ES2159624T3 - Toxinas botulinicas para el tratamiento de la hiperhidrosis. - Google Patents
Toxinas botulinicas para el tratamiento de la hiperhidrosis.Info
- Publication number
- ES2159624T3 ES2159624T3 ES95906674T ES95906674T ES2159624T3 ES 2159624 T3 ES2159624 T3 ES 2159624T3 ES 95906674 T ES95906674 T ES 95906674T ES 95906674 T ES95906674 T ES 95906674T ES 2159624 T3 ES2159624 T3 ES 2159624T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- botulinic
- hyperhydrosis
- toxins
- botulinum toxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003053 toxin Substances 0.000 title 1
- 231100000765 toxin Toxicity 0.000 title 1
- 108700012359 toxins Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 4
- 108030001720 Bontoxilysin Proteins 0.000 abstract 2
- 229940053031 botulinum toxin Drugs 0.000 abstract 2
- 208000007101 Muscle Cramp Diseases 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 210000005095 gastrointestinal system Anatomy 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 230000035900 sweating Effects 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
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- A—HUMAN NECESSITIES
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-
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A61P25/08—Antiepileptics; Anticonvulsants
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Otolaryngology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA INVENCION SUMINISTRA UN METODO PARA ALIVIAR EL DOLOR ASOCIADO CON CONTRACCIONES MUSCULARES, UN COMPUESTO Y UN METODO DE TRATAMIENTO DE CONDICIONES TALES COMO LAS SECRECIONES COLINERGICAS, CONTROLADAS QUE INCLUYEN LA SUDORACION EXCESIVA, LAS SECRECIONES LACRIMALES Y MUCOSALES Y UN METODO PARA EL TRATAMIENTO DE ENFERMEDADES DE LOS MUSCULOS LISOS QUE INCLUYEN, PERO QUE NO ESTAN LIMITADAS, LOS ESPASMOS DEL ESFINTER DE LA ARTERIOLA CARDIOVASCULAR, DEL SISTEMA GASTROINTESTINAL, DEL SISTEMA URINARIO, DE LA VEJIGA Y DEL RECTO, EL METODO COMPRENDE LA ADMINISTRACION AL PACIENTE QUE SUFRA DE TALES DESORDENES DE UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE TOXINA DE BOTULINUM SELECCIONADA DE ENTRE EL GRUPO QUE CONSTA DE TOXINA DE BOTULINUM DE LOS TIPOS B, C, D, E, F Y G.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17399693A | 1993-12-28 | 1993-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2159624T3 true ES2159624T3 (es) | 2001-10-16 |
Family
ID=22634387
Family Applications (18)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97200028T Expired - Lifetime ES2163090T3 (es) | 1993-12-28 | 1994-12-16 | Uso de toxina botulinica para tratar la cefalea tensional. |
| ES99203920T Expired - Lifetime ES2207910T5 (es) | 1993-12-28 | 1994-12-16 | Toxinas botulinicas para modular las secreciones controladas por el sistema colinergico. |
| ES05018368T Expired - Lifetime ES2334357T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de toxinas botulinicas para el tratamiento de un musculo espastico. |
| ES07002714T Expired - Lifetime ES2309973T3 (es) | 1993-12-28 | 1994-12-16 | Uso de toxina botulinica para la fabricacion de un medicamento para reducir el dolor en la parte baja de la espalda. |
| ES04019047T Expired - Lifetime ES2247575T3 (es) | 1993-12-28 | 1994-12-16 | Componente neurotoxico de la toxina botulinica para modular las secreciones controladas por el sistema colinergico. |
| ES03015589T Expired - Lifetime ES2242126T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de la toxina botulinica para tratar el dolor asociado a la musculatura. |
| ES03015590T Expired - Lifetime ES2251651T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de la toxina botulinica para tratar los espasmos musculares. |
| ES01118793T Expired - Lifetime ES2355491T3 (es) | 1993-12-28 | 1994-12-16 | Uso de toxinabotulínica tipo b para la fabricación de un medicamento para el tratamiento de espasmos musculares. |
| ES05016177T Expired - Lifetime ES2340172T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de la toxina botulinica para tratar el dolor asociado con la distonia cervical. |
| ES99203735T Expired - Lifetime ES2237033T5 (es) | 1993-12-28 | 1994-12-16 | Toxinas botulinicas a para tratar dolor asociado con espasmos de los musculos lisos. |
| ES00203421T Expired - Lifetime ES2223393T3 (es) | 1993-12-28 | 1994-12-16 | Toxinas botulinicas para tratar dolor asociado con transtornos musculares. |
| ES01118792T Expired - Lifetime ES2319860T3 (es) | 1993-12-28 | 1994-12-16 | Uso de toxina botulinica de tipo b para la fabricacion de un medicamento para reducir el dolor asociado a un trastorno muscular. |
| ES05018367T Expired - Lifetime ES2339865T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de toxinas botulinicas para el tratamiento de musculos espasticos. |
| ES00203294T Expired - Lifetime ES2246800T3 (es) | 1993-12-28 | 1994-12-16 | Toxina botulinica para tratar la distonia. |
| ES95906674T Expired - Lifetime ES2159624T3 (es) | 1993-12-28 | 1994-12-16 | Toxinas botulinicas para el tratamiento de la hiperhidrosis. |
| ES08017803T Expired - Lifetime ES2347384T3 (es) | 1993-12-28 | 1994-12-16 | Componente neurotoxico de una toxina botulinica para tratar de discinesia tardia. |
| ES04019048T Expired - Lifetime ES2248780T3 (es) | 1993-12-28 | 1994-12-16 | Componente neurotoxico de toxinas botulinicas para tratar la distonia cervical. |
| ES04019046T Expired - Lifetime ES2332905T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de la toxina botulinica para el tratamiento de trastornos de musculos lisos. |
Family Applications Before (14)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97200028T Expired - Lifetime ES2163090T3 (es) | 1993-12-28 | 1994-12-16 | Uso de toxina botulinica para tratar la cefalea tensional. |
| ES99203920T Expired - Lifetime ES2207910T5 (es) | 1993-12-28 | 1994-12-16 | Toxinas botulinicas para modular las secreciones controladas por el sistema colinergico. |
| ES05018368T Expired - Lifetime ES2334357T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de toxinas botulinicas para el tratamiento de un musculo espastico. |
| ES07002714T Expired - Lifetime ES2309973T3 (es) | 1993-12-28 | 1994-12-16 | Uso de toxina botulinica para la fabricacion de un medicamento para reducir el dolor en la parte baja de la espalda. |
| ES04019047T Expired - Lifetime ES2247575T3 (es) | 1993-12-28 | 1994-12-16 | Componente neurotoxico de la toxina botulinica para modular las secreciones controladas por el sistema colinergico. |
| ES03015589T Expired - Lifetime ES2242126T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de la toxina botulinica para tratar el dolor asociado a la musculatura. |
| ES03015590T Expired - Lifetime ES2251651T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de la toxina botulinica para tratar los espasmos musculares. |
| ES01118793T Expired - Lifetime ES2355491T3 (es) | 1993-12-28 | 1994-12-16 | Uso de toxinabotulínica tipo b para la fabricación de un medicamento para el tratamiento de espasmos musculares. |
| ES05016177T Expired - Lifetime ES2340172T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de la toxina botulinica para tratar el dolor asociado con la distonia cervical. |
| ES99203735T Expired - Lifetime ES2237033T5 (es) | 1993-12-28 | 1994-12-16 | Toxinas botulinicas a para tratar dolor asociado con espasmos de los musculos lisos. |
| ES00203421T Expired - Lifetime ES2223393T3 (es) | 1993-12-28 | 1994-12-16 | Toxinas botulinicas para tratar dolor asociado con transtornos musculares. |
| ES01118792T Expired - Lifetime ES2319860T3 (es) | 1993-12-28 | 1994-12-16 | Uso de toxina botulinica de tipo b para la fabricacion de un medicamento para reducir el dolor asociado a un trastorno muscular. |
| ES05018367T Expired - Lifetime ES2339865T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de toxinas botulinicas para el tratamiento de musculos espasticos. |
| ES00203294T Expired - Lifetime ES2246800T3 (es) | 1993-12-28 | 1994-12-16 | Toxina botulinica para tratar la distonia. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08017803T Expired - Lifetime ES2347384T3 (es) | 1993-12-28 | 1994-12-16 | Componente neurotoxico de una toxina botulinica para tratar de discinesia tardia. |
| ES04019048T Expired - Lifetime ES2248780T3 (es) | 1993-12-28 | 1994-12-16 | Componente neurotoxico de toxinas botulinicas para tratar la distonia cervical. |
| ES04019046T Expired - Lifetime ES2332905T3 (es) | 1993-12-28 | 1994-12-16 | Uso del componente neurotoxico de la toxina botulinica para el tratamiento de trastornos de musculos lisos. |
Country Status (8)
| Country | Link |
|---|---|
| EP (23) | EP1790352B1 (es) |
| JP (33) | JP3238154B2 (es) |
| AU (1) | AU688452B2 (es) |
| CA (2) | CA2682117A1 (es) |
| DE (23) | DE69435194D1 (es) |
| ES (18) | ES2163090T3 (es) |
| FR (1) | FR08C0034I1 (es) |
| WO (1) | WO1995017904A2 (es) |
Families Citing this family (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9120306D0 (en) | 1991-09-24 | 1991-11-06 | Graham Herbert K | Method and compositions for the treatment of cerebral palsy |
| DE69435254D1 (de) | 1993-06-10 | 2009-12-31 | Allergan Inc | Behandlung von neuromusculaeren Störungen und Zuständen mit verschiedenen botulism Serotypen |
| AU2007202480B2 (en) * | 1993-12-28 | 2009-01-29 | Allergan, Inc. | Method for treating pain associated with a muscle disorder |
| US8187612B2 (en) | 1993-12-28 | 2012-05-29 | Allergan, Inc. | Use of the neurotoxic component of a botulinum toxin for treating a spastic muscle |
| EP1790352B1 (en) * | 1993-12-28 | 2008-07-09 | Allergan, Inc. | Use of botulinum toxin for the manufacture of a medicament for reducing low back pain |
| US8557256B2 (en) | 1993-12-28 | 2013-10-15 | Allergan, Inc. | Treatment for cervical dystonia with the neurotoxic component of a botulinum toxin |
| US6974578B1 (en) * | 1993-12-28 | 2005-12-13 | Allergan, Inc. | Method for treating secretions and glands using botulinum toxin |
| PT1086702E (pt) * | 1994-05-09 | 2005-08-31 | William J Binder | Neurotoxinas pre-sinapticas para tratamento da dor de cabeca devida a enxaqueca |
| US5721215A (en) * | 1996-03-20 | 1998-02-24 | Allergan | Injectable therapy for control of muscle spasms and pain related to muscle spasms |
| US6699966B1 (en) | 1996-07-08 | 2004-03-02 | University Of Massachusetts | Proteins within the type E botulinum neurotoxin complex |
| US6780413B2 (en) | 1996-09-19 | 2004-08-24 | The United States Of America As Represented By The Department Of Health And Human Services | Immunotoxin (mAB-RICIN) for the treatment of focal movement disorders |
| AU2006225231B2 (en) * | 1997-07-15 | 2006-12-07 | The Regents Of The University Of Colorado | Use of neurotoxin therapy for treatment of urologic and related disorders |
| US7449192B2 (en) | 1997-07-15 | 2008-11-11 | The Regents Of The University Of Colorado | Use of neurotoxin therapy for treatment of urologic and related disorders related to neurogenic bladder dysfunction |
| US7470431B2 (en) | 1997-07-15 | 2008-12-30 | The Regents Of The University Of Colorado | Use of neurotoxin therapy for treatment of urological-neurological disorders associated with prostate cancer |
| AU2008201535C1 (en) * | 1997-07-15 | 2013-09-12 | Allergan, Inc. | Use of neurotoxin therapy for treatment of urologic and related disorders |
| US7455845B2 (en) | 1997-07-15 | 2008-11-25 | The Regents Of The University Of Colorado | Use of neurotoxin therapy for treatment of urologic and related disorders related to lowering elevated bladder pressure |
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2008
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