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EP4580479A1 - Dispositif de détermination de la longueur d'un objet, en particulier de la longueur d'un oeil - Google Patents

Dispositif de détermination de la longueur d'un objet, en particulier de la longueur d'un oeil

Info

Publication number
EP4580479A1
EP4580479A1 EP23736075.5A EP23736075A EP4580479A1 EP 4580479 A1 EP4580479 A1 EP 4580479A1 EP 23736075 A EP23736075 A EP 23736075A EP 4580479 A1 EP4580479 A1 EP 4580479A1
Authority
EP
European Patent Office
Prior art keywords
eye
oct
length
dispersion
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP23736075.5A
Other languages
German (de)
English (en)
Inventor
Frank Karlheinz MÜLLER
Tilman Philipp OTTO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heidelberg Engineering GmbH
Original Assignee
Heidelberg Engineering GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heidelberg Engineering GmbH filed Critical Heidelberg Engineering GmbH
Publication of EP4580479A1 publication Critical patent/EP4580479A1/fr
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/0209—Low-coherence interferometers
    • G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/1005—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring distances inside the eye, e.g. thickness of the cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02083—Interferometers characterised by particular signal processing and presentation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
    • G01B9/02002—Interferometers characterised by controlling or generating intrinsic radiation properties using two or more frequencies
    • G01B9/02004—Interferometers characterised by controlling or generating intrinsic radiation properties using two or more frequencies using frequency scans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02041—Interferometers characterised by particular imaging or detection techniques
    • G01B9/02044—Imaging in the frequency domain, e.g. by using a spectrometer

Definitions

  • optical coherence tomography in English “Optical Coherence Tomography”, usually abbreviated to OCT) refers to an imaging procedure. With this process, two- and three-dimensional images can be obtained from light-scattering structures.
  • the light reflected from the sample or object interferes with the reference beam.
  • the sample can be examined with depth resolution, i.e. at the depth of the optical axis of the first partial beam, using so-called A-scans.
  • depth resolution i.e. at the depth of the optical axis of the first partial beam
  • A-scans so-called A-scans.
  • TD-OCT Time Domain OCT
  • FD-OCT Frequency Domain OCT
  • a scanned cSLO image or an OCT slice has different sizes without correction.
  • biometric devices that simultaneously record a rough image of the retina, for which a scaling can be determined using the length determined by the devices.
  • the present invention solves the aforementioned problem through the features of claim 1. According to the invention, it was first recognized that light which penetrates into a dispersive object to be examined experiences dispersion, namely that the object influences the speed of propagation of the light depending on its frequency. It has also been recognized that an evaluation unit must be provided in such a device, which analyzes interferometric data obtained from an OCT signal or interference spectrum, determines dispersion-related data of the interferometric data and uses the dispersion-related data to determine the length of the object. According to the invention, the axial length of the object, in particular the human eye, is measured by detecting the dispersion.
  • dispersion is normally a disturbing factor that leads to poorer image quality, which is why dispersive effects in OCT devices are compensated for by hardware and/or software.
  • the effect of dispersion is used to measure lengths.
  • corneal curvature and refraction are used to estimate the axial length of the eye and thus determine scaling.
  • the determination of the axial length of the eye will be incorrect if eye parameters that are not taken into account, for example corneal curvature of the second surface, the anterior chamber depth and lens parameters, deviate from the model eye used. This is particularly the case when a patient's refractive error has been corrected through the use of intraocular lenses (IOLs) or through refractive surgery.
  • IOLs intraocular lenses
  • the direct measurement of the axial length of the eye is therefore a much more robust parameter for a scaling determination.
  • classification methods can achieve higher test power.
  • Methods in which no dense volume is recorded, but which use scan patterns or scan patterns with fixed scaling, also benefit from a better match between the recording location of the recorded OCT cross-sectional images and the target positions. For example, for circular scans with a selected absolute radius, especially in the millimeter range, the actual radius in the eye will vary less.
  • the evaluation unit could determine the length of the object by fitting it to a model or using a model that represents the influence of dispersion on light depending on the distance that the light has traveled in a dispersive medium.
  • a refractive index depends on the frequency of the light incident on that media. This effect of dispersion is used to determine the length of the object.
  • the evaluation unit could access a predefined model that theoretically describes the dispersion, namely the influence of a medium on the speed of propagation of light in this medium.
  • models could be stored in a storage medium of the device.
  • the most suitable model can be accessed in order to approximately theoretically describe the dispersion behavior of the object being examined and to draw conclusions about the length of the object based on experimental values.
  • the model could describe the dispersion behavior of one or more media of the human eye. This makes it possible to reliably measure the length of an eye.
  • the naturally existing dispersion of ocular media can be used to determine the length of the eye when performing FD-OCT, especially without additional hardware.
  • the interferometric data could include A-scans or OCT images generated from partial spectra of an interference spectrum.
  • A-scans are generated at the depth of a beam direction so that dispersion influences along an optical path length can be concluded from them.
  • the evaluation unit could determine an axial distance between two A-scans or two OCT images along a beam direction to determine the dispersion-related data.
  • the evaluation unit could create an adaptation curve or fit curve through values obtained from the dispersion-related data in order to determine the length of the object being examined. In this way, a length measure can be deduced from experimentally determined data by comparing theoretical values with experimental ones.
  • the device used here could be used as an FD-OCT, namely as a device for carrying out a frequency domain optical coherence tomography (FD-OCT), in particular for carrying out a spectral domain optical coherence tomography (SD-OCT) or for carrying out a swept-source optical coherence tomography (SS-OCT) is suitable.
  • FD-OCT frequency domain optical coherence tomography
  • SD-OCT spectral domain optical coherence tomography
  • SS-OCT swept-source optical coherence tomography
  • 1 shows a schematic representation of an image of the posterior section of the eye using OCT or cSLO, in which the field of view angle is known as a device parameter, but the size of the imaged area at the fundus d is not directly accessible because the optics and size of the eye are not known
  • 2 shows a schematic representation of different eyes, each of which has different lengths
  • A-scans 6a, 6b or OCT images 6'a, 6'b are used together, in particular strips of adjacent A-scans 6a, 6b or OCT images 6'a, 6'b, around the relative axial offset 8 of images 6'a, 6'b from the partial spectra.
  • the procedure creates an OCT signal of the retina recorded and the length 3 of eye 2 is determined.
  • An OCT signal is recorded specifically at the back of the eye and the length 3 of eye 2 is determined.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Signal Processing (AREA)
  • Eye Examination Apparatus (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

L'invention concerne un dispositif (1) pour effectuer une tomographie par cohérence optique (OCT), comprenant : un interféromètre (1a) pour guider un faisceau lumineux (4) dans un objet dispersif à examiner, lequel objet influence le taux de propagation de la lumière (4a, 4b, 4c) en fonction de la fréquence de celui-ci ; et une unité d'évaluation (5) pour détecter une longueur (3) de l'objet. Par rapport au problème de détection de la longueur d'un objet transilluminé de la manière la plus fiable possible au moyen d'un dispositif pour effectuer une tomographie par cohérence optique, le dispositif est caractérisé en ce que l'unité d'évaluation (5) analyse des données interférométriques obtenues à partir d'un signal OCT ou d'un spectre d'interférence et détermine des données relatives à la dispersion des données interférométriques et détermine la longueur (3) à l'aide des données relatives à la dispersion.
EP23736075.5A 2022-09-01 2023-06-28 Dispositif de détermination de la longueur d'un objet, en particulier de la longueur d'un oeil Pending EP4580479A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102022122164.4A DE102022122164A1 (de) 2022-09-01 2022-09-01 Vorrichtung zur Ermittlung der Länge eines Objekts, insbesondere der Länge eines Auges
PCT/EP2023/067634 WO2024046620A1 (fr) 2022-09-01 2023-06-28 Dispositif de détermination de la longueur d'un objet, en particulier de la longueur d'un œil

Publications (1)

Publication Number Publication Date
EP4580479A1 true EP4580479A1 (fr) 2025-07-09

Family

ID=87067105

Family Applications (1)

Application Number Title Priority Date Filing Date
EP23736075.5A Pending EP4580479A1 (fr) 2022-09-01 2023-06-28 Dispositif de détermination de la longueur d'un objet, en particulier de la longueur d'un oeil

Country Status (5)

Country Link
EP (1) EP4580479A1 (fr)
JP (1) JP2025529222A (fr)
CN (1) CN119816239A (fr)
DE (1) DE102022122164A1 (fr)
WO (1) WO2024046620A1 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005019471A1 (de) * 2005-04-27 2006-11-09 Carl Zeiss Meditec Ag Verfahren und Anordnung zur nichtinvasiven Blutzuckermessung
EP1806092A1 (fr) * 2006-01-10 2007-07-11 Kabushiki Kaisha TOPCON Dispositif d'observation de fond d'oeil
US7878651B2 (en) * 2007-12-26 2011-02-01 Carl Zeiss Meditec, Inc. Refractive prescription using optical coherence tomography
DE102011116760A1 (de) * 2011-10-20 2013-04-25 Carl Zeiss Meditec Ag Ophthalmologisches Lasersystem und Verfahren zur laserchirurgischen Behandlung der Cornea
US10743758B2 (en) * 2015-03-25 2020-08-18 Amo Development, Llc Multiple depth optical coherence tomography system and method and laser eye surgery system incorporating the same
JP7601643B2 (ja) * 2021-01-19 2024-12-17 株式会社トプコン 眼科装置、眼科装置の制御方法、及びプログラム

Also Published As

Publication number Publication date
DE102022122164A1 (de) 2024-03-07
CN119816239A (zh) 2025-04-11
JP2025529222A (ja) 2025-09-04
WO2024046620A1 (fr) 2024-03-07

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