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ES2088135T3 - Inhibicion de agregacion de particulas que contienen farmacos. - Google Patents

Inhibicion de agregacion de particulas que contienen farmacos.

Info

Publication number
ES2088135T3
ES2088135T3 ES92908881T ES92908881T ES2088135T3 ES 2088135 T3 ES2088135 T3 ES 2088135T3 ES 92908881 T ES92908881 T ES 92908881T ES 92908881 T ES92908881 T ES 92908881T ES 2088135 T3 ES2088135 T3 ES 2088135T3
Authority
ES
Spain
Prior art keywords
inhibition
particles containing
containing drugs
adding particles
liposomes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92908881T
Other languages
English (en)
Inventor
Crispin G S Eley
Eric A Forssen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexstar Pharmaceuticals Inc
Original Assignee
Nexstar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2088135T3 publication Critical patent/ES2088135T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)

Abstract

SE DESCRIBE UN METODO PARA PREVENIR EL AGREGADO DE LIPOSOMAS QUE INCLUYEN UN ANION POLIVALENTE DISPUESTO SOBRE LA SUPERFICIE EXTERNA DE LOS MISMOS, QUE COMPRENDE LA ADICION DE UN CATION DIVALENTE A LA FASE ACUOSA EXTERNA.
ES92908881T 1992-02-11 1992-02-11 Inhibicion de agregacion de particulas que contienen farmacos. Expired - Lifetime ES2088135T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1992/001083 WO1993015720A1 (en) 1992-02-11 1992-02-11 Inhibition of aggregation of drug containing particles
CA002108026A CA2108026C (en) 1992-02-11 1992-02-11 Inhibition of aggregation of drug containing particles

Publications (1)

Publication Number Publication Date
ES2088135T3 true ES2088135T3 (es) 1996-08-01

Family

ID=4152422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92908881T Expired - Lifetime ES2088135T3 (es) 1992-02-11 1992-02-11 Inhibicion de agregacion de particulas que contienen farmacos.

Country Status (10)

Country Link
EP (1) EP0579703B1 (es)
JP (1) JPH06506460A (es)
AT (1) ATE136457T1 (es)
AU (1) AU652247B2 (es)
CA (1) CA2108026C (es)
DE (1) DE69209830T2 (es)
DK (1) DK0579703T3 (es)
ES (1) ES2088135T3 (es)
GR (1) GR3019961T3 (es)
WO (1) WO1993015720A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4420727A1 (de) * 1994-06-15 1995-12-21 Rovi Gmbh Hautfreundliche wäßrige Liposomendispersionen, enthaltend alpha-Hydroxycarbonsäuren und/oder alpha-Hydroxyketosäuren in ihrer Salzform
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
CA2504329C (en) 2002-11-01 2013-08-20 Biodelivery Sciences International, Inc. Geodate delivery vehicles
AU2003273009A1 (en) * 2003-10-15 2005-05-05 Ltt Bio-Pharma Co., Ltd. Method of controlling paticle size of retinoic acid nanoparticles coated with polyvalent metal inorganic salt and nanoparticles obtained by the controlling method
US20070258926A1 (en) * 2003-10-15 2007-11-08 Ltt Bio-Pharma Co., Ltd. Composition containing retinoic acid nanoparticles coated with inorganic salt of polyvalent metal

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63518B1 (en) * 1987-11-18 1995-05-03 Vestar Inc Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes

Also Published As

Publication number Publication date
DE69209830T2 (de) 1996-11-28
GR3019961T3 (en) 1996-08-31
EP0579703B1 (en) 1996-04-10
JPH06506460A (ja) 1994-07-21
AU652247B2 (en) 1994-08-18
ATE136457T1 (de) 1996-04-15
DE69209830D1 (de) 1996-05-15
DK0579703T3 (da) 1996-08-05
AU1645692A (en) 1993-09-03
EP0579703A1 (en) 1994-01-26
WO1993015720A1 (en) 1993-08-19
CA2108026A1 (en) 1993-08-12
CA2108026C (en) 2003-08-19

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