ES2033581A1 - New tetralone derivs. - Google Patents
New tetralone derivs.Info
- Publication number
- ES2033581A1 ES2033581A1 ES919101777A ES9101777A ES2033581A1 ES 2033581 A1 ES2033581 A1 ES 2033581A1 ES 919101777 A ES919101777 A ES 919101777A ES 9101777 A ES9101777 A ES 9101777A ES 2033581 A1 ES2033581 A1 ES 2033581A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- substd
- alkoxy
- hydroxy
- opt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- XHLHPRDBBAGVEG-UHFFFAOYSA-N 1-tetralone Chemical compound C1=CC=C2C(=O)CCCC2=C1 XHLHPRDBBAGVEG-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 10
- -1 alkylthiocarbonyloxy Chemical group 0.000 abstract 7
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 3
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 2
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 2
- 125000004691 alkyl thio carbonyl group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000005194 alkoxycarbonyloxy group Chemical group 0.000 abstract 1
- 125000004685 alkoxythiocarbonyl group Chemical group 0.000 abstract 1
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 abstract 1
- 125000004658 aryl carbonyl amino group Chemical group 0.000 abstract 1
- 125000005199 aryl carbonyloxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000005358 mercaptoalkyl group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 125000005010 perfluoroalkyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000005309 thioalkoxy group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Tetralones of formula (I) and their salts are new. In (I) R1 and R2 are H, alkyl, hydroxy, alkoxy, formyl, alkylcarbonyl, alkylthiocarbonyl, carboxyl, alkoxycarbonyl, alkoxythiocarbonyl, alkylcarbonyloxy, alkylthiocarbonyloxy, hydroxyalkyl, mercaptoalkyl, perfluoroalkyl, nitro, amino, cyano, halo, trifluoromethoxy, ethynyl, etc. R3 is H or alkyl R4 is alkyl or R3 + R4 are 2-5C polymethylene alkyl is 1-4C alkyl R5 is hydroxy, acetoxy or formyloxy R6 is H or R5 + R6 is a bond Z is O or NR8 R7 is a gp. R9 when Z is O or a radical R9 or C(=X)R10 when Z = NR8 R8 is H, 1-6C alkyl, 1-6C alkoxy, aryloxy, arylmethyloxy, 1-6C alkoxycarbonyloxy, arylcarbonyloxy, 1-6C alkylcarbonylamino or aryl carbonylamino X is O, S or NCN R9 is 3-6C cycloalkyl, 3-6C cycloalkenyl, phenyl or heteroaryl, all opt. substd. by 1 or 2 halo and/or 1-6C alkyl, 2-4C alkenylmethyl, 2-4C alkynylmethyl or R11 R10 is H, 1-6C alkyl opt. substd. by hydroxy, 1-6C alkoxy or 1-6C alkoxycarbonyl, 2-6C alkenyl, 3-6C cycloalkyl, 3-6C cycloalkenyl, and phenyl or heteroaryl opt. substd. by halo, 1-6C alkyl or R11 and R11 is 1-6C alkoxy, thioalkoxy, alkylcarbonyloxy, alkylcarbonyl, alkylthiocarbonyl or alkoxycarbonyl, hydroxy, oxo, nitro, cyano, trifluoromethyl, carboxyl, mercapto, amino (opt. substd. by 1 or 2 1-4C alkyl or aryl).
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9101777A ES2033581B1 (en) | 1991-07-30 | 1991-07-30 | PROCEDURE FOR OBTAINING NEW TETRALONAS. |
| CA002074864A CA2074864A1 (en) | 1991-07-30 | 1992-07-29 | Tetralones with pharmacological activity |
| EP92113007A EP0525768A1 (en) | 1991-07-30 | 1992-07-30 | Tetralones with pharmacological activity |
| JP4223193A JPH0640994A (en) | 1991-07-30 | 1992-07-30 | New tetralone with pharmaceutical activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9101777A ES2033581B1 (en) | 1991-07-30 | 1991-07-30 | PROCEDURE FOR OBTAINING NEW TETRALONAS. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2033581A1 true ES2033581A1 (en) | 1993-03-16 |
| ES2033581B1 ES2033581B1 (en) | 1993-12-16 |
Family
ID=8273171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9101777A Expired - Fee Related ES2033581B1 (en) | 1991-07-30 | 1991-07-30 | PROCEDURE FOR OBTAINING NEW TETRALONAS. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2033581B1 (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0193853A2 (en) * | 1985-02-27 | 1986-09-10 | Nissan Chemical Industries Ltd. | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it |
| EP0288962A2 (en) * | 1987-04-28 | 1988-11-02 | Fujisawa Pharmaceutical Co., Ltd. | Aryl-aralkyl ethers, processes for their preparation and pharmaceutical composition comprising them |
-
1991
- 1991-07-30 ES ES9101777A patent/ES2033581B1/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0193853A2 (en) * | 1985-02-27 | 1986-09-10 | Nissan Chemical Industries Ltd. | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it |
| EP0288962A2 (en) * | 1987-04-28 | 1988-11-02 | Fujisawa Pharmaceutical Co., Ltd. | Aryl-aralkyl ethers, processes for their preparation and pharmaceutical composition comprising them |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2033581B1 (en) | 1993-12-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2129279A1 (en) | Organic compounds | |
| IL106695A0 (en) | Diketopiperazine derivatives,their preparation and use | |
| DE59509331D1 (en) | Imidazopyridines | |
| PL313971A1 (en) | Phenylosulphonyl carbamides, method of obtaining them and their application as herbicides and plant growth controlling agents | |
| ATE210129T1 (en) | NEW PYRIDONE CARBOXYLIC ACID DERIVATIVES OR SALTS THEIR AND ANTIBACTERIAL AGENTS CONTAINING THEM AS THE ACTIVE INGREDIENTS | |
| ES2033581A1 (en) | New tetralone derivs. | |
| FI941706A0 (en) | TCMTB on a solid carrier in powder form, preparation and use | |
| ES2041212A1 (en) | New tetralone derivs. - used for treating e.g. hypertension, asthma, angina, congestive heart failure, epilepsy, irritable bowel syndrome and incontinence | |
| MX9304761A (en) | NEW CATALYST COMPOUNDS AND SUPREPARATION PROCESSES. | |
| EP0551034A3 (en) | Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments | |
| CA2158060A1 (en) | Process for the preparation of .beta.-phenylisoserine derivatives | |
| BG104768A (en) | Hypnotic beta-carboline derivatives, process for their preparation and their use as medicinal products | |
| GB9220137D0 (en) | Therapeutic agents | |
| IL117150A (en) | Substituted benzenesulfonylureas and - thioureas processes for their preparation their use in the preparation of medicaments and pharmaceutical compositions containing them | |
| ES2064228A1 (en) | Tetralones with pharmacological activity, compositions containing them and process for their preparation. | |
| DE60000125D1 (en) | 7-Oxo-2,3,7,14-tetrahydro-1H-benzo [b] pyrano [3,2-h] acridinecarboxylate derivatives, process for their preparation and pharmaceutical preparations containing them | |
| ES8604894A1 (en) | Fluoralkoxyphenylsulfonyl guanidines. | |
| RO96101A (en) | ERBICIDA LICHIDA COMPOSITION | |
| AU1004195A (en) | Hydrazone derivatives | |
| FR2135740A5 (en) | Herbicidal s-aryl arylamides | |
| KR790000665B1 (en) | Process for preperation of 1,3,5 trisustituted benzenes | |
| ES8609254A1 (en) | New di:hydro-pyridine cpds. blocking calcium entry into tissue | |
| ATE124946T1 (en) | NEURO-PROTECTIVE AGENTS. | |
| PL309339A1 (en) | Novel triazoquinazolines, methods of obtaining them and their application | |
| FR2092877A1 (en) | Chloro 10 (or 11) amino 10,11 dihydro dibenzazepine derivs - with cns activity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20001009 |