ES2062568T3 - Nuevos derivados de benzo (b) fenantrolinas-1,7 su preparacion y su aplicacion en terapeutica. - Google Patents
Nuevos derivados de benzo (b) fenantrolinas-1,7 su preparacion y su aplicacion en terapeutica.Info
- Publication number
- ES2062568T3 ES2062568T3 ES90917107T ES90917107T ES2062568T3 ES 2062568 T3 ES2062568 T3 ES 2062568T3 ES 90917107 T ES90917107 T ES 90917107T ES 90917107 T ES90917107 T ES 90917107T ES 2062568 T3 ES2062568 T3 ES 2062568T3
- Authority
- ES
- Spain
- Prior art keywords
- radical
- fenantrolinas
- therapeutics
- preparation
- application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000005605 benzo group Chemical group 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical compound [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- CFHIDWOYWUOIHU-UHFFFAOYSA-N oxomethyl Chemical compound O=[CH] CFHIDWOYWUOIHU-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NUEVOS DERIVADOS DE BENZO [B] FENANTROLINAS QUE CORRESPONDEN A LA FORMULA GENERAL (I), EN LA QUE: A REPRESENTA UN ATOMO DE NITROGENO O UN RADICAL ME-N ELEVADO +, R SUB 1 REPRESENTA, INDEPENDIENTEMENTE DE R SUB 2, UN RADICAL FORMILO (CHO), UN RADICAL DE FORMULA -CH SUB 2OR SUB 3, DONDE R SUB 3 ES UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO EN C SUB 1-C SUB 4, R SUB 2 REPRESENTA INDEPENDIENTEMENTE DE R SUB 1, UN RADICAL HIDROXILO, UN RADICAL DE FORMULA -NHR SUB 4 DONDE R SUB 4 ES UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO EN C SUB 1-C SUB 4 O R SUB 1 Y R SUB 2 JUNTOS REPRESENTAN UN RADICAL -CH SUB 2OCH SUB 2 N(R SUB 4)-, DONDE R SUB 4 ES UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO EN C SUB 1-C SUB 4, UN RADICAL -CH SUB 2 OCH SUB 2O-, ASI COMO LAS SALES ORGANICAS O MINERALES TERAPEUTICAMENTE ACEPTABLES DE ESTOS DERIVADOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR898914900A FR2654340B1 (fr) | 1989-11-14 | 1989-11-14 | Nouveaux derives de benzo [b] phenanthrolines-1,7 leur preparation et leur application en therapeutique. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2062568T3 true ES2062568T3 (es) | 1994-12-16 |
Family
ID=9387369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90917107T Expired - Lifetime ES2062568T3 (es) | 1989-11-14 | 1990-11-14 | Nuevos derivados de benzo (b) fenantrolinas-1,7 su preparacion y su aplicacion en terapeutica. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0502020B1 (es) |
| JP (1) | JPH05501562A (es) |
| AT (1) | ATE100809T1 (es) |
| DE (1) | DE69006366T2 (es) |
| DK (1) | DK0502020T3 (es) |
| ES (1) | ES2062568T3 (es) |
| FR (1) | FR2654340B1 (es) |
| WO (1) | WO1991007403A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9027111D0 (en) * | 1990-12-13 | 1991-02-06 | Raychem Ltd | Circuit protection device |
| FR2712290A1 (fr) * | 1993-11-10 | 1995-05-19 | Pf Medicament | Oxazino-acridines substituées, leur préparation et leur application en thérapeutique. |
| GB9517506D0 (en) * | 1994-12-16 | 1995-10-25 | Univ Cardiff | Benzophenanthrolines |
| DE102012006903B4 (de) * | 2012-04-05 | 2016-06-30 | Christian-Albrechts-Universität Zu Kiel | Neue aromatische Heterocyclen, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend neue aromatische Heterocyclen |
| CN111154481B (zh) * | 2020-01-06 | 2023-03-28 | 山东理工大学 | 用于检测去泛素化酶的纳米荧光探针的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ199887A (en) * | 1982-03-02 | 1985-03-20 | New Zealand Dev Finance | Phenanthroline derivatives and pharmaceutical compositions |
-
1989
- 1989-11-14 FR FR898914900A patent/FR2654340B1/fr not_active Expired - Fee Related
-
1990
- 1990-11-14 JP JP3500151A patent/JPH05501562A/ja active Pending
- 1990-11-14 DE DE69006366T patent/DE69006366T2/de not_active Expired - Fee Related
- 1990-11-14 AT AT90917107T patent/ATE100809T1/de not_active IP Right Cessation
- 1990-11-14 DK DK90917107.6T patent/DK0502020T3/da active
- 1990-11-14 ES ES90917107T patent/ES2062568T3/es not_active Expired - Lifetime
- 1990-11-14 EP EP90917107A patent/EP0502020B1/fr not_active Expired - Lifetime
- 1990-11-14 WO PCT/FR1990/000811 patent/WO1991007403A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| FR2654340B1 (fr) | 1994-03-04 |
| FR2654340A1 (fr) | 1991-05-17 |
| EP0502020A1 (fr) | 1992-09-09 |
| DK0502020T3 (da) | 1994-05-09 |
| DE69006366D1 (de) | 1994-03-10 |
| JPH05501562A (ja) | 1993-03-25 |
| DE69006366T2 (de) | 1994-08-11 |
| ATE100809T1 (de) | 1994-02-15 |
| EP0502020B1 (fr) | 1994-01-26 |
| WO1991007403A1 (fr) | 1991-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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