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ES2085993T3 - Proteina asociada a la pancreatitis aguda, medios para el diagnostico de la pancreatitis aguda. - Google Patents

Proteina asociada a la pancreatitis aguda, medios para el diagnostico de la pancreatitis aguda.

Info

Publication number
ES2085993T3
ES2085993T3 ES91909638T ES91909638T ES2085993T3 ES 2085993 T3 ES2085993 T3 ES 2085993T3 ES 91909638 T ES91909638 T ES 91909638T ES 91909638 T ES91909638 T ES 91909638T ES 2085993 T3 ES2085993 T3 ES 2085993T3
Authority
ES
Spain
Prior art keywords
acute pancreatitis
diagnosis
protein associated
pap
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91909638T
Other languages
English (en)
Inventor
Juan-Lucio Iovanna
Volker Keim
Jean-Charles Dagorn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Application granted granted Critical
Publication of ES2085993T3 publication Critical patent/ES2085993T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4733Acute pancreatitis-associated protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A LA FAMILIA DE LA PROTEINA (PAP) ASOCIADA A LA PANCREATITIS AGUDA EN EL HOMBRE Y EN LAS RATAS. SE REFIERE TAMBIEN A LOS FRAGMENTOS NUCLEOTIDICOS QUE CODIFICAN LAS PROTEINAS ANTERIORES. ENTRAN TAMBIEN EN EL MARCO DE LA INVENCION ANTICUERPOS QUE RECONOCEN LA PAP Y QUE SON SUSCEPTIBLES DE SER UTILIZADOS PARA EL DIAGNOSTICO DE PANCREATITIS. LA INVENCION SE REFIERE TAMBIEN A LA PRODUCCION DE LA PAP, PARTICULARMENTE POR INGENIERIA GENETICA.
ES91909638T 1990-04-20 1991-04-18 Proteina asociada a la pancreatitis aguda, medios para el diagnostico de la pancreatitis aguda. Expired - Lifetime ES2085993T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909005062A FR2661187B1 (fr) 1990-04-20 1990-04-20 Proteine associee a la pancreatite aiguue. moyens pour le diagnostic de la pancreatite aiguue.

Publications (1)

Publication Number Publication Date
ES2085993T3 true ES2085993T3 (es) 1996-06-16

Family

ID=9395934

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91909638T Expired - Lifetime ES2085993T3 (es) 1990-04-20 1991-04-18 Proteina asociada a la pancreatitis aguda, medios para el diagnostico de la pancreatitis aguda.

Country Status (11)

Country Link
US (2) US5436169A (es)
EP (1) EP0528932B1 (es)
JP (1) JP3452567B2 (es)
AT (1) ATE135371T1 (es)
CA (1) CA2081013A1 (es)
DE (1) DE69117949T2 (es)
DK (1) DK0528932T3 (es)
ES (1) ES2085993T3 (es)
FR (1) FR2661187B1 (es)
GR (1) GR3019849T3 (es)
WO (1) WO1991016428A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948634A (en) * 1988-12-21 1999-09-07 The General Hospital Coporation Neural thread protein gene expression and detection of alzheimer's disease
EP0378924B1 (en) * 1988-12-21 1996-11-13 The General Hospital Corporation Detection of neurological disease or dysfunction
FR2661187B1 (fr) * 1990-04-20 1994-08-05 Inst Nat Sante Rech Med Proteine associee a la pancreatite aiguue. moyens pour le diagnostic de la pancreatite aiguue.
FR2700011B1 (fr) * 1992-12-24 1995-02-24 Inst Nat Sante Rech Med Détection de la mucoviscidose ou d'une mutation du gêne CFTR au moyen d'un dosage de la PAP.
US5663315A (en) * 1994-12-06 1997-09-02 Alphagene, Inc. Isolated DNA encoding human GP2
US5861494A (en) * 1995-06-06 1999-01-19 Human Genome Sciences, Inc. Colon specific gene and protein
US20040254101A1 (en) * 1995-06-06 2004-12-16 Human Genome Sciences, Inc. Colon specific gene and protein and cancer
US5672685A (en) * 1995-10-04 1997-09-30 Duke University Source of apolipoprotein E and method of isolating apolipoprotein E
US5804421A (en) * 1996-10-30 1998-09-08 Eastern Virginia Medical School Of The Medical College Fo Hampton Roads High level of expression of ingap in bacterial and euraryotic cells
US5935813A (en) * 1997-03-20 1999-08-10 Incyte Pharmaceuticals, Inc. Human pancreatitis-associated protein
GB9719796D0 (en) * 1997-09-17 1997-11-19 Medical Res Council Medicament
GB2347931A (en) * 1997-09-17 2000-09-20 Medical Res Council Schwann cell mitogen
AU2003241388A1 (en) * 2002-05-09 2003-11-11 Medtronic Minimed, Inc. Immunoprotective methods for beta cell neogenesis
EP1539235A2 (en) * 2002-07-01 2005-06-15 Human Genome Sciences, Inc. Antibodies that specifically bind to reg iv
WO2004037168A2 (en) * 2002-10-18 2004-05-06 Amylin Pharmaceuticals, Inc. Treatment of pancreatitis with amylin
EP1488798A1 (en) * 2003-06-18 2004-12-22 Institut National De La Sante Et De La Recherche Medicale (Inserm) HIP/PAP polypeptide composition for use in liver regeneration and for the prevention of liver failure
US7611693B2 (en) 2003-09-17 2009-11-03 Board Of Regents, The Univerisity Of Texas System Mechanism-based targeted pancreatic beta cell imaging and therapy
US20090142338A1 (en) * 2005-03-04 2009-06-04 Curedm, Inc. Methods and Compositions for Treating Type 1 and Type 2 Diabetes Mellitus and Related Conditions
JP2008531730A (ja) * 2005-03-04 2008-08-14 キュアーディーエム、インク. I型真性糖尿病及び他の症状を治療するための方法及び薬学的組成物
CA2609667C (en) * 2005-05-25 2011-02-22 Curedm, Inc. Human proislet peptide, derivatives and analogs thereof, and methods of using same
WO2008064306A2 (en) * 2006-11-22 2008-05-29 Curedm, Inc. Methods and compositions relating to islet cell neogenesis
SI2193142T1 (sl) 2007-08-30 2015-05-29 Curedm Group Holdings, Llc Sestavek in postopek za uporabo proislet peptidov in analogov le-teh
US8012928B2 (en) * 2008-12-19 2011-09-06 The Research Foundation Of State University Of New York Truncated PAP2 and methods of making and using same
EP2260857A1 (en) * 2009-06-11 2010-12-15 Alfact Innovation Novel applications of HIP/PAP or derivatives thereof
WO2014139182A1 (en) 2013-03-15 2014-09-18 Shenzhen Hightide Biopharmaceutical, Ltd. Compositions and methods of using islet neogenesis peptides and analogs thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948723A (en) * 1987-01-16 1990-08-14 Bioscience International, Inc. Method of diagnosis and severity-assessment of pancreatic disease
DE3888715T2 (de) * 1987-04-09 1994-07-14 Shionogi Seiyaku Kk Reg-Gen und dadurch kodiertes Protein.
FR2661187B1 (fr) * 1990-04-20 1994-08-05 Inst Nat Sante Rech Med Proteine associee a la pancreatite aiguue. moyens pour le diagnostic de la pancreatite aiguue.

Also Published As

Publication number Publication date
US5436169A (en) 1995-07-25
US5959086A (en) 1999-09-28
JP3452567B2 (ja) 2003-09-29
EP0528932B1 (fr) 1996-03-13
ATE135371T1 (de) 1996-03-15
DK0528932T3 (da) 1996-07-01
DE69117949D1 (de) 1996-04-18
GR3019849T3 (en) 1996-08-31
CA2081013A1 (fr) 1991-10-21
WO1991016428A1 (fr) 1991-10-31
FR2661187B1 (fr) 1994-08-05
JPH05506783A (ja) 1993-10-07
EP0528932A1 (fr) 1993-03-03
FR2661187A1 (fr) 1991-10-25
DE69117949T2 (de) 1996-08-08

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