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ES2081823T3 - Agente para la aplicacion transdermica, que contiene gestoden. - Google Patents

Agente para la aplicacion transdermica, que contiene gestoden.

Info

Publication number
ES2081823T3
ES2081823T3 ES89118855T ES89118855T ES2081823T3 ES 2081823 T3 ES2081823 T3 ES 2081823T3 ES 89118855 T ES89118855 T ES 89118855T ES 89118855 T ES89118855 T ES 89118855T ES 2081823 T3 ES2081823 T3 ES 2081823T3
Authority
ES
Spain
Prior art keywords
gestoden
agent
application
transdermic
transdermic application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89118855T
Other languages
English (en)
Inventor
Clemens Gunther
Ulrich Dr Tauber
Karin Dr Schmidt-Gollwitzer
Jutta Dr Riedl
Johannes-Wilhelm Dr Tack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3836862A external-priority patent/DE3836862A1/de
Priority claimed from DE19893910578 external-priority patent/DE3910578A1/de
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2081823T3 publication Critical patent/ES2081823T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

EL INVENTO DESCRIBE UN MEDIO PARA LA APLICACION TRANSDERMAL QUE SE CARACTERIZA YA QUE EL GESTODEN CONTIENE EN COMBINACION UNO O DOS OSTROGENOS.
ES89118855T 1988-10-27 1989-10-11 Agente para la aplicacion transdermica, que contiene gestoden. Expired - Lifetime ES2081823T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3836862A DE3836862A1 (de) 1988-10-27 1988-10-27 Mittel zur transdermalen applikation von steroidhormonen
DE19893910578 DE3910578A1 (de) 1989-03-29 1989-03-29 Mittel zur transdermalen applikation enthaltend gestoden

Publications (1)

Publication Number Publication Date
ES2081823T3 true ES2081823T3 (es) 1996-03-16

Family

ID=25873728

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89118855T Expired - Lifetime ES2081823T3 (es) 1988-10-27 1989-10-11 Agente para la aplicacion transdermica, que contiene gestoden.

Country Status (21)

Country Link
US (1) US5788984A (es)
EP (3) EP0573133A1 (es)
JP (1) JP3238389B2 (es)
KR (1) KR0137463B1 (es)
CN (2) CN1036836C (es)
AT (1) ATE132751T1 (es)
AU (4) AU4374789A (es)
BG (1) BG92281A (es)
CA (1) CA2001618C (es)
DE (1) DE58909570D1 (es)
DK (1) DK175804B1 (es)
ES (1) ES2081823T3 (es)
FI (1) FI100456B (es)
GR (1) GR3019079T3 (es)
HU (1) HU210549B (es)
IE (2) IE970562A1 (es)
IL (1) IL92007A (es)
MX (1) MX173621B (es)
NO (2) NO180567C (es)
PT (1) PT92131B (es)
WO (1) WO1990004397A1 (es)

Families Citing this family (66)

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DE69133077T2 (de) * 1990-06-01 2002-11-07 The Population Council, New York Herstellung von ST1435 enthaltenden pharmazeutischen Zusammensetzungen zur topischen Verwendung
US5198223A (en) * 1990-10-29 1993-03-30 Alza Corporation Transdermal formulations, methods and devices
US5320850A (en) * 1990-10-29 1994-06-14 Alza Corporation Transdermal delivery of the gestogen ST-1435 and devices therefor
MX9101787A (es) * 1990-10-29 1992-06-05 Alza Corp Formulaciones,metodos y dispositivos anticonceptivos transdermicos
US5512292A (en) * 1990-10-29 1996-04-30 Alza Corporation Transdermal contraceptive formulations methods and devices
DE4210165A1 (de) * 1991-07-30 1993-02-04 Schering Ag Transdermale therapeutische systeme
JPH07504672A (ja) * 1992-03-21 1995-05-25 エンテック　ゲゼルシャフト　フュア　エンドクリノロギッシェ　テヒノロギー　エム．ベー．ハー． 更年期骨粗鬆症の処置に対するエストリオールの使用
JP2960832B2 (ja) * 1992-05-08 1999-10-12 ペルマテック テクノロジー アクチェンゲゼルシャフト エストラジオールの投与システム
DE4329242A1 (de) * 1993-08-26 1995-03-02 Schering Ag Mittel zur transdermalen Applikation enthaltend Gestodenester
EP0741572A1 (de) * 1994-01-27 1996-11-13 Schering Aktiengesellschaft MITTEL ZUR TRANSDERMALEN APPLIKATION ENTHALTEND 14$g(a),17$g(a)-ETHANOESTRA-1,3,5(10)-TRIEN-3,17$g(b)-DIOL
JPH0827003A (ja) * 1994-07-22 1996-01-30 Sekisui Chem Co Ltd 経皮吸収製剤
US6024974A (en) * 1995-01-06 2000-02-15 Noven Pharmaceuticals, Inc. Composition and methods for transdermal delivery of acid labile drugs
IL116539A (en) * 1995-01-06 2002-02-10 Noven Pharma Preparations given through the skin of unstable anti-acid drugs
IT1283102B1 (it) * 1996-06-06 1998-04-07 Permatec Nv Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele
KR100215027B1 (ko) * 1997-01-27 1999-08-16 성재갑 스테로이드계 약물의 경피흡수투여용 조성물 및 이를 포함하는 경피흡수투여용 제형
DE19739916C2 (de) * 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
IT1294748B1 (it) 1997-09-17 1999-04-12 Permatec Tech Ag Formulazione per un dispositivo transdermico
FR2772270B1 (fr) * 1997-12-15 2002-06-07 Besins Iscovesco Lab Utilisation d'un oestrogene pour le traitement de la depression postnatale
AU1728099A (en) 1997-12-22 1999-07-12 Alza Corporation Monoglyceride and ethyl palmitate permeation enhancer compositions
PL197492B1 (pl) * 1999-07-02 2008-04-30 Lohmann Therapie Syst Lts Transdermalny system terapeutyczny zawierający warstwę polimerową z zawartymi w niej mikrozbiornikami i sposób wytwarzania błon
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US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
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DE10107663B4 (de) * 2001-02-19 2004-09-09 Lts Lohmann Therapie-Systeme Ag Testosteronhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung
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US7858607B2 (en) * 2003-03-14 2010-12-28 Mamchur Stephen A System for use by compounding pharmacists to produce hormone replacement medicine customized for each consumer
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FR2717688B1 (fr) * 1994-03-28 1996-07-05 Lhd Lab Hygiene Dietetique Système matriciel transdermique d'administration d'un oestrogène et/ou un progestatif à base d'EVA.

Also Published As

Publication number Publication date
EP0573133A1 (de) 1993-12-08
US5788984A (en) 1998-08-04
HU896546D0 (en) 1990-12-28
EP0370220B1 (de) 1996-01-10
EP0394429A1 (de) 1990-10-31
IE81077B1 (en) 2000-02-23
AU7741698A (en) 1998-10-01
EP0370220A1 (de) 1990-05-30
NO902840L (no) 1990-06-26
CA2001618A1 (en) 1990-04-27
IE970562A1 (es) 1990-04-27
KR900005969A (ko) 1990-05-07
DE58909570D1 (de) 1996-02-22
WO1990004397A1 (de) 1990-05-03
NO180567C (no) 1997-05-14
MX173621B (es) 1994-03-18
NO902840D0 (no) 1990-06-26
CN1042075A (zh) 1990-05-16
DK138590D0 (da) 1990-06-06
NO951592D0 (no) 1995-04-26
EP0394429B1 (de) 1996-01-10
NO951592L (no) 1990-06-26
AU3001192A (en) 1993-02-11
IE893376L (en) 1990-04-27
CN1069829C (zh) 2001-08-22
IL92007A (en) 1995-12-08
DK138590A (da) 1990-06-06
PT92131A (pt) 1990-04-30
GR3019079T3 (en) 1996-05-31
AU714979B2 (en) 2000-01-13
DK175804B1 (da) 2005-03-07
ATE132751T1 (de) 1996-01-15
HU210549B (en) 1995-05-29
CA2001618C (en) 2000-06-20
FI903213A0 (fi) 1990-06-26
BG92281A (bg) 1993-12-24
NO180567B (no) 1997-02-03
CN1157719A (zh) 1997-08-27
JP3238389B2 (ja) 2001-12-10
PT92131B (pt) 1995-06-30
KR0137463B1 (ko) 1998-06-01
CN1036836C (zh) 1997-12-31
AU2059695A (en) 1995-08-31
IL92007A0 (en) 1990-07-12
AU4374789A (en) 1990-05-03
FI100456B (fi) 1997-12-15
JPH03502700A (ja) 1991-06-20

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