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ES2013828A6 - Procedure for preparing 7-[2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetamide]-3-cephem compounds. - Google Patents

Procedure for preparing 7-[2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetamide]-3-cephem compounds.

Info

Publication number
ES2013828A6
ES2013828A6 ES8900046A ES8900046A ES2013828A6 ES 2013828 A6 ES2013828 A6 ES 2013828A6 ES 8900046 A ES8900046 A ES 8900046A ES 8900046 A ES8900046 A ES 8900046A ES 2013828 A6 ES2013828 A6 ES 2013828A6
Authority
ES
Spain
Prior art keywords
aminothiazole
hydroxyiminoacetamide
preparing
procedure
cephem compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES8900046A
Other languages
Spanish (es)
Inventor
Kazuo Sakane
Jiro Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of ES2013828A6 publication Critical patent/ES2013828A6/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Procedure for preparing 7-[2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetamide]-3-cephem compounds with the formula:<IMAGE>in which R<1> is an organic group, R<2> is a carboxy or a protected carboxy in which a reaction is produced with 7-amino-3-cephem compounds and an aminothiazole derivative.The compounds prepared are used as antimicrobial agents and growth inhibitors against pathogenic micro-organisms.
ES8900046A 1988-01-07 1989-01-05 Procedure for preparing 7-[2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetamide]-3-cephem compounds. Expired - Fee Related ES2013828A6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888800295A GB8800295D0 (en) 1988-01-07 1988-01-07 Process for preparation of 7-(2-amino-thiazol-4-y)-2-hydroxyimino-acetanidol-3-cephem compounds

Publications (1)

Publication Number Publication Date
ES2013828A6 true ES2013828A6 (en) 1990-06-01

Family

ID=10629612

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8900046A Expired - Fee Related ES2013828A6 (en) 1988-01-07 1989-01-05 Procedure for preparing 7-[2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetamide]-3-cephem compounds.

Country Status (5)

Country Link
JP (1) JP2600878B2 (en)
KR (1) KR0140887B1 (en)
CA (1) CA1340604C (en)
ES (1) ES2013828A6 (en)
GB (1) GB8800295D0 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006008160A1 (en) * 2004-07-22 2006-01-26 Sandoz Ag Tertiary amine salts of 2-(2-aminothiazole-4-yl)-2-acyloxyimino)acetic acid
WO2006008161A1 (en) * 2004-07-22 2006-01-26 Sandoz Ag Alkanoyl amide solvates of 2-(2-aminothiazole-4-yl)-2-(acyloxyimino)acetic acid

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100342600B1 (en) * 2000-03-06 2002-07-04 한미정밀화학주식회사 New Thiazole compounds and their preparations
KR100392409B1 (en) * 2000-03-20 2003-07-22 한미정밀화학주식회사 A process for preparing cephalosporine derivatives using new thiazole compound
JP2004149412A (en) * 2000-06-21 2004-05-27 Fujisawa Pharmaceut Co Ltd Method for producing 7-[2-(2-aminothiazol-4-yl)-2-lower alkoxycarbonylmethoxyiminoacetamido]-3-cephem compound
KR100451672B1 (en) * 2001-06-05 2004-10-08 한미약품 주식회사 Crystalline acid salts of cefdinir, process for their preparation and process for the preparation of cefdinir using same
EP1554289B1 (en) 2002-08-13 2011-03-09 Sandoz Ag A cefdinir intermediate
WO2004104010A1 (en) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited Crystalline form of cefdinir
US7105659B2 (en) * 2003-06-02 2006-09-12 Aurobind - Pharma Ltd. Process for preparing cefdinir
CN113372292A (en) * 2021-06-29 2021-09-10 山东昌邑四方医药化工有限公司 Preparation method of ceftazidime side chain acid

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006008160A1 (en) * 2004-07-22 2006-01-26 Sandoz Ag Tertiary amine salts of 2-(2-aminothiazole-4-yl)-2-acyloxyimino)acetic acid
WO2006008161A1 (en) * 2004-07-22 2006-01-26 Sandoz Ag Alkanoyl amide solvates of 2-(2-aminothiazole-4-yl)-2-(acyloxyimino)acetic acid

Also Published As

Publication number Publication date
CA1340604C (en) 1999-06-22
GB8800295D0 (en) 1988-02-10
KR890011893A (en) 1989-08-23
JP2600878B2 (en) 1997-04-16
JPH02790A (en) 1990-01-05
KR0140887B1 (en) 1998-06-01

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Legal Events

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FD1A Patent lapsed

Effective date: 20090107