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ES2031837T3 - Procedimiento para preparar un 1,2-diaminociclohexahidroxilado y complejos de platino derivados del mismo. - Google Patents

Procedimiento para preparar un 1,2-diaminociclohexahidroxilado y complejos de platino derivados del mismo.

Info

Publication number
ES2031837T3
ES2031837T3 ES198787101032T ES87101032T ES2031837T3 ES 2031837 T3 ES2031837 T3 ES 2031837T3 ES 198787101032 T ES198787101032 T ES 198787101032T ES 87101032 T ES87101032 T ES 87101032T ES 2031837 T3 ES2031837 T3 ES 2031837T3
Authority
ES
Spain
Prior art keywords
diaminociclohexahidroxilado
preparing
procedure
platinum complexes
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787101032T
Other languages
English (en)
Inventor
Joseph John Hlavka
Yang-I Lin
Panayota Bitha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2031837T3 publication Critical patent/ES2031837T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Lubricants (AREA)

Abstract

ESTA MEMORIA DESCRIBE COMPLEJOS DE PLATINO DE 3BETA, 4ALFA-DIAMINO-1ALFA, 2ALFA-CICLOHEXANODIOL, QUE POSEEN LA PROPIEDAD DE INHIBIR EL CRECIMIENTO DE TUMORES EN LOS MAMIFEROS.
ES198787101032T 1986-01-31 1987-01-26 Procedimiento para preparar un 1,2-diaminociclohexahidroxilado y complejos de platino derivados del mismo. Expired - Lifetime ES2031837T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/824,479 US4670458A (en) 1986-01-31 1986-01-31 Hydroxylated 1,2-diaminocyclohexane platinum complexes

Publications (1)

Publication Number Publication Date
ES2031837T3 true ES2031837T3 (es) 1993-01-01

Family

ID=25241505

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787101032T Expired - Lifetime ES2031837T3 (es) 1986-01-31 1987-01-26 Procedimiento para preparar un 1,2-diaminociclohexahidroxilado y complejos de platino derivados del mismo.

Country Status (8)

Country Link
US (1) US4670458A (es)
EP (1) EP0232785B1 (es)
JP (1) JPS62246543A (es)
AT (1) ATE60574T1 (es)
CA (1) CA1271774A (es)
DE (1) DE3767728D1 (es)
ES (1) ES2031837T3 (es)
GR (1) GR3001579T3 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206400A (en) * 1986-07-07 1993-04-27 Ohio State University Diastereomeric mono- and di-substituted diamino cyclohexane compounds and the method of preparation thereof
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
JPH01156990A (ja) * 1987-09-26 1989-06-20 Ajinomoto Co Inc 新規白金錯体及びその用途
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5942455A (en) * 1995-11-14 1999-08-24 Drexel University Synthesis of 312 phases and composites thereof
AU1608801A (en) * 1999-11-15 2001-05-30 Parker Hughes Institute Diamino platinum (ii) antitumor complexes
DE10226592B4 (de) * 2002-06-14 2004-07-29 Faustus Forschungs Cie. Translational Cancer Research Gmbh Tumorhemmende Platin(II)-oxalato-Komplexe

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588505A5 (es) * 1972-06-08 1977-06-15 Research Corp
ZA737823B (en) * 1972-10-18 1974-08-28 Labaz Alicyclic compounds and process for preparing the same
US4092359A (en) * 1974-02-15 1978-05-30 Schering Corporation Process for the preparation of 2,5-dideoxystreptamine and of a novel intermediate therefor
GB1578323A (en) * 1976-02-26 1980-11-05 Rustenburg Platinum Mines Ltd Compositions containing platinum
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt
US4500465A (en) * 1982-06-28 1985-02-19 Engelhard Corporation Solubilized platinum (II) complexes
DE3575144D1 (de) * 1984-12-17 1990-02-08 American Cyanamid Co Platinkomplexe von aliphatischen tricarbonsaeuren.
US4587331A (en) * 1984-12-17 1986-05-06 American Cyanamid Company Platinum complexes of polyhydroxylated alkylamines and 2-polyhydroxylated alkyl-1,2-diaminoethanes
US4567285A (en) * 1985-07-10 1986-01-28 Yoshinori Kidani Complex compounds of platinum

Also Published As

Publication number Publication date
ATE60574T1 (de) 1991-02-15
EP0232785B1 (en) 1991-01-30
JPS62246543A (ja) 1987-10-27
EP0232785A1 (en) 1987-08-19
CA1271774A (en) 1990-07-17
US4670458A (en) 1987-06-02
GR3001579T3 (en) 1992-11-23
DE3767728D1 (en) 1991-03-07

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