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ES2093636T3 - Uso de un compuesto de 15-ceto-prostaglandina para la mejora de la funcion encefalica. - Google Patents

Uso de un compuesto de 15-ceto-prostaglandina para la mejora de la funcion encefalica.

Info

Publication number
ES2093636T3
ES2093636T3 ES90312642T ES90312642T ES2093636T3 ES 2093636 T3 ES2093636 T3 ES 2093636T3 ES 90312642 T ES90312642 T ES 90312642T ES 90312642 T ES90312642 T ES 90312642T ES 2093636 T3 ES2093636 T3 ES 2093636T3
Authority
ES
Spain
Prior art keywords
compound
prostaglandina
ceto
improvement
brain function
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90312642T
Other languages
English (en)
Inventor
Ryuji Ueno
Hiroyoshi Osama
Tomio Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
R Tech Ueno Ltd
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8543990A external-priority patent/JPH07116135B2/ja
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Application granted granted Critical
Publication of ES2093636T3 publication Critical patent/ES2093636T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

EL USO DE UN COMPUESTO DE 15-QUETO-PROSTAGLANDINA PARA LA FABRICACION DE UN MEDICAMENTO PARA MEJORAR LA ACCION ENCEFALICA.
ES90312642T 1989-11-22 1990-11-21 Uso de un compuesto de 15-ceto-prostaglandina para la mejora de la funcion encefalica. Expired - Lifetime ES2093636T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP30383989 1989-11-22
JP761190 1990-01-17
JP8543990A JPH07116135B2 (ja) 1990-03-30 1990-03-30 6,15―ジケト―5―ハロプロスタグランジンe類

Publications (1)

Publication Number Publication Date
ES2093636T3 true ES2093636T3 (es) 1997-01-01

Family

ID=27277677

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90312642T Expired - Lifetime ES2093636T3 (es) 1989-11-22 1990-11-21 Uso de un compuesto de 15-ceto-prostaglandina para la mejora de la funcion encefalica.

Country Status (9)

Country Link
US (3) US5117042A (es)
EP (1) EP0435443B1 (es)
KR (2) KR0147057B1 (es)
AT (1) ATE141793T1 (es)
CA (1) CA2030345C (es)
DE (1) DE69028289T2 (es)
DK (1) DK0435443T3 (es)
ES (1) ES2093636T3 (es)
GR (1) GR3020902T3 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2131674T3 (es) * 1993-02-03 1999-08-01 Teijin Ltd Composicion farmaceutica para la terapia de la trombosis cerebral.
HU223345B1 (hu) 1995-12-20 2004-08-30 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Eljárás alfa, béta-telítetlen ketonok sztereoszelektív redukciójára
WO1997047595A1 (en) * 1996-06-10 1997-12-18 R-Tech Ueno, Ltd. Endothelin antagonist
ATE202557T1 (de) 1996-11-12 2001-07-15 Alcon Lab Inc 15-fluoro-prostaglandine als augendrucksenkende mittel
US6680339B2 (en) 1996-11-12 2004-01-20 Alcon Manufacturing, Ltd. 15-fluoro prostaglandins as ocular hypotensives
HUP0004427A3 (en) * 1997-09-09 2001-09-28 Procter & Gamble Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
BR9811774A (pt) * 1997-09-09 2000-08-29 Procter & Gamble Tetraidroprostaglandinas aromáticas substituìdas por c16-c20 úteis como agonistas fp
PT978284E (pt) * 1997-11-28 2008-10-07 Sucampo Ag Utilização de compostos 15-ceto-prostaglandina-e como antagonistas da endotelina
ES2232434T3 (es) 1999-03-05 2005-06-01 Duke University Analogos de prostaglandinas c-16 fp selectivas insaturadas.
ATE402925T2 (de) 1999-10-15 2008-08-15 Sucampo Ag Neue zusammensetzung enthaltend eine bicyclische verbindung und ein glycerid
EP1267882B1 (en) * 2000-03-24 2009-04-15 Sucampo AG Prostaglandins for the treatment of eye disease caused by light irradiation like photoretinitis
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins
US20020013294A1 (en) * 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) * 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI331920B (en) 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
TWI263505B (en) 2001-11-19 2006-10-11 Sucampo Ag Pharmaceutical composition comprising a C1C-2 channel opener
EP1841433B1 (en) * 2005-01-27 2011-11-30 Sucampo AG Composition for treating central nervous system disorders
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
US8513441B2 (en) * 2008-08-29 2013-08-20 Alphora Research Inc. Prostaglandin synthesis and intermediates for use therein
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US9382272B2 (en) 2009-01-22 2016-07-05 Apotex Pharmachem Inc. Methods of making lubiprostone and intermediates thereof
BR112014002712A8 (pt) 2011-08-05 2017-06-20 Sucampo Ag método para tratamento da esquizofrenia
CN104140410B (zh) * 2013-05-09 2017-12-15 江苏豪森药业集团有限公司 鲁比前列酮的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0153858A3 (en) * 1984-02-29 1985-12-11 The Upjohn Company The therapeutic use of prostaglandins
CA1323364C (en) * 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandins e and anti ulcer agents containing same
CA1322749C (en) * 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
CA1324129C (en) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandins of the f series
EP0292177B1 (en) * 1987-05-15 1992-03-25 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Fervescence composition
ATE82499T1 (de) * 1987-09-18 1992-12-15 R Tech Ueno Ltd Okulare hypotensivagenzien.
ES2051862T3 (es) * 1987-10-02 1994-07-01 Ueno Seiyaku Oyo Kenkyujo Kk Un metodo para producir un medicamento que tiene un efecto catartico.
JP2597649B2 (ja) * 1988-05-11 1997-04-09 株式会社上野製薬応用研究所 気管・気管支拡張剤
AU619543B2 (en) * 1988-05-11 1992-01-30 Sucampo Ag Use of 15-ketoprostaglandin e or f compounds for uterine contraction
EP0343904B1 (en) * 1988-05-23 1993-04-28 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Hypersphyxia causing composition
US5106809A (en) * 1990-12-14 1992-04-21 Exxon Research And Engineering Company High activity, high yield tin modified platinum-iridium catalysts, and reforming process utilizing such catalysts

Also Published As

Publication number Publication date
EP0435443A2 (en) 1991-07-03
EP0435443B1 (en) 1996-08-28
US5426115A (en) 1995-06-20
DE69028289T2 (de) 1997-01-09
GR3020902T3 (en) 1996-11-30
CA2030345C (en) 1998-12-08
US5117042A (en) 1992-05-26
KR0167745B1 (ko) 1999-01-15
ATE141793T1 (de) 1996-09-15
KR0147057B1 (ko) 1998-08-17
US5290811A (en) 1994-03-01
DE69028289D1 (de) 1996-10-02
DK0435443T3 (da) 1996-09-16
CA2030345A1 (en) 1991-05-23
EP0435443A3 (en) 1993-01-27
KR910009269A (ko) 1991-06-28

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