ES2057128T3 - Procedimiento para medir endotoxinas. - Google Patents
Procedimiento para medir endotoxinas.Info
- Publication number
- ES2057128T3 ES2057128T3 ES89306795T ES89306795T ES2057128T3 ES 2057128 T3 ES2057128 T3 ES 2057128T3 ES 89306795 T ES89306795 T ES 89306795T ES 89306795 T ES89306795 T ES 89306795T ES 2057128 T3 ES2057128 T3 ES 2057128T3
- Authority
- ES
- Spain
- Prior art keywords
- endotoxin
- procedure
- test sample
- gelation reaction
- measuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002158 endotoxin Substances 0.000 title abstract 5
- 238000001879 gelation Methods 0.000 abstract 2
- 241001529572 Chaceon affinis Species 0.000 abstract 1
- 210000003677 hemocyte Anatomy 0.000 abstract 1
- 229940000351 hemocyte Drugs 0.000 abstract 1
- 239000006166 lysate Substances 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 238000012421 spiking Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56916—Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
PUEDE DETERMINARSE UNA CONCENTRACION DE ENDOTOXINAS EN UNA MUESTRA DE COMPROBACION MIDIENDO LOS CAMBIOS OPTICOS ORIGINADOS POR UNA REACCION DE CONGELACION QUE SE CREA HACIENDO REACCIONAR EL RESULTADO DE LA LISIS DEL HEMOCITO DE UN LIMULO CON LA ENDOTOXINA SIN INFLUENCIA DE SUSTANCIAS AFECTANTES, AÑADIENDO AL MENOS TRES CANTIDADES CONOCIDAS DIFERENTES DE ENDOTOXINA A UN AMUESTRA DE COMPROBACION Y UNA SOLUCION SIN ENDOTOXINAS NI INFLUENCIA EN LA REACCION DE CONGELACION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16706888 | 1988-07-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2057128T3 true ES2057128T3 (es) | 1994-10-16 |
Family
ID=15842811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89306795T Expired - Lifetime ES2057128T3 (es) | 1988-07-05 | 1989-07-04 | Procedimiento para medir endotoxinas. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0350273B1 (es) |
| JP (1) | JPH07113643B2 (es) |
| AT (1) | ATE108558T1 (es) |
| DE (1) | DE68916714T2 (es) |
| ES (1) | ES2057128T3 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5648230A (en) * | 1994-06-30 | 1997-07-15 | Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) | Endotoxin stabilizing agent, endotoxin composition and method for assaying endotoxin |
| WO2003093323A2 (en) * | 2002-04-30 | 2003-11-13 | Biowhittaker Technologies, Inc. | Automated sequential injection analysis systems for the determination of trace endotoxin levels |
| EP2261642A4 (en) * | 2008-03-19 | 2011-10-26 | Toru Obata | DEVICE FOR DETECTING HORIZONTAL FORMATION |
| US9658218B2 (en) * | 2012-05-07 | 2017-05-23 | Siemens Healthcare Diagnostics Inc. | Determination of total analyte concentration |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1040081A (en) * | 1974-05-01 | 1978-10-10 | Baxter Travenol Laboratories | Method for analysis of endotoxin-precipitated limulus lysate |
| US4038029A (en) * | 1976-01-20 | 1977-07-26 | Worthington Biochemical Corporation | Limulus lysate turbidity test for pyrogens |
| EP0347951B1 (en) * | 1984-06-27 | 1993-08-04 | Wako Pure Chemical Industries, Ltd. | Apparatus for measuring endotoxin |
| JPS62110153A (ja) * | 1985-04-03 | 1987-05-21 | Wako Pure Chem Ind Ltd | エンドトキシン定量方法 |
-
1989
- 1989-07-04 ES ES89306795T patent/ES2057128T3/es not_active Expired - Lifetime
- 1989-07-04 EP EP89306795A patent/EP0350273B1/en not_active Expired - Lifetime
- 1989-07-04 DE DE68916714T patent/DE68916714T2/de not_active Expired - Fee Related
- 1989-07-04 AT AT89306795T patent/ATE108558T1/de not_active IP Right Cessation
- 1989-07-05 JP JP1173693A patent/JPH07113643B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02124466A (ja) | 1990-05-11 |
| JPH07113643B2 (ja) | 1995-12-06 |
| EP0350273A3 (en) | 1990-10-10 |
| ATE108558T1 (de) | 1994-07-15 |
| EP0350273A2 (en) | 1990-01-10 |
| DE68916714D1 (de) | 1994-08-18 |
| EP0350273B1 (en) | 1994-07-13 |
| DE68916714T2 (de) | 1995-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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