EP3962651A4 - Mikrofluidische vorrichtungen und verfahren zur herstellung davon - Google Patents
Mikrofluidische vorrichtungen und verfahren zur herstellung davon Download PDFInfo
- Publication number
- EP3962651A4 EP3962651A4 EP20799361.9A EP20799361A EP3962651A4 EP 3962651 A4 EP3962651 A4 EP 3962651A4 EP 20799361 A EP20799361 A EP 20799361A EP 3962651 A4 EP3962651 A4 EP 3962651A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- making
- methods
- same
- microfluidic devices
- microfluidic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
- F04B19/006—Micropumps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
- B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B17/00—Pumps characterised by combination with, or adaptation to, specific driving engines or motors
- F04B17/03—Pumps characterised by combination with, or adaptation to, specific driving engines or motors driven by electric motors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/021—Adjust spacings in an array of wells, pipettes or holders, format transfer between arrays of different size or geometry
- B01L2200/022—Variable spacings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0427—Electrowetting
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962840443P | 2019-04-30 | 2019-04-30 | |
| PCT/US2020/029276 WO2020223077A1 (en) | 2019-04-30 | 2020-04-22 | Microfluidic devices and methods of making the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3962651A1 EP3962651A1 (de) | 2022-03-09 |
| EP3962651A4 true EP3962651A4 (de) | 2022-11-23 |
Family
ID=73017701
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20799361.9A Withdrawn EP3962651A4 (de) | 2019-04-30 | 2020-04-22 | Mikrofluidische vorrichtungen und verfahren zur herstellung davon |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20200347840A1 (de) |
| EP (1) | EP3962651A4 (de) |
| TW (1) | TWI794603B (de) |
| WO (1) | WO2020223077A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11554375B2 (en) | 2019-06-07 | 2023-01-17 | Nuclera Nucleics Ltd. | Microfluidic devices containing reversibly pinned droplet samples and methods |
| US11927740B2 (en) | 2019-11-20 | 2024-03-12 | Nuclera Ltd | Spatially variable hydrophobic layers for digital microfluidics |
| CN114945426A (zh) | 2020-01-17 | 2022-08-26 | 核酸有限公司 | 用于数字微流体的空间可变介电层 |
| US11946901B2 (en) | 2020-01-27 | 2024-04-02 | Nuclera Ltd | Method for degassing liquid droplets by electrical actuation at higher temperatures |
| WO2021168131A1 (en) | 2020-02-18 | 2021-08-26 | Nuclear Nucleics Ltd. | Adaptive gate driving for high frequency ac driving of ewod arrays |
| CN115135413A (zh) | 2020-02-19 | 2022-09-30 | 核酸有限公司 | 用于EWoD阵列的高频AC驱动的锁存晶体管驱动 |
| WO2021222061A1 (en) | 2020-04-27 | 2021-11-04 | Nuclera Nucleics Ltd. | Segmented top plate for variable driving and short protection for digital microfluidics |
| CN114534805B (zh) * | 2022-02-09 | 2024-08-06 | 上海天马微电子有限公司 | 微流控装置及其驱动方法、制作方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2040082A1 (de) * | 2006-07-10 | 2009-03-25 | Hitachi High-Technologies Corporation | Flüssigkeitsübertragungsvorrichtung |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8187864B2 (en) * | 2008-10-01 | 2012-05-29 | The Governing Council Of The University Of Toronto | Exchangeable sheets pre-loaded with reagent depots for digital microfluidics |
| US20140216559A1 (en) * | 2013-02-07 | 2014-08-07 | Advanced Liquid Logic, Inc. | Droplet actuator with local variation in gap height to assist in droplet splitting and merging operations |
| WO2014175069A1 (ja) * | 2013-04-26 | 2014-10-30 | Jx日鉱日石エネルギー株式会社 | 疎水性ゾルゲル材料を用いた凹凸構造を有する基板 |
| US20150377831A1 (en) * | 2014-06-27 | 2015-12-31 | The Governing Council Of The University Of Toronto | Digital microfluidic devices and methods employing integrated nanostructured electrodeposited electrodes |
| US9623407B2 (en) * | 2015-03-27 | 2017-04-18 | International Business Machines Corporation | Microfluidic device with longitudinal and transverse liquid barriers for transverse flow mixing |
| AU2016344171B2 (en) * | 2015-10-27 | 2021-09-23 | Berkeley Lights, Inc. | Microfluidic electrowetting device apparatus having a covalently bound hydrophobic surface |
| CN109414663B (zh) * | 2016-06-29 | 2022-05-17 | 数字生物系统公司 | 在数字微流体装置中创建高分辨率温度谱线 |
| EP3697535B1 (de) * | 2017-10-18 | 2023-04-26 | Nuclera Nucleics Ltd | Digitale mikrofluidische vorrichtungen mit doppelsubstraten mit dünnschichttransistoren und kapazitiver messung |
-
2020
- 2020-04-22 WO PCT/US2020/029276 patent/WO2020223077A1/en not_active Ceased
- 2020-04-22 EP EP20799361.9A patent/EP3962651A4/de not_active Withdrawn
- 2020-04-22 US US16/855,381 patent/US20200347840A1/en not_active Abandoned
- 2020-04-28 TW TW109114161A patent/TWI794603B/zh active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2040082A1 (de) * | 2006-07-10 | 2009-03-25 | Hitachi High-Technologies Corporation | Flüssigkeitsübertragungsvorrichtung |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020223077A1 (en) | 2020-11-05 |
| TW202103785A (zh) | 2021-02-01 |
| TWI794603B (zh) | 2023-03-01 |
| EP3962651A1 (de) | 2022-03-09 |
| US20200347840A1 (en) | 2020-11-05 |
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| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
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| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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| STAA | Information on the status of an ep patent application or granted ep patent |
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| 17P | Request for examination filed |
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| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| REG | Reference to a national code |
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| A4 | Supplementary search report drawn up and despatched |
Effective date: 20221021 |
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| RIC1 | Information provided on ipc code assigned before grant |
Ipc: F04B 17/03 20060101ALI20221017BHEP Ipc: F04B 19/00 20060101AFI20221017BHEP |
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| RAP3 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: NUCLERA NUCLEICS LTD |
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| STAA | Information on the status of an ep patent application or granted ep patent |
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| 18D | Application deemed to be withdrawn |
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