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ES2001805A6 - Procedimiento para la preparacion de una crema terapeutica con elevada estabilidad y buena eficacia. - Google Patents

Procedimiento para la preparacion de una crema terapeutica con elevada estabilidad y buena eficacia.

Info

Publication number
ES2001805A6
ES2001805A6 ES8602247A ES8602247A ES2001805A6 ES 2001805 A6 ES2001805 A6 ES 2001805A6 ES 8602247 A ES8602247 A ES 8602247A ES 8602247 A ES8602247 A ES 8602247A ES 2001805 A6 ES2001805 A6 ES 2001805A6
Authority
ES
Spain
Prior art keywords
weight
hydrocortisone
diesters
containing hydrocortisone
creams containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8602247A
Other languages
English (en)
Inventor
Henning Sattler
Bodo Asmussen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma SA
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of ES2001805A6 publication Critical patent/ES2001805A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Confectionery (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA CREMA TERAPEUTICA CON ELEVADA ESTABILIDAD Y BUENA EFICACIA. EL PROCEDIMIENTO DE OBTENCION CONSISTE EN TRATAR CON BUENA AGITACION UNA FASE GRASA FORMADA POR EMULSION ACEITE/AGUA DE ESTERES DE ACIDOS GRASOS DE POLIOXIETILENOS Y ALCOHOLES GRASOS, Y CALENTAR A 60-80 C CON UNA FASE ACUOSA A 60-80 C BAJO VACIO. AL PRINCIPIO DE LA FORMACION DE LA EMULSION SE A ADE LA CANTIDAD CORRESPONDIENTE DE DIESTER DE HIDROCORTISONA, A UNOS 60 C Y LUEGO SE DEJA ENFRIAR Y SOLIDIFICAR LA CREMA. LA CREMA TERAPEUTICA SE APLICA PARA EL TRATAMIENTO DE ESCEMAS, DERMATITIS, PSORIASIS E INFLAMACIONES.
ES8602247A 1985-09-28 1986-09-27 Procedimiento para la preparacion de una crema terapeutica con elevada estabilidad y buena eficacia. Expired ES2001805A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853534743 DE3534743A1 (de) 1985-09-28 1985-09-28 Hydrocortisondiester enthaltende o/w-creme

Publications (1)

Publication Number Publication Date
ES2001805A6 true ES2001805A6 (es) 1988-06-16

Family

ID=6282284

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8602247A Expired ES2001805A6 (es) 1985-09-28 1986-09-27 Procedimiento para la preparacion de una crema terapeutica con elevada estabilidad y buena eficacia.

Country Status (9)

Country Link
US (1) US5023251A (es)
EP (1) EP0217146B1 (es)
JP (1) JPH0729929B2 (es)
AT (1) ATE56361T1 (es)
AU (1) AU602313B2 (es)
CA (1) CA1266615A (es)
DE (2) DE3534743A1 (es)
ES (1) ES2001805A6 (es)
ZA (1) ZA866661B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3534742A1 (de) * 1985-09-28 1987-04-09 Beiersdorf Ag Hydrocortisondiester enthaltende w/o-creme
US4992478A (en) * 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
DE3900701A1 (de) * 1989-01-12 1990-07-19 Henkel Kgaa Fliessfaehige, nichtionische fettstoffdispersion
US7910624B1 (en) 1995-03-03 2011-03-22 The Trustees Of Boston University Compositions for the treatment of blood disorders
WO1995011699A1 (en) * 1993-10-29 1995-05-04 The Trustees Of Boston University Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
DE4345186C2 (de) * 1993-12-27 1997-08-14 Galderma Sa Hydrocortison-21-acetat-17-propionat enthaltende W/O-Lotionen
DE4344697A1 (de) * 1993-12-27 1995-06-29 Beiersdorf Ag Corticosteroide enthaltende W/O-Lotion
FR2721212B1 (fr) * 1994-06-17 1996-09-13 Pf Medicament Composition et procédé d'obtention d'une émulsion de désonide.
US6011000A (en) * 1995-03-03 2000-01-04 Perrine; Susan P. Compositions for the treatment of blood disorders
CA2324426A1 (en) * 1998-02-11 1999-08-19 Douglas V. Faller Compositions and methods for the treatment of cystic fibrosis
US6228351B1 (en) 1999-05-27 2001-05-08 Daniel E. Viders Medicated lip balm
GB0310147D0 (en) * 2003-05-02 2003-06-04 Almond Julie E A composition for use in the treatment of a skin condition in a subject
US20100086581A1 (en) * 2008-10-07 2010-04-08 Ernest Bove Method for purpura reduction and prevention
WO2010105112A1 (en) * 2009-03-11 2010-09-16 Hemaquest Pharmaceuticals, Inc. Detection of short-chain fatty acids in biological samples
WO2011038224A1 (en) 2009-09-24 2011-03-31 Trustees Of Boston University Methods for treating viral disorders
MA33899B1 (fr) 2009-12-08 2013-01-02 Hemaquest Pharmaceuticals Inc Procedes et regimes a faible dose pour des troubles des globules rouges
WO2011101826A1 (en) 2010-02-22 2011-08-25 Sulur Subramaniam Vanangamudi A medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer, terbinafine and dexamethasone, and a process to make it
WO2011113013A2 (en) 2010-03-11 2011-09-15 Hemaquest Pharmaceuticals, Inc. Methods and compositions for treating viral or virally-induced conditions
WO2012049544A1 (en) 2010-10-15 2012-04-19 Sulur Subramaniam Vanangamudi A medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer, a hydrocortisone acetate as a corticosteroid, and clotrimazole as an antifungal agent, and a process to make it
WO2012049540A1 (en) 2010-10-15 2012-04-19 Sulur Subramaniam Vanangamudi A medicinal fusidic acid cream made using sodium fusidate, a corticosteroid, and an antifungal agent, and incorporating a biopolymer, and a process to make it
CN109715173A (zh) 2016-07-15 2019-05-03 维拉克塔治疗公司 供基于nk细胞的疗法使用的hdac抑制剂
PH12021552997A1 (en) 2019-05-31 2023-08-14 Viracta Subsidiary Inc Methods of treating virally associated cancers with histone deacetylase inhibitors

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU47604B (en) 1904-06-01 1905-04-18 White Hymn Furnace Company Improvements in and relating to furnaces
US3867528A (en) * 1973-10-11 1975-02-18 American Cyanamid Co Steroidal topical cream base
US3934013A (en) * 1975-02-21 1976-01-20 Syntex (U.S.A.) Inc. Pharmaceutical composition
DE2826257C3 (de) * 1978-06-15 1980-12-04 Beiersdorf Ag, 2000 Hamburg Hydrocortison-17,21-diester und Verfahren zu deren Herstellung, diese enthaltende Arzneimittel sowie Hydrocortison -17-propionat als Zwischenprodukt
DE2851544C2 (de) * 1978-11-29 1985-09-26 Beiersdorf Ag, 2000 Hamburg Fluocortolon-haltige Creme
JPS56135416A (en) * 1980-03-27 1981-10-22 Mitsubishi Chem Ind Ltd Pharmaceutical preparation for skin
DE3225848A1 (de) * 1982-07-07 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Kortikoidhaltige zubereitung zur topischen applikation
JPS59137408A (ja) * 1983-01-27 1984-08-07 Taisho Pharmaceut Co Ltd 軟膏
JPS59139315A (ja) * 1983-01-31 1984-08-10 Taisho Pharmaceut Co Ltd クリ−ム剤
DE3324415A1 (de) * 1983-07-07 1985-01-17 Beiersdorf Ag Fettsalbe
DE3534742A1 (de) * 1985-09-28 1987-04-09 Beiersdorf Ag Hydrocortisondiester enthaltende w/o-creme

Also Published As

Publication number Publication date
ATE56361T1 (de) 1990-09-15
EP0217146A3 (en) 1987-09-02
ZA866661B (en) 1987-04-29
EP0217146A2 (de) 1987-04-08
US5023251A (en) 1991-06-11
AU6270486A (en) 1987-04-02
CA1266615A (en) 1990-03-13
DE3534743A1 (de) 1987-04-02
DE3674121D1 (de) 1990-10-18
JPH0729929B2 (ja) 1995-04-05
JPS6281318A (ja) 1987-04-14
AU602313B2 (en) 1990-10-11
EP0217146B1 (de) 1990-09-12

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-09-27

PC1A Transfer granted

Owner name: GALDERMA, S.A.

PC2A Transfer of patent

Owner name: GALDERMA, S.A.

FD1A Patent lapsed

Effective date: 20060928