ES2141073T1 - Nuevos reactivos y metodo de lisis de eritrocitos. - Google Patents
Nuevos reactivos y metodo de lisis de eritrocitos.Info
- Publication number
- ES2141073T1 ES2141073T1 ES99430007T ES99430007T ES2141073T1 ES 2141073 T1 ES2141073 T1 ES 2141073T1 ES 99430007 T ES99430007 T ES 99430007T ES 99430007 T ES99430007 T ES 99430007T ES 2141073 T1 ES2141073 T1 ES 2141073T1
- Authority
- ES
- Spain
- Prior art keywords
- lysis
- erythrocytes
- new reagents
- agent
- lythis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000009089 cytolysis Effects 0.000 title abstract 4
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- 210000003743 erythrocyte Anatomy 0.000 title 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 229940127090 anticoagulant agent Drugs 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
UN REACTIVO DE LISIS UTILIZABLE PARA EL ANALISIS CITOMETRICO DE LOS LEUCOCITOS CARACTERIZADO PORQUE EL AGENTE DE LISIS ES UN HETEROCICLO NITROGENADO UTILIZADO CON UN PH COMPRENDIDO ENTRE 4 Y 9 Y PROCEDIMIENTO DE LISIS DE LOS ERITROCITOS EN EL QUE SE SOMETE A LA ACCION DE DICHO REACTIVO DE LISIS UNA MUESTRA DE SANGRE TOTAL TRATADA CON UN AGENTE ANTICOAGULANTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9806055A FR2778413B1 (fr) | 1998-05-07 | 1998-05-07 | Nouveaux reactifs et methode de lyse des erythrocytes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2141073T1 true ES2141073T1 (es) | 2000-03-16 |
Family
ID=9526319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99430007T Pending ES2141073T1 (es) | 1998-05-07 | 1999-05-04 | Nuevos reactivos y metodo de lisis de eritrocitos. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6143567A (es) |
| EP (1) | EP0955543B1 (es) |
| JP (2) | JPH11352125A (es) |
| AT (1) | ATE237806T1 (es) |
| AU (1) | AU747910B2 (es) |
| DE (2) | DE955543T1 (es) |
| ES (1) | ES2141073T1 (es) |
| FR (1) | FR2778413B1 (es) |
| GR (1) | GR990300041T1 (es) |
| NO (1) | NO992206L (es) |
| NZ (1) | NZ335594A (es) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2813891B1 (fr) * | 2000-09-14 | 2005-01-14 | Immunotech Sa | Reactif multifonctionnel pour erythrocytes mettant en jeu des carbamates et applications |
| US7465584B2 (en) * | 2005-01-24 | 2008-12-16 | Sysmex Corporation | Method and reagent for classifying leukocytes in animal blood |
| PT3035798T (pt) * | 2013-08-20 | 2018-11-22 | Univ Yeditepe | Meio de criopreservação de células com boro adicionado |
| EP3151866B1 (en) | 2014-06-09 | 2023-03-08 | Voyager Therapeutics, Inc. | Chimeric capsids |
| KR20170096998A (ko) | 2014-11-05 | 2017-08-25 | 보이저 테라퓨틱스, 인크. | 파킨슨병의 치료를 위한 aadc 폴리뉴클레오티드 |
| WO2016077687A1 (en) | 2014-11-14 | 2016-05-19 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| WO2016077689A1 (en) | 2014-11-14 | 2016-05-19 | Voyager Therapeutics, Inc. | Modulatory polynucleotides |
| WO2016094783A1 (en) | 2014-12-12 | 2016-06-16 | Voyager Therapeutics, Inc. | Compositions and methods for the production of scaav |
| EP3368054A4 (en) | 2015-10-28 | 2019-07-03 | Voyager Therapeutics, Inc. | REGULATORY EXPRESSION USING THE ADENO-ASSOCIATED VIRUS (AAV) |
| US10215683B2 (en) | 2015-11-02 | 2019-02-26 | Chiranjit Deka | Light scatter based apparatus and methods for hematology analysis using only three detectors |
| EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| EP3448987A4 (en) | 2016-04-29 | 2020-05-27 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| CA3024448C (en) | 2016-05-18 | 2025-09-09 | Voyager Therapeutics, Inc. | MODULATING POLYNUCLEOTIDES |
| BR112018073472A2 (pt) | 2016-05-18 | 2019-08-27 | Voyager Therapeutics Inc | composições e métodos de tratamento da doença de huntington |
| JP2019531787A (ja) | 2016-08-30 | 2019-11-07 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 生物医学的ターゲティング及びデリバリーの方法並びにそれを実行するための装置及びシステム |
| WO2018048586A1 (en) * | 2016-09-06 | 2018-03-15 | Chiranjit Deka | Improved reagent and method for identification and enumeration of basophils |
| WO2018204786A1 (en) | 2017-05-05 | 2018-11-08 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| SG11201909868YA (en) | 2017-05-05 | 2019-11-28 | Voyager Therapeutics Inc | Compositions and methods of treating huntington's disease |
| WO2018220835A1 (ja) * | 2017-06-02 | 2018-12-06 | 日立化成株式会社 | 血液試料中の希少細胞を分離する方法及び該細胞の遺伝子を解析する方法 |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| CA3070087A1 (en) | 2017-07-17 | 2019-01-24 | Voyager Therapeutics, Inc. | Trajectory array guide system |
| EP3662060A2 (en) | 2017-08-03 | 2020-06-10 | Voyager Therapeutics, Inc. | Compositions and methods for delivery of aav |
| BR102018015288A2 (pt) | 2017-08-08 | 2021-11-09 | Euroimmun Medizinische Labordiagnostika Ag | Método para comprovar uma ativação de basófilos |
| EP3441763A1 (de) | 2017-08-08 | 2019-02-13 | Euroimmun Medizinische Labordiagnostika AG | Verfahren zum nachweis einer basophilenaktivierung |
| CA3075656A1 (en) | 2017-09-29 | 2019-04-04 | Voyager Therapeutics, Inc. | Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery |
| WO2019079240A1 (en) | 2017-10-16 | 2019-04-25 | Voyager Therapeutics, Inc. | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| EP4454654A3 (en) | 2017-10-16 | 2025-02-19 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
| US20210010028A1 (en) | 2018-03-06 | 2021-01-14 | Voyager Therapeutics, Inc. | Insect cell manufactured partial self-complementary aav genomes |
| JP2021523914A (ja) | 2018-05-15 | 2021-09-09 | ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. | パーキンソン病を治療するための組成物および方法 |
| US20210214749A1 (en) | 2018-05-16 | 2021-07-15 | Voyager Therapeutics, Inc. | Directed evolution |
| EP3793686A1 (en) | 2018-05-16 | 2021-03-24 | Voyager Therapeutics, Inc. | Aav serotypes for brain specific payload delivery |
| JP7565218B2 (ja) | 2018-07-02 | 2024-10-10 | ボイジャー セラピューティクス インコーポレイテッド | 筋萎縮性側索硬化症および脊髄に関連する障害の治療 |
| US20210355454A1 (en) | 2018-07-24 | 2021-11-18 | Voyager Therapeutics, Inc. | Systems and methods for producing gene therapy formulations |
| JP7528066B2 (ja) | 2018-09-28 | 2024-08-05 | ボイジャー セラピューティクス インコーポレイテッド | 操作されたプロモータを有するフラタキシン発現コンストラクトおよびその使用方法 |
| US20210348242A1 (en) | 2018-10-04 | 2021-11-11 | Voyager Therapeutics, Inc. | Methods for measuring the titer and potency of viral vector particles |
| US20220064671A1 (en) | 2019-01-18 | 2022-03-03 | Voyager Therapeutics, Inc. | Methods and systems for producing aav particles |
| EP3962536A1 (en) | 2019-04-29 | 2022-03-09 | Voyager Therapeutics, Inc. | Systems and methods for producing baculoviral infected insect cells (biics) in bioreactors |
| WO2021030125A1 (en) | 2019-08-09 | 2021-02-18 | Voyager Therapeutics, Inc. | Cell culture medium for use in producing gene therapy products in bioreactors |
| TW202122582A (zh) | 2019-08-26 | 2021-06-16 | 美商航海家醫療公司 | 病毒蛋白之控制表現 |
| CN111504887B (zh) * | 2020-05-09 | 2023-05-09 | 苏州四正柏生物科技有限公司 | 一种溶血素及其制备方法 |
| WO2022032153A1 (en) | 2020-08-06 | 2022-02-10 | Voyager Therapeutics, Inc. | Cell culture medium for use in producing gene therapy products in bioreactors |
| US20240141377A1 (en) | 2021-03-03 | 2024-05-02 | Voyager Therapeutics, Inc. | Controlled expression of viral proteins |
| US20240141378A1 (en) | 2021-03-03 | 2024-05-02 | Voyager Therapeutics, Inc. | Controlled expression of viral proteins |
| WO2024054983A1 (en) | 2022-09-08 | 2024-03-14 | Voyager Therapeutics, Inc. | Controlled expression of viral proteins |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3884579A (en) * | 1973-06-14 | 1975-05-20 | Cambridge Chemical Products In | Method for counting blood platelets |
| US4284412A (en) * | 1979-07-13 | 1981-08-18 | Ortho Diagnostics, Inc. | Method and apparatus for automated identification and enumeration of specified blood cell subclasses |
| US4637986A (en) * | 1983-08-22 | 1987-01-20 | Ortho Diagnostic Systems, Inc. | Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part WBC count |
| US4902613A (en) * | 1984-05-14 | 1990-02-20 | Becton, Dickinson And Company | Lysing agent for analysis of peripheral blood cells |
| US5188935A (en) * | 1984-05-31 | 1993-02-23 | Coulter Electronics, Inc. | Reagent system and method for identification, enumeration and examination of classes and subclasses of blood leukocytes |
| JP2836865B2 (ja) * | 1989-10-23 | 1998-12-14 | 東亜医用電子株式会社 | 血液中の白血球およびヘモグロビンの測定用試薬 |
| US5316951A (en) * | 1991-06-07 | 1994-05-31 | Carver Jr Edward L | Method for the improved determination of white blood cell subpopulations |
| JP3177863B2 (ja) * | 1992-07-17 | 2001-06-18 | 東ソー株式会社 | 不安定型糖化ヘモグロビンの除去方法 |
| DE69434942T2 (de) * | 1993-02-25 | 2007-11-29 | Abbott Laboratories, Abbott Park | Mehrzweckreagenzsystem zur schnellen lysierung von vollblutproben |
| FR2705360B1 (fr) * | 1993-05-19 | 1995-08-18 | Immunotech Sa | Méthode et composition pour la lyse des érythrocytes, composition de sang, et méthode d'analyse leucocytaire. |
| FR2705359B1 (fr) * | 1993-05-19 | 1995-08-18 | Immunotech Sa | Méthode de protection des cellules leucocytaires, composition protectrice, composition de sang protégée, et méthode d'analyse sanguine. |
| JPH08189924A (ja) * | 1994-03-07 | 1996-07-23 | Sekisui Chem Co Ltd | 安定型糖化ヘモグロビンの測定方法 |
| JP3324050B2 (ja) * | 1994-10-31 | 2002-09-17 | 日本光電工業株式会社 | 白血球分類用試薬および白血球分類方法 |
| US5763280A (en) * | 1997-01-21 | 1998-06-09 | Coulter International Corp. | Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis |
| JP3830613B2 (ja) * | 1997-04-18 | 2006-10-04 | シスメックス株式会社 | 血液中の白血球及びヘモグロビン濃度測定試薬 |
| CN1278269A (zh) * | 1997-11-07 | 2000-12-27 | 第一制药株式会社 | 哌嗪-环糊精复合体 |
-
1998
- 1998-05-07 FR FR9806055A patent/FR2778413B1/fr not_active Expired - Fee Related
-
1999
- 1999-05-04 ES ES99430007T patent/ES2141073T1/es active Pending
- 1999-05-04 DE DE0955543T patent/DE955543T1/de active Pending
- 1999-05-04 EP EP99430007A patent/EP0955543B1/fr not_active Expired - Lifetime
- 1999-05-04 GR GR990300041T patent/GR990300041T1/el unknown
- 1999-05-04 AT AT99430007T patent/ATE237806T1/de not_active IP Right Cessation
- 1999-05-04 DE DE69906859T patent/DE69906859T2/de not_active Expired - Lifetime
- 1999-05-05 US US09/305,361 patent/US6143567A/en not_active Expired - Lifetime
- 1999-05-05 NZ NZ335594A patent/NZ335594A/en unknown
- 1999-05-06 AU AU26984/99A patent/AU747910B2/en not_active Ceased
- 1999-05-06 NO NO992206A patent/NO992206L/no not_active Application Discontinuation
- 1999-05-07 JP JP11127385A patent/JPH11352125A/ja not_active Withdrawn
-
2008
- 2008-06-23 JP JP2008163866A patent/JP4446059B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO992206L (no) | 1999-11-08 |
| FR2778413B1 (fr) | 2000-08-04 |
| JP2008224696A (ja) | 2008-09-25 |
| DE69906859D1 (de) | 2003-05-22 |
| DE69906859T2 (de) | 2004-01-29 |
| EP0955543A1 (fr) | 1999-11-10 |
| JP4446059B2 (ja) | 2010-04-07 |
| US6143567A (en) | 2000-11-07 |
| GR990300041T1 (en) | 2000-01-31 |
| JPH11352125A (ja) | 1999-12-24 |
| AU747910B2 (en) | 2002-05-30 |
| ATE237806T1 (de) | 2003-05-15 |
| AU2698499A (en) | 2000-04-13 |
| NZ335594A (en) | 2000-02-28 |
| DE955543T1 (de) | 2000-06-08 |
| FR2778413A1 (fr) | 1999-11-12 |
| NO992206D0 (no) | 1999-05-06 |
| EP0955543B1 (fr) | 2003-04-16 |
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