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EP4622720A1 - Utilisation d'une composition pour fournir de l'énergie luminescente sur la peau - Google Patents

Utilisation d'une composition pour fournir de l'énergie luminescente sur la peau

Info

Publication number
EP4622720A1
EP4622720A1 EP23800813.0A EP23800813A EP4622720A1 EP 4622720 A1 EP4622720 A1 EP 4622720A1 EP 23800813 A EP23800813 A EP 23800813A EP 4622720 A1 EP4622720 A1 EP 4622720A1
Authority
EP
European Patent Office
Prior art keywords
composition
vitamin
skin
derivative
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP23800813.0A
Other languages
German (de)
English (en)
Inventor
Mohini Anand Bapat
Anita DAMODARAN
Naresh Dhirajlal Ghatlia
Amitabha Majumdar
Gouri Gupchup MALHOTRA
Mruthyunjaya Swamy MATHAPATHI
Simone SETHNA
Satish Kumar VENKATESH
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unilever Global IP Ltd
Unilever IP Holdings BV
Original Assignee
Unilever Global IP Ltd
Unilever IP Holdings BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Global IP Ltd, Unilever IP Holdings BV filed Critical Unilever Global IP Ltd
Publication of EP4622720A1 publication Critical patent/EP4622720A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations

Definitions

  • the present invention relates to use of a composition that provides energizing glow to skin. It more particularly relates to a topical application that delivers a fresh, young and lively look to skin that has a glowing appearance.
  • Energizing brightness is another one of the benefits that some products in the market have been providing. Energizing brightness means that the skin gets a fresh and young look, with a lively appearance, which recharges the skin and helps protect against external and internal stresses.
  • actives available in the market that are claimed to deliver this benefit e.g. Oli’VineTM ST a product sold by Gattefosse. It has the INCI name Water (and) Olivine Extract. It has been shown that use of such actives increases ATP (adenosine triphosphate) levels and reduces intracellular oxidation which are the key processes that deliver the claimed benefits to the skin.
  • the present inventors in wishing to deliver such a benefit with known and commonly available ingredients that are safe and are inexpensive, have hit upon a unique combination of vitamins at very low concentrations which surprisingly works even when incorporated in cleansing compositions. They have found that a combination of vitamin C and vitamin E when used at as low a concentration as less than 20 ppm in a wash off composition work synergistically to provide energizing glow to skin as evidenced by the resultant ATP levels. The present inventors are not aware of any published information which implicates either of these actives for providing enhanced ATP levels. Thus, it was indeed surprising to the inventors that a combination of two actives, neither of which is known for enhancing ATP levels are capable of delivering energizing glow to skin by interacting synergistically. It was further surprising that this could be achieved at incorporation of very low concentration of less than 20 ppm, that too in a wash-off composition.
  • Sodium ascorbyl phosphate is an active stable vitamin C derivative ingredient for the cosmetics industry. It liberates vitamin C in the skin and protects the cells of the skin, promotes collagen formation, controls the formation of senile keratosis, and lightens dark skin.
  • 3-O-ethyl ascorbic acid promotes the production of collagen, which significantly improves the structure of the skin cells and the overall condition of skin.
  • Magnesium ascorbyl phosphate has all the functions of vitamin C and is very stable. It has excellent anti-oxidation and protection benefits, and can effectively resist UV radiation and promotes collagen production. This product is recommended for skin whitening/lightening applications, as well as anti-aging and anti-wrinkle products.
  • Vitamin C L-ascorbic acid
  • USP is an active form of vitamin C as it occurs naturally. It is a potent antioxidant (shown to be able to protect skin from oxidative damages). It can improve appearance of aged and fragile skin. Widely used as add-on ingredient in skin-lightening products to correct hyperpigmentation and age spots.
  • Ascorbyl glucoside is a water-soluble Vitamin C derivative with superior stability. It resists degradation, and has the same lightening, sun protective and anti-aging properties as ascorbic acid.
  • Tetrahexyldecyl ascorbate is a very stable, oil-soluble Vitamin C ester but has no inherent capabilities as an antioxidant because all hydroxyl groups are esterified.
  • Vitamin C or its derivative is preferably included in 0.00001 to 0.002%, more preferably 0.0001 to 0.0015% by weight of the composition.
  • Alpha-tocopheryl acetate also known as tocopheryl acetate, is a synthetic form of vitamin E.
  • a- tocopheryl acetate is a fat-soluble vitamin E and considered the most stable and active form of vitamin E.
  • Alpha tocopheryl acetate is known for its antioxidant properties and it protects cells from oxidative stress induced damages.
  • Tocopheryl acetate can be found in many skincare products where it is used as a skinconditioning agent. Its antioxidant effect helps in preventing skin damages caused by excessive exposure to ultraviolet (UV) radiation emitted by the sun. This product is recommended for skin whitening/lightening applications, as well as anti-aging and anti-wrinkle products.
  • UV ultraviolet
  • D a-Tocopherol succinate is a fat-soluble vitamin and one of the most potent antioxidant tocopherol. Its antioxidant property helps in reducing oxidative stress induced damages in cells.
  • the cleansing composition of the invention may also be delivered through a moisturizing bar or a moisturizing liquid composition.
  • Moisturizing bar compositions comprising fatty acyl isethionates (e.g. cocyl isethionate) are especially preferred.
  • Fatty acyl isethionates e.g., cocoyl isethionates
  • surfactant "products" are defined as mixtures of anionic acyl isethionate surfactants and fatty acids/fatty acid soaps. They are highly desirable in personal care skin or hair cleansing products, particularly in personal care products, because they lather well, are mild to the skin and have good emollient properties.
  • Wash-off composition in the form of a liquid generally comprises surfactants at low concentration and are mild on skin.
  • the surfactant is generally included in 4 to 18%, preferably 6 to 12% by weight of the liquid cleansing composition.
  • Surfactants for inclusion in the liquid cleansing composition of the invention may preferably be of the anionic, non-ionic, cationic or amphoteric types.
  • a useful surfactant for inclusion in the liquid cleansing composition of the invention is sodium lauryl ether sulphate (SLES).
  • SLES for use in the present invention generally preferably has 1 to 3 Ethoxylate (EO) groups.
  • SLES is preferably included in 3 to 8% by weight of the composition.
  • the other surfactant which may be included in the present invention is cocoamide monoethanol amine (CMEA).
  • Water is a preferred carrier in liquid cleansing compositions of the invention.
  • water is generally present in 70 to 95% by weight.
  • the composition may also additionally comprise a free fatty acid other than hydroxy stearic acid.
  • the free fatty acid is preferably included in 0.01 to 5% by weight of the composition.
  • the free fatty acid may be one or more of C8-C24, preferably C10-C20 and most preferably C12-C18 fatty acid.
  • the free fatty acids can exist as unsaponified fatty acids in the final product.
  • Preferred liquid cleansing compositions may include other known ingredients such as electrolytes, perfumes, pigments, preservatives, emollients, sunscreens, emulsifiers, gelling agents and thickening agents.
  • the method is preferably cosmetic or non-therapeutic.
  • Yet another aspect of the present invention relates to use of a combination of vitamin C or its derivative and Vitamin E or its derivative to boost ATP levels in HDFa cells.
  • vitamin C or its derivative is selected from the group comprising ascorbic acid, salts of ascorbic acid, oxidized and reduced forms of vitamin C, sodium ascorbyl phosphate, 3-0-Ethyl ascorbic acid, ascorbyl methylsilanol pectinate, magnesium ascorbyl phosphate, ascorbyl glucoside, tetrahexyldecyl ascorbate, aminopropyl ascorbyl phosphate, ascorbyl Palmitate, and mixtures thereof; and wherein vitamin E or its derivative selected from the group comprising a-,p-,y-, and o- tocopherols, their related corresponding tocotrienols and mixtures thereof.
  • vitamin C or its derivative is included in 0.00001 to 0.002% by weight of the composition.
  • vitamin E or its derivative is included in 0.00001 to 0.002% by weight of the composition.
  • composition additionally comprises 0.001 to 1 wt% hydroxy stearic acid.
  • hydroxystearic acid is 12-hydroxystearic acid.
  • composition is a cleansing composition comprising a surfactant.
  • the surfactant comprises an anionic surfactant preferably soap.
  • composition comprises a humectant preferably glycerol.
  • the present invention provides a cleansing composition
  • a cleansing composition comprising
  • the composition additionally comprises a humectant preferably glycerol.
  • the present invention provides a method increase adenosine triphosphate (ATP) levels in the skin comprising the steps of (i) applying a composition as claimed in any one of the preceding claims 10 to 13 on to said skin preferably diluted with water, followed by (ii) rinsing said skin with water.
  • ATP adenosine triphosphate
  • the ATP levels as measured are also shown in Table -1 .
  • Table -1 The data in Table - 1 above indicates that the combination of Vitamin C and Vitamin E at any concentration (from 0.01 to 1 ppm) is superior to that of using an individual active at the same concentration, thereby indicating synergistic activity.
  • a cleaning composition as given in Table -2 below was found to be useful for delivering the energizing glow by way of the present invention.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne l'utilisation d'une composition qui fournit de l'énergie luminescente à la peau. Elle concerne plus particulièrement une application topique qui délivre un aspect frais, jeune et vivant à la peau qui a un aspect brillant. La présente invention a été obtenue par l'utilisation d'une composition qui comprend une combinaison de vitamine C et de vitamine E. La présente invention a été trouvée efficace même lorsqu'elle est administrée par l'intermédiaire d'une composition de nettoyage.
EP23800813.0A 2022-11-24 2023-11-02 Utilisation d'une composition pour fournir de l'énergie luminescente sur la peau Pending EP4622720A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP22209344 2022-11-24
PCT/EP2023/080541 WO2024110164A1 (fr) 2022-11-24 2023-11-02 Utilisation d'une composition pour fournir de l'énergie luminescente sur la peau

Publications (1)

Publication Number Publication Date
EP4622720A1 true EP4622720A1 (fr) 2025-10-01

Family

ID=84361891

Family Applications (1)

Application Number Title Priority Date Filing Date
EP23800813.0A Pending EP4622720A1 (fr) 2022-11-24 2023-11-02 Utilisation d'une composition pour fournir de l'énergie luminescente sur la peau

Country Status (5)

Country Link
EP (1) EP4622720A1 (fr)
JP (1) JP2025536779A (fr)
CN (1) CN120265270A (fr)
MX (1) MX2025005944A (fr)
WO (1) WO2024110164A1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2460054B (en) 2008-05-14 2010-11-24 Nb Labs Ltd A skin anti-aging formulation
CA2813328C (fr) 2010-11-11 2017-09-12 Unilever Plc Compositions revitalisantes pour la peau sans rincage a l'etat non solide contenant de l'acide 12-hydroxystearique
WO2014041528A2 (fr) * 2012-09-14 2014-03-20 Martin Roslain Margaret Composition
JP2020519642A (ja) 2017-05-12 2020-07-02 シャクリー コーポレイション 美容利用のための局所マスカダイン配合物
US11185492B2 (en) 2018-12-14 2021-11-30 Mary Kay Inc. Cosmetic compositions

Also Published As

Publication number Publication date
JP2025536779A (ja) 2025-11-07
MX2025005944A (es) 2025-06-02
CN120265270A (zh) 2025-07-04
WO2024110164A1 (fr) 2024-05-30

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