ES2155048T1 - Composicion biologicamente activa. - Google Patents
Composicion biologicamente activa.Info
- Publication number
- ES2155048T1 ES2155048T1 ES99927061T ES99927061T ES2155048T1 ES 2155048 T1 ES2155048 T1 ES 2155048T1 ES 99927061 T ES99927061 T ES 99927061T ES 99927061 T ES99927061 T ES 99927061T ES 2155048 T1 ES2155048 T1 ES 2155048T1
- Authority
- ES
- Spain
- Prior art keywords
- biologically active
- ester
- polyester
- active agent
- carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 150000002148 esters Chemical class 0.000 abstract 4
- 229920000728 polyester Polymers 0.000 abstract 4
- 239000013543 active substance Substances 0.000 abstract 3
- 239000007788 liquid Substances 0.000 abstract 3
- 239000011159 matrix material Substances 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 239000006185 dispersion Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Un método para la preparación de una composición biológicamente activa que comprende un agente biológicamente activo disuelto y/o dispersado en un portador no cristalino de éster y/o poliéster para el mismo, en donde una sustancia portadora de partida, o una mezcla de dos o más sustancias portadoras de partida diferentes, se somete(n) a una(s) reacción(es) química(s) tal(es) que se forme una matriz portadora liquida no cristalina de éster y/o poliéster; se añade un agente biológicamente activo, en forma sólida y/o líquida o alternativamente en forma de una solución o dispersión, a dicha matriz portadora líquida no cristalina después de que se haya(n) completado dicha(s) reacción(es) formadora(s) de éster y/o poliéster; y el agente biológicamente activo se disuelve a continuación en dicha matriz de éster y/o poliéster a una temperatura por encima de la temperatura ambiente de modo que proporcione una composición sobresaturada a temperatura ambiente.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9801704A SE9801704D0 (sv) | 1998-05-14 | 1998-05-14 | Biologically active composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2155048T1 true ES2155048T1 (es) | 2001-05-01 |
| ES2155048T3 ES2155048T3 (es) | 2006-06-16 |
Family
ID=20411318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99927061T Expired - Lifetime ES2155048T3 (es) | 1998-05-14 | 1999-05-12 | Composicion biologicamente activa. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6537576B1 (es) |
| EP (1) | EP1082102B1 (es) |
| JP (1) | JP2002514587A (es) |
| KR (1) | KR100592971B1 (es) |
| CN (1) | CN1309553A (es) |
| AT (1) | ATE310500T1 (es) |
| AU (1) | AU736480B2 (es) |
| CA (1) | CA2331527C (es) |
| DE (2) | DE1082102T1 (es) |
| ES (1) | ES2155048T3 (es) |
| GR (1) | GR20010300013T1 (es) |
| HU (1) | HUP0102426A2 (es) |
| IL (2) | IL139576A0 (es) |
| NO (1) | NO20005724L (es) |
| NZ (1) | NZ508073A (es) |
| PL (1) | PL344051A1 (es) |
| SE (1) | SE9801704D0 (es) |
| TR (1) | TR200003589T2 (es) |
| WO (1) | WO1999058108A1 (es) |
| ZA (1) | ZA200006474B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003524652A (ja) * | 2000-02-29 | 2003-08-19 | ツァン,ツィエ | 改良された経皮薬剤パッチ |
| MX2008015599A (es) * | 2006-06-14 | 2009-03-06 | Reddys Lab Ltd Dr | Composiciones topicas. |
| US20080226698A1 (en) | 2007-03-16 | 2008-09-18 | Mylan Technologies, Inc. | Amorphous drug transdermal systems, manufacturing methods, and stabilization |
| CA2739380C (en) * | 2008-10-06 | 2014-12-09 | Mylan Technologies, Inc. | Amorphous rotigotine transdermal system |
| US8558008B2 (en) | 2013-02-28 | 2013-10-15 | Dermira, Inc. | Crystalline glycopyrrolate tosylate |
| US9006462B2 (en) | 2013-02-28 | 2015-04-14 | Dermira, Inc. | Glycopyrrolate salts |
| ES2981043T3 (es) | 2013-02-28 | 2024-10-07 | Journey Medical Corp | Procedimiento para fabricar tosilato de glicopirrolato treo |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD217989A1 (de) | 1983-08-09 | 1985-01-30 | Univ Ernst Moritz Arndt | Verfahren zur herstellung einer pharmazeutischen zubereitung |
| US4940701A (en) | 1984-01-25 | 1990-07-10 | Beecham Group P.L.C. | Topical drug release system |
| AR246186A1 (es) | 1989-11-17 | 1994-07-29 | Beta Pharm Co | Procedimiento para fabricar un dispositivo para administrar estradiol por via transdermica. |
| SE9502244D0 (sv) * | 1995-06-20 | 1995-06-20 | Bioglan Ab | A composition and a process for the preparation thereof |
| US5906830A (en) * | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
| GB2306885B (en) | 1995-11-08 | 1999-07-14 | Reckitt & Colmann Prod Ltd | Supersaturated Pharmaceutical Compositions |
-
1998
- 1998-05-14 SE SE9801704A patent/SE9801704D0/xx unknown
-
1999
- 1999-05-12 AU AU44050/99A patent/AU736480B2/en not_active Ceased
- 1999-05-12 CA CA2331527A patent/CA2331527C/en not_active Expired - Fee Related
- 1999-05-12 IL IL13957699A patent/IL139576A0/xx active IP Right Grant
- 1999-05-12 CN CN99808547A patent/CN1309553A/zh active Pending
- 1999-05-12 NZ NZ508073A patent/NZ508073A/xx not_active IP Right Cessation
- 1999-05-12 TR TR2000/03589T patent/TR200003589T2/xx unknown
- 1999-05-12 DE DE1082102T patent/DE1082102T1/de active Pending
- 1999-05-12 HU HU0102426A patent/HUP0102426A2/hu unknown
- 1999-05-12 EP EP99927061A patent/EP1082102B1/en not_active Expired - Lifetime
- 1999-05-12 PL PL99344051A patent/PL344051A1/xx unknown
- 1999-05-12 WO PCT/SE1999/000823 patent/WO1999058108A1/en not_active Ceased
- 1999-05-12 DE DE69928524T patent/DE69928524T2/de not_active Expired - Lifetime
- 1999-05-12 AT AT99927061T patent/ATE310500T1/de not_active IP Right Cessation
- 1999-05-12 ES ES99927061T patent/ES2155048T3/es not_active Expired - Lifetime
- 1999-05-12 JP JP2000547960A patent/JP2002514587A/ja active Pending
- 1999-05-12 US US09/700,176 patent/US6537576B1/en not_active Expired - Lifetime
- 1999-05-12 KR KR1020007012708A patent/KR100592971B1/ko not_active Expired - Fee Related
-
2000
- 2000-11-09 IL IL139576A patent/IL139576A/en not_active IP Right Cessation
- 2000-11-09 ZA ZA200006474A patent/ZA200006474B/xx unknown
- 2000-11-13 NO NO20005724A patent/NO20005724L/no not_active Application Discontinuation
-
2001
- 2001-04-30 GR GR20010300013T patent/GR20010300013T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE310500T1 (de) | 2005-12-15 |
| NZ508073A (en) | 2002-12-20 |
| DE1082102T1 (de) | 2001-09-06 |
| NO20005724D0 (no) | 2000-11-13 |
| GR20010300013T1 (en) | 2001-04-30 |
| WO1999058108A1 (en) | 1999-11-18 |
| ZA200006474B (en) | 2001-09-04 |
| DE69928524D1 (de) | 2005-12-29 |
| EP1082102B1 (en) | 2005-11-23 |
| IL139576A (en) | 2007-07-04 |
| AU4405099A (en) | 1999-11-29 |
| SE9801704D0 (sv) | 1998-05-14 |
| HUP0102426A2 (hu) | 2002-03-28 |
| PL344051A1 (en) | 2001-09-24 |
| CN1309553A (zh) | 2001-08-22 |
| IL139576A0 (en) | 2002-02-10 |
| ES2155048T3 (es) | 2006-06-16 |
| DE69928524T2 (de) | 2006-08-10 |
| EP1082102A1 (en) | 2001-03-14 |
| JP2002514587A (ja) | 2002-05-21 |
| KR20010052348A (ko) | 2001-06-25 |
| KR100592971B1 (ko) | 2006-06-23 |
| AU736480B2 (en) | 2001-07-26 |
| TR200003589T2 (tr) | 2001-03-21 |
| NO20005724L (no) | 2001-01-09 |
| CA2331527C (en) | 2010-04-13 |
| US6537576B1 (en) | 2003-03-25 |
| CA2331527A1 (en) | 1999-11-18 |
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