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EP3923925A4 - MIXED HYDROCHLORIC ACID COMPOSITIONS OF RACEMIC BETA-HYDROXYBUTYRATE AND METHOD OF USE - Google Patents

MIXED HYDROCHLORIC ACID COMPOSITIONS OF RACEMIC BETA-HYDROXYBUTYRATE AND METHOD OF USE Download PDF

Info

Publication number
EP3923925A4
EP3923925A4 EP20755994.9A EP20755994A EP3923925A4 EP 3923925 A4 EP3923925 A4 EP 3923925A4 EP 20755994 A EP20755994 A EP 20755994A EP 3923925 A4 EP3923925 A4 EP 3923925A4
Authority
EP
European Patent Office
Prior art keywords
hydroxybutyrate
hydrochloric acid
acid compositions
racemic beta
mixed hydrochloric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20755994.9A
Other languages
German (de)
French (fr)
Other versions
EP3923925A1 (en
Inventor
Gary MILLET
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axcess Global Sciences LLC
Original Assignee
Axcess Global Sciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/272,145 external-priority patent/US10736861B2/en
Priority claimed from US16/783,956 external-priority patent/US10973792B2/en
Application filed by Axcess Global Sciences LLC filed Critical Axcess Global Sciences LLC
Publication of EP3923925A1 publication Critical patent/EP3923925A1/en
Publication of EP3923925A4 publication Critical patent/EP3923925A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Confectionery (AREA)
  • Non-Alcoholic Beverages (AREA)
EP20755994.9A 2019-02-11 2020-02-10 MIXED HYDROCHLORIC ACID COMPOSITIONS OF RACEMIC BETA-HYDROXYBUTYRATE AND METHOD OF USE Pending EP3923925A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16/272,145 US10736861B2 (en) 2016-03-11 2019-02-11 Mixed salt compositions for producing elevated and sustained ketosis
US201962805054P 2019-02-13 2019-02-13
US16/720,211 US11020362B2 (en) 2016-03-11 2019-12-19 Beta-hydroxybutyrate mixed salt compositions and methods of use
US16/783,956 US10973792B2 (en) 2019-02-13 2020-02-06 Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use
PCT/US2020/017552 WO2020167690A1 (en) 2019-02-11 2020-02-10 Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use

Publications (2)

Publication Number Publication Date
EP3923925A1 EP3923925A1 (en) 2021-12-22
EP3923925A4 true EP3923925A4 (en) 2022-10-19

Family

ID=72044438

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20755994.9A Pending EP3923925A4 (en) 2019-02-11 2020-02-10 MIXED HYDROCHLORIC ACID COMPOSITIONS OF RACEMIC BETA-HYDROXYBUTYRATE AND METHOD OF USE

Country Status (6)

Country Link
EP (1) EP3923925A4 (en)
JP (2) JP7448555B2 (en)
CN (1) CN113747890A (en)
AU (1) AU2020221569B2 (en)
CA (1) CA3129541A1 (en)
WO (1) WO2020167690A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL268457B (en) 2019-08-04 2022-05-01 Omega 3 Galilee Ltd Oil suspension of edible solids and methods of preparation
US20220249497A1 (en) * 2021-02-05 2022-08-11 Health Via Modern Nutrition, Inc. Compositions and methods for improving relaxation, sleep, cognition, and/or physical performance
JP7757401B2 (en) * 2021-06-01 2025-10-21 大阪瓦斯株式会社 3-hydroxybutyric acid-containing oil and fat composition
CN115251375A (en) * 2022-07-11 2022-11-01 珠海麦得发生物科技股份有限公司 A kind of (R)-3-hydroxybutyric acid ketone product and preparation method thereof
CN115153005A (en) * 2022-07-27 2022-10-11 南京纽邦生物科技有限公司 Beta-hydroxybutyric acid compositions
US12059398B2 (en) 2022-08-26 2024-08-13 Health Via Modern Nutrition Inc. Compositions of 1,3-butanediol and beta-hydroxybutyric acid to provide optimal therapeutic ketosis
EP4595774A1 (en) * 2022-09-27 2025-08-06 Nanjing Nutrabuilding Bio-Tech Co., Ltd. Complex of 3-hydroxybutyric acid and sodium 3-hydroxybutyrate and preparation method therefor

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170258745A1 (en) * 2016-03-11 2017-09-14 Axcess Global Sciences, Llc Mixed salt compositions for producing elevated and sustained ketosis
US20180021274A1 (en) * 2016-07-21 2018-01-25 Savind, Inc. Compositions comprising beta-hydroxybutyric acid and salt, and methods of using the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004035417A (en) * 2002-06-28 2004-02-05 Kao Corp Blood total ketone body concentration enhancer
LT2001293T (en) * 2006-04-03 2018-11-12 Accera, Inc. Use of ketogenic compounds for treatment of age-associated memory impairment
PE20151949A1 (en) * 2013-03-19 2016-01-05 Univ South Florida COMPOSITIONS AND METHODS TO PRODUCE ELEVATED AND SUSTAINED KETOSIS
MY209347A (en) * 2016-04-19 2025-07-03 Axcess Global Sciences Llc Administration of butyrate, beta-hydroxybutyrate, and related compounds in humans
US20180021281A1 (en) * 2016-07-20 2018-01-25 Sciadonics, Inc. Lipid formulations containing bioactive fatty acids and other bioactive agents
US20180057846A1 (en) * 2016-08-30 2018-03-01 KetoneAid Inc. Partially buffered free acid and/or ketone blend for rapid onset ketosis and metabolic therapy
WO2018114309A1 (en) * 2016-12-23 2018-06-28 Katholieke Universiteit Leuven 3-hydroxybutyrate alone or in combination for use in the treatment of critical care treatment
BR112020001285A2 (en) * 2017-07-21 2020-07-28 Buck Institute For Research On Aging beta-hydroxybutyrate and butanediol s-enantiomers and methods for their use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170258745A1 (en) * 2016-03-11 2017-09-14 Axcess Global Sciences, Llc Mixed salt compositions for producing elevated and sustained ketosis
US20180021274A1 (en) * 2016-07-21 2018-01-25 Savind, Inc. Compositions comprising beta-hydroxybutyric acid and salt, and methods of using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020167690A1 *

Also Published As

Publication number Publication date
CN113747890A (en) 2021-12-03
JP2024014874A (en) 2024-02-01
AU2020221569B2 (en) 2025-06-26
WO2020167690A1 (en) 2020-08-20
JP7448555B2 (en) 2024-03-12
CA3129541A1 (en) 2020-08-20
EP3923925A1 (en) 2021-12-22
JP2022520205A (en) 2022-03-29
AU2020221569A1 (en) 2021-09-02

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