EP3681365A4 - Bioréacteur à grande échelle - Google Patents

Bioréacteur à grande échelle Download PDF

Info

Publication number: EP3681365A4
Authority: EP; European Patent Office
Prior art keywords: scale bioreactor; bioreactor; scale
Prior art date: 2017-09-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP18852871.5A

Other languages

German (de)

English (en)

Other versions

EP3681365A1 (fr

Inventor

Zongsen Wang

Wing Lau

Faribourz Payvandi

Peter Materna

Jadali AZADEH

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

3D Biotek LLC

Original Assignee

3D Biotek LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-09-11

Filing date

2018-09-11

Publication date

2021-06-16

2018-09-11 Application filed by 3D Biotek LLC filed Critical 3D Biotek LLC

2020-07-22 Publication of EP3681365A1 publication Critical patent/EP3681365A1/fr

2021-06-16 Publication of EP3681365A4 publication Critical patent/EP3681365A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/58—Reaction vessels connected in series or in parallel
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/14—Scaffolds; Matrices
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/08—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by vibration
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
- C12M37/02—Filters
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Microbiology (AREA)
Sustainable Development (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Analytical Chemistry (AREA)
Immunology (AREA)
Clinical Laboratory Science (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

EP18852871.5A 2017-09-11 2018-09-11 Bioréacteur à grande échelle Withdrawn EP3681365A4 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201762556646P	2017-09-11	2017-09-11
US201862636039P	2018-02-27	2018-02-27
PCT/US2018/050467 WO2019051486A1 (fr)	2017-09-11	2018-09-11	Bioréacteur à grande échelle

Publications (2)

Publication Number	Publication Date
EP3681365A1 EP3681365A1 (fr)	2020-07-22
EP3681365A4 true EP3681365A4 (fr)	2021-06-16

Family

ID=65634631

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP18852871.5A Withdrawn EP3681365A4 (fr)	2017-09-11	2018-09-11	Bioréacteur à grande échelle

Country Status (3)

Country	Link
EP (1)	EP3681365A4 (fr)
CN (1)	CN111132595A (fr)
WO (1)	WO2019051486A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP3504315A4 (fr) *	2016-08-27	2020-04-15	3D Biotek, LLC	Bioréacteur
EP4301842A1 (fr) *	2021-03-26	2024-01-10	TERUMO Kabushiki Kaisha	Système de culture cellulaire
WO2022202732A1 (fr) *	2021-03-26	2022-09-29	Terumo Kabushiki Kaisha	Système de culture cellulaire

Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2314343A (en) *	1996-06-18	1997-12-24	Liau Ming Yi	Apparatus for intermittently exposing cells during culture
CN1560225A (zh) *	2004-03-01	2005-01-05	华东理工大学	双层活性皮肤体外构建的灌注式生物反应器系统
US20060110822A1 (en) *	2004-09-16	2006-05-25	Robbins Neil F	Perfusion bioreactors for culturing cells
WO2011142670A1 (fr) *	2010-05-12	2011-11-17	Xpand Biotechnology B.V.	Poche pour culture cellulaire
WO2015132729A1 (fr) *	2014-03-04	2015-09-11	Pluristem Ltd.	Systèmes et procédés de culture et de collecte de cellules
WO2017143640A1 (fr) *	2016-02-26	2017-08-31	广州洁特生物过滤股份有限公司	Appareil et procédé de culture cellulaire

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI233449B (en) *	1999-07-01	2005-06-01	Ind Tech Res Inst	High efficient cell-cultivating device
US6875605B1 (en) *	2002-08-21	2005-04-05	Florida State University Research Foundation, Inc.	Modular cell culture bioreactor and associated methods
CN102112593A (zh) *	2008-08-01	2011-06-29	智能生物系统公司	生物反应器平台的腔室
PT104155B (pt) *	2008-08-06	2017-04-05	Ass For The Advancement Of Tissue Eng And Cell Based Tech & Therapies (A4Tec)	Bioreactor multi-câmara com perfusão bidireccional integrado num sistema de cultura para aplicação em estratégias de engenharia de tecidos
JP2013510590A (ja) *	2009-11-17	2013-03-28	ハーバードバイオサイエンスインコーポレーテッド	臓器を形成および／または分析するためのバイオリアクタ、システムおよび方法
CN102296029B (zh) *	2010-06-28	2013-01-30	裴国献	灌注式生物反应器系统
CN103298922B (zh) *	2011-03-29	2014-11-19	南京新诺丹生物技术有限公司	细胞分选和培养的多功能生物反应器系统与方法
AU2012241521B2 (en) *	2011-04-15	2016-07-14	Pluri Biotech Ltd	Methods and systems for harvesting cells
BR102012033604A2 (pt) *	2012-12-28	2014-08-19	Univ Minas Gerais	Câmara de perfusão de cultivo tridimensional para a engenharia de tecidos
KR102147010B1 (ko) *	2013-10-30	2020-08-21	밀리차 라디식	3차원 조직 배양을 위한 장치 및 방법

2018
- 2018-09-11 WO PCT/US2018/050467 patent/WO2019051486A1/fr not_active Ceased
- 2018-09-11 EP EP18852871.5A patent/EP3681365A4/fr not_active Withdrawn
- 2018-09-11 CN CN201880059387.4A patent/CN111132595A/zh active Pending

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2314343A (en) *	1996-06-18	1997-12-24	Liau Ming Yi	Apparatus for intermittently exposing cells during culture
CN1560225A (zh) *	2004-03-01	2005-01-05	华东理工大学	双层活性皮肤体外构建的灌注式生物反应器系统
US20060110822A1 (en) *	2004-09-16	2006-05-25	Robbins Neil F	Perfusion bioreactors for culturing cells
WO2011142670A1 (fr) *	2010-05-12	2011-11-17	Xpand Biotechnology B.V.	Poche pour culture cellulaire
WO2015132729A1 (fr) *	2014-03-04	2015-09-11	Pluristem Ltd.	Systèmes et procédés de culture et de collecte de cellules
WO2017143640A1 (fr) *	2016-02-26	2017-08-31	广州洁特生物过滤股份有限公司	Appareil et procédé de culture cellulaire

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2019051486A1 *

Also Published As

Publication number	Publication date
WO2019051486A1 (fr)	2019-03-14
EP3681365A1 (fr)	2020-07-22
CN111132595A (zh)	2020-05-08

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Legal Events

Date	Code	Title	Description
2019-03-16	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2020-06-19	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2020-06-19	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2020-07-22	17P	Request for examination filed	Effective date: 20200408
2020-07-22	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2020-07-22	AX	Request for extension of the european patent	Extension state: BA ME
2020-12-16	DAV	Request for validation of the european patent (deleted)
2020-12-16	DAX	Request for extension of the european patent (deleted)
2021-06-16	A4	Supplementary search report drawn up and despatched	Effective date: 20210514
2021-06-16	RIC1	Information provided on ipc code assigned before grant	Ipc: A61B 1/00 20060101AFI20210508BHEP Ipc: A61B 5/00 20060101ALI20210508BHEP Ipc: A61L 27/00 20060101ALI20210508BHEP Ipc: C12M 1/00 20060101ALI20210508BHEP Ipc: C12M 1/12 20060101ALI20210508BHEP Ipc: C12M 1/32 20060101ALI20210508BHEP Ipc: C12M 1/34 20060101ALI20210508BHEP Ipc: C12M 1/26 20060101ALI20210508BHEP
2022-05-06	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2022-06-08	18D	Application deemed to be withdrawn	Effective date: 20211114