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EP4333979A4 - Procédé de titrage de doses d'agents psychédéliques - Google Patents

Procédé de titrage de doses d'agents psychédéliques

Info

Publication number
EP4333979A4
EP4333979A4 EP22799340.9A EP22799340A EP4333979A4 EP 4333979 A4 EP4333979 A4 EP 4333979A4 EP 22799340 A EP22799340 A EP 22799340A EP 4333979 A4 EP4333979 A4 EP 4333979A4
Authority
EP
European Patent Office
Prior art keywords
psychedelics
titration
dose
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22799340.9A
Other languages
German (de)
English (en)
Other versions
EP4333979A1 (fr
Inventor
Robert Barrow
Daniel R. Karlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mind Medicine Inc
Original Assignee
Mind Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mind Medicine Inc filed Critical Mind Medicine Inc
Publication of EP4333979A1 publication Critical patent/EP4333979A1/fr
Publication of EP4333979A4 publication Critical patent/EP4333979A4/fr
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/48Ergoline derivatives, e.g. lysergic acid, ergotamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Dental Preparations (AREA)
  • Measurement Of Radiation (AREA)
EP22799340.9A 2021-05-03 2022-05-01 Procédé de titrage de doses d'agents psychédéliques Pending EP4333979A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163183579P 2021-05-03 2021-05-03
PCT/US2022/027179 WO2022235529A1 (fr) 2021-05-03 2022-05-01 Procédé de titrage de doses d'agents psychédéliques

Publications (2)

Publication Number Publication Date
EP4333979A1 EP4333979A1 (fr) 2024-03-13
EP4333979A4 true EP4333979A4 (fr) 2025-01-15

Family

ID=83932279

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22799340.9A Pending EP4333979A4 (fr) 2021-05-03 2022-05-01 Procédé de titrage de doses d'agents psychédéliques

Country Status (7)

Country Link
EP (1) EP4333979A4 (fr)
JP (1) JP2024517194A (fr)
AU (2) AU2022268891A1 (fr)
CA (1) CA3216939A1 (fr)
IL (1) IL308068A (fr)
TW (1) TW202245767A (fr)
WO (1) WO2022235529A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3182156A1 (fr) 2020-05-08 2021-11-11 Psilera Inc. Nouvelles compositions de matiere et compositions pharmaceutiques
US12378194B2 (en) 2021-05-25 2025-08-05 Atai Therapeutics, Inc. N, n-dimethyltryptamine salts and crystalline salt forms
WO2022261383A1 (fr) 2021-06-09 2022-12-15 ATAI Life Sciences AG Nouveaux promédicaments et conjugués de diméthyltryptamine
JP2024531437A (ja) 2021-08-20 2024-08-29 ファーマラ バイオテック インコーポレイテッド (r)-3,4-メチレンジオキシメタンフェタミン及び(s)-3,4-メチレンジオキシメタンフェタミン又は(r)n-メチル-1,3-ベンゾジオキソリルブタンアミン及び(s)n-メチル-1,3-ベンゾジオキソリルブタンアミンの非ラセミ混合物を含む組成物、並びにその使用
CA3238440A1 (fr) 2021-12-30 2023-07-06 Atai Therapeutics, Inc. Analogues de dimethyltryptamine utilises en tant que medicaments d'administration d'oxyde nitrique
EP4486448A1 (fr) 2022-03-04 2025-01-08 Reset Pharmaceuticals, Inc. Co-cristaux ou sels comprenant de la psilocine

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170157343A1 (en) * 2014-06-30 2017-06-08 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
WO2020157569A1 (fr) * 2019-01-30 2020-08-06 Diamond Therapeutics Inc. Compositions et méthodes comprenant un agoniste de récepteur 5ht destinées au traitement de troubles psychologiques, cognitifs, comportementaux et/ou d'humeur
WO2020169850A1 (fr) * 2019-02-22 2020-08-27 Gh Research Limited 5-méthoxy-n,n-diméthyltryptamine (5-méo-dmt) pour la traitement de la dépression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA50786A (fr) * 2017-10-26 2022-04-27 Blumentech S L Produit d'association pour le traitement de troubles neurologiques et/ou psychiatriques
WO2021003467A1 (fr) * 2019-07-04 2021-01-07 Sw Holdings, Inc. Compositions de dosage et procédés d'utilisation de composés psychédéliques

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170157343A1 (en) * 2014-06-30 2017-06-08 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
WO2020157569A1 (fr) * 2019-01-30 2020-08-06 Diamond Therapeutics Inc. Compositions et méthodes comprenant un agoniste de récepteur 5ht destinées au traitement de troubles psychologiques, cognitifs, comportementaux et/ou d'humeur
WO2020169850A1 (fr) * 2019-02-22 2020-08-27 Gh Research Limited 5-méthoxy-n,n-diméthyltryptamine (5-méo-dmt) pour la traitement de la dépression

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "How to Microdose: A Step by Step Guide - Microdosing information, research, community, coaching and more.", 30 April 2021 (2021-04-30), pages 1 - 9, XP093230199, Retrieved from the Internet <URL:https://web.archive.org/web/20210430131601/https://microdosinginstitute.com/how-to/how-to-microdose/> *
KUYPERS KIM P.C.: "The therapeutic potential of microdosing psychedelics in depression", vol. 10, 27 August 2020 (2020-08-27), XP093229382, ISSN: 2045-1253, Retrieved from the Internet <URL:https://journals.sagepub.com/doi/pdf/10.1177/2045125320950567> DOI: 10.1177/2045125320950567 *
See also references of WO2022235529A1 *

Also Published As

Publication number Publication date
AU2022268891A1 (en) 2023-11-09
EP4333979A1 (fr) 2024-03-13
TW202245767A (zh) 2022-12-01
JP2024517194A (ja) 2024-04-19
CA3216939A1 (fr) 2022-11-10
AU2025217270A1 (en) 2025-08-28
WO2022235529A1 (fr) 2022-11-10
IL308068A (en) 2023-12-01

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