[go: up one dir, main page]

EP3813698A4 - Méthode et appareil pour le traitement de fractures osseuses, et/ou pour la fortification et/ou l'augmentation de la masse osseuse, notamment l'apport et l'utilisation d'implants composites, et nouvelles structures composites pouvant être utilisées pour des applications médicales et non médicales - Google Patents

Méthode et appareil pour le traitement de fractures osseuses, et/ou pour la fortification et/ou l'augmentation de la masse osseuse, notamment l'apport et l'utilisation d'implants composites, et nouvelles structures composites pouvant être utilisées pour des applications médicales et non médicales Download PDF

Info

Publication number
EP3813698A4
EP3813698A4 EP19798937.9A EP19798937A EP3813698A4 EP 3813698 A4 EP3813698 A4 EP 3813698A4 EP 19798937 A EP19798937 A EP 19798937A EP 3813698 A4 EP3813698 A4 EP 3813698A4
Authority
EP
European Patent Office
Prior art keywords
medical
fortification
augmentation
delivery
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19798937.9A
Other languages
German (de)
English (en)
Other versions
EP3813698A1 (fr
Inventor
Jeffrey A. D'agostino
Werner Blank
Charles HEGEDUS
Sandip Agarwal
Elizabeth Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
206 Ortho Inc
Original Assignee
206 Ortho Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/025,639 external-priority patent/US11351261B2/en
Priority claimed from US16/040,164 external-priority patent/US10517654B2/en
Application filed by 206 Ortho Inc filed Critical 206 Ortho Inc
Publication of EP3813698A1 publication Critical patent/EP3813698A1/fr
Publication of EP3813698A4 publication Critical patent/EP3813698A4/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
    • A61B17/7097—Stabilisers comprising fluid filler in an implant, e.g. balloon; devices for inserting or filling such implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A61B17/7233—Intramedullary devices, e.g. pins or nails with special means of locking the nail to the bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A61B17/7233—Intramedullary devices, e.g. pins or nails with special means of locking the nail to the bone
    • A61B17/7258—Intramedullary devices, e.g. pins or nails with special means of locking the nail to the bone with laterally expanding parts, e.g. for gripping the bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30965—Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A61B17/7291—Intramedullary devices, e.g. pins or nails for small bones, e.g. in the foot, ankle, hand or wrist
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8897—Guide wires or guide pins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00526—Methods of manufacturing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00964—Material properties composite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2892—Tibia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Manufacturing & Machinery (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
EP19798937.9A 2018-05-09 2019-05-09 Méthode et appareil pour le traitement de fractures osseuses, et/ou pour la fortification et/ou l'augmentation de la masse osseuse, notamment l'apport et l'utilisation d'implants composites, et nouvelles structures composites pouvant être utilisées pour des applications médicales et non médicales Pending EP3813698A4 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862669271P 2018-05-09 2018-05-09
US16/025,639 US11351261B2 (en) 2010-10-20 2018-07-02 Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
US16/040,164 US10517654B2 (en) 2010-10-20 2018-07-19 Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
PCT/US2019/031617 WO2019217748A1 (fr) 2018-05-09 2019-05-09 Méthode et appareil pour le traitement de fractures osseuses, et/ou pour la fortification et/ou l'augmentation de la masse osseuse, notamment l'apport et l'utilisation d'implants composites, et nouvelles structures composites pouvant être utilisées pour des applications médicales et non médicales

Publications (2)

Publication Number Publication Date
EP3813698A1 EP3813698A1 (fr) 2021-05-05
EP3813698A4 true EP3813698A4 (fr) 2022-06-01

Family

ID=68468384

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19798937.9A Pending EP3813698A4 (fr) 2018-05-09 2019-05-09 Méthode et appareil pour le traitement de fractures osseuses, et/ou pour la fortification et/ou l'augmentation de la masse osseuse, notamment l'apport et l'utilisation d'implants composites, et nouvelles structures composites pouvant être utilisées pour des applications médicales et non médicales

Country Status (3)

Country Link
US (1) US20210308264A1 (fr)
EP (1) EP3813698A4 (fr)
WO (1) WO2019217748A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL311092B2 (en) * 2018-08-31 2025-05-01 Wisconsin Alumni Res Found Fabrication of vascular grafts seeded with arterial endothelial cells
US11439445B2 (en) * 2019-03-19 2022-09-13 Dynorif, Llc Methods of bone reduction and fixation
US20230159698A1 (en) * 2020-04-07 2023-05-25 The Penn State Research Foundation Xylitol-doped citrate compositions and uses thereof
WO2022104114A1 (fr) * 2020-11-13 2022-05-19 206 Ortho, Inc. Composite allongé pour un implant
US20240074791A1 (en) * 2022-09-01 2024-03-07 MediCarbone, Inc. Systems and methods for bone repair and management using biocompatible polymeric resin

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100121463A1 (en) * 2005-04-27 2010-05-13 Bioretec Oy Bioabsorbable and bioactive composite material and a method for manufacturing the composite
US20160106838A1 (en) * 2013-05-23 2016-04-21 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
US20170246356A1 (en) * 2014-12-26 2017-08-31 Orahn Preiss-Bloom Continuous-fiber reinforced biocomposite medical implants

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6602293B1 (en) * 1996-11-01 2003-08-05 The Johns Hopkins University Polymeric composite orthopedic implant
US6210703B1 (en) * 1997-12-19 2001-04-03 Ppg Industries Ohio, Inc. Glass fiber chemical delivery system
CN102245115B (zh) * 2008-10-15 2016-08-24 史密夫和内修有限公司 复合内部固定架
US10525168B2 (en) * 2010-10-20 2020-01-07 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
CA2838017C (fr) * 2011-06-03 2019-08-27 DePuy Synthes Products, LLC Revetement metallique de soupape multicouche destine a un implant chirurgical

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100121463A1 (en) * 2005-04-27 2010-05-13 Bioretec Oy Bioabsorbable and bioactive composite material and a method for manufacturing the composite
US20160106838A1 (en) * 2013-05-23 2016-04-21 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
US20170246356A1 (en) * 2014-12-26 2017-08-31 Orahn Preiss-Bloom Continuous-fiber reinforced biocomposite medical implants

Also Published As

Publication number Publication date
US20210308264A1 (en) 2021-10-07
EP3813698A1 (fr) 2021-05-05
WO2019217748A1 (fr) 2019-11-14

Similar Documents

Publication Publication Date Title
EP3813698A4 (fr) Méthode et appareil pour le traitement de fractures osseuses, et/ou pour la fortification et/ou l'augmentation de la masse osseuse, notamment l'apport et l'utilisation d'implants composites, et nouvelles structures composites pouvant être utilisées pour des applications médicales et non médicales
ZA202103404B (en) Composition and method for treating the lungs
EP3781214A4 (fr) Compositions et procédés de traitement de l'amyotrophie spinale
PH12018502634A1 (en) Topical compositions of apremilast
EA201791702A1 (ru) Терапевтические средства на основе гликанов и связанные с ними способы
JP2014139220A5 (fr)
EP3429536A4 (fr) Traitement de l'ostéopénie et de l'ostéoporose et stimulation de la croissance osseuse
EP3684378A4 (fr) Gapmères et procédés d'utilisation de ces derniers pour le traitement de la dystrophie musculaire
EP3413937A4 (fr) Compositions et procédés permettant la préparation de revêtements polymères composites sur des implants médicaux, et leur utilisation pour l'administration conjointe de multiples agents antimicrobiens
MA49794A (fr) Composition utilisée dans le traitement prophylactique et thérapeutique de troubles de l'appareil cardiovasculaire
CL2018000430A1 (es) Compuesto de hidroxitriazina y uso médico relacionado.
EP3876967A4 (fr) Microbiote thérapeutique pour le traitement et/ou la prévention d'une dysbiose
EP4255385A4 (fr) Composition(s) antigénique(s) et méthodes(s) d'utilisation contrepour la prévention et/ou le traitement d'une infection et/ou de maladies
EA201891610A1 (ru) Производные 3-(карбоксиэтил)-8-амино-2-оксо-1,3-диазаспиро[4.5]декана
MA39447A1 (fr) (s)-pirlindole ou ses sels pharmaceutiquement acceptables pour une utilisation en médecine
EP3344071A4 (fr) Compositions combinées pour réguler des niveaux de glycémie, l'hépatoprotection, et pour la prévention et le traitement d'états médicaux associés
EP3424563A4 (fr) Système et procédé de traitement par ultrasons de fractures, de lésions ostéo-musculo-tendineuses, de la douleur post-chirurgicale et de l'ostéonécrose dans les domaines de la médecine et de la médecine vétérinaire, ainsi que leurs applications
MA39448B1 (fr) (r)-pirlindole et ses sels pharmaceutiquement acceptables destinés à un usage médical
EP3549596A4 (fr) Utilisation de microcystines dans la préparation de médicaments pour la prévention ou le traitement de maladies de fibrose d'organe et de tissu
EP4606401A3 (fr) Système d'administration de médicament et procédé d'administration contrôlée et continue de médicaments dans le cerveau en contournant la barrière hémato-encéphalique
EP3391889A4 (fr) Composition pour le traitement de l'arthrose, comprenant de la sulfasalazine hydrophilisée et de l'acide hyaluronique et procédé de préparation de celle-ci
EP3962381A4 (fr) Dispositifs et procédés de traitement de fractures de stress vertébrales
EP3632447A4 (fr) Composition pharmaceutique pour la prévention ou le traitement d'une maladie osseuse
DE602004025103D1 (de) Heilkräuterzusammensetzung zur Behandlung von AIDS
PL423673A1 (pl) Kompozycja do podawania doustnego, zastosowanie kompozycji w zapobieganiu i leczeniu mucositis oraz sposób leczenia mucositis

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20201208

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A61L 27/58 20060101ALI20220128BHEP

Ipc: A61L 27/50 20060101ALI20220128BHEP

Ipc: A61L 27/48 20060101ALI20220128BHEP

Ipc: A61L 27/44 20060101ALI20220128BHEP

Ipc: A61L 27/00 20060101ALI20220128BHEP

Ipc: A61F 2/28 20060101ALI20220128BHEP

Ipc: A61B 17/80 20060101ALI20220128BHEP

Ipc: A61B 17/72 20060101ALI20220128BHEP

Ipc: A61B 17/70 20060101ALI20220128BHEP

Ipc: A61B 17/00 20060101AFI20220128BHEP

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Free format text: PREVIOUS MAIN CLASS: A61B0017700000

Ipc: A61B0017000000

A4 Supplementary search report drawn up and despatched

Effective date: 20220504

RIC1 Information provided on ipc code assigned before grant

Ipc: A61L 27/58 20060101ALI20220428BHEP

Ipc: A61L 27/50 20060101ALI20220428BHEP

Ipc: A61L 27/48 20060101ALI20220428BHEP

Ipc: A61L 27/44 20060101ALI20220428BHEP

Ipc: A61L 27/00 20060101ALI20220428BHEP

Ipc: A61F 2/28 20060101ALI20220428BHEP

Ipc: A61B 17/80 20060101ALI20220428BHEP

Ipc: A61B 17/72 20060101ALI20220428BHEP

Ipc: A61B 17/70 20060101ALI20220428BHEP

Ipc: A61B 17/00 20060101AFI20220428BHEP

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230519

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20250324