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ES2150487T3 - Tapon escleral biodegradable. - Google Patents

Tapon escleral biodegradable.

Info

Publication number
ES2150487T3
ES2150487T3 ES94907661T ES94907661T ES2150487T3 ES 2150487 T3 ES2150487 T3 ES 2150487T3 ES 94907661 T ES94907661 T ES 94907661T ES 94907661 T ES94907661 T ES 94907661T ES 2150487 T3 ES2150487 T3 ES 2150487T3
Authority
ES
Spain
Prior art keywords
drug
surgical operation
shutter
vitreous
vitreous body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94907661T
Other languages
English (en)
Inventor
Yuichiro Ogura
Yoshito Ikada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2150487T3 publication Critical patent/ES2150487T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UN OBTURADOR ESCLEROTICO QUE CONSTA DE UN LACTOCOPOLIMERO, A UN OBTURADOR ESCLEROTICO QUE CONTIENE UNA DROGA Y QUE ESTA DISEÑADO DE MANERA QUE LIBERE LA DROGA GRADUALMENTE A INTERIOR DEL CUERPO VITREO, Y A UN OBTURADOR ESCLEROTICO UTILIZADO PARA CURAR O EVITAR UNA ENFERMEDAD RETINAL UTILIZANDO LA ACCION DE LA LIBERACION SOSTENIDA DE LA DROGA Y QUE PROMUEVA LA CURACION DEL CUERPO VITREO DESPUES DE UNA OPERACION QUIRURGICA SOBRE EL MISMO. EL OBTURADOR ESCLEROTICO DE ACUERDO CON LA INVENCION CIERRA DE FORMA EFECTIVA UNA ABERTURA HECHA DURANTE UNA OPERACION QUIRURGICA SOBRE EL CUERPO VITREO, Y QUE NO NECESITE SER ELIMINADO DESPUES DE LA OPERACION QUIRURGICA. CUANDO SE UTILIZA ESTE OBTURADOR ESCLEROTICO, UNA DROGA PUEDE LIBERARSE GRADUALMENTE DURANTE UN LARGO PERIODO DE TIEMPO EN EL INTERIOR DEL TEJIDO INTRAOCULAR DENTRO DEL CUAL LA PERMEABILIDAD DE LA DROGA SERIA DE OTRA MANERA MUY DIFICULTOSA, DE MANERA QUE LA ADMINISTRACION DE UNA DROGA PUEDA LLEVARSE A CABO DE FORMASEGURA Y EFECTIVA. MAS AUN, PUEDE ENCONTRARSE UN METODO DE ADMINISTRACION SIMPLE Y CLINICAMENTE APLICABLE UTILIZANDO UN CORTE ESCLEROTICO HECHO DURANTE UNA OPERACION QUIRURGICA SOBRE UN CUERPO VITREO.
ES94907661T 1993-02-26 1994-02-23 Tapon escleral biodegradable. Expired - Lifetime ES2150487T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6281493 1993-02-26
JP6945793 1993-03-04

Publications (1)

Publication Number Publication Date
ES2150487T3 true ES2150487T3 (es) 2000-12-01

Family

ID=26403867

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94907661T Expired - Lifetime ES2150487T3 (es) 1993-02-26 1994-02-23 Tapon escleral biodegradable.

Country Status (12)

Country Link
EP (1) EP0654256B1 (es)
KR (1) KR100313268B1 (es)
AT (1) ATE195065T1 (es)
CA (1) CA2118515A1 (es)
DE (1) DE69425411T2 (es)
DK (1) DK0654256T3 (es)
ES (1) ES2150487T3 (es)
FI (1) FI945014L (es)
GR (1) GR3034526T3 (es)
NO (1) NO303665B1 (es)
PT (1) PT654256E (es)
WO (1) WO1994018921A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999001156A1 (en) 1997-07-02 1999-01-14 Santen Pharmaceutical Co., Ltd. Polylactic acid scleral plugs
US6991650B2 (en) 1997-10-08 2006-01-31 Refocus Ocular, Inc. Scleral expansion device having duck bill
US7008396B1 (en) 1999-09-03 2006-03-07 Restorvision, Inc. Ophthalmic device and method of manufacture and use
US6375642B1 (en) * 2000-02-15 2002-04-23 Grieshaber & Co. Ag Schaffhausen Method of and device for improving a drainage of aqueous humor within the eye
EP1637126B1 (en) * 2000-07-05 2016-12-14 Allergan, Inc. Methods for treating inflammation of the eye
US6726918B1 (en) 2000-07-05 2004-04-27 Oculex Pharmaceuticals, Inc. Methods for treating inflammation-mediated conditions of the eye
WO2002043785A2 (en) 2000-11-29 2002-06-06 Oculex Pharmaceuticals, Inc. Intraocular implants for preventing transplant rejection in the eye
US20050048099A1 (en) 2003-01-09 2005-03-03 Allergan, Inc. Ocular implant made by a double extrusion process
US20040137059A1 (en) 2003-01-09 2004-07-15 Thierry Nivaggioli Biodegradable ocular implant
SG149004A1 (en) 2003-12-05 2009-01-29 Bristol Myers Squibb Co Inhibitors of type 2 vascular endothelial growth factor receptors
US8685435B2 (en) 2004-04-30 2014-04-01 Allergan, Inc. Extended release biodegradable ocular implants
US8802128B2 (en) 2006-06-23 2014-08-12 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
WO2008008366A2 (en) 2006-07-11 2008-01-17 Refocus Group, Inc. Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods
US8911496B2 (en) 2006-07-11 2014-12-16 Refocus Group, Inc. Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods
JP5537946B2 (ja) 2006-11-22 2014-07-02 ブリストル−マイヤーズ スクイブ カンパニー Ｉｇｆ−ｉｒを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬
US8969415B2 (en) 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
US8231892B2 (en) 2007-05-24 2012-07-31 Allergan, Inc. Biodegradable drug delivery system
AU2009213141A1 (en) 2008-02-14 2009-08-20 Bristol-Myers Squibb Company Targeted therapeutics based on engineered proteins that bind EGFR
PE20091931A1 (es) 2008-05-22 2009-12-31 Bristol Myers Squibb Co Proteinas de dominio de armazon basadas en fibronectina multivalentes
TWI496582B (zh) 2008-11-24 2015-08-21 必治妥美雅史谷比公司 雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子
ES2573108T3 (es) 2010-05-26 2016-06-06 Bristol-Myers Squibb Company Proteínas de armazón a base de fibronectina que tienen estabilidad mejorada
KR101750651B1 (ko) * 2016-01-28 2017-06-23 동국대학교 산학협력단 약물 잔류 방지능 및 재충전 기능을 갖는 안구 내 약물 주입 장치
CN106667656A (zh) * 2016-06-30 2017-05-17 广州聚明生物科技有限公司 生物可降解泪道栓及其制备方法和应用
EP3518828B1 (en) * 2016-10-03 2024-12-04 California Institute of Technology Radioluminescent phototherapy eye device
US11400307B2 (en) 2018-01-31 2022-08-02 California Institute Of Technology Controllable ocular phototherapy
KR20250031766A (ko) 2023-08-29 2025-03-07 주식회사 엠에스씨랩 트로카에 의해 형성된 공막의 천공을 메우기 위한 안과용 실링기구

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439198A (en) * 1981-07-09 1984-03-27 University Of Illinois Foundation Biodegradable ocular insert for controlled delivery of ophthalmic medication
US4634418A (en) * 1984-04-06 1987-01-06 Binder Perry S Hydrogel seton
US4863457A (en) * 1986-11-24 1989-09-05 Lee David A Drug delivery device
US5098443A (en) * 1989-03-23 1992-03-24 University Of Miami Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents
US5164188A (en) * 1989-11-22 1992-11-17 Visionex, Inc. Biodegradable ocular implants
KR0185215B1 (ko) * 1990-11-30 1999-05-01 요시다 쇼오지 서방성 안구삽입용 약제
JPH04364857A (ja) * 1991-06-12 1992-12-17 Asahi Chem Ind Co Ltd 涙道せき止め用ロッド

Also Published As

Publication number Publication date
KR950701209A (ko) 1995-03-23
DK0654256T3 (da) 2000-12-18
ATE195065T1 (de) 2000-08-15
DE69425411D1 (de) 2000-09-07
KR100313268B1 (ko) 2002-11-22
FI945014A7 (fi) 1994-10-25
PT654256E (pt) 2000-12-29
GR3034526T3 (en) 2000-12-29
NO944060D0 (no) 1994-10-25
NO303665B1 (no) 1998-08-17
EP0654256A1 (en) 1995-05-24
EP0654256B1 (en) 2000-08-02
FI945014A0 (fi) 1994-10-25
WO1994018921A1 (en) 1994-09-01
FI945014L (fi) 1994-10-25
CA2118515A1 (en) 1994-02-23
EP0654256A4 (en) 1995-01-04
NO944060L (no) 1994-10-25
DE69425411T2 (de) 2001-02-08

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