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ES2166990T3 - Procedimiento para la preparacion de derivados de 4-metil-bifenilo. - Google Patents

Procedimiento para la preparacion de derivados de 4-metil-bifenilo.

Info

Publication number
ES2166990T3
ES2166990T3 ES97919122T ES97919122T ES2166990T3 ES 2166990 T3 ES2166990 T3 ES 2166990T3 ES 97919122 T ES97919122 T ES 97919122T ES 97919122 T ES97919122 T ES 97919122T ES 2166990 T3 ES2166990 T3 ES 2166990T3
Authority
ES
Spain
Prior art keywords
preparation
bifenyl
derivatives
methyl
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97919122T
Other languages
English (en)
Inventor
Mouad Alami
Gerard Cahiez
Bertrand Castro
Jean-Robert Dormoy
Eric Riguet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Application granted granted Critical
Publication of ES2166990T3 publication Critical patent/ES2166990T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 4 - METIL - BIFENILO DE FORMULA GENERAL (I) EN LA QUE R REPRESENTA UN GRUPO CIANO O TETRAZOILO PROTEGIDO DE FORMULA (A), EN LA QUE R 1 SITUADO EN POSICION 1 O 2 DEL GRUPO TETRAZOILO REPRESENTA UN GRUPO PROTECTOR, CARACTERIZADO PORQUE SE HACE REACCIONAR UN HALOBENCENO DE FORMULA (II) EN LA QUE HAL REPRESENTA HALOGENO Y R TIENE LA MISMA SIGNIFICACION QUE ANTERIORMENTE, CON UN HALOGENURO DE P - TOLIMAGNESIO EN PRESENCIA DE UN POLIETER, LINEAL O RAMIFICADO, Y DE UN CATALIZADOR QUE CONTIENE UN METAL DE TRANSICION.
ES97919122T 1996-09-20 1997-09-17 Procedimiento para la preparacion de derivados de 4-metil-bifenilo. Expired - Lifetime ES2166990T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9611514A FR2753705B1 (fr) 1996-09-20 1996-09-20 Procede pour la preparation de derives de 4-methyl-biphenyle

Publications (1)

Publication Number Publication Date
ES2166990T3 true ES2166990T3 (es) 2002-05-01

Family

ID=9495937

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97919122T Expired - Lifetime ES2166990T3 (es) 1996-09-20 1997-09-17 Procedimiento para la preparacion de derivados de 4-metil-bifenilo.

Country Status (12)

Country Link
US (1) US6407253B1 (es)
EP (1) EP0931057B1 (es)
JP (1) JP3604702B2 (es)
AT (1) ATE209181T1 (es)
AU (1) AU4306497A (es)
BR (1) BR9713208B1 (es)
CA (1) CA2265559C (es)
DE (1) DE69709773T2 (es)
ES (1) ES2166990T3 (es)
FR (1) FR2753705B1 (es)
NO (1) NO326192B1 (es)
WO (1) WO1998012174A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517925A (ja) * 2003-01-14 2006-08-03 メルク　エンド　カムパニー　インコーポレーテッド Ａβ４２低下薬としてのジェミナル二置換ＮＳＡＩＤ誘導体
CN114733575B (zh) * 2022-04-25 2024-04-09 浙江天宇药业股份有限公司 一种钯负载的分子筛催化剂及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
US5270317A (en) 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
US5252753A (en) * 1991-11-01 1993-10-12 Ortho Pharmaceutical Corporation Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof
FR2689887B1 (fr) * 1992-04-13 1995-06-23 Sanofi Elf Procede de preparation d'un derive de biphenyle.
JPH08109143A (ja) * 1994-08-17 1996-04-30 Asahi Glass Co Ltd ビフェニル化合物の製造方法
ES2160720T3 (es) * 1994-10-27 2001-11-16 Novartis Ag Procedimiento para la preparacion de tetrazoles.
JP3763869B2 (ja) * 1994-12-26 2006-04-05 東ソー・ファインケム株式会社 ビフェニル化合物の製造方法

Also Published As

Publication number Publication date
NO326192B1 (no) 2008-10-13
BR9713208B1 (pt) 2010-06-15
US6407253B1 (en) 2002-06-18
ATE209181T1 (de) 2001-12-15
NO991355L (no) 1999-03-19
CA2265559A1 (fr) 1998-03-26
AU4306497A (en) 1998-04-14
EP0931057B1 (fr) 2001-11-21
JP3604702B2 (ja) 2004-12-22
NO991355D0 (no) 1999-03-19
JP2000503025A (ja) 2000-03-14
CA2265559C (fr) 2003-06-03
DE69709773T2 (de) 2002-08-08
FR2753705A1 (fr) 1998-03-27
FR2753705B1 (fr) 1999-08-06
EP0931057A1 (fr) 1999-07-28
WO1998012174A1 (fr) 1998-03-26
BR9713208A (pt) 2000-04-04
DE69709773D1 (de) 2002-02-21

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