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ES2006488A6 - A PROCEDURE FOR THE PREPARATION OF AN ANTHRACICLINE GLYCOSIDE. - Google Patents

A PROCEDURE FOR THE PREPARATION OF AN ANTHRACICLINE GLYCOSIDE.

Info

Publication number
ES2006488A6
ES2006488A6 ES878701700A ES8701700A ES2006488A6 ES 2006488 A6 ES2006488 A6 ES 2006488A6 ES 878701700 A ES878701700 A ES 878701700A ES 8701700 A ES8701700 A ES 8701700A ES 2006488 A6 ES2006488 A6 ES 2006488A6
Authority
ES
Spain
Prior art keywords
anthracicline
glycoside
procedure
preparation
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES878701700A
Other languages
Spanish (es)
Inventor
Antonino Suarato
Michele Caruso
Sergio Penco
Fernando Giuliani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of ES2006488A6 publication Critical patent/ES2006488A6/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Anthracycline glycosides represented by the general formulae (I) and (II): < IMAGE > in which R1 represents a hydrogen atom or a hydroxyl group, and their pharmaceutically acceptable addition salts with an acid. Use of these compounds as antitumour agents.
ES878701700A 1986-06-12 1987-06-01 A PROCEDURE FOR THE PREPARATION OF AN ANTHRACICLINE GLYCOSIDE. Expired ES2006488A6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868614323A GB8614323D0 (en) 1986-06-12 1986-06-12 Anthracyclines

Publications (1)

Publication Number Publication Date
ES2006488A6 true ES2006488A6 (en) 1989-05-01

Family

ID=10599357

Family Applications (1)

Application Number Title Priority Date Filing Date
ES878701700A Expired ES2006488A6 (en) 1986-06-12 1987-06-01 A PROCEDURE FOR THE PREPARATION OF AN ANTHRACICLINE GLYCOSIDE.

Country Status (24)

Country Link
JP (1) JP2516769B2 (en)
KR (1) KR950004897B1 (en)
AT (1) AT392793B (en)
AU (1) AU595328B2 (en)
BE (1) BE1000158A4 (en)
CA (1) CA1291122C (en)
CH (1) CH676985A5 (en)
DE (1) DE3719377C2 (en)
DK (1) DK169076B1 (en)
ES (1) ES2006488A6 (en)
FI (1) FI84075C (en)
FR (1) FR2600066B1 (en)
GB (2) GB8614323D0 (en)
GR (1) GR870909B (en)
HU (1) HU196220B (en)
IE (1) IE60412B1 (en)
IL (1) IL82820A0 (en)
IT (1) IT1215552B (en)
NL (1) NL8701349A (en)
NZ (1) NZ220604A (en)
PT (1) PT85056B (en)
SE (1) SE500732C2 (en)
SU (1) SU1590045A3 (en)
ZA (1) ZA874202B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110483871A (en) * 2019-08-15 2019-11-22 陈全明 A kind of HDPE double-wall corrugated pipe of anti-pressure and abrasion-proof

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3842836A1 (en) * 1988-12-20 1990-06-21 Behringwerke Ag RHODOMYCINE WITH A MODIFIED CARBOHYDRATE UNIT
GB9309663D0 (en) * 1993-05-11 1993-06-23 Erba Carlo Spa Biologically active compounds
GB9325417D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 3'- aziridino-anthracycline derivatives
GB9416007D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Anthracyclinone derivatives
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
IT1275953B1 (en) * 1995-03-22 1997-10-24 Sicor Spa PROCEDURE FOR THE PREPARATION OF ANTIBIOTICS OF THE CLASS OF ANTHRACYCLINES
GB9808027D0 (en) * 1998-04-15 1998-06-17 Pharmacia & Upjohn Spa 13-dihydro-3' aziridino anthracyclines
WO2000026223A2 (en) * 1998-11-02 2000-05-11 Board Of Regents, The University Of Texas System Methods and compositions for the manufacture of highly potent anthracycline-based antitumor agents
GB0114654D0 (en) * 2001-06-15 2001-08-08 Pharmacia & Upjohn Spa Anti-tumor compound
RU2305103C1 (en) * 2006-06-02 2007-08-27 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Uniformly tritium-labeled [3h]-14-hydroxydaunomycin of adriamycinone

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
JPS57106695A (en) * 1980-11-01 1982-07-02 Erba Carlo Spa Anthracycline g lycoside compound
GB8508079D0 (en) * 1985-03-28 1985-05-01 Erba Farmitalia Antitumor anthracyclines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110483871A (en) * 2019-08-15 2019-11-22 陈全明 A kind of HDPE double-wall corrugated pipe of anti-pressure and abrasion-proof

Also Published As

Publication number Publication date
AU595328B2 (en) 1990-03-29
GB2195998A (en) 1988-04-20
HU196220B (en) 1988-10-28
FR2600066A1 (en) 1987-12-18
FI84075C (en) 1991-10-10
AT392793B (en) 1991-06-10
DK298787D0 (en) 1987-06-11
GB8614323D0 (en) 1986-07-16
SU1590045A3 (en) 1990-08-30
FI872571A0 (en) 1987-06-09
GB2195998B (en) 1990-02-14
CH676985A5 (en) 1991-03-28
GR870909B (en) 1987-10-12
NL8701349A (en) 1988-01-04
KR950004897B1 (en) 1995-05-15
KR880000459A (en) 1988-03-26
ZA874202B (en) 1988-02-24
SE8702409D0 (en) 1987-06-10
BE1000158A4 (en) 1988-06-28
FI872571L (en) 1987-12-13
JPS62292793A (en) 1987-12-19
DK169076B1 (en) 1994-08-08
IL82820A0 (en) 1987-12-20
HUT43866A (en) 1987-12-28
PT85056A (en) 1987-07-01
DK298787A (en) 1987-12-13
SE8702409L (en) 1987-12-13
NZ220604A (en) 1989-10-27
IT1215552B (en) 1990-02-14
IE871538L (en) 1987-12-13
FI84075B (en) 1991-06-28
DE3719377C2 (en) 1995-09-28
CA1291122C (en) 1991-10-22
IE60412B1 (en) 1994-07-13
ATA144987A (en) 1990-11-15
SE500732C2 (en) 1994-08-15
PT85056B (en) 1990-03-30
DE3719377A1 (en) 1987-12-17
AU7410887A (en) 1987-12-17
FR2600066B1 (en) 1992-05-15
GB8713443D0 (en) 1987-07-15
IT8720834A0 (en) 1987-06-09
JP2516769B2 (en) 1996-07-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020401