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EP4615571A1 - Cylindre rotatif - Google Patents

Cylindre rotatif

Info

Publication number
EP4615571A1
EP4615571A1 EP23805671.7A EP23805671A EP4615571A1 EP 4615571 A1 EP4615571 A1 EP 4615571A1 EP 23805671 A EP23805671 A EP 23805671A EP 4615571 A1 EP4615571 A1 EP 4615571A1
Authority
EP
European Patent Office
Prior art keywords
catheter
transducer
ultrasound transducer
longitudinal axis
self
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP23805671.7A
Other languages
German (de)
English (en)
Inventor
Liang ZHAI
Richard A. Bautista
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Medical Devices Co Ltd
Original Assignee
Otsuka Medical Devices Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Medical Devices Co Ltd filed Critical Otsuka Medical Devices Co Ltd
Publication of EP4615571A1 publication Critical patent/EP4615571A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A61N7/022—Localised ultrasound hyperthermia intracavitary
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00184—Moving parts
    • A61B2018/00202—Moving parts rotating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
    • A61B2018/00279—Anchoring means for temporary attachment of a device to tissue deployable
    • A61B2018/00285—Balloons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00404—Blood vessels other than those in or around the heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00505—Urinary tract
    • A61B2018/00511—Kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0004—Applications of ultrasound therapy
    • A61N2007/0021—Neural system treatment
    • A61N2007/003—Destruction of nerve tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0043—Ultrasound therapy intra-cavitary

Definitions

  • This application relates generally to ultrasonic transducers and in particular, self-rotating ultrasonic transducers.
  • High blood pressure also known as hypertension
  • hypertension commonly affects adults. Left untreated, hypertension can result in renal disease, arrhythmias, and heart failure. Treatment of hypertension has focused on interventional approaches to inactivate the renal nerves surrounding a renal artery.
  • Intraluminal devices such as catheters, may reach specific structures, such as the renal nerves, that are proximate to the lumens in which the catheters travel. Accordingly, catheter-based systems can deliver energy from within the lumens to inactivate the renal nerves in the vessel walls.
  • a uniform lesion around the body lumen, e.g., a vessel wall is desired to achieve optimal nerve inactivation at different locations around the vessel wall.
  • An ultrasound transducer with a large surface area can be used to transmit a sufficient amount of power in a short period of time to ensure uniform energy distribution.
  • this solution encounters demanding manufacturing requirements.
  • Rotating the ultrasound transducer around the body lumen using a preloaded spring/coil, guidewire, micromotor or using the ultrasound transducer as an actuator are methods to achieve circumferential ablation.
  • these methods require an additional motor to be used with the ultrasound transducer.
  • a catheter comprising a catheter shaft and a self-rotating ultrasound transducer positioned along a longitudinal axis on a distal region of the catheter shaft, the self-rotating ultrasound transducer having a shape wherein the self-rotating ultrasound transducer is configured to self-rotate around the longitudinal axis when an acoustic radiation force generates a net momentum from reactive forces from a surrounding environment that has a net non-zero torque around a rotation axis of the self-rotating ultrasound transducer.
  • a catheter comprising a catheter shaft and a self-rotating ultrasound transducer positioned along a longitudinal axis on a distal region of the catheter shaft, the self-rotating ultrasound transducer having a surface acoustic intensity distribution, wherein the self-rotating ultrasound transducer is configured to self-rotate around the longitudinal axis when an acoustic radiation force generated due to acoustic transmission from the self-rotating ultrasound transducer thereby generates a net momentum from reactive forces from a surrounding environment that has a net non-zero torque around a rotation axis of the self-rotating ultrasound transducer.
  • a catheter comprising a transducer positioned along a longitudinal axis on a distal region of a catheter shaft, a fixture for mounting the transducer, wherein the fixture is mounted off-centered whereby the transducer self-rotates around the fixture when an acoustic radiation force generated due to acoustic transmission from the transducer thereby generates a net momentum from reactive forces from a surrounding environment that has a net non-zero torque around a rotation axis of the transducer.
  • a catheter comprising a transducer having a shape that self-rotates about a post positioned along a longitudinal axis on a distal region of a catheter shaft, a first and second ring arranged on each side of the transducer, wherein each ring comprises at least one leg and at least one of the rings is coupled to an ID of the transducer, and a third ring coupled to an OD of the transducer, the third ring located at a same end of the transducer where at least one of the rings is coupled to the ID of the transducer, and wherein the post is mounted off-centered causing the transducer to self-rotate around the post when an acoustic radiation force generated due to acoustic transmission from the transducer thereby generates a net momentum from reactive forces from a surrounding environment that has a net non-zero torque around a rotation axis of the ultrasound transducer.
  • a catheter comprising a catheter shaft and an ultrasound transducer positioned along a longitudinal axis on a distal region of the catheter shaft, wherein a cross-sectional shape of the transducer perpendicular to the longitudinal axis is asymmetrical about a rotation axis of the transducer.
  • a catheter comprising a catheter shaft and an ultrasound transducer positioned along a longitudinal axis on a distal region of the catheter shaft, wherein in a non-rotating state, a direction in which acoustic radiation forces are transmitted from a surface of the ultrasound transducer is less than 360 degrees with respect to a longitudinal axis of the ultrasound transducer.
  • a catheter comprising a catheter shaft and an ultrasound transducer rotatably positioned along a longitudinal axis on a distal region of the catheter shaft, wherein the ultrasound transducer has a transducer surface and is configured for a transfer of an acoustic momentum from the transducer surface to a fluid surrounding the transducer to generate an acoustic radiation force that pushes the fluid away from the transducer and causes a net non-zero torque acting on the transducer around the longitudinal axis.
  • the catheter may be configured as generally presented herein.
  • a method of operating a catheter comprising a catheter shaft and an ultrasound transducer rotatably positioned along a longitudinal axis on a distal region of the catheter shaft, wherein the ultrasound transducer has a transducer surface
  • the method comprises energizing the ultrasound transducer to transfer an acoustic momentum from the transducer surface to a fluid surrounding the transducer to generate an acoustic radiation force that pushes the fluid away from the transducer and causes a net non- zero torque that rotates the transducer around the longitudinal axis.
  • the method may comprise one or more further steps as presented herein.
  • FIG. 1 illustrates an ultrasound-based tissue treatment system, in accordance with an embodiment.
  • FIG. 2 illustrates a perspective view of selected components of the ultrasound-based tissue treatment system introduced in FIG. 1 , inserted into a body lumen, in accordance with an embodiment.
  • FIG. 3 illustrates a longitudinal cross-sectional view of a distal portion of a catheter of an ultrasound-based tissue treatment system, in accordance with an embodiment.
  • FIG. 4 illustrates acoustic radiation force based self-rotation of a spiral-shaped transducer, in accordance with an embodiment.
  • FIG. 5A illustrates a perspective view of a spiral-shaped transducer, in accordance with an embodiment.
  • FIG. 5B illustrates a cross-sectional view of a spiral-shaped transducer shown in FIG.
  • FIG. 6 illustrates a cross-sectional view of a transducer experiencing rotational momentum generated by acoustic radiation force, in accordance with an embodiment.
  • FIG. 7 illustrates a perspective view of a spiral-shaped transducer rotating about a post, in accordance with an embodiment.
  • FIG. 8 illustrates a detail view of the spiral-shaped transducer in FIG. 7, in accordance with an embodiment.
  • a self-rotating ultrasound transducer around a vessel center axis can uniformly ablate tissue around a vessel.
  • the transducer simultaneously heats the surrounding tissues uniformly because of the self-rotating mechanism. It is not necessary for the transducer to have a cylindrical or tube shape to be able to deliver cylindrical ablation to the tissues around the vessel because of the self-rotating mechanism.
  • the ultrasound transducer can be a regular or irregular shape or the ultrasound transducer can be a regular or irregular polygon (e.g., rectangular, triangular, parallelogram, hexagon, square, pentagon, quadrilateral, or ellipse), oval or asymmetrical shape in cross-section perpendicular to the longitudinal axis.
  • the ultrasound transducer can be an enclosed or non-enclosed shape in cross-section perpendicular to the longitudinal axis.
  • the surface acoustic intensity distribution can also cause a transducer to self-rotate.
  • a larger surface area is typically desired within the application geometry constraints to maximize the energy transfer rate or power output.
  • the rotation speed of the self-rotating ultrasound transducer can be controlled by the transducer geometries and ablation power. These controls can be applied to enhance lesion uniformity.
  • FIG. 1 illustrates features of an ultrasound-based tissue treatment system 100, in accordance with an embodiment.
  • an ultrasound-based tissue treatment system is shown in accordance with an embodiment.
  • the tissue treatment system 100 is shown as including a catheter 102, a controller 120, and a connection cable 140.
  • the system 100 further includes an ultrasound transducer within a balloon 112, a reservoir 110, a fluid transfer cartridge 130, and a control mechanism, such as a handheld remote control.
  • a control mechanism such as a handheld remote control.
  • the controller 120 is shown as being connected to the catheter 102 through the cartridge 130 and the connection cable 140. In certain embodiments, the controller 120 interfaces with the cartridge 130 to provide a cooling fluid to the catheter 102 for selectively inflating and deflating the balloon 112.
  • the balloon 112 can be made from, e.g., nylon, a polyimide film, a thermoplastic elastomer (such as those marked under the trademark PEBAXTM), a medical-grade thermoplastic polyurethane elastomer (such as Pellethane®, Isothane®, or other suitable polymers or any combination thereof), but is not limited thereto.
  • the ultrasound transducer 111 may be disposed partially or completely within the balloon 112, which may be inflated with a cooling fluid 403 so as to contact the interior surface (e.g., intima) of the body lumen.
  • the ultrasound transducer 111 may be used to output an acoustic signal when the balloon 112 fully occludes a body lumen of a target vessel 200.
  • the balloon 112 may center the ultrasound transducer 111 within the body lumen.
  • the balloon 112 is inflated while inserted in the body lumen of the patient during a procedure at a working pressure of about 10 to about 30 psi using the cooling fluid 403.
  • the balloon 112 may be or include a compliant, semi-compliant or non -compliant medical balloon.
  • the balloon 112 is sized for insertion in the body lumen and, in the case of insertion into the renal artery, for example, the balloon 112 may be selected from available sizes including outer diameters of 3.5, 4.2, 5, 6, 7, or 8 mm, but not limited thereto.
  • the outer wall of the balloon 112 when inflated by being filled with the cooling fluid 403 under the control of the controller 120, the outer wall of the balloon 112 may be generally parallel with the outer surface of the ultrasound transducer 111.
  • the balloon 112 may be inflated sufficiently as to be in apposition with the body lumen.
  • the balloon 112 when inflated, may at least partially contact, and thus be in apposition with, an inner surface of a vessel wall 450 of the body lumen.
  • the balloon 112 can substantially stop blood within the body lumen from following past the balloon.
  • the balloon 112 is configured not to contact the body lumen when expanded.
  • the balloon 112 may surround the ultrasound transducer 111 in order to cool the ultrasound transducer 111 during sonications, but the balloon may not contact or occlude the body lumen, and the blood within the body lumen may be relied upon to cool the body lumen instead of the cooling fluid.
  • the balloon 112 may be non-compliant.
  • the balloon 112 comprises nylon.
  • the non-compliant balloon (e.g., 112) can act as the centering mechanism.
  • the cooling of the vessel wall can be managed by a cooling system of the generator by flowing water or other cooling fluid, such as dextrose or saline, through the balloon if necessary.
  • a non-compliant balloon advantageously offers tighter control of balloon design.
  • the non-compliant balloon (e.g., 112) may be advantageously constructed such that the balloon surface, which is without wrinkles when under inflation, does not interfere with sonication, and holds the desired shape. Additionally, or alternatively, the balloon 112 may be maintained at a specified size by pushing cooling fluid through and/or pulling cooling fluid out of the balloon 112 at a specified flow rate.
  • the ultrasound transducer 111 is mounted on a distal tip of a catheter 102 without a balloon.
  • the blood flow provides cooling for both the transducer 111 and the vessel wall.
  • the ultrasound transducer 111 may include a cylindrical hollow tube made of a piezoelectric material (e.g., lead zirconate titanate (PZT), etc.), with inner and outer electrodes 502, 504 disposed on the inner and outer surfaces of the cylindrical tube, respectively.
  • a cylindrical hollow tube of piezoelectric material is an example of, and thus can be referred to as, a piezoelectric ultrasound transducer body.
  • the piezoelectric ultrasound transducer body can have various other shapes and need not be hollow.
  • the piezoelectric ultrasound transducer body can comprise a groove or a slot.
  • the piezoelectric material, of which the piezoelectric ultrasound transducer body is made is lead zirconate titanate 8 (PZT8), which is also known as Navy III Piezo Material.
  • Raw PZT ultrasound transducers may be plated with layers of copper, nickel and/or gold to create electrodes on surfaces (e.g., the inner and outer surfaces) of the piezoelectric ultrasound transducer body.
  • Application of a voltage and alternating current across inner and outer electrodes 502, 504 causes the piezoelectric material to vibrate transverse to the longitudinal direction of the cylindrical tube and radially emit ultrasonic waves.
  • the ultrasound transducer 111 can be positioned within an interior 506 of the balloon 112.
  • the balloon 112 can have the interior 506 in fluid communication with a fluid lumen 508 of the catheter shaft 214.
  • the fluid lumen 508 can convey cooling fluid 403 into the interior 506 to cool the ultrasound transducer 111.
  • the balloon 112 can contain the ultrasound transducer 111 within the interior 506 such that the ultrasound transducer 111 is contacted and cooled by cooling fluid 403 that passes into the interior 506 from the fluid lumen 508. In other embodiments, there is no balloon 112 and the ultrasound transducer 111 is positioned in the body lumen.
  • the ultrasound transducer 111 can be generally supported via a backing member or post 507.
  • the backing member 507 comprises stainless steel coated with nickel and gold, wherein nickel is used as a bonding material between the stainless steel and gold plating.
  • the range of the outer diameter of the ultrasound transducer 111 is about 1 - 5 mm. In certain embodiments suitable, e.g., for renal denervation, an outer diameter of the ultrasound transducer 111 is about 1.5 mm, an inner diameter of the ultrasound transducer 111 is about 1 mm, and the ultrasound transducer 111 has a length of about 6 mm.
  • Ultrasound transducers 111 having other inner diameters, outer diameters, and lengths, and more generally dimensions and shapes, are also within the scope of the embodiments described herein. Further, it is noted that the drawings in the figures are not necessarily drawn to scale, and often are not drawn to scale.
  • FIG. 5B illustrates a cross-sectional view of a spiral-shaped ultrasound transducer 111 shown in FIG. 5A, in accordance with an embodiment.
  • the backing material 614 can be air or water.
  • a post 514 is a mounting piece/fixture and used to hold the ultrasound transducer 111.
  • the post 514 is positioned along the longitudinal axis 300.
  • the longitudinal axis 300 can comprise a rolling bearing.
  • the rolling bearing can be balls, cylindrical rollers, spherical rollers, tapered rollers, or needle rollers.
  • the rolling bearing can comprise rotating electrical contacts to cause electrical current to be passed between two mechanical components, one of which is rotationally movable in relation to the other. These mechanisms can be a carbon brush bearing, slip ring, or inductive coupling. When the rotary component is supported by a rolling bearing, the rotating electrical contacts are generally assemblies separated and insulated electrically from the rolling bearing (See FIG. 8).
  • the post 514 in FIG. 5B can be mounted in any location for the ultrasound transducer 111 to self-rotate, so long as the post 514 is not mounted in the center (i.e., off-the-center mount).
  • FIG. 6 there are radial lines passing the rotation axis.
  • FIG. 6 also illustrates the normal direction of the ultrasound transducer 111 surface. Assuming (r, 0) is the position of any point on the transducer outer surface, y is the angle between the radial line and surface normal vector, P is the total power, I is the temporal average spatial intensity, and c is the speed of sound, thus:
  • the rate of radius increase is:
  • the ultrasound transducer 111 During acoustic transmission, the ultrasound transducer 111 generates an acoustic radiation force, which pushes the fluid away from the surface along the surface normal.
  • FIG. 7 illustrates a perspective view of a spiral-shaped transducer 111 rotating about a post 514, in accordance with an embodiment.
  • the transducer 111 rotates about the post 514 using rings 604a, 604b, and 610.
  • Ring 604a comprises bearings, such as ring bearings, to allow the transducer 111 to rotate about the post 514 and the ring 604a holds the post 514 in place.
  • Ring 604a is soldered to the ID. There exist no electrical connections at ring 604a.
  • the rings 610, 604a, 604b can be made of low-friction, relatively hard materials (e.g., Teflon, Ruland gold, diamond coated) so that it can easily rotate about the post 514.
  • the post 514 can be coated with Teflon.
  • Ring 604b is connected to the ID as shown in FIG. 8 and rotates about the post 514.
  • the rotational momentum (M) pushes the ultrasound transducer 111 to rotate.
  • the spiral parameter y and the transducer radius are geometric design parameters that impact the generation of momentum.
  • Power (P) can be used to control rotational acceleration and speed.
  • Ring 610 rotates about the post 514 because it is connected by at least one wire to the transducer 111 OD (as shown in FIG. 8). Wires 602a, 602b can be embedded in the post 514 and connect rings 604b, 610 to the main coax or cable.
  • FIG. 8 illustrates a detail view of the spiral-shaped transducer in FIG. 7, in accordance with an embodiment.
  • Ring 604b comprises legs 608, which are connected to the transducer 111 by soldering or conductive epoxy.
  • one leg 608 can be used, so long as the rings 604a, 604b holds the transducer 111 in place for rotation and provides mechanical stability.
  • the legs 608 are different lengths and are not necessarily equal to the width of the PZT transducer 111.
  • the legs 608 gives the rings 604a, 604b its rotational motion because it creates a deviation from the central axis (i.e., off-the -center mount).
  • Ring 610 is a slip ring comprising a bearing, such as a ring bearing.
  • ring 604b can make contact to wire 602a and ring 610 can make contact to wire 602b.
  • Ring 610 is also soldered to the outer surface of the transducer 111.
  • Ring 610 has an OD electrical connection via wire 602c.
  • Ring 606 is a washer and acts as an insulator.
  • Ring 604b is a slip ring comprising a bearing, such as a ring bearing.
  • rings 604b, 610 comprise a slip-ring configuration, having brushes made of carbon materials and slip-ring bodies, wherein the brushes are electrically conductively connected to slip rings of the slip-ring bodies.
  • the slip rings can be formed of metals such as copper or copper alloys such as, for example, bronze, tin bronzes, nickel bronze, silver or steel.
  • the slip rings are connected by insulating fastenings to the shaft of the post 514 to form slipring bodies. Electrically conductive brushes are disposed stationarily along the circumference of the slip rings and are held in contact with the surface of the slip rings by spring force.
  • the sliding contacts (brushes) generally are formed of carbon materials, possibly in combination with metals, for example metal graphite.
  • Terminal 612 acts as a terminal for the wires. In an embodiment, terminal 612 does not have a rotating feature.
  • Wire 602c is substantially rigid and ring 610 is made of a low-friction material that when the transducer 111 rotates about the post 514, it pulls with it the ring 610.
  • the rotation of the transducer 111 can be modified to go either clockwise or counter-clockwise about the post 514.
  • the ring 610 rotates using carbon brush rings which makes electrical connections using wire 602a or wire 602b.
  • the wires 602a, 602b are embedded in the post 514.
  • the shaft of the post 514 can have two components to facilitate assembly. One component can be non-conductive towards the connection end and the other component can be conduct!

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

L'invention concerne un cathéter comprenant une tige de cathéter et un transducteur ultrasonore auto-rotatif positionné le long d'un axe longitudinal sur une région distale de la tige de cathéter, le transducteur ultrasonore auto-rotatif ayant une forme dans laquelle le transducteur ultrasonore auto-rotatif est conçu pour tourner automatiquement autour de l'axe longitudinal lorsqu'une force de rayonnement acoustique génère une quantité de mouvement nette à partir de forces réactives provenant d'un environnement ambiant qui a un couple net non nul autour d'un axe de rotation du transducteur ultrasonore auto-rotatif.
EP23805671.7A 2022-11-11 2023-11-07 Cylindre rotatif Pending EP4615571A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263383366P 2022-11-11 2022-11-11
PCT/IB2023/061241 WO2024100558A1 (fr) 2022-11-11 2023-11-07 Cylindre rotatif

Publications (1)

Publication Number Publication Date
EP4615571A1 true EP4615571A1 (fr) 2025-09-17

Family

ID=88793003

Family Applications (1)

Application Number Title Priority Date Filing Date
EP23805671.7A Pending EP4615571A1 (fr) 2022-11-11 2023-11-07 Cylindre rotatif

Country Status (2)

Country Link
EP (1) EP4615571A1 (fr)
WO (1) WO2024100558A1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5271402A (en) * 1992-06-02 1993-12-21 Hewlett-Packard Company Turbine drive mechanism for steering ultrasound signals
US5509418A (en) * 1995-01-17 1996-04-23 Hewlett-Packard Co. Ultrasound diagnostic probe having acoustically driven turbin
US9833217B2 (en) * 2008-12-31 2017-12-05 St. Jude Medical, Atrial Fibrillation Division, Inc. Methods and apparatus for utilizing impeller-based rotationally-scanning catheters
US9192790B2 (en) * 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
JP2024507395A (ja) * 2021-02-25 2024-02-19 ヒーリアム メディカル リミテッド 超音波組織治療装置

Also Published As

Publication number Publication date
WO2024100558A1 (fr) 2024-05-16

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