EP4140992C0 - PROCESS FOR THE PRODUCTION OF S-NICOTINE - Google Patents

PROCESS FOR THE PRODUCTION OF S-NICOTINE

Info

Publication number: EP4140992C0
Authority: EP; European Patent Office
Prior art keywords: nicotine; production
Prior art date: 2021-07-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

EP21810886.8A

Other languages

German (de)

French (fr)

Other versions

EP4140992A4 (en

EP4140992A1 (en

EP4140992B1 (en

Inventor

Jun Zou

Yang Zou

Meisen Liu

Weixian Luo

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Shenzhen Zinwi Biotech Co Ltd

Original Assignee

Shenzhen Zinwi Biotech Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2021-07-10

Filing date

2021-08-16

Publication date

2024-10-16

2021-08-16 Application filed by Shenzhen Zinwi Biotech Co Ltd filed Critical Shenzhen Zinwi Biotech Co Ltd

2023-03-01 Publication of EP4140992A1 publication Critical patent/EP4140992A1/en

2023-12-06 Publication of EP4140992A4 publication Critical patent/EP4140992A4/en

2024-10-16 Application granted granted Critical

2024-10-16 Publication of EP4140992C0 publication Critical patent/EP4140992C0/en

2024-10-16 Publication of EP4140992B1 publication Critical patent/EP4140992B1/en

Status Active legal-status Critical Current

2041-08-16 Anticipated expiration legal-status Critical

Classifications

- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/12—Chemical features of tobacco products or tobacco substitutes of reconstituted tobacco
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances

Landscapes

Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

EP21810886.8A 2021-07-10 2021-08-16 Method for preparing s-nicotine Active EP4140992B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CN202110781163.8A CN113475739B (en)	2021-07-10	2021-07-10	Preparation method of S-nicotine
PCT/CN2021/112793 WO2023284057A1 (en)	2021-07-10	2021-08-16	Method for preparing s-nicotine

Publications (4)

Publication Number	Publication Date
EP4140992A1 EP4140992A1 (en)	2023-03-01
EP4140992A4 EP4140992A4 (en)	2023-12-06
EP4140992C0 true EP4140992C0 (en)	2024-10-16
EP4140992B1 EP4140992B1 (en)	2024-10-16

Family

ID=77938477

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP21810886.8A Active EP4140992B1 (en)	2021-07-10	2021-08-16	Method for preparing s-nicotine

Country Status (3)

Country	Link
EP (1)	EP4140992B1 (en)
CN (1)	CN113475739B (en)
WO (1)	WO2023284057A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN114276204B (en) *	2021-12-24	2024-02-27	大庆雾泰化工科技有限公司	Preparation method of (S) - (-) -nicotine
CN114437031B (en) *	2022-02-16	2023-06-27	深圳市真味生物科技有限公司	Synthesis method of 6-methyl nicotine

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5045550A (en) *	1990-09-20	1991-09-03	Warner-Lambert Co.	Substituted tetrahydropyridines as central nervous system agents
US5187280A (en) *	1990-09-20	1993-02-16	Warner-Lambert Company	Substituted tetrahydropyridines and their use as central nervous system agents
US5648541A (en) *	1995-09-28	1997-07-15	Nps Pharmaceuticals, Inc.	Chiral reductions of imines leading to the syntheses of optically active amines
JPH11312351A (en)	1998-04-28	1999-11-09	Sony Corp	Disc loading device
CN1106892C (en) *	2000-10-16	2003-04-30	云南万芳生物技术有限公司	Process for extracting pure tobacco oil, melanoid and nicotine and preparing composite fertilizer
US20030224435A1 (en) *	2002-05-16	2003-12-04	Scott Seiwert	Detection of abused substances and their metabolites using nucleic acid sensor molecules
US8367837B2 (en) *	2011-02-14	2013-02-05	Divi's Laboratories, Ltd.	Process for the preparation of (R,S)-nicotine
CN104341390B (en)	2014-11-04	2016-09-07	南开大学	A kind of botanical pesticide nicotine and the method for asymmetric synthesis of anabasine
US9809567B2 (en) *	2014-12-09	2017-11-07	Njoy, Llc	Synthesis and resolution of nicotine
CN107011321A (en) *	2017-03-27	2017-08-04	华健	A kind of preparation method of artificial synthesized raceme nicotine
CN107382916A (en) *	2017-08-30	2017-11-24	成都化润药业有限公司	The high purity synthetic process of 3 tetrahydrofurfuryl carbinols
PE20211237A1 (en) *	2017-12-22	2021-07-09	Siegfried Ag	PREPARATION OF RACEMIC NICOTINE BY REACTION OF ETHYL NICOTINATE WITH N-VINYLPYRROLIDONE IN THE PRESENCE OF AN ALCOHOLATE BASE AND SUBSEQUENT PROCESSING STEPS
CN110256403B (en) *	2019-07-02	2020-06-19	深圳市馨艺坊生物科技有限公司	Method for preparing artificial synthetic nicotine
CN110357853B (en) *	2019-08-05	2020-07-10	济南悟通生物科技有限公司	Synthesis method of (R, S-) nicotine
CN110627769A (en) *	2019-09-27	2019-12-31	深圳黑尔格科技有限公司	Iminium salt derivative, process for producing the same, and process for producing nicotine
CN111004212A (en) *	2019-12-24	2020-04-14	深圳雾芯科技有限公司	Method for preparing nicotine
CN111233829A (en) *	2019-12-27	2020-06-05	深圳黑尔格科技有限公司	Preparation method of nicotine with optical activity
KR102653443B1 (en) *	2020-03-25	2024-03-29	선전 필라이프 라이프 사이언스 컴퍼니., 리미티드.	Preparation method of artificially synthesized racemic nicotine salt
CN113527187B (en) *	2020-04-22	2023-12-26	凯特立斯（深圳）科技有限公司	A kind of asymmetric preparation method of nicotine
CN112409327A (en) *	2020-11-18	2021-02-26	山东金城医药化工有限公司	Preparation method of high-optical-purity nicotine
CN112409329A (en) *	2020-12-11	2021-02-26	山东金城医药化工有限公司	Process for the preparation of S-nicotine
CN112745294B (en) *	2020-12-30	2022-02-22	山东金城柯瑞化学有限公司	Synthesis method of (R, S-) nicotine

2021
- 2021-07-10 CN CN202110781163.8A patent/CN113475739B/en active Active
- 2021-08-16 EP EP21810886.8A patent/EP4140992B1/en active Active
- 2021-08-16 WO PCT/CN2021/112793 patent/WO2023284057A1/en not_active Ceased

Also Published As

Publication number	Publication date
CN113475739B (en)	2022-11-11
EP4140992A4 (en)	2023-12-06
WO2023284057A1 (en)	2023-01-19
CN113475739A (en)	2021-10-08
EP4140992A1 (en)	2023-03-01
EP4140992B1 (en)	2024-10-16

Publication	Publication Date	Title
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EP4328221A4 (en)	2025-07-30	METHOD FOR THE PRODUCTION OF L-NICOTINE
EP3808722A4 (en)	2022-03-23	PROCESS FOR THE PRODUCTION OF DIFLUORETHYLENE
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EP4140992C0 (en)	2024-10-16	PROCESS FOR THE PRODUCTION OF S-NICOTINE
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EP3988663A4 (en)	2023-08-02	PROCESS FOR THE PRODUCTION OF (R)-RETICULIN
EP4196463A4 (en)	2024-10-23	METHOD FOR THE PRODUCTION OF CLETHODIM
EP4239070A4 (en)	2025-09-10	PROCESS FOR THE PRODUCTION OF L-AMINO ACID

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