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EP4225501A4 - SYSTEM FOR DETERMINING A BIOLOGICAL STATE AND CARTRIDGE THEREFOR - Google Patents

SYSTEM FOR DETERMINING A BIOLOGICAL STATE AND CARTRIDGE THEREFOR Download PDF

Info

Publication number
EP4225501A4
EP4225501A4 EP21877143.4A EP21877143A EP4225501A4 EP 4225501 A4 EP4225501 A4 EP 4225501A4 EP 21877143 A EP21877143 A EP 21877143A EP 4225501 A4 EP4225501 A4 EP 4225501A4
Authority
EP
European Patent Office
Prior art keywords
determining
biological state
cartridge therefor
therefor
cartridge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21877143.4A
Other languages
German (de)
French (fr)
Other versions
EP4225501A1 (en
Inventor
Ilan SEMMEL
Warren Edward FARNAM III
Eric STIMPSON
Zion Botesazan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Accellix Ltd
Original Assignee
Accellix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Accellix Ltd filed Critical Accellix Ltd
Publication of EP4225501A1 publication Critical patent/EP4225501A1/en
Publication of EP4225501A4 publication Critical patent/EP4225501A4/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484Optical investigation techniques, e.g. flow cytometry microstructural devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04Exchange or ejection of cartridges, containers or reservoirs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16Reagents, handling or storing thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883Serpentine channels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
EP21877143.4A 2020-10-07 2021-10-07 SYSTEM FOR DETERMINING A BIOLOGICAL STATE AND CARTRIDGE THEREFOR Pending EP4225501A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063088470P 2020-10-07 2020-10-07
PCT/IL2021/051208 WO2022074657A1 (en) 2020-10-07 2021-10-07 System for determining a biological condition and cartridge therefor

Publications (2)

Publication Number Publication Date
EP4225501A1 EP4225501A1 (en) 2023-08-16
EP4225501A4 true EP4225501A4 (en) 2024-10-30

Family

ID=81125736

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21877143.4A Pending EP4225501A4 (en) 2020-10-07 2021-10-07 SYSTEM FOR DETERMINING A BIOLOGICAL STATE AND CARTRIDGE THEREFOR

Country Status (6)

Country Link
EP (1) EP4225501A4 (en)
JP (1) JP2023545415A (en)
KR (1) KR20230079276A (en)
CN (1) CN116438455A (en)
AU (2) AU2021356770B2 (en)
WO (1) WO2022074657A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118048223B (en) * 2024-03-29 2025-01-17 中国科学院过程工程研究所 Nucleic acid extraction device
CN118028094A (en) * 2024-03-29 2024-05-14 中国科学院过程工程研究所 Nucleic acid detection system

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120329142A1 (en) * 2006-03-15 2012-12-27 Micronics, Inc. Integrated nucleic acid assays
US20150158026A1 (en) * 2006-06-23 2015-06-11 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US20170113221A1 (en) * 2014-06-11 2017-04-27 Micronics, Inc. Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids
US20180015474A1 (en) * 2015-02-02 2018-01-18 Atlas Genetics Limited Instrument for performing a diagnostic test on a fluidic cartridge

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9052309B2 (en) * 2010-12-03 2015-06-09 Abbott Point Of Care Inc. Ratiometric immunoassay method and blood testing device
US10006867B2 (en) * 2012-12-03 2018-06-26 The Secretary of State of Environment, Food and Rural Affairs, acting through the Animal and Plant Health Agency. Device and apparatus
WO2014097286A1 (en) * 2012-12-17 2014-06-26 Leukodx, Ltd. Systems and methods for determining a chemical state
JP2016130652A (en) * 2015-01-13 2016-07-21 株式会社フジクラ Inspection device, inspection method and inspection apparatus
WO2016172724A1 (en) * 2015-04-24 2016-10-27 Mesa Biotech, Inc. Fluidic test cassette
KR101765474B1 (en) * 2015-11-26 2017-08-07 경희대학교 산학협력단 Diagnosis Kit for Virus
CN117443474B (en) * 2018-12-13 2025-02-14 迪亚莱博(张家港)生物科技有限公司 Microfluidic chip and detection method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120329142A1 (en) * 2006-03-15 2012-12-27 Micronics, Inc. Integrated nucleic acid assays
US20150158026A1 (en) * 2006-06-23 2015-06-11 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US20170113221A1 (en) * 2014-06-11 2017-04-27 Micronics, Inc. Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids
US20180015474A1 (en) * 2015-02-02 2018-01-18 Atlas Genetics Limited Instrument for performing a diagnostic test on a fluidic cartridge

Also Published As

Publication number Publication date
JP2023545415A (en) 2023-10-30
WO2022074657A1 (en) 2022-04-14
AU2021356770B2 (en) 2025-05-08
KR20230079276A (en) 2023-06-05
EP4225501A1 (en) 2023-08-16
CN116438455A (en) 2023-07-14
AU2025210862A1 (en) 2025-08-21
AU2021356770A1 (en) 2023-06-01

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RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 15/10 20060101ALI20240926BHEP

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Ipc: G01N 15/14 20060101ALI20240926BHEP

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