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ES2033256T3 - Procedimiento para preparar derivados fluorados de la vitamina d3. - Google Patents

Procedimiento para preparar derivados fluorados de la vitamina d3.

Info

Publication number
ES2033256T3
ES2033256T3 ES198787106027T ES87106027T ES2033256T3 ES 2033256 T3 ES2033256 T3 ES 2033256T3 ES 198787106027 T ES198787106027 T ES 198787106027T ES 87106027 T ES87106027 T ES 87106027T ES 2033256 T3 ES2033256 T3 ES 2033256T3
Authority
ES
Spain
Prior art keywords
derivatives
fluorated
vitamin
preparing
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787106027T
Other languages
English (en)
Inventor
Noritaka Hamma
Yoshikazu Saito
Toshio Nishizawa
Takashi Katsumata
Itsuro Sugata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd, Taisho Pharmaceutical Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Application granted granted Critical
Publication of ES2033256T3 publication Critical patent/ES2033256T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION TRATA DE NUEVOS DERIVADOS DE LA 26,26,26,27,27,27-HEXAFLUORVITAMINA D3 QUE PROPORCIONAN EXCELENTES EFECTOS FARMACOLOGICOS, Y DE UN PROCEDIMIENTO PARA SU PREPARACION. LOS NUEVOS COMPUESTOS SE REPRESENTAN POR LA FORMULA GENERAL (I).
ES198787106027T 1986-04-25 1987-04-24 Procedimiento para preparar derivados fluorados de la vitamina d3. Expired - Lifetime ES2033256T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9459686 1986-04-25

Publications (1)

Publication Number Publication Date
ES2033256T3 true ES2033256T3 (es) 1993-03-16

Family

ID=14114652

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787106027T Expired - Lifetime ES2033256T3 (es) 1986-04-25 1987-04-24 Procedimiento para preparar derivados fluorados de la vitamina d3.

Country Status (5)

Country Link
EP (1) EP0250755B1 (es)
AT (1) ATE73767T1 (es)
CA (1) CA1314872C (es)
DE (1) DE3777464D1 (es)
ES (1) ES2033256T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ232734A (en) * 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
EP0684827A1 (en) * 1993-02-19 1995-12-06 Wisconsin Alumni Research Foundation USE OF 26,26,26,27,27,27-HEXAFLUORO-1$g(a),25-DIHYDROXYCHOLECALCIFEROL FOR THE TREATMENT OF CALCIUM METABOLISM DISORDERS
AU710931B2 (en) * 1996-02-28 1999-09-30 Sumitomo Pharmaceuticals Company, Limited Crystalline vitamin D derivative

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4248791A (en) * 1980-02-04 1981-02-03 Wisconsin Alumni Research Foundation 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
US4358406A (en) * 1981-07-27 1982-11-09 Wisconsin Alumni Research Foundation 26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol and process for preparing same
JPS59500864A (ja) 1982-05-26 1984-05-17 ウイスコンシン アラムナイ リサ−チ フオンデ−シヨン 26,26.26,27.27,27―ヘキサフルオロ―1α,25―ジヒドロキシコレステロール化合物及びその製造方法
US4495181A (en) * 1983-10-03 1985-01-22 The Regents Of The University Of California 1,25-Dihydroxy-24-oxo-vitamin D3 and 1,23,25-trihydroxy-24-oxo-vitamin D3

Also Published As

Publication number Publication date
DE3777464D1 (de) 1992-04-23
ATE73767T1 (de) 1992-04-15
EP0250755A2 (en) 1988-01-07
CA1314872C (en) 1993-03-23
EP0250755A3 (en) 1988-03-30
EP0250755B1 (en) 1992-03-18

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