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ES2071322T3 - Reduccion o prevencion de la irritacion de la piel por farmacos. - Google Patents

Reduccion o prevencion de la irritacion de la piel por farmacos.

Info

Publication number
ES2071322T3
ES2071322T3 ES91912369T ES91912369T ES2071322T3 ES 2071322 T3 ES2071322 T3 ES 2071322T3 ES 91912369 T ES91912369 T ES 91912369T ES 91912369 T ES91912369 T ES 91912369T ES 2071322 T3 ES2071322 T3 ES 2071322T3
Authority
ES
Spain
Prior art keywords
irritation
medicinal product
skin
human
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91912369T
Other languages
English (en)
Inventor
Michel J-N Cormier
Philip W Ledger
Alfred Amkraut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2071322T3 publication Critical patent/ES2071322T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Packaging For Recording Disks (AREA)
  • Passenger Equipment (AREA)

Abstract

LA PRESENTE INVENCION PRESENTA UN METODO PARA REDUCIR O PREVENIR LA IRRITACION DE UN MEDICAMENTO DE BASE DEBIL A BASE DE INHIBIR LA ACUMULACION DEL MEDICAMENTO EN LOS LISOSOMAS. EL MEDICAMENTO PRODUCE IRRITACIONES EN LOS SERES HUMANOS, ES DECIR, EL MEDICAMENTO ES SUSCEPTIBLE DE INDUCIR LA IRRITACION DE LA PIEL O DE LAS MUCOSAS EN UN SER HUMANO CUANDO SE ADMINISTRA TRANSDERMICAMENTE A LA PERSONA A UNA VELOCIDAD TERAPEUTICAMENTE EFECTIVA. LA REDUCCION O PREVENCION DE LA IRRITACION SE INDUCE MEDIANTE LA ADMINISTRACION EN LA PIEL O MUCOSA DEL SER HUMANO DE: A) UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE UN MEDICAMENTO DE BASE DEBIL QUE PRODUZCA IRRITACIONES EN LOS SERES HUMANOS, A UNA VELOCIDAD TERAPEUTICAMENTE EFECTIVA DURANTE UN PERIODO DE TIEMPO PREDETERMINADO; Y B) UNA CANTIDAD EFECTIVA DE UN AGENTE CAPAZ DE INHIBIR LA TOMA LISOSOMAL DEL MEDICAMENTO PARA REDUCIR O PREVENIR LA IRRITACION DE LA PIEL O LA MUCOSA.
ES91912369T 1990-07-06 1991-07-01 Reduccion o prevencion de la irritacion de la piel por farmacos. Expired - Lifetime ES2071322T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/549,584 US5130139A (en) 1990-07-06 1990-07-06 Reduction or prevention of skin irritation by drugs

Publications (1)

Publication Number Publication Date
ES2071322T3 true ES2071322T3 (es) 1995-06-16

Family

ID=24193593

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91912369T Expired - Lifetime ES2071322T3 (es) 1990-07-06 1991-07-01 Reduccion o prevencion de la irritacion de la piel por farmacos.

Country Status (18)

Country Link
US (1) US5130139A (es)
EP (1) EP0538302B1 (es)
JP (1) JP3224814B2 (es)
AT (1) ATE121627T1 (es)
AU (1) AU641787B2 (es)
CA (1) CA2046014C (es)
DE (1) DE69109292T2 (es)
DK (1) DK0538302T3 (es)
ES (1) ES2071322T3 (es)
FI (1) FI930038A0 (es)
GR (1) GR3015934T3 (es)
IE (1) IE74152B1 (es)
MX (1) MX9100042A (es)
NO (1) NO925038L (es)
NZ (1) NZ238804A (es)
PT (1) PT98177B (es)
WO (1) WO1992000746A1 (es)
ZA (1) ZA915067B (es)

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KR100228004B1 (ko) * 1991-11-08 1999-11-01 가마쿠라 아키오 살균성 점착제(粘着制)와 그 제조방법 및 점착제품과 그 응용
US5843979A (en) * 1993-02-25 1998-12-01 Bristol-Myers Squibb Company Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity
IL109036A (en) * 1993-03-19 1998-12-27 Cellegy Pharamaceuticals Inc Preparations for detachment of the epithelial barrier function and use of means for the preparation of such preparations
US6190894B1 (en) 1993-03-19 2001-02-20 The Regents Of The University Of California Method and compositions for disrupting the epithelial barrier function
US5451407A (en) * 1993-06-21 1995-09-19 Alza Corporation Reduction or prevention of skin irritation or sensitization during transdermal administration of a irritating or sensitizing drug
DK0752898T3 (da) 1994-03-30 1999-02-15 Alza Corp Mindskning af hudirritation ved elektrotransport-tilførsel
WO1995034262A1 (en) * 1994-06-16 1995-12-21 Department Of The Army, Us Government Transdermal treatment of malaria
US5686100A (en) * 1994-11-22 1997-11-11 E.R. Squibb & Sons, Inc. Prophylactic and therapeutic treatment of skin sensitization and irritation
WO1997047355A1 (en) * 1996-06-12 1997-12-18 Alza Corporation Reduction of skin sensitization in electrotransport drug delivery
US6512010B1 (en) * 1996-07-15 2003-01-28 Alza Corporation Formulations for the administration of fluoxetine
US5981168A (en) 1998-05-15 1999-11-09 The University Of British Columbia Method and composition for modulating amyloidosis
US6699497B1 (en) * 1998-07-24 2004-03-02 Alza Corporation Formulations for the transdermal administration of fenoldopam
US20040258742A1 (en) * 2003-04-11 2004-12-23 Van Osdol William Woodson Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
JP5254616B2 (ja) 2004-09-13 2013-08-07 クロノ セラピューティクス、インコーポレイテッド 生物学的同調性（ｂｉｏｓｙｎｃｈｒｏｎｏｕｓ）経皮的薬物送達
US20070042026A1 (en) * 2005-03-17 2007-02-22 Wille John J Prophylactic and therapeutic treatment of topical and transdermal drug-induced skin reactions
US8372040B2 (en) 2005-05-24 2013-02-12 Chrono Therapeutics, Inc. Portable drug delivery device including a detachable and replaceable administration or dosing element
WO2008092003A2 (en) 2007-01-25 2008-07-31 Honda Motor Co., Ltd. Vehicle systems control for improving stability
EP2729148A4 (en) 2011-07-06 2015-04-22 Parkinson S Inst COMPOSITIONS AND METHOD FOR THE TREATMENT OF SYMPTOMS IN PATIENTS WITH MORBUS PARKINSON
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
CA2900372C (en) * 2013-02-08 2021-06-08 Luoda Pharma Pty Ltd Methods of treating topical microbial infections
EP3250258A4 (en) 2015-01-28 2018-09-05 Chrono Therapeutics, Inc. Drug delivery methods and systems
WO2016145373A1 (en) 2015-03-12 2016-09-15 Chrono Therapeutics Inc. Craving input and support system
EP3565617A1 (en) 2017-01-06 2019-11-13 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
WO2019232077A1 (en) 2018-05-29 2019-12-05 Chrono Therapeutics Inc. Drug delivery methods and systems
CA3119992A1 (en) 2018-11-16 2020-05-22 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US4274420A (en) * 1975-11-25 1981-06-23 Lectec Corporation Monitoring and stimulation electrode
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4325367A (en) * 1977-06-13 1982-04-20 Robert Tapper Iontophoretic treatment apparatus
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
CA1153427A (en) * 1978-12-11 1983-09-06 Patrick T. Cahalan Tape electrode
WO1981000964A1 (en) * 1979-10-10 1981-04-16 Cyclotech Med Ind Pain blocking bandage
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US4314557A (en) * 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4419092A (en) * 1981-11-06 1983-12-06 Motion Control, Inc. Iontophoretic electrode structure
GB2124485B (en) * 1982-08-04 1986-06-04 Michael A Levy Penetrating topical medicament
US4559222A (en) * 1983-05-04 1985-12-17 Alza Corporation Matrix composition for transdermal therapeutic system
US4557723A (en) * 1983-08-18 1985-12-10 Drug Delivery Systems Inc. Applicator for the non-invasive transcutaneous delivery of medicament
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4573995A (en) * 1984-10-09 1986-03-04 Alza Corporation Transdermal therapeutic systems for the administration of naloxone, naltrexone and nalbuphine
US4702732A (en) * 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
FR2605221B1 (fr) * 1986-10-20 1989-09-01 Sanofi Sa Compositions pharmaceutiques ou veterinaires contenant de la de(hydroxymethyl)-25 deoxy-25 oxo-25 monensine
AU610839B2 (en) * 1986-11-07 1991-05-30 Purepac, Inc Transdermal administration of amines
US4983395A (en) * 1987-11-12 1991-01-08 Theratech Inc. Device for administering an active agent to the skin or mucosa
US4885154A (en) * 1988-03-01 1989-12-05 Alza Corporation Method for reducing sensitization or irritation in transdermal drug delivery and means therefor
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
US4908213A (en) * 1989-02-21 1990-03-13 Schering Corporation Transdermal delivery of nicotine
KR920702620A (ko) * 1989-06-19 1992-10-06 엠. 피. 잭슨 암치료에 유용하며 항히스타민성 특성을 갖는 약물

Also Published As

Publication number Publication date
NO925038L (no) 1993-01-06
NO925038D0 (no) 1992-12-30
CA2046014C (en) 2003-05-20
JP3224814B2 (ja) 2001-11-05
FI930038L (fi) 1993-01-05
FI930038A7 (fi) 1993-01-05
EP0538302A1 (en) 1993-04-28
IE912294A1 (en) 1992-01-15
MX9100042A (es) 1992-02-28
IE74152B1 (en) 1997-07-02
DE69109292D1 (de) 1995-06-01
AU641787B2 (en) 1993-09-30
WO1992000746A1 (en) 1992-01-23
AU8104691A (en) 1992-02-04
US5130139A (en) 1992-07-14
NZ238804A (en) 1992-08-26
CA2046014A1 (en) 1992-01-07
DK0538302T3 (da) 1995-09-18
PT98177B (pt) 1998-12-31
EP0538302B1 (en) 1995-04-26
GR3015934T3 (en) 1995-07-31
ZA915067B (en) 1992-04-29
PT98177A (pt) 1993-08-31
FI930038A0 (fi) 1993-01-05
DE69109292T2 (de) 1995-08-31
ATE121627T1 (de) 1995-05-15
JPH05508643A (ja) 1993-12-02

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