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ES2160161T3 - Composiciones farmaceuticas derivadas de geles basados en microemulsiones, metodo para su preparacion y nuevos geles basados en microemulsiones. - Google Patents

Composiciones farmaceuticas derivadas de geles basados en microemulsiones, metodo para su preparacion y nuevos geles basados en microemulsiones.

Info

Publication number
ES2160161T3
ES2160161T3 ES95916686T ES95916686T ES2160161T3 ES 2160161 T3 ES2160161 T3 ES 2160161T3 ES 95916686 T ES95916686 T ES 95916686T ES 95916686 T ES95916686 T ES 95916686T ES 2160161 T3 ES2160161 T3 ES 2160161T3
Authority
ES
Spain
Prior art keywords
component
microemulsion
hydrophilic
lipofilic
based gels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95916686T
Other languages
English (en)
Inventor
Sune Backlund
Folke Eriksson
Maria Rantala
Pertti Rantala
Kari Varho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Oy
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Application granted granted Critical
Publication of ES2160161T3 publication Critical patent/ES2160161T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Colloid Chemistry (AREA)

Abstract

LA INVENCION HACE REFERENCIA A UNA COMPOSICION FARMACEUTICA QUE INCLUYE UNA MICROEMULSION HECHA DE UN COMPONENTE HIDROFILICO, UN COMPONENTE LIPOFILICO, UN SURFACTANTE Y UN MEDICAMENTO, DE FORMA QUE EL COMPONENTE HIDROFILICO, EL COMPONENTE LIPOFILICO, Y EL SURFACTANTE FORMAN, CUANDO SE EXAMINAN EN UNA ESCALA MACROSCOPICA, UNA SOLUCION DE UNA FASE. EL COMPONENTE HIDROFILICO SE DISPERSA COMO GOTITAS COLOIDALES EN EL COMPONENTE LIPOFILICO, O EL COMPONENTE LIPOFILICO SE DISPERSA COMO GOTITAS COLOIDALES EN EL COMPONENTE HIDROFILICO. EN OTRA ALTERNATIVA LOS COMPONENTES HIDROFILICOS Y LIPOFILICOS FORMAN UNA MICROEMULSION CON ESTRUCTURA BICONTINUA DE FORMA QUE DICHOS COMPONENTES FORMAN CANALES ADYACENTES ALARGADOS. EL MEDICAMENTO SE DISUELVE EN EL COMPONENTE DISPERSADO O, EN EL CASO DE UNA MICROEMULSION CON UN ESTRUCTURA BICONTINUA, EN EL COMPONENTE HIDROFILICO O LIPOFILICO. LA MICROEMULSION SE ESTABILIZA MEDIANTE EL SURFACTANTE. ES CARACTERISTICO AÑADIR UN GELIFICADOR Y AGUA A LA EMULSION DANDOLE ASI A ESTA LA FORMA DE GEL.
ES95916686T 1994-05-24 1995-04-28 Composiciones farmaceuticas derivadas de geles basados en microemulsiones, metodo para su preparacion y nuevos geles basados en microemulsiones. Expired - Lifetime ES2160161T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI942387A FI100692B (fi) 1994-05-24 1994-05-24 Menetelmä farmaseuttisten koostumusten valmistamiseksi, jolloin koostu mukset pohjautuvat mikroemulsiogeeleihin sekä uusia mikroemulsioihin p ohjautuvia geelejä

Publications (1)

Publication Number Publication Date
ES2160161T3 true ES2160161T3 (es) 2001-11-01

Family

ID=8540757

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95916686T Expired - Lifetime ES2160161T3 (es) 1994-05-24 1995-04-28 Composiciones farmaceuticas derivadas de geles basados en microemulsiones, metodo para su preparacion y nuevos geles basados en microemulsiones.

Country Status (13)

Country Link
US (1) US6004580A (es)
EP (1) EP0760651B1 (es)
JP (1) JPH10500675A (es)
AT (1) ATE202699T1 (es)
AU (1) AU2309195A (es)
CA (1) CA2190869A1 (es)
DE (1) DE69521611T2 (es)
DK (1) DK0760651T3 (es)
ES (1) ES2160161T3 (es)
FI (1) FI100692B (es)
GR (1) GR3036681T3 (es)
PT (1) PT760651E (es)
WO (1) WO1995031969A1 (es)

Families Citing this family (34)

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Publication number Priority date Publication date Assignee Title
GB2305603A (en) * 1995-09-26 1997-04-16 Allied Medical Group Topical cooling gels for reducing excess body fat
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US5686133A (en) * 1996-01-31 1997-11-11 Port Systems, L.L.C. Water soluble pharmaceutical coating and method for producing coated pharmaceuticals
GR1002706B (el) * 1996-05-22 1997-05-26 Μικρογαλακτωματα λεκιθινης περιεχοντα πρωτεολυτικα ενζυμα α-χυμοθρυψινης η θρυψινη και μεθοδος μονιμης ενζυμικης αποτριχωσης.
DE19641672A1 (de) * 1996-10-10 1998-04-16 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen auf der Basis von ethylenoxidfreien und propylenoxidfreien Emulgatoren zur Herstellung von Mikroemulsionsgelen
DE19810655A1 (de) * 1998-03-12 1999-09-16 Univ Eberhard Karls Arzneimittel mit einem Gehalt an Ciclosporin
JP2002540080A (ja) * 1999-03-19 2002-11-26 パーカー ヒューズ インスティテュート ゲルミクロ乳濁液製剤
US7064114B2 (en) 1999-03-19 2006-06-20 Parker Hughes Institute Gel-microemulsion formulations
US7919113B2 (en) * 1999-12-30 2011-04-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Dispersible concentrate lipospheres for delivery of active agents
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US7060672B2 (en) * 2001-10-19 2006-06-13 Isotechnika, Inc. Cyclosporin analog formulations
US20030113366A1 (en) * 2001-12-14 2003-06-19 Macgregor Alexander Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents
US6858666B2 (en) * 2002-03-04 2005-02-22 Aveka, Inc. Organogel particles
US20040018237A1 (en) * 2002-05-31 2004-01-29 Perricone Nicholas V. Topical drug delivery using phosphatidylcholine
US8642079B2 (en) 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
US20050232974A1 (en) * 2004-04-19 2005-10-20 Gore Makarand P System and a method for pharmaceutical dosage preparation using jettable microemulsions
US8758821B2 (en) 2004-05-04 2014-06-24 Hormos Medical Ltd. Oral formulations of ospemifene
CA2565134C (en) 2004-05-04 2013-05-21 Veli-Matti Lehtola Novel oral formulations of ospemifene
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
GB2464393B (en) * 2006-11-29 2011-05-18 Malvern Cosmeceutics Ltd Solubilised peptide or protein formulations using molecular assemblies comprising a surfactant and a lipid
GB0623838D0 (en) * 2006-11-29 2007-01-10 Malvern Cosmeceutics Ltd Novel compositions
US7504530B2 (en) 2007-02-14 2009-03-17 Hormos Medical Ltd. Methods for the preparation of fispemifene from ospemifene
JP5363344B2 (ja) 2007-02-14 2013-12-11 ホルモス メディカル リミテッド 治療に有用なトリフェニルブテン誘導体の調製方法
FR2917976B1 (fr) * 2007-06-29 2010-05-28 Galderma Sa Composition dermatologique comprenant des vehicules lipidiques de calcitriol, son procede de preparation et son utilisation
WO2010036947A2 (en) * 2008-09-27 2010-04-01 Jina Pharmaceuticals, Inc. Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof
WO2011143566A1 (en) * 2010-05-14 2011-11-17 Archer Daniels Midland Company Food compositions comprising organogels
JP6073552B2 (ja) * 2008-11-14 2017-02-01 アーチャー−ダニエルズ−ミッドランド カンパニー オルガノゲル組成物及び製造方法
WO2014060639A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene
CA2889422A1 (en) * 2012-10-26 2014-05-01 Schlumberger Canada Limited Compositions and methods for completing subterranean wells
WO2015164657A1 (en) * 2014-04-23 2015-10-29 Bcs Business Consulting Services Pte Ltd Incorporation of water soluble component(s) into anhydrous formulations
WO2016128235A1 (en) * 2015-02-11 2016-08-18 Nestec S.A. Vitamin a composition
CN106963725A (zh) * 2017-04-19 2017-07-21 赵艳霞 一种地塞米松纳米凝胶及其制备方法
CN110636863A (zh) 2017-05-18 2019-12-31 丘比株式会社 具有自乳化性的组合物及其制造方法及纳米乳液及其制造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT370721B (de) * 1981-02-24 1983-04-25 Ciba Geigy Ag Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der
CH662944A5 (it) * 1984-10-18 1987-11-13 Pier Luigi Prof Dr Luisi Procedimento per la preparazione di biocompatibili di micelle inverse di biocompatibili e loro utilizzazione.
US5294249A (en) * 1987-03-27 1994-03-15 Luisi Pier L Blendpolymers
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
US5206219A (en) * 1991-11-25 1993-04-27 Applied Analytical Industries, Inc. Oral compositions of proteinaceous medicaments

Also Published As

Publication number Publication date
PT760651E (pt) 2001-11-30
DE69521611D1 (de) 2001-08-09
DK0760651T3 (da) 2001-10-22
DE69521611T2 (de) 2001-10-18
CA2190869A1 (en) 1995-11-30
US6004580A (en) 1999-12-21
FI942387A0 (fi) 1994-05-24
EP0760651B1 (en) 2001-07-04
FI100692B (fi) 1998-02-13
EP0760651A1 (en) 1997-03-12
ATE202699T1 (de) 2001-07-15
WO1995031969A1 (en) 1995-11-30
JPH10500675A (ja) 1998-01-20
FI942387L (fi) 1995-11-25
GR3036681T3 (en) 2001-12-31
AU2309195A (en) 1995-12-18

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