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EP4355769A4 - Dimeric collagen hybridizing peptides and methods of use thereof - Google Patents

Dimeric collagen hybridizing peptides and methods of use thereof

Info

Publication number
EP4355769A4
EP4355769A4 EP22825737.4A EP22825737A EP4355769A4 EP 4355769 A4 EP4355769 A4 EP 4355769A4 EP 22825737 A EP22825737 A EP 22825737A EP 4355769 A4 EP4355769 A4 EP 4355769A4
Authority
EP
European Patent Office
Prior art keywords
methods
collagen hybridizing
hybridizing peptides
dimeric collagen
dimeric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP22825737.4A
Other languages
German (de)
French (fr)
Other versions
EP4355769A1 (en
Inventor
Julian L. KESSLER
Michael S. YU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah Research Foundation Inc
Original Assignee
University of Utah Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Utah Research Foundation Inc filed Critical University of Utah Research Foundation Inc
Publication of EP4355769A1 publication Critical patent/EP4355769A1/en
Publication of EP4355769A4 publication Critical patent/EP4355769A4/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804Affinity chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
EP22825737.4A 2021-06-15 2022-06-15 Dimeric collagen hybridizing peptides and methods of use thereof Pending EP4355769A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17/348,694 US20220050116A1 (en) 2020-06-15 2021-06-15 Dimeric collagen hybridizing peptides and methods of use thereof
PCT/US2022/033594 WO2022266200A1 (en) 2021-06-15 2022-06-15 Dimeric collagen hybridizing peptides and methods of use thereof

Publications (2)

Publication Number Publication Date
EP4355769A1 EP4355769A1 (en) 2024-04-24
EP4355769A4 true EP4355769A4 (en) 2025-04-30

Family

ID=94925111

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22825737.4A Pending EP4355769A4 (en) 2021-06-15 2022-06-15 Dimeric collagen hybridizing peptides and methods of use thereof

Country Status (3)

Country Link
US (1) US20220050116A1 (en)
EP (1) EP4355769A4 (en)
WO (1) WO2022266200A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115925988B (en) * 2022-09-14 2023-08-22 中山大学附属第五医院 A denatured collagen targeting antimicrobial peptide and its preparation method and application
KR20250155043A (en) * 2023-03-02 2025-10-29 3헬릭스, 인코포레이티드 Anti-inflammatory bioactive collagen hybrid peptides and methods of using the same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180000960A1 (en) * 2015-01-30 2018-01-04 University Of Utah Research Foundation Dimeric collagen hybridizing peptides and methods of using
WO2019044894A1 (en) * 2017-08-31 2019-03-07 学校法人早稲田大学 Cyclic peptide having collagen binding activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013078091A1 (en) * 2011-11-22 2013-05-30 The Johns Hopkins University Collagen mimetic peptides for targeting collagen strands for in vitro and in vivo imaging and therapeutic use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180000960A1 (en) * 2015-01-30 2018-01-04 University Of Utah Research Foundation Dimeric collagen hybridizing peptides and methods of using
WO2019044894A1 (en) * 2017-08-31 2019-03-07 学校法人早稲田大学 Cyclic peptide having collagen binding activity

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KESSLER JULIAN L ET AL: "Supporting Information: Enrichment of Collagen Fragments Using Dimeric Collagen Hybridizing Peptide for Urinary Collagenomics", JOURNAL OF PROTEOME RESEARCH, vol. 19, no. 8, 5 June 2020 (2020-06-05), pages S1 - S18, XP093259402 *
KESSLER JULIAN L. ET AL: "Enrichment of Collagen Fragments Using Dimeric Collagen Hybridizing Peptide for Urinary Collagenomics", JOURNAL OF PROTEOME RESEARCH, vol. 19, no. 8, 5 June 2020 (2020-06-05), pages 2926 - 2932, XP093259396, ISSN: 1535-3893, DOI: 10.1021/acs.jproteome.0c00055 *
See also references of WO2022266200A1 *

Also Published As

Publication number Publication date
US20220050116A1 (en) 2022-02-17
WO2022266200A1 (en) 2022-12-22
EP4355769A1 (en) 2024-04-24

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Legal Events

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STAA Information on the status of an ep patent application or granted ep patent

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20240112

AK Designated contracting states

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Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20250401

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 19/10 20060101ALI20250326BHEP

Ipc: A61K 47/65 20170101ALI20250326BHEP

Ipc: B01D 15/38 20060101ALI20250326BHEP

Ipc: A61K 47/64 20170101ALI20250326BHEP

Ipc: G01N 33/68 20060101ALI20250326BHEP

Ipc: C07K 14/78 20060101AFI20250326BHEP