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ES2032963T3 - Un procedimiento para preparar composiciones farmaceuticas. - Google Patents

Un procedimiento para preparar composiciones farmaceuticas.

Info

Publication number
ES2032963T3
ES2032963T3 ES198888304008T ES88304008T ES2032963T3 ES 2032963 T3 ES2032963 T3 ES 2032963T3 ES 198888304008 T ES198888304008 T ES 198888304008T ES 88304008 T ES88304008 T ES 88304008T ES 2032963 T3 ES2032963 T3 ES 2032963T3
Authority
ES
Spain
Prior art keywords
cimetidine
procedure
pharmaceutical compositions
preparing pharmaceutical
anticid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888304008T
Other languages
English (en)
Inventor
Gordon France
Graham Stanley Leonard
Kevin Edward Pearmain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Application granted granted Critical
Publication of ES2032963T3 publication Critical patent/ES2032963T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UNA FORMA DE DOSIFICACION FARMACEUTICA QUE COMPRENDE (I) CIMETIDINA, Y (II) ANTIACIDO, DONDE AL MENOS UNA PARTE DEL CITADO ACIDO ESTA EN FORMA DE GRANULOS QUE COMPRENDEN UN DILUYENTE SOLIDO SOLUBLE EN AGUA LIBREMENTE, EL ANTIACIDO Y UN DESINTEGRANTE INSOLUBLE EN AGUA RAPIDAMENTE HINCHABLE. LAS COMPOSICIONES DE ESTE TIPO SUPERAN EL PROBLEMA DE LA REDUCIDA BIODISPONIBILIDAD DE CIMETIDINA QUE PUEDE OCURRIR CUANDO SE ADMINISTRA CIMETIDINA SIMULTANEAMENTE CON ANTIACIDOS.
ES198888304008T 1987-05-08 1988-05-04 Un procedimiento para preparar composiciones farmaceuticas. Expired - Lifetime ES2032963T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878710965A GB8710965D0 (en) 1987-05-08 1987-05-08 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ES2032963T3 true ES2032963T3 (es) 1993-03-01

Family

ID=10617055

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888304008T Expired - Lifetime ES2032963T3 (es) 1987-05-08 1988-05-04 Un procedimiento para preparar composiciones farmaceuticas.

Country Status (13)

Country Link
US (1) US5169640A (es)
JP (1) JPH0645540B2 (es)
KR (1) KR890701102A (es)
AU (1) AU602583B2 (es)
CA (1) CA1304685C (es)
DE (1) DE3868986D1 (es)
ES (1) ES2032963T3 (es)
GB (1) GB8710965D0 (es)
GR (1) GR3004356T3 (es)
IE (1) IE60948B1 (es)
PT (1) PT87422B (es)
WO (1) WO1988008704A2 (es)
ZA (2) ZA883167B (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286489A (en) * 1985-08-26 1994-02-15 The Procter & Gamble Company Taste masking compositions
KR960011236B1 (ko) * 1987-05-08 1996-08-21 스미스 클라인 앤드 프렌취 라보라토리스 리미티드 제약학적 조성물 및 고체 제형
GB9127150D0 (en) * 1991-12-20 1992-02-19 Smithkline Beecham Plc Novel treatment
GR1002332B (el) * 1992-05-21 1996-05-16 Mcneil-Ppc Inc. Νεες φαρμακευτικες συνθεσεις που περιεχουν σιμεθεικονη.
US5622980A (en) * 1993-08-17 1997-04-22 Applied Analytical Industries, Inc. Oral compositions of H2-antagonists
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US5399356A (en) * 1994-03-24 1995-03-21 The Procter & Gamble Company Process for making solid dose forms containing bismuth
DE19529862A1 (de) * 1995-08-14 1997-02-20 Rhone Poulenc Rorer Gmbh Pharmazeutische, oral anwendbare Zubereitung
US6391338B1 (en) * 1995-09-07 2002-05-21 Biovail Technologies Ltd. System for rendering substantially non-dissoluble bio-affecting agents bio-available
TW469135B (en) * 1995-10-03 2001-12-21 Chugai Pharmaceutical Co Ltd Chewable tablet
DE69739967D1 (de) * 1996-06-14 2010-09-30 Kyowa Hakko Kirin Co Ltd Eine im Mund schnell zerfallende Tablette
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
JP3001440B2 (ja) * 1996-11-25 2000-01-24 日本電気通信システム株式会社 仮想ｌａｎ方式
US6890524B1 (en) 1997-04-04 2005-05-10 Monsanto Company Hydrolyzable delivery system using cross-linked polymeric resins as vehicles
AU6590598A (en) * 1997-04-04 1998-10-30 Monsanto Company Hydrolysable delivery system using cross-linked polymeric resins as vehicles
WO1998044952A1 (en) 1997-04-04 1998-10-15 Monsanto Company pH-SELECTIVE DELIVERY SYSTEM USING CROSS-LINKED POLYMERIC RESINS AS VEHICLES
US5939091A (en) * 1997-05-20 1999-08-17 Warner Lambert Company Method for making fast-melt tablets
SK288217B6 (sk) 2001-01-26 2014-08-05 Merck Sharp & Dohme Corp. Zmes, terapeutická kombinácia, farmaceutický prostriedok a ich použitie
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
EP1965771A1 (de) * 2005-12-21 2008-09-10 ADD Advanced Drug Delivery Technologies, Ltd. Pellets enthaltend einen kern mit einem wasserlöslichen träger
US7776831B2 (en) 2006-02-01 2010-08-17 Weg Stuart L Use of antifungal compositions to treat upper gastrointestinal conditions
WO2009095210A1 (en) * 2008-01-31 2009-08-06 Bayer Consumer Care Ag Composition comprising an antacid and a h2-antagonists
ES2357209B1 (es) * 2009-05-26 2011-12-07 Fundacion Universitaria San Pablo-Ceu Composición farmacéutica sólida a base de famotidina contra la hipersecreción gástrica y otras enfermedades relacionadas, con mayor eficacia sinérgica y más rápida actuación.
CN102958515A (zh) 2009-12-02 2013-03-06 阿普塔利斯制药有限公司 非索非那定微胶囊及含有非索非那定微胶囊的组合物
JP6018911B2 (ja) * 2012-12-27 2016-11-02 ライオン株式会社 顆粒剤、カプセル剤
TWI724629B (zh) 2018-11-16 2021-04-11 日商協和化學工業股份有限公司 緩瀉用錠劑

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3501571A (en) * 1965-12-06 1970-03-17 Smithkline Corp Novel silicone compositions and method of preparing same
GB1601833A (en) * 1978-02-06 1981-11-04 Wellcome Found Antacid formulation
US4681756A (en) * 1981-04-29 1987-07-21 Hoffman-La Roche Inc. Prevention of N-nitroso compound formation in vivo
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
CA1239349A (en) * 1983-10-10 1988-07-19 Eberhard F. Gottwald Pharmaceutical composition containing cimetidine
US4676984A (en) * 1985-08-14 1987-06-30 American Home Products Corp. Rehydratable antacid composition
KR960011236B1 (ko) * 1987-05-08 1996-08-21 스미스 클라인 앤드 프렌취 라보라토리스 리미티드 제약학적 조성물 및 고체 제형

Also Published As

Publication number Publication date
KR890701102A (ko) 1989-12-19
GR3004356T3 (es) 1993-03-31
DE3868986D1 (de) 1992-04-16
GB8710965D0 (en) 1987-06-10
ZA883212B (en) 1989-03-29
AU1714188A (en) 1988-12-06
IE60948B1 (en) 1994-09-07
WO1988008704A3 (en) 1989-02-09
PT87422A (pt) 1989-05-31
IE881369L (en) 1988-11-08
JPH0645540B2 (ja) 1994-06-15
CA1304685C (en) 1992-07-07
WO1988008704A2 (en) 1988-11-17
PT87422B (pt) 1992-08-31
ZA883167B (en) 1990-02-28
JPH02500747A (ja) 1990-03-15
US5169640A (en) 1992-12-08
AU602583B2 (en) 1990-10-18

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