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ES2085326T3 - Activador de plasminogeno salivar del murcielago vampiro vpa-alfa1. - Google Patents

Activador de plasminogeno salivar del murcielago vampiro vpa-alfa1.

Info

Publication number
ES2085326T3
ES2085326T3 ES90250043T ES90250043T ES2085326T3 ES 2085326 T3 ES2085326 T3 ES 2085326T3 ES 90250043 T ES90250043 T ES 90250043T ES 90250043 T ES90250043 T ES 90250043T ES 2085326 T3 ES2085326 T3 ES 2085326T3
Authority
ES
Spain
Prior art keywords
vampiro
alfa1
salivar
vpa
plasminogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90250043T
Other languages
English (en)
Inventor
Berthold Baldus
Peter Donner
Wolf-Dieter Schleuning
Alejandro Alagon
Werner Boidol
Jorn Reiner Kratzschmar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3904580A external-priority patent/DE3904580A1/de
Priority claimed from DE19893917949 external-priority patent/DE3917949A1/de
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2085326T3 publication Critical patent/ES2085326T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA PRESENTE INVENCION ES RELATIVA A NUEVOS TROMBOLITICOS DE V-PA, LOS CUALES DISUELVEN COAGULOS DE SANGRE DEL CUERPO HUMANO Y POR ESTO SON ADECUADOS PARA EL TRATAMIENTO DE INFARTO CARDIACO, POR EJEMPLO.
ES90250043T 1989-02-13 1990-02-13 Activador de plasminogeno salivar del murcielago vampiro vpa-alfa1. Expired - Lifetime ES2085326T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3904580A DE3904580A1 (de) 1989-02-13 1989-02-13 Neues thrombolytikum
DE19893917949 DE3917949A1 (de) 1989-05-30 1989-05-30 Neues thrombolytikum

Publications (1)

Publication Number Publication Date
ES2085326T3 true ES2085326T3 (es) 1996-06-01

Family

ID=25877826

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90250043T Expired - Lifetime ES2085326T3 (es) 1989-02-13 1990-02-13 Activador de plasminogeno salivar del murcielago vampiro vpa-alfa1.

Country Status (16)

Country Link
EP (1) EP0383417B1 (es)
JP (1) JP2904918B2 (es)
AT (1) ATE132187T1 (es)
AU (1) AU642404B2 (es)
BR (1) BR9007115A (es)
CA (1) CA2046632C (es)
DE (1) DE69024382T2 (es)
DK (1) DK0383417T3 (es)
ES (1) ES2085326T3 (es)
FI (1) FI103577B (es)
GR (1) GR3019328T3 (es)
HU (1) HU217219B (es)
IE (1) IE73229B1 (es)
NO (1) NO308708B1 (es)
UA (1) UA34415C2 (es)
WO (1) WO1990009438A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE69054B1 (en) * 1988-07-20 1996-08-07 Schering Ag Vampire bat salivary plasminogen activators
DE3943241A1 (de) * 1989-12-22 1991-06-27 Schering Ag Thrombolytisch wirkendes kombinationspraeparat
DE4442665A1 (de) * 1994-11-30 1996-06-05 Gruenenthal Gmbh Chimäre Proteine mit fibrinolytischen und thrombinhemmenden Eigenschaften
US5731186A (en) * 1996-02-05 1998-03-24 Schering Aktiengesellschaft Method for the production of rDSPA α1
DE10016139A1 (de) * 2000-03-27 2001-10-18 Schleuning Wolf Dieter Verfahren zur Bestimmung von löslichem Fibrin
DE10153601A1 (de) 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
AU2004240748B2 (en) * 2003-05-21 2010-07-15 Ares Trading S.A. Method of chromatographic analysis of a protein solution
DE10342518A1 (de) * 2003-09-12 2005-05-12 Paion Gmbh Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität
GB0321997D0 (en) 2003-09-19 2003-10-22 Novartis Ag Organic compound
DE202006015207U1 (de) * 2006-05-19 2007-08-16 Paion Deutschland Gmbh Verwendung vn Plasminogenaktivatoren zur Behandlung einer Venenthromboembolie
US8299221B2 (en) 2006-11-17 2012-10-30 Novartis Ag LINGO binding molecules and pharmaceutical use thereof
PL2207808T3 (pl) 2007-11-02 2013-11-29 Novartis Ag Ulepszone cząsteczki wiążące się z Nogo-A i ich zastosowania farmaceutyczne
WO2011107299A2 (en) 2010-04-16 2011-09-09 Paion Deutschland Gmbh Method for the manufacture of recombinant dspa alpha1
US20230399390A1 (en) 2019-10-24 2023-12-14 Novago Therapeutics Ag Novel anti-nogo-a antibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE69054B1 (en) * 1988-07-20 1996-08-07 Schering Ag Vampire bat salivary plasminogen activators

Also Published As

Publication number Publication date
AU5080790A (en) 1990-09-05
CA2046632A1 (en) 1990-08-14
FI913818A0 (fi) 1991-08-12
ATE132187T1 (de) 1996-01-15
FI103577B1 (fi) 1999-07-30
IE73229B1 (en) 1997-05-21
FI103577B (fi) 1999-07-30
BR9007115A (pt) 1991-11-26
NO308708B1 (no) 2000-10-16
EP0383417A1 (en) 1990-08-22
EP0383417B1 (en) 1995-12-27
JP2904918B2 (ja) 1999-06-14
IE900506L (en) 1990-08-13
HU217219B (hu) 1999-12-28
WO1990009438A1 (en) 1990-08-23
JPH04504799A (ja) 1992-08-27
HU902004D0 (en) 1991-11-28
NO913129L (no) 1991-10-11
DE69024382T2 (de) 1996-08-14
AU642404B2 (en) 1993-10-21
NO913129D0 (no) 1991-08-12
UA34415C2 (uk) 2001-03-15
CA2046632C (en) 1999-05-11
HUT59724A (en) 1992-06-29
GR3019328T3 (en) 1996-06-30
DK0383417T3 (da) 1996-05-13
DE69024382D1 (de) 1996-02-08

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