |
| GB9416404A GB9416404D0 (en) | 1994-08-13 | 1994-08-13 | New use and formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2170143T3 true ES2170143T3 (es) | 2002-08-01 |
Family
ID=26304653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95915852T Expired - Lifetime ES2170143T3 (es) | 1994-04-07 | 1995-04-04 | Composiciones que comprenden halofantrina en una forma especial. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5968987A (es) |
| EP (1) | EP0754045B1 (es) |
| JP (1) | JPH09512794A (es) |
| CN (1) | CN1145030A (es) |
| AT (1) | ATE213937T1 (es) |
| AU (1) | AU685263B2 (es) |
| BR (1) | BR9507437A (es) |
| CA (1) | CA2187185A1 (es) |
| CZ (1) | CZ293696A3 (es) |
| DE (1) | DE69525740T2 (es) |
| ES (1) | ES2170143T3 (es) |
| HU (1) | HUT76051A (es) |
| NO (1) | NO964238L (es) |
| NZ (1) | NZ284068A (es) |
| PL (1) | PL179608B1 (es) |
| WO (1) | WO1995027492A1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5340298A (en) * | 1996-12-27 | 1998-07-31 | Takeda Chemical Industries Ltd. | Stabilized tricyclic compound |
| US6979456B1 (en) * | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| IN191696B (es) * | 1999-02-12 | 2003-12-20 | Council Scient Ind Res | |
| US6616942B1 (en) * | 1999-03-29 | 2003-09-09 | Soft Gel Technologies, Inc. | Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing |
| US6759058B1 (en) * | 2001-04-25 | 2004-07-06 | Western Center For Drug Development College Of Pharmacy Western University Of Health Sciences | Enteric-coated proliposomal formulations for poorly water soluble drugs |
| AUPR573001A0 (en) * | 2001-06-15 | 2001-07-12 | Glaxo Wellcome Australia Ltd | Lymphatic drug delivery system |
| AU2002343555A1 (en) | 2001-11-14 | 2003-05-26 | Texas Tech University | Eutectic-based self-nanoemulsified drug delivery system |
| US20060148776A1 (en) * | 2003-03-13 | 2006-07-06 | Conforma Therapeutics Corporation | Drug formulations having long and medium chain triglycerides |
| US8124072B2 (en) | 2003-09-29 | 2012-02-28 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| AU2004277951B2 (en) | 2003-09-29 | 2010-11-11 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| US20050220866A1 (en) * | 2004-04-02 | 2005-10-06 | Dr. Reddy's Laboratories Limited | Novel capsule formulations of etoposide for oral use |
| US8343541B2 (en) | 2007-03-15 | 2013-01-01 | Soft Gel Technologies, Inc. | Ubiquinol and alpha lipoic acid compositions |
| SA109300195B1 (ar) | 2008-03-28 | 2013-04-20 | Astrazeneca Ab | تركيبة صيدلانية جديدة مضادة للسرطان |
| CA2690490C (en) * | 2010-01-19 | 2012-06-26 | Accucaps Industries Limited | Pharmaceutical formulations of loratadine for encapsulation and combinations thereof |
| US9309136B2 (en) * | 2014-06-12 | 2016-04-12 | Tersus Environmental, Llc | Bioremediation of soil and groundwater |
| JP6723166B2 (ja) * | 2014-06-19 | 2020-07-15 | ソルラル ファーマ エーピーエス | 親油性の化合物の固体経口剤形 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4818767A (en) * | 1983-11-02 | 1989-04-04 | Smithkline Beckman Corporation | Quinate salts of antimalarial phenanthrenemethanol compounds |
| US4507288A (en) * | 1983-09-16 | 1985-03-26 | Smithkline Beckman Corporation | β-Glycerophosphate salts of antimalarial phenanthrenemethanol compounds |
| US5278173A (en) * | 1988-06-30 | 1994-01-11 | Davis Michael H | Method of inhibiting the activity of human immunodeficiency virus (HIV) in vivo |
| WO1993001809A1 (en) * | 1991-07-15 | 1993-02-04 | Smithkline Beecham Plc | Pharmaceutical formulations comprised of micronised halofantrine |
-
1995
- 1995-04-04 EP EP95915852A patent/EP0754045B1/en not_active Expired - Lifetime
- 1995-04-04 ES ES95915852T patent/ES2170143T3/es not_active Expired - Lifetime
- 1995-04-04 PL PL95316656A patent/PL179608B1/pl unknown
- 1995-04-04 JP JP7526060A patent/JPH09512794A/ja active Pending
- 1995-04-04 CZ CZ962936A patent/CZ293696A3/cs unknown
- 1995-04-04 AU AU22568/95A patent/AU685263B2/en not_active Ceased
- 1995-04-04 AT AT95915852T patent/ATE213937T1/de not_active IP Right Cessation
- 1995-04-04 CA CA002187185A patent/CA2187185A1/en not_active Abandoned
- 1995-04-04 HU HU9602740A patent/HUT76051A/hu unknown
- 1995-04-04 WO PCT/EP1995/001257 patent/WO1995027492A1/en not_active Ceased
- 1995-04-04 BR BR9507437A patent/BR9507437A/pt not_active Application Discontinuation
- 1995-04-04 CN CN95192440A patent/CN1145030A/zh active Pending
- 1995-04-04 NZ NZ284068A patent/NZ284068A/en unknown
- 1995-04-04 DE DE69525740T patent/DE69525740T2/de not_active Expired - Fee Related
-
1996
- 1996-10-04 NO NO964238A patent/NO964238L/no not_active Application Discontinuation
-
1997
- 1997-10-15 US US08/950,459 patent/US5968987A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2256895A (en) | 1995-10-30 |
| DE69525740T2 (de) | 2002-10-24 |
| WO1995027492A1 (en) | 1995-10-19 |
| MX9604611A (es) | 1997-11-29 |
| AU685263B2 (en) | 1998-01-15 |
| HUT76051A (en) | 1997-06-30 |
| CN1145030A (zh) | 1997-03-12 |
| PL316656A1 (en) | 1997-02-03 |
| PL179608B1 (pl) | 2000-10-31 |
| NO964238D0 (no) | 1996-10-04 |
| NZ284068A (en) | 1998-06-26 |
| DE69525740D1 (de) | 2002-04-11 |
| ATE213937T1 (de) | 2002-03-15 |
| EP0754045A1 (en) | 1997-01-22 |
| NO964238L (no) | 1996-10-04 |
| EP0754045B1 (en) | 2002-03-06 |
| HU9602740D0 (en) | 1996-11-28 |
| BR9507437A (pt) | 1997-09-16 |
| US5968987A (en) | 1999-10-19 |
| CA2187185A1 (en) | 1995-10-19 |
| CZ293696A3 (en) | 1997-01-15 |
| JPH09512794A (ja) | 1997-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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