EP3843721A4 - Compositions ophtalmiques et méthodes d'utilisation - Google Patents
Compositions ophtalmiques et méthodes d'utilisation Download PDFInfo
- Publication number
- EP3843721A4 EP3843721A4 EP19856338.9A EP19856338A EP3843721A4 EP 3843721 A4 EP3843721 A4 EP 3843721A4 EP 19856338 A EP19856338 A EP 19856338A EP 3843721 A4 EP3843721 A4 EP 3843721A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- ophthalmic compositions
- ophthalmic
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16/116,872 US20190008920A1 (en) | 2017-05-19 | 2018-08-29 | Ophthalmic compositions and methods of use |
| PCT/US2019/048721 WO2020047197A1 (fr) | 2018-08-29 | 2019-08-29 | Compositions ophtalmiques et méthodes d'utilisation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3843721A1 EP3843721A1 (fr) | 2021-07-07 |
| EP3843721A4 true EP3843721A4 (fr) | 2022-10-12 |
Family
ID=69644699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP19856338.9A Withdrawn EP3843721A4 (fr) | 2018-08-29 | 2019-08-29 | Compositions ophtalmiques et méthodes d'utilisation |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3843721A4 (fr) |
| CN (1) | CN111212642A (fr) |
| CA (1) | CA3115664A1 (fr) |
| WO (1) | WO2020047197A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024042550A1 (fr) * | 2022-08-25 | 2024-02-29 | Sentiss Pharma Private Limited | Composition de combinaison ophtalmique |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070225217A1 (en) * | 2005-11-09 | 2007-09-27 | Combinatorx, Incorporated | Methods, compositions, and kits for the treatment of medical conditions |
| EP1827373B1 (fr) * | 2004-11-09 | 2008-12-03 | Novagali Pharma SA | Émulsions ophtalmiques contenant des prostaglandines |
| AU2012351948A1 (en) * | 2011-12-16 | 2014-07-10 | Allergan, Inc. | Ophthalmic compositions comprising polyvinyl capralactam - polyvinyl acetate - polyethylene glycol graft copolymer |
| US9034830B2 (en) * | 2009-10-30 | 2015-05-19 | Intratus, Inc. | Methods and compositions for sustained delivery of drugs |
| US9597328B2 (en) * | 2015-02-24 | 2017-03-21 | Ocugen, Inc. | Methods and compositions for treating dry eye disease and other eye disorders |
| US20170304316A1 (en) * | 2014-10-20 | 2017-10-26 | Sentiss Pharma Private Limited | Ophthalmic Solution |
| US20180055943A1 (en) * | 2016-08-23 | 2018-03-01 | Ira Jason Salzman | Ophthalmic lubricating spray |
| US20180153885A1 (en) * | 2015-02-24 | 2018-06-07 | The Board Of Trustees Of The University Of Illinois | Preservative free ocular compositions and methods for using the same for treating dry eye disease and other eye disorders |
| WO2018139991A1 (fr) * | 2017-01-24 | 2018-08-02 | Macregen, Inc. | Traitement de la dégénérescence liée à l'âge et d'autres maladies oculaires avec des mimétiques d'apolipoprotéine |
| US20180221278A1 (en) * | 2015-02-24 | 2018-08-09 | Ocugen, Inc. | Prsustained release opthalmic formuation and methods for using the same |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2094688B1 (es) * | 1994-08-08 | 1997-08-01 | Cusi Lab | Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion. |
| US6569903B2 (en) * | 1999-12-07 | 2003-05-27 | Rohto Pharmaceutical Co., Ltd. | Ophthalmic compositions |
| MX2007010025A (es) * | 2007-08-17 | 2009-02-25 | Arturo Jimenez Bayardo | Composición farmacéutica para tratamiento de hipertensión ocular. |
| EP2664329A1 (fr) * | 2012-05-15 | 2013-11-20 | F. Holzer GmbH | Système de véhicule ophtalmologique |
| CN102895245A (zh) * | 2012-10-30 | 2013-01-30 | 河南牧翔动物药业有限公司 | 一种复方甲氧苄啶与盐酸多西环素纳米乳制剂及其制备方法 |
| US20170239331A1 (en) * | 2014-10-15 | 2017-08-24 | Rapid Pathogen Screening, Inc. | Formulations for histatin protectives and therapeutics |
| MX2019003623A (es) * | 2016-09-28 | 2019-09-23 | Medicon Pharmaceuticals Inc | Composiciones y metodos para el tratamiento de afecciones oftalmicas. |
-
2019
- 2019-08-29 CN CN201980001967.2A patent/CN111212642A/zh active Pending
- 2019-08-29 CA CA3115664A patent/CA3115664A1/fr active Pending
- 2019-08-29 EP EP19856338.9A patent/EP3843721A4/fr not_active Withdrawn
- 2019-08-29 WO PCT/US2019/048721 patent/WO2020047197A1/fr not_active Ceased
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1827373B1 (fr) * | 2004-11-09 | 2008-12-03 | Novagali Pharma SA | Émulsions ophtalmiques contenant des prostaglandines |
| US20070225217A1 (en) * | 2005-11-09 | 2007-09-27 | Combinatorx, Incorporated | Methods, compositions, and kits for the treatment of medical conditions |
| US9034830B2 (en) * | 2009-10-30 | 2015-05-19 | Intratus, Inc. | Methods and compositions for sustained delivery of drugs |
| AU2012351948A1 (en) * | 2011-12-16 | 2014-07-10 | Allergan, Inc. | Ophthalmic compositions comprising polyvinyl capralactam - polyvinyl acetate - polyethylene glycol graft copolymer |
| US20170304316A1 (en) * | 2014-10-20 | 2017-10-26 | Sentiss Pharma Private Limited | Ophthalmic Solution |
| US9597328B2 (en) * | 2015-02-24 | 2017-03-21 | Ocugen, Inc. | Methods and compositions for treating dry eye disease and other eye disorders |
| US20180153885A1 (en) * | 2015-02-24 | 2018-06-07 | The Board Of Trustees Of The University Of Illinois | Preservative free ocular compositions and methods for using the same for treating dry eye disease and other eye disorders |
| US20180221278A1 (en) * | 2015-02-24 | 2018-08-09 | Ocugen, Inc. | Prsustained release opthalmic formuation and methods for using the same |
| US20180055943A1 (en) * | 2016-08-23 | 2018-03-01 | Ira Jason Salzman | Ophthalmic lubricating spray |
| WO2018139991A1 (fr) * | 2017-01-24 | 2018-08-02 | Macregen, Inc. | Traitement de la dégénérescence liée à l'âge et d'autres maladies oculaires avec des mimétiques d'apolipoprotéine |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO2020047197A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN111212642A (zh) | 2020-05-29 |
| CA3115664A1 (fr) | 2020-03-05 |
| EP3843721A1 (fr) | 2021-07-07 |
| WO2020047197A1 (fr) | 2020-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
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| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
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| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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Effective date: 20210329 |
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| AK | Designated contracting states |
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|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 27/02 20060101ALI20220602BHEP Ipc: A61K 9/107 20060101ALI20220602BHEP Ipc: A61K 31/436 20060101ALI20220602BHEP Ipc: A61K 31/56 20060101ALI20220602BHEP Ipc: A61K 31/4725 20060101ALI20220602BHEP Ipc: A61K 38/13 20060101ALI20220602BHEP Ipc: A61K 31/498 20060101ALI20220602BHEP Ipc: A61K 31/137 20060101ALI20220602BHEP Ipc: A61K 47/32 20060101ALI20220602BHEP Ipc: A61K 47/18 20170101ALI20220602BHEP Ipc: A61K 47/12 20060101ALI20220602BHEP Ipc: A61K 47/10 20170101ALI20220602BHEP Ipc: A61K 47/26 20060101ALI20220602BHEP Ipc: A61K 47/44 20170101ALI20220602BHEP Ipc: A61K 31/573 20060101ALI20220602BHEP Ipc: A61K 31/407 20060101ALI20220602BHEP Ipc: A61K 9/08 20060101ALI20220602BHEP Ipc: A61K 9/00 20060101ALI20220602BHEP Ipc: A61K 31/417 20060101AFI20220602BHEP |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20220913 |
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| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 27/02 20060101ALI20220907BHEP Ipc: A61K 9/107 20060101ALI20220907BHEP Ipc: A61K 31/436 20060101ALI20220907BHEP Ipc: A61K 31/56 20060101ALI20220907BHEP Ipc: A61K 31/4725 20060101ALI20220907BHEP Ipc: A61K 38/13 20060101ALI20220907BHEP Ipc: A61K 31/498 20060101ALI20220907BHEP Ipc: A61K 31/137 20060101ALI20220907BHEP Ipc: A61K 47/32 20060101ALI20220907BHEP Ipc: A61K 47/18 20170101ALI20220907BHEP Ipc: A61K 47/12 20060101ALI20220907BHEP Ipc: A61K 47/10 20170101ALI20220907BHEP Ipc: A61K 47/26 20060101ALI20220907BHEP Ipc: A61K 47/44 20170101ALI20220907BHEP Ipc: A61K 31/573 20060101ALI20220907BHEP Ipc: A61K 31/407 20060101ALI20220907BHEP Ipc: A61K 9/08 20060101ALI20220907BHEP Ipc: A61K 9/00 20060101ALI20220907BHEP Ipc: A61K 31/417 20060101AFI20220907BHEP |
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| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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| 18D | Application deemed to be withdrawn |
Effective date: 20230412 |