[go: up one dir, main page]

ES2161669T1 - Test de glucosa 13c por aliento para el diagnostico de indicaciones de diabetes y la monitorizacion del control glicemico. - Google Patents

Test de glucosa 13c por aliento para el diagnostico de indicaciones de diabetes y la monitorizacion del control glicemico.

Info

Publication number
ES2161669T1
ES2161669T1 ES99919475T ES99919475T ES2161669T1 ES 2161669 T1 ES2161669 T1 ES 2161669T1 ES 99919475 T ES99919475 T ES 99919475T ES 99919475 T ES99919475 T ES 99919475T ES 2161669 T1 ES2161669 T1 ES 2161669T1
Authority
ES
Spain
Prior art keywords
indications
diabetes
diagnosis
monitoring
glycemic control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ES99919475T
Other languages
English (en)
Inventor
Randall W Yatscoff
Robert T Foster
Launa J Aspeslet
Richard Lewanczuk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Isotechnika Inc
Original Assignee
Isotechnika Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isotechnika Inc filed Critical Isotechnika Inc
Publication of ES2161669T1 publication Critical patent/ES2161669T1/es
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206Administration of radioactive gases, aerosols or breath tests
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/0813Measurement of pulmonary parameters by tracers, e.g. radioactive tracers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/083Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836Measuring rate of CO2 production
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/497Physical analysis of biological material of gaseous biological material, e.g. breath
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/104998Glucose, ketone, nitrate standard or control
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/13Tracers or tags
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25875Gaseous sample or with change of physical state

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Food Science & Technology (AREA)
  • Obesity (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Atmospheric Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Equipo de diagnóstico para la determinación del control glicémico en un paciente, que comprende: una cantidad predeterminada de glucosa enriquecida con 13 C, y un recipiente colector de aliento.
ES99919475T 1998-05-06 1999-05-06 Test de glucosa 13c por aliento para el diagnostico de indicaciones de diabetes y la monitorizacion del control glicemico. Pending ES2161669T1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8448298P 1998-05-06 1998-05-06

Publications (1)

Publication Number Publication Date
ES2161669T1 true ES2161669T1 (es) 2001-12-16

Family

ID=22185237

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99919475T Pending ES2161669T1 (es) 1998-05-06 1999-05-06 Test de glucosa 13c por aliento para el diagnostico de indicaciones de diabetes y la monitorizacion del control glicemico.

Country Status (8)

Country Link
US (3) US6468802B1 (es)
EP (1) EP1075286A2 (es)
JP (3) JP2002513911A (es)
AU (1) AU3725199A (es)
CA (1) CA2331812C (es)
DE (1) DE1075286T1 (es)
ES (1) ES2161669T1 (es)
WO (1) WO1999056790A2 (es)

Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5910403A (en) * 1997-05-15 1999-06-08 The Regents Of University Of California Methods for measuring cellular proliferation and destruction rates in vitro and in vivo
CA2250485C (en) * 1997-10-21 2008-04-29 Tokyo Gas Co., Ltd. Diagnostic agent for diabetes
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
CA2331812C (en) * 1998-05-06 2006-08-22 Randall W. Yatscoff 13c glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control
US6461870B2 (en) * 1998-05-06 2002-10-08 Isotechnika Inc. 13C glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control
DE10028548C1 (de) * 2000-06-09 2001-08-30 Inst Chemo Biosensorik Verfahren zum Nachweis von alpha-Oxoaldehyden in Vollblut, Blutplasma und/oder Serum eines Patienten
FR2815074B1 (fr) * 2000-10-10 2002-12-06 Inst Francais Du Petrole Methode d'analyse et de mesures chimique et isotopique sur des constituants transportes par un fluide de forage
DE10057832C1 (de) 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
CA2448905C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Blood sampling apparatus and method
EP1404233B1 (en) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
WO2002100461A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US7537571B2 (en) 2001-06-12 2009-05-26 Pelikan Technologies, Inc. Integrated blood sampling analysis system with multi-use sampling module
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
CA2448790C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Electric lancet actuator
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US7344894B2 (en) 2001-10-16 2008-03-18 Agilent Technologies, Inc. Thermal regulation of fluidic samples within a diagnostic cartridge
IL161498A0 (en) 2001-10-24 2004-09-27 Univ California Measurement of protein synthesis rates in humans and experimental system by use of isotopically labeled water
US7449171B2 (en) * 2002-02-12 2008-11-11 The Regents Of The University Of California Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolic products
AU2003234688A1 (en) * 2002-04-05 2003-10-27 The Regents Of The University Of California Method for isolating and measuring proliferation of long-term label retaining cells and stem cells
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7481776B2 (en) 2002-04-19 2009-01-27 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7410468B2 (en) 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7563232B2 (en) 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7582099B2 (en) 2002-04-19 2009-09-01 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US7374544B2 (en) 2002-04-19 2008-05-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7524293B2 (en) 2002-04-19 2009-04-28 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
EP1546364A4 (en) 2002-07-30 2006-09-06 Univ California METHOD FOR THE AUTOMATIC MEASUREMENT OF THE MOLECULAR FLOW RATE SPEED OF THE PROTEOM OR ORGANOMA BY MEANS OF MASS SPECTROMETRY
CN100402093C (zh) * 2002-08-26 2008-07-16 马永健 用于医学呼气诊断的药物
US20060105339A1 (en) * 2002-09-04 2006-05-18 Marc Hellerstein Methods for measuring the rates of replication and death of microbial infectious agents in an infected
AU2003267283B2 (en) * 2002-09-13 2009-09-03 The Regents Of The University Of California Methods for measuring rates of reserve cholesterol transport in vivo, as an index of anti-atherogenesis
US20070248540A1 (en) * 2002-09-16 2007-10-25 The Regents Of The University Of California Biochemical methods for measuring metabolic fitness of tissues or whole organisms
EP1545628A4 (en) * 2002-09-16 2010-07-28 Univ California BIOCHEMICAL METHOD FOR MEASURING THE METABOLIC FITNESS OF WOVEN OR THE WHOLE ORGANISM
WO2004042360A2 (en) * 2002-11-04 2004-05-21 The Regents Of The Univeristy Of California Deuterated glucose or fat tolerance tests for high-throughput measurement of the metabolism of sugars or fatty acids in the body
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US20040137637A1 (en) * 2003-01-13 2004-07-15 Chuji Wang Breath gas analyzer for diagnosing diabetes and method of use thereof
WO2004107964A2 (en) 2003-06-06 2004-12-16 Pelikan Technologies, Inc. Blood harvesting device with electronic control
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
EP1635700B1 (en) 2003-06-13 2016-03-09 Sanofi-Aventis Deutschland GmbH Apparatus for a point of care device
US7262020B2 (en) * 2003-07-03 2007-08-28 The Regents Of The University Of California Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
US20050202406A1 (en) * 2003-11-25 2005-09-15 The Regents Of The University Of California Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
TW200538738A (en) 2004-02-20 2005-12-01 Univ California Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
US20050201937A1 (en) * 2004-03-11 2005-09-15 The Regents Of The University Of California Temporal or spatial characterization of biosynthetic events in living organisms by isotopic fingerprinting under conditions of imposed isotopic gradients
WO2005094327A2 (en) * 2004-03-29 2005-10-13 The Regents Of The University Of California Isolation of epithelial cells or their biochemical contents from excreta after in vivo isotopic labeling
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US20060251576A1 (en) * 2005-05-03 2006-11-09 The Regents Of The University Of California Methods for measuring cholesterol metabolism and transport
TW200711660A (en) 2005-06-10 2007-04-01 Univ California Monitoring two dimensions of diabetes pathogenesis separately or concurrently (insulin sensitivity and beta-cell sufficiency): uses in diagnosis, prognosis, assessment of disease risk, and drug development
GB0604647D0 (en) 2006-03-08 2006-04-19 Shchepinov Mikhail Stabilized food supplements and their derivatives
WO2007142644A1 (en) * 2006-06-08 2007-12-13 Braun Charles L Spectroscopic breath profile analysis device and uses thereof for facilitating diagnosis of medical conditions
US20080306353A1 (en) * 2006-11-03 2008-12-11 Douglas Joel S Calculation device for metabolic control of critically ill and/or diabetic patients
GB0716427D0 (en) * 2007-08-23 2007-10-03 Smartsensor Telemed Ltd Glucose tolerance test device
WO2009114814A2 (en) 2008-03-14 2009-09-17 Retrotope, Inc. Therapeutic substances that modulate genome methylation
CA2715036A1 (en) 2008-03-14 2009-09-17 Retrotope, Inc. Therapies for cancer using isotopically substituted lysine
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US20100279418A1 (en) * 2009-05-04 2010-11-04 Loren Robert Larson Glucose meter adaptable for use with handheld devices, and associated communication network
AU2010313249B2 (en) 2009-10-30 2016-05-19 Biojiva Llc Alleviating oxidative stress disorders with PUFA derivatives
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
DK2701697T3 (da) 2011-04-26 2020-06-29 Retrotope Inc Oxidative nethindesygdomme
CA2834342C (en) 2011-04-26 2021-08-31 Retrotope, Inc. Impaired energy processing disorders and mitochondrial deficiency
US10154983B2 (en) 2011-04-26 2018-12-18 Retrotope, Inc. Neurodegenerative disorders and muscle diseases implicating PUFAs
KR102110175B1 (ko) 2011-04-26 2020-05-13 레트로토프 인코포레이티드 Pufa 산화와 관련된 장애
EP2753707A4 (en) 2011-09-08 2015-03-04 Univ California METABOLIC FLOW MEASUREMENT, IMAGING AND MICROSCOPY
ES2668678T3 (es) 2011-12-07 2018-05-21 Glaxosmithkline Llc Procedimiento de determinación de la masa muscular esquelética corporal total
JP6175492B2 (ja) 2012-04-30 2017-08-02 カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ 呼気中アセトン検出用センサ組成物
US10228365B2 (en) 2012-08-20 2019-03-12 Otsuka Pharmaceutical Co., Ltd. Method for measuring carbohydrate metabolism ability, and composition for use in said method
US10444229B2 (en) 2013-03-15 2019-10-15 Otsuka Pharmaceutical Co., Ltd. Method of measuring insulin resistance with fatty acid combustion, and composition used herein
US9134319B2 (en) 2013-03-15 2015-09-15 The Regents Of The University Of California Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivo
EP2992826B1 (en) 2013-05-02 2023-01-04 Atonarp Inc. Monitor and system for monitoring living organisms
JP6542219B2 (ja) * 2013-12-03 2019-07-10 プレジデント アンド フェローズ オブ ハーバード カレッジ 妊娠性糖尿病の評価のための方法および試薬
US9753041B2 (en) * 2014-04-21 2017-09-05 Univeristy Of South Florida Salivary inflammatory biomarkers associated with glycemic control and oral health
JP6685906B2 (ja) * 2014-07-09 2020-04-22 大塚製薬株式会社 肝疾患被験者のエネルギー低栄養評価
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
EP3020437B1 (en) 2014-11-13 2023-06-07 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Controlling a flow through a pneumatic system
EP3950649A1 (en) 2015-11-23 2022-02-09 Retrotope, Inc. Site-specific isotopic labeling of 1, 4-diene systems
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
JP6721408B2 (ja) * 2016-05-20 2020-07-15 株式会社Nttドコモ 判定装置
WO2018088521A1 (ja) 2016-11-11 2018-05-17 大塚製薬株式会社 肝の糖取込み能評価方法
EP3567356B1 (en) * 2018-05-07 2021-02-24 Inficon GmbH Sniffing leak detector with switching valve and buffer chamber
KR20220143931A (ko) 2020-02-21 2022-10-25 레트로토프 인코포레이티드 고도불포화 지방산 및 이의 유도체의 동위원소 변형을 위한 공정
US12109194B2 (en) 2021-02-05 2024-10-08 Biojiva Llc Synergistic combination therapy for treating ALS
US20250090103A1 (en) * 2023-09-18 2025-03-20 Frank Healthcare Advisors, Llc Early recognition of change to pathophysiologic state of dysglycemia

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912178A (en) * 1994-02-16 1999-06-15 Wisconsin Alumni Research Foundation Passive measurement of isotopes to monitor health
EP0826377B1 (en) 1996-08-27 2002-11-06 Tokyo Gas Co., Ltd. Diagnostic agent for diabetes
ES2120903B1 (es) * 1996-11-12 1999-05-16 Isomed S L Metodo y kit para la deteccion de helicobacter pylori.
US5962335A (en) * 1997-01-03 1999-10-05 Oridion Medical Ltd. Breath test for detection of drug metabolism
US6067989A (en) * 1997-02-26 2000-05-30 Oridion Medical, Ltd. Breath test for the diagnosis of Helicobacter pylori infection in the gastrointestinal tract
CA2250485C (en) 1997-10-21 2008-04-29 Tokyo Gas Co., Ltd. Diagnostic agent for diabetes
US6461870B2 (en) * 1998-05-06 2002-10-08 Isotechnika Inc. 13C glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control
CA2331812C (en) * 1998-05-06 2006-08-22 Randall W. Yatscoff 13c glucose breath test for the diagnosis of diabetic indications and monitoring glycemic control

Also Published As

Publication number Publication date
US20030044993A1 (en) 2003-03-06
US6602715B2 (en) 2003-08-05
DE1075286T1 (de) 2002-05-23
WO1999056790A2 (en) 1999-11-11
JP2007192831A (ja) 2007-08-02
WO1999056790A3 (en) 1999-12-16
US20050147560A1 (en) 2005-07-07
US6468802B1 (en) 2002-10-22
AU3725199A (en) 1999-11-23
JP2002513911A (ja) 2002-05-14
CA2331812C (en) 2006-08-22
CA2331812A1 (en) 1999-11-11
EP1075286A2 (en) 2001-02-14
US7118919B2 (en) 2006-10-10
JP2008292506A (ja) 2008-12-04

Similar Documents

Publication Publication Date Title
ES2161669T1 (es) Test de glucosa 13c por aliento para el diagnostico de indicaciones de diabetes y la monitorizacion del control glicemico.
Howanitz et al. Physician goals and laboratory test turnaround times. A College of American Pathologists Q-Probes study of 2763 clinicians and 722 institutions
EP1393764A3 (en) Integrated system including medication delivery pen, blood monitoring device, and lancer
EP2008581A3 (en) Patient monitoring, diagnosis, and/or therapy systems and methods
EP2131738B1 (en) A method and apparatus for enhancement and quality improvement of analyte measurement signals
ES2138004T3 (es) Procedimiento para la determinacion de la funcion cardiovascular.
Cox et al. Disruptive effects of acute hypoglycemia on speed of cognitive and motor performance
WO1997002050A3 (en) Solid oral diagnostic test meal and methods of use thereof
DE102005057757A1 (de) Integrale Vorrichtung zur Bestimmung physiologischer Signale
CN111214216B (zh) 一种基于手掌表面微电信号变化获取心率的采集装置
Randall et al. Relations between personality measures and physiological reactivity using a perceptual motor challenge
WO2002053022A3 (en) A system and a method for monitoring the effectiveness of a medical treatment
Krishnaswami et al. Coronary angiographic findings in patients with diabetes: an exercise in cardiovascular epidemiology.
Allman Recidivism and rehabilitation rates for 135 criminally insane offenders.
Šapina et al. Poincaré plot indices as a marker for acute pain response in newborns
Strylewicz et al. An evaluation of Bayesian networks for the real-time detection of errors in the clinical laboratory
Baron et al. Diurnal and circannual variation in platelet 3H-imipramine binding: comparative data on normal and affectively ill subjects
Vinothini et al. A Survey Report on Various Non-Invasive Glucose Monitoring Methods
Chan et al. Heart rate fragmentation: A novel analytic approach to early allostatic load detection among healthy adults
Hinz et al. Stability of cardiovascular reactions to mental stressors in repeated studies.
Bryce et al. Problems in prediction of a schizophrenic population
Robbins et al. Body mass index and adiposity in active duty military members
Ahmed et al. Assessment of home glucose monitoring system in primary health care system; where are we?
Aronov Code for evaluating the results of a physical load electrocardiographic test
Hansen The relationship of subliminally activated psychodynamic conflict to anorexic performance on a lexical decision task.