EP3801552A4 - Composition et procédé d'inhalation - Google Patents

Composition et procédé d'inhalation Download PDF

Info

Publication number: EP3801552A4
Authority: EP; European Patent Office
Prior art keywords: inhalation; composition
Prior art date: 2018-06-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

EP19815062.5A

Other languages

German (de)

English (en)

Other versions

EP3801552A1 (fr

Inventor

Joseph J. Guarneri

Nikhil AMIN

Marshall L. Grant

John J. Freeman

Kelly S. Kraft

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Mannkind Corp

Original Assignee

Mannkind Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-06-07

Filing date

2019-06-07

Publication date

2022-02-23

2019-06-07 Application filed by Mannkind Corp filed Critical Mannkind Corp

2021-04-14 Publication of EP3801552A1 publication Critical patent/EP3801552A1/fr

2022-02-23 Publication of EP3801552A4 publication Critical patent/EP3801552A4/fr

Status Pending legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Otolaryngology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

EP19815062.5A 2018-06-07 2019-06-07 Composition et procédé d'inhalation Pending EP3801552A4 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201862682109P	2018-06-07	2018-06-07
PCT/US2019/036095 WO2019237028A1 (fr)	2018-06-07	2019-06-07	Composition et procédé d'inhalation

Publications (2)

Publication Number	Publication Date
EP3801552A1 EP3801552A1 (fr)	2021-04-14
EP3801552A4 true EP3801552A4 (fr)	2022-02-23

Family

ID=68770678

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19815062.5A Pending EP3801552A4 (fr)	2018-06-07	2019-06-07	Composition et procédé d'inhalation

Country Status (5)

Country	Link
EP (1)	EP3801552A4 (fr)
JP (1)	JP2021527058A (fr)
AU (2)	AU2019282808B2 (fr)
CA (1)	CA3102967A1 (fr)
WO (1)	WO2019237028A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP3808731A1 (fr)	2013-10-25	2021-04-21	Insmed Incorporated	Composés de prostacycline
WO2017192993A1 (fr)	2016-05-05	2017-11-09	Liquidia Technologies, Inc.	Poudre sèche de tréprostinil pour le traitement de l'hypertension pulmonaire
US11458098B2 (en)	2019-04-29	2022-10-04	Insmed Incorporated	Dry powder compositions of treprostinil prodrugs and methods of use thereof
US11826327B2 (en)	2020-04-17	2023-11-28	United Therapeutics Corporation	Treatment for interstitial lung disease
WO2021252446A1 (fr)	2020-06-09	2021-12-16	United Therapeutics Corporation	Promédicaments à base de fumaryle dicétopipéridine de tréprostinil
KR20230096998A (ko) *	2020-10-28	2023-06-30	인스메드 인코포레이티드	트레프로스티닐 전구약물의 건조 분말 조성물 및 이의 사용 방법
CA3199324A1 (fr)	2020-11-17	2022-05-27	Adam Marc Silverstein	Imatinib inhale pour le domaine de l'hypertension pulmonaire
IL303431A (en) *	2020-12-07	2023-08-01	Mannkind Corp	Method and composition for the treatment of pulmonary fibrosis
AU2022229367A1 (en)	2021-03-03	2023-09-14	United Therapeutics Corporation	A dry powder composition of trestinil and its prodrug thereof and further comprising comprising (e)-3,6-bis[4-(n-carbonyl-2-propenyl)amidobutyl]-2,5-diketopiperazine (fdkp)
IL312346A (en) *	2021-10-27	2024-06-01	Mannkind Corp	Preparations for the treatment of pulmonary hypertension
KR20240141319A (ko)	2022-02-08	2024-09-26	유나이티드 쎄러퓨틱스 코포레이션	트레프로스티닐 일로프로스트 조합 치료 요법
WO2025160403A1 (fr) *	2024-01-24	2025-07-31	Mannkind Corporation	Système de transport de poudre

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20140199398A1 (en) *	2011-06-17	2014-07-17	Mannkind Corporation	High capacity diektopiperazine microparticles and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5352461A (en) *	1992-03-11	1994-10-04	Pharmaceutical Discovery Corporation	Self assembling diketopiperazine drug delivery system
KR101486829B1 (ko) *	2005-09-14	2015-01-29	맨카인드 코포레이션	결정질 미립자 표면에 대한 활성제의 친화력의 증가를 기반으로 하는 약물 제제의 방법
EP2970149B1 (fr) *	2013-03-15	2019-08-21	MannKind Corporation	Compositions de dicétopipérazine microcristallines et procédés
AU2017211410B2 (en) *	2016-01-29	2022-10-13	Mannkind Corporation	Dry powder inhaler
WO2017192993A1 (fr) *	2016-05-05	2017-11-09	Liquidia Technologies, Inc.	Poudre sèche de tréprostinil pour le traitement de l'hypertension pulmonaire

2019
- 2019-06-07 AU AU2019282808A patent/AU2019282808B2/en active Active
- 2019-06-07 EP EP19815062.5A patent/EP3801552A4/fr active Pending
- 2019-06-07 JP JP2020567883A patent/JP2021527058A/ja active Pending
- 2019-06-07 CA CA3102967A patent/CA3102967A1/fr active Pending
- 2019-06-07 WO PCT/US2019/036095 patent/WO2019237028A1/fr not_active Ceased
2025
- 2025-03-21 AU AU2025202053A patent/AU2025202053A1/en not_active Abandoned

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20140199398A1 (en) *	2011-06-17	2014-07-17	Mannkind Corporation	High capacity diektopiperazine microparticles and methods

Also Published As

Publication number	Publication date
AU2025202053A1 (en)	2025-04-10
WO2019237028A1 (fr)	2019-12-12
JP2021527058A (ja)	2021-10-11
AU2019282808A1 (en)	2021-01-07
CA3102967A1 (fr)	2019-12-12
AU2019282808B2 (en)	2025-03-20
EP3801552A1 (fr)	2021-04-14

Publication	Publication Date	Title
EP3801552A4 (fr)	2022-02-23	Composition et procédé d'inhalation
EP3850088A4 (fr)	2023-07-19	Compositions et procédés d'amélioration de l'édition de base
EP3894343A4 (fr)	2022-08-31	Procédés et compositions pour l'administration de dioxyde de carbone
EP3866924A4 (fr)	2022-07-06	Compositions et procédés d'administration d'anticorps
EP3704239A4 (fr)	2021-08-18	Compositions de casz et procédés d'utilisation
EP3490622C0 (fr)	2023-09-06	Méthodes et compositions utilisées pour la cicatrisation
EP3704254A4 (fr)	2021-09-01	Compositions de cas12c et procédés d'utilisation
EP3445251A4 (fr)	2020-05-13	Dispositifs de biopsie et leurs procédés d'utilisation
EP3844553C0 (fr)	2025-10-01	Procédé et système d'estimation du regard
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EP3599854A4 (fr)	2020-12-23	Pyrrolidinones et procédé pour les préparer
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EP3720378C0 (fr)	2024-11-06	Cathéter et procédé d'assemblage de cathéter
EP3733650C0 (fr)	2024-08-28	Procédé de préparation d'un intermédiaire d'élagolix et composition associée
EP3796894A4 (fr)	2022-05-04	Procédés et compositions pour l'édition génomique
EP3710588A4 (fr)	2021-08-18	Compositions et méthodes pour inhiber l'expression de l'aldh2
EP3851466A4 (fr)	2021-11-24	Polyoxyméthylène et son procédé de production
EP3506982A4 (fr)	2020-07-22	Inhibiteurs de mif et leurs méthodes d'utilisation
EP3687628A4 (fr)	2021-09-22	Compositions et méthodes pour inhiber acss2
EP3579966C0 (fr)	2024-12-11	Composition de sorbant et méthode de fabrication

Legal Events

Date	Code	Title	Description
2019-12-14	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2021-03-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2021-03-12	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2021-04-14	17P	Request for examination filed	Effective date: 20201214
2021-04-14	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2021-04-14	AX	Request for extension of the european patent	Extension state: BA ME
2021-09-15	DAV	Request for validation of the european patent (deleted)
2021-09-15	DAX	Request for extension of the european patent (deleted)
2021-12-17	REG	Reference to a national code	Ref country code: HK Ref legal event code: DE Ref document number: 40049543 Country of ref document: HK
2022-02-23	A4	Supplementary search report drawn up and despatched	Effective date: 20220124
2022-02-23	RIC1	Information provided on ipc code assigned before grant	Ipc: A61M 15/00 20060101ALI20220118BHEP Ipc: A61K 31/5575 20060101ALI20220118BHEP Ipc: A61K 9/16 20060101ALI20220118BHEP Ipc: A61K 9/48 20060101ALI20220118BHEP Ipc: A61K 9/00 20060101ALI20220118BHEP Ipc: A61K 31/557 20060101AFI20220118BHEP
2023-06-14	P01	Opt-out of the competence of the unified patent court (upc) registered	Effective date: 20230506
2024-02-01	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: EXAMINATION IS IN PROGRESS
2024-03-06	17Q	First examination report despatched	Effective date: 20240131