[go: up one dir, main page]

ES2038127T3 - Procedimiento para preparar monosulfactamas. - Google Patents

Procedimiento para preparar monosulfactamas.

Info

Publication number
ES2038127T3
ES2038127T3 ES198787100056T ES87100056T ES2038127T3 ES 2038127 T3 ES2038127 T3 ES 2038127T3 ES 198787100056 T ES198787100056 T ES 198787100056T ES 87100056 T ES87100056 T ES 87100056T ES 2038127 T3 ES2038127 T3 ES 2038127T3
Authority
ES
Spain
Prior art keywords
monosulfactams
preparing
procedure
group
acilamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787100056T
Other languages
English (en)
Inventor
Joseph Edward Sundeen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of ES2038127T3 publication Critical patent/ES2038127T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE MUESTRA LA ACTIVIDAD ANTIBACTERIANA DE LOS ANTIBIOTICOS DE BETA-LACTAMA MONOCICLICOS QUE TIENEN EN LA POSICION 1 UN GRUPO ACTIVADOR -O-SO3H Y EN LA POSICION 3 UN GRUPO ACILAMINO DE LA FORMULA (I) EN LA QUE R3 Y R4 SON, CADA UNO DE ELLOS INDEPENDIENTEMENTE, HIDROGENO O ALQUILO.
ES198787100056T 1986-01-06 1987-01-05 Procedimiento para preparar monosulfactamas. Expired - Lifetime ES2038127T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/816,475 US4684722A (en) 1986-01-06 1986-01-06 Monosulfactams

Publications (1)

Publication Number Publication Date
ES2038127T3 true ES2038127T3 (es) 1993-07-16

Family

ID=25220721

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787100056T Expired - Lifetime ES2038127T3 (es) 1986-01-06 1987-01-05 Procedimiento para preparar monosulfactamas.

Country Status (21)

Country Link
US (1) US4684722A (es)
EP (1) EP0229012B1 (es)
JP (1) JPS62158278A (es)
KR (1) KR900002244B1 (es)
AT (1) ATE64393T1 (es)
AU (3) AU602133B2 (es)
CA (1) CA1308107C (es)
DD (3) DD256700A5 (es)
DE (1) DE3770644D1 (es)
DK (1) DK3087A (es)
ES (1) ES2038127T3 (es)
FI (1) FI870030A7 (es)
GR (1) GR3002312T3 (es)
HU (2) HU198926B (es)
IL (1) IL81153A (es)
NO (1) NO166860C (es)
NZ (1) NZ218682A (es)
PH (1) PH23052A (es)
SU (1) SU1517762A3 (es)
YU (2) YU227886A (es)
ZA (1) ZA8771B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6452767A (en) * 1986-03-19 1989-02-28 Banyu Pharma Co Ltd 2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-vinyloxyimino)acetic acid derivative and production thereof
JPS6393796A (ja) * 1986-10-09 1988-04-25 Shin Etsu Chem Co Ltd ペプチド合成の脱保護基用薬剤
US5143913A (en) * 1988-04-04 1992-09-01 E. R. Squibb & Sons, Inc. [3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate
JPH07165740A (ja) * 1994-11-07 1995-06-27 Banyu Pharmaceut Co Ltd ２−（２−アミノチアゾリル）−２−（１−カルボキシ−１−ビニルオキシイミノ）酢酸及びその製法
CA2242877A1 (en) * 1996-01-16 1997-07-24 Merck & Co., Inc. Integrin receptor antagonists
US5952306A (en) * 1996-01-16 1999-09-14 Merck & Co., Inc. Integrin receptor antagonists
WO2015051101A1 (en) 2013-10-02 2015-04-09 Cubist Pharmaceuticals, Inc. B-lactamase inhibitor picoline salt
MA44083A (fr) 2015-12-15 2021-06-02 Merck Sharp & Dohme Composés de biarylmonobactame pour le traitement d'infections bactériennes
JP7034929B2 (ja) 2016-03-07 2022-03-14 メルク・シャープ・アンド・ドーム・コーポレーション 二環式アリールモノバクタム化合物及び細菌感染症を治療するためにそれらを使用する方法
US10002721B1 (en) * 2017-02-27 2018-06-19 Carling Technologies, Inc. Multiple contact circuit breaker
PE20201256A1 (es) 2017-10-02 2020-11-16 Merck Sharp & Dohme Compuestos monobactamicos cromanos para el tratamiento de infecciones bacterianas
CN113754651B (zh) * 2020-06-02 2023-04-18 中国医学科学院医药生物技术研究所 一种β-内酰胺化合物、其用途及其制备方法
CN118255695B (zh) * 2024-02-26 2025-03-14 广州艾奇西医药科技有限公司 一种β-内酰胺类化合物的中间体的纯化方法和制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU526540B2 (en) * 1976-04-12 1983-01-20 Fujisawa Pharmaceutical Co., Ltd. Oximes of substituted phenyl, thiazolyl - glyoxylic acids
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
GB1602725A (en) * 1977-04-27 1981-11-18 Glaxo Operations Ltd 7-(a-oxyiminoacetamido)-ceph-3-em-4-carboxylic acid derivatives
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4533660A (en) * 1980-10-31 1985-08-06 E. R. Squibb & Sons, Inc. Antibacterial O-sulfated β-lactam hydroxamic acids
JPS58113174A (ja) * 1981-12-26 1983-07-05 Toyama Chem Co Ltd 新規なアゼチジン誘導体またはその塩類を含有する抗菌剤
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
AU564150B2 (en) * 1982-04-30 1987-08-06 Takeda Chemical Industries Ltd. 1-sulfo-2-azetidinone derivatives
JPS58206589A (ja) * 1982-05-26 1983-12-01 Yamanouchi Pharmaceut Co Ltd ２−アゼチジノン誘導体
CA1203806A (en) * 1982-05-31 1986-04-29 Susumu Nakagawa 2-oxo-1-azetidinesulfonic acid derivatives, process for production thereof, and use thereof
JPS58210060A (ja) * 1982-05-31 1983-12-07 Takeda Chem Ind Ltd ２−オキソアゼチジン誘導体、その製造法および用途
EP0096297B1 (de) * 1982-06-03 1988-06-15 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von 1-Sulfo-2-oxoazetidinderivaten
DE3372768D1 (de) * 1982-06-03 1987-09-03 Hoffmann La Roche 1-sulfo-2-oxoazetidine derivatives
US4704457A (en) * 1982-06-21 1987-11-03 E. R. Squibb & Sons, Inc. Process for the preparation of (3S)-3-[[[2-(protected amino)-4-thiazolyl]-oxoacetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
DE3342929A1 (de) * 1983-11-26 1985-06-05 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
YU127887A (en) 1988-04-30
DD267039A5 (de) 1989-04-19
AU5885090A (en) 1990-11-15
IL81153A0 (en) 1987-08-31
NO870031L (no) 1987-07-07
CA1308107C (en) 1992-09-29
FI870030A0 (fi) 1987-01-05
US4684722A (en) 1987-08-04
DK3087A (da) 1987-07-07
EP0229012A1 (en) 1987-07-15
HUT48876A (en) 1989-07-28
PH23052A (en) 1989-03-10
HU198926B (en) 1989-12-28
DK3087D0 (da) 1987-01-05
IL81153A (en) 1991-06-10
HU198700B (en) 1989-11-28
NO166860B (no) 1991-06-03
ZA8771B (en) 1987-08-26
ATE64393T1 (de) 1991-06-15
NO166860C (no) 1991-09-11
YU227886A (en) 1988-02-29
NZ218682A (en) 1990-05-28
FI870030L (fi) 1987-07-07
AU6680886A (en) 1987-07-09
KR900002244B1 (ko) 1990-04-07
NO870031D0 (no) 1987-01-05
SU1517762A3 (ru) 1989-10-23
AU602133B2 (en) 1990-10-04
FI870030A7 (fi) 1987-07-07
DD267035A5 (de) 1989-04-19
JPS62158278A (ja) 1987-07-14
GR3002312T3 (en) 1992-12-30
DE3770644D1 (de) 1991-07-18
HUT44540A (en) 1988-03-28
DD256700A5 (de) 1988-05-18
KR870007164A (ko) 1987-08-17
AU617059B2 (en) 1991-11-14
AU5885190A (en) 1990-10-25
EP0229012B1 (en) 1991-06-12

Similar Documents

Publication Publication Date Title
ES2040261T3 (es) Procedimiento para preparar acidos 6-fluor-4-oxo-1,4-dihidroquinolina-3-carboxilicos sustituidos y acidos 9-fluor-3-metil-7-oxo-2,3-dihidro-7h-pirido(1,2,3-de)(1,4)benzoxazina-6-carboxilico sustituidos.
ES2066808T3 (es) Derivados de quinoleina, su produccion y uso.
PL268927A1 (en) Method of obtaining novel derivatives of benzimidazole
NO931635L (no) Fremgangsmaate for fremstilling av kinazolin-derivater
ES2080739T3 (es) Nitro-compuestos insecticidamente activos.
ES2040838T3 (es) Compuestos piperazinil-heterociclicos.
YU231790A (sh) Spirocikli koji sadrže azot
ES2038127T3 (es) Procedimiento para preparar monosulfactamas.
NO900279D0 (no) Alkylerte polyetyleniminderivater og fremgangsmaate for fremstilling derav samt anvendelse av derivatene.
DE3774918D1 (de) Cancerostatisches mittel.
SE8602404L (sv) Ny formulering
AR246509A1 (es) Una cetimina, su preparacion y un agente de entrecruzamiento que la contiene.
ES2009785B3 (es) Procedimiento para preparar derivados de tioxantona.
SE8505887L (sv) Indoler
ES2095068T3 (es) Peroxicarbonatos polimericos y procedimiento para prepararlos.
GR860117B (en) Pyridopyrimidine methods for their preparations and their use as medicaments
ES2037418T3 (es) Agentes diureticos de glutaramida enantiomerica.
ES2054186T3 (es) Composicion antihepatopatica.
ES2059374T3 (es) Substancia 4181-2 y sus derivados.
FI873060A7 (fi) Modifioitu kudosplasmiiniaktivaattori.
ES2077042T3 (es) Derivados de benzoxazina, derivados de benzotiazina y herbicidas que comprenden los mismos.
ES2101738T3 (es) Tintes de benzoxacina.
ATE118763T1 (de) Phenolisches amin als antimelanoma- und depigmentierungsmittel.
ES2043778T3 (es) Procedimiento para preparar oxiindanos y tetrahidronaftalenos herbicidas.
DK0457215T3 (da) 3-deamino-4-desoxy-4-amino-8-fluoranthracycliner samt fremgangsmåder til fremstilling deraf

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 229012

Country of ref document: ES