[go: up one dir, main page]

ES2151382B1 - RECOMBINANT DNA CODING FOR HEVEA BRASILIENSIS PROFILINE ALLERGY EPITOPES USEFUL FOR DIAGNOSIS AND LATEX ALLERGY TREATMENT. - Google Patents

RECOMBINANT DNA CODING FOR HEVEA BRASILIENSIS PROFILINE ALLERGY EPITOPES USEFUL FOR DIAGNOSIS AND LATEX ALLERGY TREATMENT.

Info

Publication number
ES2151382B1
ES2151382B1 ES9800536A ES9800536A ES2151382B1 ES 2151382 B1 ES2151382 B1 ES 2151382B1 ES 9800536 A ES9800536 A ES 9800536A ES 9800536 A ES9800536 A ES 9800536A ES 2151382 B1 ES2151382 B1 ES 2151382B1
Authority
ES
Spain
Prior art keywords
allergy
diagnosis
hevea brasiliensis
recombinant dna
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9800536A
Other languages
Spanish (es)
Other versions
ES2151382A1 (en
Inventor
Pelaez Ricardo Palacios
Quesada Jorge Martinez
Garate Alberto Martinez
Ortega Juan Andres Asturias
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roxall Medicina Espana SA
Original Assignee
Bial Industrial Farmaceutica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bial Industrial Farmaceutica SA filed Critical Bial Industrial Farmaceutica SA
Priority to ES9800536A priority Critical patent/ES2151382B1/en
Publication of ES2151382A1 publication Critical patent/ES2151382A1/en
Application granted granted Critical
Publication of ES2151382B1 publication Critical patent/ES2151382B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

ADN recombinante que codifica para epitopos del alergeno profilina de Hevea brasiliensis útil para el diagnóstico y tratamiento de alergia a látex. La molécula de ADN recombinante tiene un fragmento de 396 nucleótidos de ADNc proveniente de ARNm de Hevea brasiliensis. Esta molécula codifica una molécula polipeptídica que contiene al menos un epítopo del alergeno profilina de la planta del látex (Hevea brasiliensis). El polipéptido puede obtenerse por cultivo de un organismo hospedador que contiene un vehículo de expresión microbiano que se autorreplica en dicho organismo y sirve para expresar la molécula de ADN. Estas moléculas recombinantes tienen aplicación en el diagnóstico y tratamiento de alergias, así como en la producción de vacunas.Recombinant DNA encoding Hevea brasiliensis profilin allergen epitopes useful for the diagnosis and treatment of latex allergy. The recombinant DNA molecule has a 396 nucleotide fragment of cDNA from Hevea brasiliensis mRNA. This molecule encodes a polypeptide molecule that contains at least one epitope of the latex plant profilin allergen (Hevea brasiliensis). The polypeptide can be obtained by culturing a host organism that contains a microbial expression vehicle that self-replicates in said organism and serves to express the DNA molecule. These recombinant molecules have application in the diagnosis and treatment of allergies, as well as in the production of vaccines.

ES9800536A 1998-03-12 1998-03-12 RECOMBINANT DNA CODING FOR HEVEA BRASILIENSIS PROFILINE ALLERGY EPITOPES USEFUL FOR DIAGNOSIS AND LATEX ALLERGY TREATMENT. Expired - Fee Related ES2151382B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9800536A ES2151382B1 (en) 1998-03-12 1998-03-12 RECOMBINANT DNA CODING FOR HEVEA BRASILIENSIS PROFILINE ALLERGY EPITOPES USEFUL FOR DIAGNOSIS AND LATEX ALLERGY TREATMENT.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9800536A ES2151382B1 (en) 1998-03-12 1998-03-12 RECOMBINANT DNA CODING FOR HEVEA BRASILIENSIS PROFILINE ALLERGY EPITOPES USEFUL FOR DIAGNOSIS AND LATEX ALLERGY TREATMENT.

Publications (2)

Publication Number Publication Date
ES2151382A1 ES2151382A1 (en) 2000-12-16
ES2151382B1 true ES2151382B1 (en) 2001-07-01

Family

ID=8303096

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9800536A Expired - Fee Related ES2151382B1 (en) 1998-03-12 1998-03-12 RECOMBINANT DNA CODING FOR HEVEA BRASILIENSIS PROFILINE ALLERGY EPITOPES USEFUL FOR DIAGNOSIS AND LATEX ALLERGY TREATMENT.

Country Status (1)

Country Link
ES (1) ES2151382B1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69535173T2 (en) * 1994-09-16 2007-08-23 The Board Of The Rubber Research Institute Of Malaysia Allergy-inducing proteins from natural rubber latex, their production and application in detection methods

Also Published As

Publication number Publication date
ES2151382A1 (en) 2000-12-16

Similar Documents

Publication Publication Date Title
ATE510011T1 (en) NEW FUNGAL PROTEINS AND THE NUCLEIC ACIDS THAT ENCOD THEM
BR0011499A (en) Nucleic acid molecules from plants and transgenic wheat plant cells and their use for the production of modified starch
MX353906B (en) METHOD FOR THE PRODUCTION OF POLY-INSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS.
AR083740A1 (en) DKK1 ANTIBODIES (DICKKOPF-1) AND METHODS OF USE
EP2363460A3 (en) Acid fungal proteases
AR026808A1 (en) MOLECULES OF NUCLEIC ACIDS AND OTHER MOLECULES ASSOCIATED WITH THE RESISTANCE TO CHEMICAL NEMATODE IN SOYA
CL2008001634A1 (en) Isolated anti-notch1 negative regulatory region antibody; polynucleotide that encodes it; vector and host cell; Method of production; composition comprising it; and its use to prepare a medicament for treating a disorder associated with an increase in the signaling or expression of notch1 in an individual.
EA201101553A1 (en) POLYPEPTID, DEGRADING CARBOHYDRATES AND ITS APPLICATIONS
PT1385950E (en) Computer-directed assembly of a polynucleotide encoding a target polypeptide
AR107463A1 (en) BACILLUS THURINGIENSIS GENE WITH ACTIVITY AGAINST THE LEPIDOPTER ORDER
UA98620C2 (en) Attenuated classic swine fever virus containing modified glycoprotein e2
ATE513043T1 (en) CHAPERONE-LIKE OLIGOMERIC PROTEINS STABLE TO DENATURING AGENT AND/OR PROTEASER-RESISTANT, THESE ENCODING POLYNUCLEOTIDES AND USES THEREOF
ATE473238T1 (en) TUBERCULOSIS VACCINE WITH IMPROVED EFFICIENCY
AR108284A1 (en) INSECTICIDE COMBINATIONS OF POLYPEPTIDES THAT HAVE ENHANCED SPECTRUM OF ACTIVITY AND USES OF THESE
MA42902A (en) MARINAL-INFILTRATING LYMPHOCYTES (MIL) AS A SOURCE OF T-LYMPHOCYTES FOR CHEMERIC ANTIGEN RECEPTOR (CAR) THERAPY
DK1290160T3 (en) Human Pellino polypeptides
ES2151382B1 (en) RECOMBINANT DNA CODING FOR HEVEA BRASILIENSIS PROFILINE ALLERGY EPITOPES USEFUL FOR DIAGNOSIS AND LATEX ALLERGY TREATMENT.
ATE497007T1 (en) POLYNUCLEOTIDES CODING FOR PRENYL PROTEASES FROM PLANT
WO2002018576A3 (en) Compositions and methods relating to lung specific genes
DE50108009D1 (en) NUCLEIN SUCTION MOLEKUL COMPRISING ONE SDF-1 GAMMA CHEMOKIN, A NEUROPEPTID PRACTICE OR AT LEAST ONE NEUROPEPTIDE ENCODING NUCLEAR ACID SEQUENCE
AR070607A1 (en) METHODS AND COMPOSITIONS FOR PEST CONTROL IN PLANTS
MXPA05011716A (en) Canine ghrh gene, polypeptides and methods of use.
WO2023023589A3 (en) Mrna vaccines against tick salivary proteins, and methods of using same
ATE520710T1 (en) POLYPEPTIDES OF LEISHMANIA MAJOR AND POLYNUCLEOTIDES CODING THEREFOR, AND THEIR APPLICATIONS AS VACCINES, THERAPEUTICS AND DIAGNOSTICS
EP4424702A4 (en) NAD+ protein probe for complete genetic coding based on resonance energy transfer, as well as manufacturing methods and uses thereof.

Legal Events

Date Code Title Description
PC2A Transfer of patent
EC2A Search report published

Date of ref document: 20001216

Kind code of ref document: A1

Effective date: 20001216

FD2A Announcement of lapse in spain

Effective date: 20161214