ES2072423T3 - Anticuerpo monoclonal e inmunoensayo para el factor beta xiia de coagulacion de la sangre. - Google Patents
Anticuerpo monoclonal e inmunoensayo para el factor beta xiia de coagulacion de la sangre.Info
- Publication number
- ES2072423T3 ES2072423T3 ES90902656T ES90902656T ES2072423T3 ES 2072423 T3 ES2072423 T3 ES 2072423T3 ES 90902656 T ES90902656 T ES 90902656T ES 90902656 T ES90902656 T ES 90902656T ES 2072423 T3 ES2072423 T3 ES 2072423T3
- Authority
- ES
- Spain
- Prior art keywords
- blood coagulation
- monoclonal
- immuno
- coagulation factor
- assay antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000003018 immunoassay Methods 0.000 title abstract 2
- 102000015081 Blood Coagulation Factors Human genes 0.000 title 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 title 1
- 239000003114 blood coagulation factor Substances 0.000 title 1
- 229940019700 blood coagulation factors Drugs 0.000 title 1
- 102000000429 Factor XII Human genes 0.000 abstract 1
- 108010080865 Factor XII Proteins 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000023555 blood coagulation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
UN ANTICUERPO MONOCLONAL QUE SE ENLAZA AL FACTOR (BETA)XII Y QUE NO PRESENTA SUSTANCIALMENTE UN ENLACE AL FACTOR XII. ESTE ANTICUERPO SE PUEDE UTILIZAR EN INMUNOENSAYOS PARA MEDIR LOS NIVELES DEL FACTOR (BETA)XIIA EN LA SANGRE, POR EJEMPLO EN ESTUDIOS SOBRE LOS SISTEMAS DE COAGULACION DE LA SANGRE Y DE TRASTORNOS TROMBOTICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898901859A GB8901859D0 (en) | 1989-01-27 | 1989-01-27 | Diagnostic test |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2072423T3 true ES2072423T3 (es) | 1995-07-16 |
Family
ID=10650741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90902656T Expired - Lifetime ES2072423T3 (es) | 1989-01-27 | 1990-01-29 | Anticuerpo monoclonal e inmunoensayo para el factor beta xiia de coagulacion de la sangre. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0455707B1 (es) |
| JP (1) | JP2916252B2 (es) |
| AT (1) | ATE121788T1 (es) |
| AU (1) | AU641912B2 (es) |
| CA (1) | CA2045475C (es) |
| DE (1) | DE69018968T2 (es) |
| DK (1) | DK0455707T3 (es) |
| ES (1) | ES2072423T3 (es) |
| GB (1) | GB8901859D0 (es) |
| IL (1) | IL93207A (es) |
| NZ (1) | NZ232273A (es) |
| WO (1) | WO1990008835A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963657A (en) * | 1988-06-09 | 1990-10-16 | Temple University Of The Commonwealth System Of Higher Education | Monoclonal antibodies to the light chain region of human factor XII and methods of preparing and using the same |
| EP0534988A1 (en) * | 1990-05-10 | 1993-04-07 | Cetus Corporation | Inhibitors of factor xii activation and applications thereof |
| EP0759556A3 (de) * | 1995-07-24 | 1998-05-20 | BEHRINGWERKE Aktiengesellschaft | Verfahren zur Quantifizierung aktivierter Faktoren |
| BR0317404A (pt) * | 2002-12-20 | 2005-11-16 | Axis Shield Diagnostics Ltd | Variantes do fator xiia |
| GB0500487D0 (en) * | 2005-01-11 | 2005-02-16 | Axis Shield Diagnostics Ltd | Forms of factor XIIa |
| GB0607515D0 (en) * | 2006-04-13 | 2006-05-24 | Axis Shield Diagnostics Ltd | Anti-factor xlla therapy |
| EP2548892A1 (en) | 2011-07-22 | 2013-01-23 | CSL Behring GmbH | Inhibitory anti-Factor XII/XIIa monoclonal Antibodies and their uses |
| RS66465B1 (sr) | 2011-07-22 | 2025-02-28 | Csl Behring Gmbh | Inhibitorna monoklonska antitela protiv faktora xii/xiia i njihove upotrebe |
| EP2623110A1 (en) | 2012-01-31 | 2013-08-07 | CSL Behring GmbH | Factor XII inhibitors for the treatment of neurological inflammatory disorders |
| US10286047B2 (en) | 2013-03-08 | 2019-05-14 | Csl Behring Gmbh | Treatment and prevention of remote ischemia-reperfusion injury |
| PL3013366T3 (pl) | 2013-06-28 | 2022-01-17 | Csl Behring Gmbh | Terapia skojarzona z zastosowaniem inhibitora czynnika xii i inhibitora c1 |
| DK3157548T3 (da) | 2014-06-18 | 2021-09-06 | Csl Behring Gmbh | Terapi anvendelse af en faktor xii-inhibitor i en neurotraumatisk sygdom |
| EP3240570B1 (en) | 2015-01-02 | 2025-09-24 | Takeda Pharmaceutical Company Limited | Bispecific antibodies against plasma kallikrein and factor xii |
| EA201890340A1 (ru) * | 2015-07-21 | 2018-09-28 | Дайэкс Корп. | Моноклональное антитело-ингибитор фактора xiia |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963657A (en) * | 1988-06-09 | 1990-10-16 | Temple University Of The Commonwealth System Of Higher Education | Monoclonal antibodies to the light chain region of human factor XII and methods of preparing and using the same |
-
1989
- 1989-01-27 GB GB898901859A patent/GB8901859D0/en active Pending
-
1990
- 1990-01-29 IL IL9320790A patent/IL93207A/en not_active IP Right Cessation
- 1990-01-29 JP JP2502992A patent/JP2916252B2/ja not_active Expired - Fee Related
- 1990-01-29 AU AU50305/90A patent/AU641912B2/en not_active Ceased
- 1990-01-29 DK DK90902656.9T patent/DK0455707T3/da active
- 1990-01-29 NZ NZ232273A patent/NZ232273A/en unknown
- 1990-01-29 AT AT90902656T patent/ATE121788T1/de not_active IP Right Cessation
- 1990-01-29 EP EP90902656A patent/EP0455707B1/en not_active Expired - Lifetime
- 1990-01-29 ES ES90902656T patent/ES2072423T3/es not_active Expired - Lifetime
- 1990-01-29 DE DE69018968T patent/DE69018968T2/de not_active Expired - Fee Related
- 1990-01-29 WO PCT/GB1990/000129 patent/WO1990008835A1/en not_active Ceased
- 1990-01-29 CA CA002045475A patent/CA2045475C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB8901859D0 (en) | 1989-03-15 |
| DE69018968T2 (de) | 1995-08-24 |
| DE69018968D1 (de) | 1995-06-01 |
| DK0455707T3 (da) | 1995-06-26 |
| EP0455707B1 (en) | 1995-04-26 |
| IL93207A (en) | 1994-02-27 |
| NZ232273A (en) | 1992-03-26 |
| AU641912B2 (en) | 1993-10-07 |
| IL93207A0 (en) | 1990-11-05 |
| AU5030590A (en) | 1990-08-24 |
| ATE121788T1 (de) | 1995-05-15 |
| EP0455707A1 (en) | 1991-11-13 |
| CA2045475A1 (en) | 1990-07-28 |
| WO1990008835A1 (en) | 1990-08-09 |
| JPH04503006A (ja) | 1992-06-04 |
| JP2916252B2 (ja) | 1999-07-05 |
| CA2045475C (en) | 2000-04-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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