[go: up one dir, main page]

ES2018870B3 - Procedimiento para revestimiento de granulados - Google Patents

Procedimiento para revestimiento de granulados

Info

Publication number
ES2018870B3
ES2018870B3 ES88110355T ES88110355T ES2018870B3 ES 2018870 B3 ES2018870 B3 ES 2018870B3 ES 88110355 T ES88110355 T ES 88110355T ES 88110355 T ES88110355 T ES 88110355T ES 2018870 B3 ES2018870 B3 ES 2018870B3
Authority
ES
Spain
Prior art keywords
coating procedure
waxy
granulate coating
waxy substances
granulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88110355T
Other languages
English (en)
Inventor
Gerhard Dr Ahrens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2018870B3 publication Critical patent/ES2018870B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/006—Coating of the granules without description of the process or the device by which the granules are obtained
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/14—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in rotating dishes or pans
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31801—Of wax or waxy material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Disintegrating Or Milling (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Fertilizers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Paints Or Removers (AREA)
ES88110355T 1987-07-01 1988-06-29 Procedimiento para revestimiento de granulados Expired - Lifetime ES2018870B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3721721A DE3721721C1 (de) 1987-07-01 1987-07-01 Verfahren zur Umhuellung von Granulaten

Publications (1)

Publication Number Publication Date
ES2018870B3 true ES2018870B3 (es) 1991-05-16

Family

ID=6330667

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88110355T Expired - Lifetime ES2018870B3 (es) 1987-07-01 1988-06-29 Procedimiento para revestimiento de granulados

Country Status (10)

Country Link
US (1) US4935246A (es)
EP (1) EP0298355B1 (es)
JP (1) JPS6426514A (es)
AT (1) ATE58304T1 (es)
DE (2) DE3721721C1 (es)
DK (1) DK169164B1 (es)
ES (1) ES2018870B3 (es)
GR (1) GR3001354T3 (es)
IE (1) IE61074B1 (es)
PT (1) PT87879B (es)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006368A (en) * 1988-10-19 1991-04-09 The Dow Chemical Company Plastic particle coated with processing aid and method of coating
US5290569A (en) * 1990-04-12 1994-03-01 Shionogi & Co., Ltd. Coated composition and its preparation process
DE69123075T2 (de) * 1990-04-12 1997-03-20 Shionogi Seiyaku Kk Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung
IE65045B1 (en) * 1990-04-28 1995-10-04 Takeda Chemical Industries Ltd Granulated preparations and method of producing the same
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5714167A (en) * 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
SE467525B (sv) * 1990-10-09 1992-08-03 Nemo Ivarson Ab Foerfarande foer att oeverdraga fasta partiklar i pulverform med ett i rumstemperatur hoegviskoest eller fast material
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
US5223250A (en) * 1991-02-05 1993-06-29 Sun Smart, Inc. Visibly transparent UV sunblock cosmetic compositions
AU668862B2 (en) * 1991-02-05 1996-05-23 Basf Corporation Visibly transparent UV sunblock agents and methods of making same
US5733531A (en) * 1991-02-05 1998-03-31 Sunsmart, Inc. Composite UV sunblock compositions
ATE119805T1 (de) * 1991-07-11 1995-04-15 Glatt Gmbh Verfahren und einrichtung zum beschichten von teilchen.
US5266331A (en) * 1991-11-27 1993-11-30 Euroceltique, S.A. Controlled release oxycodone compositions
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
JPH0751288B2 (ja) * 1991-12-25 1995-06-05 株式会社奈良機械製作所 粒子の複合化方法
SE9200858L (sv) * 1992-03-20 1993-09-21 Kabi Pharmacia Ab Metod för framställning av pellets med fördröjd frisättning
US20080075781A1 (en) * 1992-11-25 2008-03-27 Purdue Pharma Lp Controlled release oxycodone compositions
US6191105B1 (en) 1993-05-10 2001-02-20 Protein Delivery, Inc. Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin
IL119660A (en) 1993-05-10 2002-09-12 Euro Celtique Sa Controlled release formulation comprising tramadol
US5681811A (en) * 1993-05-10 1997-10-28 Protein Delivery, Inc. Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
US5690959A (en) * 1993-05-29 1997-11-25 Smithkline Beecham Corporation Pharmaceutical thermal infusion process
US20070275062A1 (en) * 1993-06-18 2007-11-29 Benjamin Oshlack Controlled release oxycodone compositions
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6676967B1 (en) * 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US5891471A (en) 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
US5430021A (en) * 1994-03-18 1995-07-04 Pharmavene, Inc. Hydrophobic drug delivery systems
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
IL112143A (en) * 1994-12-26 1998-09-24 Rotem Fertilizers Ltd Method for the manufacture of sulfur-containing fertilizers
US5827537A (en) * 1995-05-04 1998-10-27 Smithkline Beecham Corporation Pharmaceutical thermal infusion process
ATE293440T1 (de) * 1995-05-09 2005-05-15 Phoqus Pharmaceuticals Ltd Pulverbeschichtungszusammensetzung für elektrostatische beschichtung von pharmazeutischen substraten
US7008668B2 (en) * 1995-05-09 2006-03-07 Phoqus Pharmaceuticals Limited Powder coating composition for electrostatic coating of pharmaceutical substrates
US5789014A (en) * 1995-12-25 1998-08-04 Shin-Etsu Chemical Co., Ltd. Method of manufacturing a solid preparation coated with non-solvent coating
DE19635405A1 (de) * 1996-08-31 1998-03-05 Henkel Kgaa Verfahren zur Herstellung granularer Waschmittelinhaltsstoffe
GB9623634D0 (en) * 1996-11-13 1997-01-08 Bpsi Holdings Inc Method and apparatus for the coating of substrates for pharmaceutical use
IE980395A1 (en) * 1998-05-22 1999-12-01 Fuisz Internat Ltd Fuisz House Method and appartus for forming and encapsulated product matrix
US6703381B1 (en) 1998-08-14 2004-03-09 Nobex Corporation Methods for delivery therapeutic compounds across the blood-brain barrier
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
US7169889B1 (en) 1999-06-19 2007-01-30 Biocon Limited Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
US6309633B1 (en) 1999-06-19 2001-10-30 Nobex Corporation Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
WO2001032148A1 (en) 1999-10-29 2001-05-10 Euro-Celtique, S.A. Controlled release hydrocodone formulations
GB0002305D0 (en) * 2000-02-01 2000-03-22 Phoqus Limited Power material for electrostatic application
JP5026630B2 (ja) * 2000-03-31 2012-09-12 小林製薬株式会社 造粒粉体及びその製造方法及び圧縮成形固形物
CN101317825A (zh) 2000-10-30 2008-12-10 欧罗赛铁克股份有限公司 控释氢可酮制剂
US6867183B2 (en) * 2001-02-15 2005-03-15 Nobex Corporation Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7060675B2 (en) * 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
UA81224C2 (uk) * 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US6835802B2 (en) * 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US6858580B2 (en) * 2001-06-04 2005-02-22 Nobex Corporation Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828305B2 (en) * 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
US6828297B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6713452B2 (en) * 2001-06-04 2004-03-30 Nobex Corporation Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US7196059B2 (en) * 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7312192B2 (en) * 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US6913903B2 (en) * 2001-09-07 2005-07-05 Nobex Corporation Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7166571B2 (en) * 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
SE0200154D0 (sv) * 2002-01-21 2002-01-21 Galenica Ab New process
US7601688B2 (en) * 2002-06-13 2009-10-13 Biocon Limited Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
GB2420297B (en) * 2003-06-18 2006-11-15 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
US20040265378A1 (en) * 2003-06-25 2004-12-30 Yingxu Peng Method and compositions for producing granules containing high concentrations of biologically active substances
GB0330171D0 (en) * 2003-12-30 2004-02-04 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
GB0407312D0 (en) * 2004-03-31 2004-05-05 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
WO2006014673A2 (en) * 2004-07-19 2006-02-09 Nobex Corporation Insulin-oligomer conjugates, formulations and uses thereof
ITMI20050485A1 (it) * 2005-03-23 2006-09-24 Truffini & Regge Farmaceutici Formulazioni granulari rivestite
CA2671200A1 (en) * 2006-07-21 2008-01-24 Lab International Srl Hydrophilic abuse deterrent delivery system
ITMI20071374A1 (it) 2007-07-10 2009-01-11 Gnosis Spa Sali stabili di s-adenosilmetionina e processo per il loro ottenimento.
KR101234540B1 (ko) 2007-10-16 2013-02-19 바이오콘 리미티드 경구 투여가능한 고형 약제학적 조성물 및 그 제조방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1077950A (fr) * 1953-06-01 1954-11-12 Procédé pour rendre des poudres hydrofuges
US3009775A (en) * 1958-04-14 1961-11-21 Internat Salt Company Inc Reduction of caking tendency of salt
BE640616A (es) * 1962-12-19
GB1044572A (en) * 1963-03-04 1966-10-05 Merck & Co Inc Pharmaceutical preparations in sustained release form
US4132753A (en) * 1965-02-12 1979-01-02 American Cyanamid Company Process for preparing oral sustained release granules
FR1583182A (es) * 1967-11-30 1969-10-24
GB1346415A (en) * 1970-05-08 1974-02-13 Lilly Industries Ltd Coating process
DE2122355A1 (de) * 1970-05-08 1971-11-25 Lilly Industries Ltd., London Vorrichtung und Verfahren zum Herstellen von Partikeln
DE2308890C2 (de) * 1973-02-23 1983-03-31 Kali-Chemie Ag, 3000 Hannover Verfahren zur Herstellung von sphärischen Teilchen aus aktivem Aluminiumoxid mit hoher mechanischer Festigkeit
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
JPS5362821A (en) * 1976-11-11 1978-06-05 Takeda Chem Ind Ltd Preparation of slow-release drug
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
JPS6124516A (ja) * 1984-07-12 1986-02-03 Fujisawa Pharmaceut Co Ltd 持続性錠剤

Also Published As

Publication number Publication date
DK169164B1 (da) 1994-09-05
JPS6426514A (en) 1989-01-27
ATE58304T1 (de) 1990-11-15
US4935246A (en) 1990-06-19
PT87879A (pt) 1989-06-30
EP0298355B1 (de) 1990-11-14
IE61074B1 (en) 1994-09-21
EP0298355A1 (de) 1989-01-11
PT87879B (pt) 1993-09-30
IE881992L (en) 1989-01-01
DE3861069D1 (de) 1990-12-20
DK361488A (da) 1989-01-02
DK361488D0 (da) 1988-06-30
DE3721721C1 (de) 1988-06-09
GR3001354T3 (en) 1992-09-11

Similar Documents

Publication Publication Date Title
ES2018870B3 (es) Procedimiento para revestimiento de granulados
ATE33097T1 (de) Zusammensetzung zum ueberziehen von nahrungsund arzneimitteln und derart ueberzogene granulate.
FI864108A0 (fi) Nytt farmaceutiskt preparat och foerfarande foer framstaellning av detsamma.
BE890425A (fr) Compositions de silicone adhesives, durcissables sous l'effet des uv, et leur procede de preparation
DE3368303D1 (en) Cellulosic materials made transparent and their application, process for their manufacture and the treating compositions
SE7611795L (sv) Dryckeskompositioner
MX159468A (es) Proceso y aparato para preparar perlas polimericas de tamano uniforme
DK0452145T3 (da) Overtrukket præparat og fremstilling deraf
IL57671A (en) Phenethanolamines,process for their preparation and pharmaceutical and animal feed compositions containing the same
GB2158833B (en) Polymer material for coating hot greenhouses
KR950702625A (ko) 비살포성 효소의 제조방법(process for dust-free enzyme manufacture)
NO813238L (no) Fremgangsmaate til fremstilling av kunststoffbelagte vaeskebeholdere.
IT980483B (it) Gruppo dell albero dei coltelli per apparecchi pelletizzatori per resine sintetiche
FR2483448B1 (fr) Composition de revetement antibuee, article faconne revetu de cette composition et procede de preparation de cet article
FI834503A7 (fi) Laite käytettäväksi valmistettaessa täytettyjä päällystetuotteita automaattisesti ja jatkuvasti.
DE3361701D1 (en) Process for the preparation of polyester resins containing phosphoric-acid groups, and their use
AR218130A1 (es) Metodo y camara de calentamiento para calentar material de carga de vidrio,particularmente"pellets"(granulos)
EP0257632A3 (en) Cross-linked polymers and process for their preparation
DE3066874D1 (en) 1,2-bis(nicotinamido)propane, process for preparing the same and pharmaceutical composition containing the same
ZA795209B (en) Polymer curing system,air-curable composition and method of preparing the composition
JPS5212680A (en) Briquetting machine
NL185567B (nl) Imidegroepen bevattende polymeren, werkwijze voor de bereiding daarvan en voortbrengsels daaruit.
NO881367L (no) Apparat til fordeling av inhomogene vaesker, spesielt gjoedselvann.
JPS56126444A (en) Device for treating powdered and granular substance, base used for said device and manufacture of said base
JPS5245592A (en) Method of coating corrosion resistant substance on heating material