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EP4258874A4 - ANTIVIRAL OLIVE EXTRACT COMPOSITIONS AND METHODS - Google Patents

ANTIVIRAL OLIVE EXTRACT COMPOSITIONS AND METHODS Download PDF

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Publication number
EP4258874A4
EP4258874A4 EP21904253.8A EP21904253A EP4258874A4 EP 4258874 A4 EP4258874 A4 EP 4258874A4 EP 21904253 A EP21904253 A EP 21904253A EP 4258874 A4 EP4258874 A4 EP 4258874A4
Authority
EP
European Patent Office
Prior art keywords
antiviral
methods
olive extract
extract compositions
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21904253.8A
Other languages
German (de)
French (fr)
Other versions
EP4258874A1 (en
Inventor
Roberto Crea
Yohei Takeda
Haruko Ogawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Obihiro University of Agriculture and Veterinary Medicine NUC
Oliphenol LLC
Original Assignee
Obihiro University of Agriculture and Veterinary Medicine NUC
Oliphenol LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/326,146 external-priority patent/US11951143B2/en
Application filed by Obihiro University of Agriculture and Veterinary Medicine NUC, Oliphenol LLC filed Critical Obihiro University of Agriculture and Veterinary Medicine NUC
Publication of EP4258874A1 publication Critical patent/EP4258874A1/en
Publication of EP4258874A4 publication Critical patent/EP4258874A4/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/22Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01PBIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P1/00Disinfectants; Antimicrobial compounds or mixtures thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • A61K31/775Phenolic resins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Botany (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Medical Informatics (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pest Control & Pesticides (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP21904253.8A 2020-12-08 2021-12-07 ANTIVIRAL OLIVE EXTRACT COMPOSITIONS AND METHODS Pending EP4258874A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063122893P 2020-12-08 2020-12-08
US17/326,146 US11951143B2 (en) 2017-01-04 2021-05-20 Olive oil use
PCT/US2021/062213 WO2022125552A1 (en) 2020-12-08 2021-12-07 Antiviral olive extract compositions and methods

Publications (2)

Publication Number Publication Date
EP4258874A1 EP4258874A1 (en) 2023-10-18
EP4258874A4 true EP4258874A4 (en) 2024-12-18

Family

ID=81973957

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21904253.8A Pending EP4258874A4 (en) 2020-12-08 2021-12-07 ANTIVIRAL OLIVE EXTRACT COMPOSITIONS AND METHODS

Country Status (3)

Country Link
EP (1) EP4258874A4 (en)
CA (1) CA3201770A1 (en)
WO (1) WO2022125552A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117844A (en) * 1994-11-07 2000-09-12 F&S Group, Inc. Method and composition for antiviral therapy
US20020110600A1 (en) * 2001-02-15 2002-08-15 John Voorhees Composition for treating symptoms of influenza
WO2008143137A1 (en) * 2007-05-24 2008-11-27 National University Corporation, Obihiro University Of Agriculture And Veterinary Medicine Antiviral agent
US20200138843A1 (en) * 2018-11-06 2020-05-07 ATLAS OLIVE OILS Sarl. Compositions for treating pain and inflammation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416808B1 (en) * 2000-09-01 2002-07-09 Creagri, Inc. Method of obtaining a hydroxytyrosol-rich composition from vegetation water
US20090061031A1 (en) * 2006-07-07 2009-03-05 Sylvia Lee-Huang Compositions and methods for treating obesity, obesity related disorders and for inhibiting the infectivity of human immunodeficiency virus
EP2635120A1 (en) * 2010-08-06 2013-09-11 Phyto Innovative Products Ltd Compositions comprising oleuropeins and flavanoids and their use
US8846114B1 (en) * 2013-09-05 2014-09-30 Oleavicin, LLC Composition for the treatment of herpes and cold sores

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117844A (en) * 1994-11-07 2000-09-12 F&S Group, Inc. Method and composition for antiviral therapy
US20020110600A1 (en) * 2001-02-15 2002-08-15 John Voorhees Composition for treating symptoms of influenza
WO2008143137A1 (en) * 2007-05-24 2008-11-27 National University Corporation, Obihiro University Of Agriculture And Veterinary Medicine Antiviral agent
US20200138843A1 (en) * 2018-11-06 2020-05-07 ATLAS OLIVE OILS Sarl. Compositions for treating pain and inflammation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
See also references of WO2022125552A1 *
SUN ZIQI ET AL: "Future antiviral surfaces: Lessons from COVID-19 pandemic", SUSTAINABLE MATERIALS AND TECHNOLOGIES, vol. 25, 1 September 2020 (2020-09-01), pages e00203, XP055795359, ISSN: 2214-9937, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376362/pdf/main.pdf> DOI: 10.1016/j.susmat.2020.e00203 *
YAMADA K ET AL: "Mechanism of the antiviral effect of hydroxytyrosol on influenza virus appears to involve morphological change of the virus", ANTIVIRAL RESEARCH, ELSEVIER BV, NL, vol. 83, no. 1, 1 July 2009 (2009-07-01), pages 35 - 44, XP026149756, ISSN: 0166-3542, [retrieved on 20090324], DOI: 10.1016/J.ANTIVIRAL.2009.03.002 *

Also Published As

Publication number Publication date
CA3201770A1 (en) 2022-06-16
WO2022125552A1 (en) 2022-06-16
EP4258874A1 (en) 2023-10-18

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A4 Supplementary search report drawn up and despatched

Effective date: 20241114

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 47/14 20170101ALI20241108BHEP

Ipc: A61K 9/08 20060101ALI20241108BHEP

Ipc: A61K 31/192 20060101ALI20241108BHEP

Ipc: A61P 31/12 20060101ALI20241108BHEP

Ipc: A61K 31/351 20060101ALI20241108BHEP

Ipc: A61K 31/05 20060101ALI20241108BHEP

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Ipc: A01N 35/02 20060101ALI20241108BHEP

Ipc: A01N 31/08 20060101ALI20241108BHEP

Ipc: A01N 27/00 20060101AFI20241108BHEP