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ES2076608T3 - Insuflador multi-dosis para medicamentos en forma de polvo. - Google Patents

Insuflador multi-dosis para medicamentos en forma de polvo.

Info

Publication number
ES2076608T3
ES2076608T3 ES92108490T ES92108490T ES2076608T3 ES 2076608 T3 ES2076608 T3 ES 2076608T3 ES 92108490 T ES92108490 T ES 92108490T ES 92108490 T ES92108490 T ES 92108490T ES 2076608 T3 ES2076608 T3 ES 2076608T3
Authority
ES
Spain
Prior art keywords
receptacle
deposit
powder
dose
hole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92108490T
Other languages
English (en)
Inventor
Salvatore Cocozza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Miat SpA
Original Assignee
Miat SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miat SpA filed Critical Miat SpA
Application granted granted Critical
Publication of ES2076608T3 publication Critical patent/ES2076608T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • B05B11/065Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material the particulate material being separated from a main storage in discrete quantities delivered one at a time
    • B05B11/067Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material the particulate material being separated from a main storage in discrete quantities delivered one at a time the particulate material being separated from the main storage by a dosing device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/10Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation
    • G01F11/12Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements
    • G01F11/20Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates
    • G01F11/24Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber rotates or oscillates for fluent solid material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • A61M2205/071General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/075Bulb type

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

SE PRESENTA UN INSUFLADOR MULTIDOSIS PARA LA ADMINISTRACION NASAL DE MEDICAMENTOS EN FORMA DE POLVO FINO O MICRONIZADO QUE COMPRENDE UN DEPOSITO (34), UNA UNIDAD (60, 64) PARA EXTRAER Y MEDIR EL MEDICAMENTO CONTENIDO EN EL DEPOSITO, Y UNA UNIDAD INSUFLADORA (42, 46) QUE COMPRENDE UNA BOMBA (42) QUE FUNCIONA MANUALMENTE PARA GENERAR UNA CORRIENTE DE AIRE EN EL INTERIOR DEL CANAL (26) PARA TRANSPORTAR UNA DOSIS INDIVIDUAL DE MEDICAMENTO AL INTERIOR DE LA CAVIDAD NASAL DEL PACIENTE. LA UNIDAD DE EXTRACCION Y MEDIDA COMPRENDE UN DISPOSITIVO TRANSPORTADOR (60) PROVISTO CON AL MENOS UN RECEPTACULO (64) PARA EXTRAER UNA DOSIS DEL MEDICAMENTO DEL DEPOSITO (34) Y TRANSPORTARLO HASTA LA POSICION DE INSUFLADO. EL RECEPTACULO (64) TIENE UN ORIFICIO COAXIAL EN SU BASE (66) A TRAVES DEL CUAL PASA LA CORRIENTE DE AIRE GENERADA POR LA BOMBA CUANDO EL RECEPTACULO SE ENCUENTRA EN LA POSICION DE INSUFLADO. EL ORIFICIO (66) TIENE UN TAMAÑO SUBSTANCIALMENTE MAS PEQUEÑO QUE LA BOCA DEL RECEPTACULO Y ESTO ES ASIPARA EVITAR QUE EL MEDICAMENTO EN POLVO CAIGA A TRAVES DEL ORIFICIO, EN VIRTUD DE UN EFECTO DE ARQUEAMIENTO.
ES92108490T 1991-06-14 1992-05-20 Insuflador multi-dosis para medicamentos en forma de polvo. Expired - Lifetime ES2076608T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911643A IT1248059B (it) 1991-06-14 1991-06-14 Insufflatore multidose per farmaci in polvere

Publications (1)

Publication Number Publication Date
ES2076608T3 true ES2076608T3 (es) 1995-11-01

Family

ID=11360122

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92108490T Expired - Lifetime ES2076608T3 (es) 1991-06-14 1992-05-20 Insuflador multi-dosis para medicamentos en forma de polvo.

Country Status (10)

Country Link
US (1) US5250287A (es)
EP (1) EP0518087B1 (es)
JP (1) JPH05200115A (es)
AT (1) ATE125161T1 (es)
CA (1) CA2070297C (es)
DE (1) DE69203541T2 (es)
DK (1) DK0518087T3 (es)
ES (1) ES2076608T3 (es)
GR (1) GR3017598T3 (es)
IT (1) IT1248059B (es)

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UA27961C2 (uk) * 1992-12-18 2000-10-16 Шерінг Корпорейшн Інгалятор для порошкових ліків
US5634900A (en) * 1993-05-12 1997-06-03 Teijin Limited Multi-dose powdered medicine administering device and method thereof
DE4319514C2 (de) * 1993-06-14 2003-06-18 Sofotec Gmbh & Co Kg Pulverinhalator
FR2718968B1 (fr) * 1994-04-20 1996-07-26 Valois Sa Insert délimitant une chambre de dosage d'un inhalateur.
DE4415462C1 (de) * 1994-05-03 1995-08-31 Transcoject Marketing Gmbh Inhalator
GB9409851D0 (en) * 1994-05-17 1994-07-06 Cambridge Consultants Improvements in and relating to containers of particulate material
DE19518810A1 (de) * 1995-05-26 1996-11-28 Bayer Ag Nasal-Applikator
JP3434396B2 (ja) * 1995-06-30 2003-08-04 株式会社日立ユニシアオートモティブ 鼻腔用投薬器
IN188288B (es) * 1996-10-01 2002-08-31 Cipla Ltd
SE9700935D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
US6076520A (en) * 1997-05-12 2000-06-20 Cooper; Emily L. Device for nasal therapeutic inhalation
US6345617B1 (en) 1997-09-26 2002-02-12 1263152 Ontario Inc. Aerosol medication delivery apparatus and system
US6293279B1 (en) 1997-09-26 2001-09-25 Trudell Medical International Aerosol medication delivery apparatus and system
KR100629126B1 (ko) * 1999-01-14 2006-09-27 데이진 가부시키가이샤 분말체의 정량 공급장치 및 방법
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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
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AU2003220125B2 (en) * 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
US20030205226A1 (en) 2002-05-02 2003-11-06 Pre Holding, Inc. Aerosol medication inhalation system
JP3950738B2 (ja) * 2002-05-14 2007-08-01 株式会社 バイオアクティス 鼻腔用粉状薬剤施薬装置
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
CA2694183C (en) 2002-10-11 2013-06-25 Otsuka Techno Corporation Powder inhalator
US20040153027A1 (en) 2002-10-28 2004-08-05 Mantell Robert R. Dual-capacity insufflator tube
US7654975B2 (en) * 2003-04-24 2010-02-02 Northgate Technologies, Inc. Mixed-gas insufflation system
FI20031158L (fi) * 2003-08-15 2005-02-16 Perlos Oyj Inhalaattori
CA2538456C (en) * 2003-10-07 2013-01-15 Northgate Technologies Inc. System and method for delivering a substance to a body cavity
MXPA06003830A (es) * 2003-10-09 2006-07-03 Bioactis Ltd Aparato para abastecer medicina pulverizada para la cavidad nasal.
EP1680173B1 (en) 2003-10-31 2011-01-12 Trudell Medical International System for manipulating a catheter for delivering a substance to a body cavity
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
US20090253654A1 (en) * 2005-09-22 2009-10-08 Galantos Pharma Gmbh Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
DK1986679T3 (da) 2006-02-22 2017-11-20 Mannkind Corp Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
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JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
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US9205240B2 (en) * 2008-12-15 2015-12-08 Profibrix B.V. Powder delivery device
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IT1237118B (it) * 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.

Also Published As

Publication number Publication date
IT1248059B (it) 1995-01-05
DE69203541T2 (de) 1996-01-11
EP0518087B1 (en) 1995-07-19
US5250287A (en) 1993-10-05
ITMI911643A1 (it) 1992-12-14
ATE125161T1 (de) 1995-08-15
ITMI911643A0 (it) 1991-06-14
CA2070297A1 (en) 1992-12-15
CA2070297C (en) 1999-01-26
JPH05200115A (ja) 1993-08-10
DK0518087T3 (da) 1995-11-27
GR3017598T3 (en) 1996-01-31
DE69203541D1 (de) 1995-08-24
EP0518087A1 (en) 1992-12-16

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