ES2004036A6 - Procedimiento para la preparacion de derivados gonadoliberinos que contienen un acido aminocarboxilio aromatico en posicion 6 - Google Patents
Procedimiento para la preparacion de derivados gonadoliberinos que contienen un acido aminocarboxilio aromatico en posicion 6Info
- Publication number
- ES2004036A6 ES2004036A6 ES8700005A ES8700005A ES2004036A6 ES 2004036 A6 ES2004036 A6 ES 2004036A6 ES 8700005 A ES8700005 A ES 8700005A ES 8700005 A ES8700005 A ES 8700005A ES 2004036 A6 ES2004036 A6 ES 2004036A6
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical
- aminocarboxylic acid
- preparing same
- veterinary compositions
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 title 1
- 102000009165 Gonadoliberin Human genes 0.000 title 1
- 108050000048 Gonadoliberin Proteins 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical group CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 abstract 1
- -1 PHENYLALANYL GROUP Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- RWZYAGGXGHYGMB-UHFFFAOYSA-N anthranilic acid Chemical group NC1=CC=CC=C1C(O)=O RWZYAGGXGHYGMB-UHFFFAOYSA-N 0.000 abstract 1
- BEBCJVAWIBVWNZ-UHFFFAOYSA-N glycinamide Chemical group NCC(N)=O BEBCJVAWIBVWNZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/11—Gonadotropin; related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
LA INVENCION SE RELACIONA CON UN PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS NONAPEPTIDO-ETILAMINAS O DECAPEPTIDO-AMIDAS GONADOLIBERINOS DE FORMULA GENERAL (I) **FORMULA** LA QUE: X1 REPRESENTA UN GRUPO ACIDO 2)AMINOBENZOICO O 3)AMINOBENZOICO; X2 REPRESENTA UN GRUPO LEUCILO, TRIPTOFILO O FENILALANILO; X3 SIGNIFICA UN GRUPO ARGINILO, LEUCILO O GLUTAMINILO; Y X4 REPRESENTA UN GRUPO GLICILAMIDA O ETILAMIDA, ASI COMO SUS SALES DE ADICION ACIDAS. LOS DERIVADOS GONADOLIBERINOS DE LA INVENCION PUEDEN USARSE MAS EFICAZMENTE PARA FINES BIOLOGICOS DE REPRODUCCION, EN COMPARACION CON LOS DERIVADOS HASTA AHORA CONOCIDOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU8616A HU194913B (en) | 1986-01-03 | 1986-01-03 | Process for producing novel gonadoliberin derivatives containing in the sixth position aromatic amino carboxylic acid and medical preparations containing these compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2004036A6 true ES2004036A6 (es) | 1988-12-01 |
Family
ID=10947497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8700005A Expired ES2004036A6 (es) | 1986-01-03 | 1987-01-02 | Procedimiento para la preparacion de derivados gonadoliberinos que contienen un acido aminocarboxilio aromatico en posicion 6 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4758552A (es) |
| JP (1) | JPH0631314B2 (es) |
| BE (1) | BE906056A (es) |
| CH (1) | CH670830A5 (es) |
| DE (1) | DE3700166A1 (es) |
| ES (1) | ES2004036A6 (es) |
| FI (1) | FI85866C (es) |
| FR (1) | FR2595705B1 (es) |
| GB (1) | GB2185025B (es) |
| HU (1) | HU194913B (es) |
| IT (1) | IT1216835B (es) |
| NL (1) | NL8603291A (es) |
| SE (1) | SE8700016L (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU199694B (en) * | 1988-05-10 | 1990-03-28 | Innofinance Altalanos Innovaci | Process for producing citostatic pharmaceutical compositions containing gonadoliberin derivatives |
| US5039805A (en) * | 1988-12-08 | 1991-08-13 | Hoffmann-La Roche Inc. | Novel benzoic and phenylacetic acid derivatives |
| DD295857A5 (de) * | 1990-06-26 | 1991-11-14 | Akad Wissenschaften Ddr | Verfahren zur herstellung von gnrh-dekapeptiden |
| US5643877A (en) * | 1994-12-05 | 1997-07-01 | University Of Maryland Biotechnology Institute | Compounds comprising gonadotropin releasing hormone (GnRH) and methods for controlling reproduction in fish |
| US6761890B1 (en) * | 1995-06-07 | 2004-07-13 | Pepscan Systems B.V. | Peptide, immunogenic composition and vaccine or medical preparation, a method to immunize animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine |
| US20030166525A1 (en) * | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
| CA2587398A1 (en) * | 2004-11-19 | 2006-05-26 | Banyu Pharmaceutical Co., Ltd. | Gpr7-selective ligand and use thereof |
| GB2454672A (en) * | 2007-11-13 | 2009-05-20 | Mologic Ltd | Chromogenic protease substrates |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU497512B2 (en) * | 1975-04-15 | 1978-12-14 | Ici Australia Limited | Nona and deca-peptides |
| US4377515A (en) * | 1979-10-01 | 1983-03-22 | Merck & Co., Inc. | Long lasting agonists and antagonists of LH-RH |
| US4292313A (en) * | 1980-04-15 | 1981-09-29 | The Salk Institute For Biological Studies | LRF Antagonists |
| US4530920A (en) * | 1983-11-07 | 1985-07-23 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist |
| IT1178775B (it) * | 1983-12-23 | 1987-09-16 | Konzponti Valto Es Hitelbank R | Derivati della gonadoliberina e procedimento per la loro preparazione |
| DE3414595A1 (de) * | 1984-04-18 | 1985-10-31 | Hoechst Ag, 6230 Frankfurt | Verwendung von gonadoliberin und gonadoliberinagonisten zur behandlung klimakterischer beschwerden |
| US4677193A (en) * | 1985-02-22 | 1987-06-30 | The Salk Institute For Biological Studies | Peptides containing an aliphatic-aromatic ketone side chain |
| HU193607B (en) * | 1985-07-18 | 1987-11-30 | Innofinance Altalanos Innovaci | Process for production of sexual products applyable for natural or artificial insemination for mammates |
-
1986
- 1986-01-03 HU HU8616A patent/HU194913B/hu not_active IP Right Cessation
- 1986-12-23 NL NL8603291A patent/NL8603291A/nl not_active Application Discontinuation
- 1986-12-27 JP JP61309288A patent/JPH0631314B2/ja not_active Expired - Lifetime
- 1986-12-29 CH CH5230/86A patent/CH670830A5/de not_active IP Right Cessation
- 1986-12-29 BE BE1/011596A patent/BE906056A/fr not_active IP Right Cessation
- 1986-12-30 FI FI865347A patent/FI85866C/fi not_active IP Right Cessation
-
1987
- 1987-01-02 ES ES8700005A patent/ES2004036A6/es not_active Expired
- 1987-01-02 SE SE8700016A patent/SE8700016L/xx not_active Application Discontinuation
- 1987-01-02 US US07/000,177 patent/US4758552A/en not_active Expired - Fee Related
- 1987-01-02 IT IT8719002A patent/IT1216835B/it active
- 1987-01-02 FR FR878700006A patent/FR2595705B1/fr not_active Expired - Fee Related
- 1987-01-02 GB GB8700017A patent/GB2185025B/en not_active Expired
- 1987-01-05 DE DE19873700166 patent/DE3700166A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| SE8700016D0 (sv) | 1987-01-02 |
| BE906056A (fr) | 1987-06-29 |
| GB2185025B (en) | 1989-12-28 |
| FI85866C (fi) | 1992-06-10 |
| SE8700016L (sv) | 1987-07-04 |
| US4758552A (en) | 1988-07-19 |
| HUT43090A (en) | 1987-09-28 |
| GB8700017D0 (en) | 1987-02-11 |
| FI85866B (fi) | 1992-02-28 |
| NL8603291A (nl) | 1987-08-03 |
| IT8719002A0 (it) | 1987-01-02 |
| CH670830A5 (es) | 1989-07-14 |
| IT1216835B (it) | 1990-03-14 |
| JPS62228099A (ja) | 1987-10-06 |
| FI865347A0 (fi) | 1986-12-30 |
| FI865347L (fi) | 1987-07-04 |
| FR2595705B1 (fr) | 1990-10-12 |
| DE3700166A1 (de) | 1987-07-09 |
| GB2185025A (en) | 1987-07-08 |
| JPH0631314B2 (ja) | 1994-04-27 |
| HU194913B (en) | 1988-03-28 |
| FR2595705A1 (fr) | 1987-09-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19991007 |