EP3532038A4 - METHOD FOR MANAGING PAIN BY MEANS OF DEVMEDETOMIDINE TRANSDERMAL ADMINISTRATION DEVICES - Google Patents

METHOD FOR MANAGING PAIN BY MEANS OF DEVMEDETOMIDINE TRANSDERMAL ADMINISTRATION DEVICES Download PDF

Info

Publication number: EP3532038A4
Authority: EP; European Patent Office
Prior art keywords: devmedetomidine; transdermal administration; administration devices; managing pain; pain
Prior art date: 2016-10-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

EP17865069.3A

Other languages

German (de)

French (fr)

Other versions

EP3532038A2 (en

Inventor

Rose Marie GONSALVES

Jutaro Shudo

Wan-Ning SONG

Stephen Shipping HWANG

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Teikoku Pharma USA Inc

Original Assignee

Teikoku Pharma USA Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-10-31

Filing date

2017-10-31

Publication date

2020-06-03

2017-10-31 Application filed by Teikoku Pharma USA Inc filed Critical Teikoku Pharma USA Inc

2019-09-04 Publication of EP3532038A2 publication Critical patent/EP3532038A2/en

2020-06-03 Publication of EP3532038A4 publication Critical patent/EP3532038A4/en

Status Pending legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP17865069.3A 2016-10-31 2017-10-31 METHOD FOR MANAGING PAIN BY MEANS OF DEVMEDETOMIDINE TRANSDERMAL ADMINISTRATION DEVICES Pending EP3532038A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201662415248P	2016-10-31	2016-10-31
US201762547582P	2017-08-18	2017-08-18
PCT/US2017/059357 WO2018081812A2 (en)	2016-10-31	2017-10-31	Methods of managing pain using dexmedetomidine transdermal delivery devices

Publications (2)

Publication Number	Publication Date
EP3532038A2 EP3532038A2 (en)	2019-09-04
EP3532038A4 true EP3532038A4 (en)	2020-06-03

Family

ID=62020311

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP17865069.3A Pending EP3532038A4 (en)	2016-10-31	2017-10-31	METHOD FOR MANAGING PAIN BY MEANS OF DEVMEDETOMIDINE TRANSDERMAL ADMINISTRATION DEVICES

Country Status (10)

Country	Link
US (1)	US20180117012A1 (en)
EP (1)	EP3532038A4 (en)
JP (3)	JP2019534288A (en)
KR (4)	KR20210113439A (en)
CN (1)	CN110022865A (en)
BR (1)	BR112019006955A2 (en)
CA (1)	CA3038354C (en)
RU (1)	RU2723761C1 (en)
TW (1)	TWI764951B (en)
WO (1)	WO2018081812A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20210113439A (en) *	2016-10-31	2021-09-15	테이코쿠 팔마 유에스에이, 인코포레이티드	Methods of Managing Pain Using Dexmedetomidine Transdermal Delivery Devices
CN110087641B (en)	2016-12-20	2024-03-12	罗曼治疗系统股份公司	Transdermal therapeutic systems containing asenapine and polysiloxane or polyisobutylene
KR102506333B1 (en)	2016-12-20	2023-03-06	에르테에스 로만 테라피-시스테메 아게	Transdermal absorption treatment system containing asenapine
CA3045043A1 (en)	2016-12-31	2018-07-05	Bioxcel Therapeutics, Inc.	Use of sublingual dexmedetomidine for the treatment of agitation
CN112533593A (en) *	2018-06-20	2021-03-19	罗曼治疗系统股份公司	Transdermal therapeutic system comprising asenapine
CN115154440A (en)	2018-06-27	2022-10-11	比奥克斯塞尔医疗股份有限公司	Dexmedetomidine-containing film preparation and manufacturing method thereof
JP7453994B2 (en) *	2019-04-17	2024-03-21	エルテーエスローマンテラピー－ジステーメアーゲー	Transdermal treatment system
WO2021016112A2 (en)	2019-07-19	2021-01-28	Bioxcel Therapeutics, Inc.	Non-sedating dexmedetomidine treatment regimens
WO2021026377A1 (en) *	2019-08-07	2021-02-11	Alkermes, Inc.	Lactam-containing compounds for the treatment of pain
WO2021026378A1 (en) *	2019-08-07	2021-02-11	Alkermes, Inc.	Indole compounds for the treatment of pain
WO2021026375A1 (en) *	2019-08-07	2021-02-11	Alkermes, Inc.	Fused bicyclic compounds for the treatment of pain
WO2021026380A1 (en) *	2019-08-07	2021-02-11	Alkermes, Inc.	Phenyltriazole compounds for the treatment of pain
CN111281850A (en) *	2020-03-14	2020-06-16	周琛	Analgesic pharmaceutical composition and use thereof
CN116098876A (en) *	2021-11-11	2023-05-12	北京泰德制药股份有限公司	Dexmedetomidine transdermal patch as well as preparation method and application thereof
WO2024037545A1 (en) *	2022-08-17	2024-02-22	宜昌人福药业有限责任公司	Dexmedetomidine transdermal composition, transdermal patch, and method for preparing transdermal patch and use thereof
US11806334B1 (en)	2023-01-12	2023-11-07	Bioxcel Therapeutics, Inc.	Non-sedating dexmedetomidine treatment regimens
US20250099399A1 (en) *	2023-09-05	2025-03-27	Teikoku Pharma Usa, Inc.	Transdermal delivery patch for treating pain

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20150098980A1 (en) *	2013-10-07	2015-04-09	Teikoku Pharma Usa, Inc.	Dexmedetomidine Transdermal Delivery Devices and Methods for Using the Same
US20150098982A1 (en) *	2013-10-07	2015-04-09	Teikoku Pharma Usa, Inc.	Methods and Compositions for Managing Pain Comprising Dexmedetomidine Transdermal Compositions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2215206B (en) *	1988-02-29	1991-07-03	Farmos Oy	4-substituted imidazole derivatives useful in perioperative care
US5124157A (en) *	1989-08-18	1992-06-23	Cygnus Therapeutic Systems	Method and device for administering dexmedetomidine transdermally
JP2819236B2 (en) *	1994-05-06	1998-10-30	日東電工株式会社	Transdermal formulation
AU4341401A (en) *	2000-03-10	2001-09-24	Durect Corp	Opioid formulations
US8629172B2 (en) *	2008-04-18	2014-01-14	Warsaw Orthopedic, Inc.	Methods and compositions for treating post-operative pain comprising clonidine
JP2011524345A (en) *	2008-06-04	2011-09-01	コーダセラピューティクス，インコーポレイテッド	Treatment of pain with gap junction modulating compounds
RU2012133969A (en) *	2010-01-08	2014-02-20	Рекро Фарма, Инк.	LOCAL TRANSDERMAL DEXMEDETOMIDINE COMPOSITIONS AND WAYS OF THEIR APPLICATION
US20130096170A1 (en) *	2011-10-14	2013-04-18	Hospira, Inc.	Methods of treating pediatric patients using dexmedetomidine
US11547676B2 (en) *	2012-12-28	2023-01-10	Teikoku Seiyaku Co., Ltd.	Extended buprenorphine transdermal delivery compositions and methods for using the same
WO2015054063A1 (en) *	2013-10-07	2015-04-16	Teikoku Pharma Usa, Inc.	Methods and compositions for treating withdrawal syndromes using non-sedative dexmedetomidine transdermal compositions
CN105764496B (en) *	2013-10-07	2020-09-25	帝国制药美国公司	Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine
JP6469587B2 (en) *	2013-12-18	2019-02-13	丸石製薬株式会社	Water-containing patch
KR20210113439A (en) *	2016-10-31	2021-09-15	테이코쿠 팔마 유에스에이, 인코포레이티드	Methods of Managing Pain Using Dexmedetomidine Transdermal Delivery Devices

2017
- 2017-10-31 KR KR1020217028734A patent/KR20210113439A/en not_active Ceased
- 2017-10-31 JP JP2019522825A patent/JP2019534288A/en not_active Withdrawn
- 2017-10-31 WO PCT/US2017/059357 patent/WO2018081812A2/en not_active Ceased
- 2017-10-31 KR KR1020197014883A patent/KR20190060007A/en not_active Ceased
- 2017-10-31 BR BR112019006955A patent/BR112019006955A2/en not_active Application Discontinuation
- 2017-10-31 RU RU2019109873A patent/RU2723761C1/en active
- 2017-10-31 KR KR1020257021141A patent/KR20250105683A/en active Pending
- 2017-10-31 EP EP17865069.3A patent/EP3532038A4/en active Pending
- 2017-10-31 CA CA3038354A patent/CA3038354C/en active Active
- 2017-10-31 TW TW106137654A patent/TWI764951B/en active
- 2017-10-31 CN CN201780072175.5A patent/CN110022865A/en active Pending
- 2017-10-31 US US15/799,602 patent/US20180117012A1/en active Pending
- 2017-10-31 KR KR1020237010276A patent/KR20230048156A/en not_active Ceased
2022
- 2022-12-23 JP JP2022206760A patent/JP2023036825A/en not_active Withdrawn
2025
- 2025-04-23 JP JP2025071090A patent/JP2025108704A/en active Pending

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20150098980A1 (en) *	2013-10-07	2015-04-09	Teikoku Pharma Usa, Inc.	Dexmedetomidine Transdermal Delivery Devices and Methods for Using the Same
US20150098982A1 (en) *	2013-10-07	2015-04-09	Teikoku Pharma Usa, Inc.	Methods and Compositions for Managing Pain Comprising Dexmedetomidine Transdermal Compositions

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHAOLIANG TANG ET AL: "Dexmedetomidine in perioperative acute pain management: a non-opioid adjuvant analgesic", JOURNAL OF PAIN RESEARCH, vol. Volume 10, 1 August 2017 (2017-08-01), pages 1899 - 1904, XP055689172, DOI: 10.2147/JPR.S139387 *
LUISE JESSEN LUNDORF ET AL: "Perioperative dexmedetomidine for acute pain after abdominal surgery in adults", COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 18 February 2016 (2016-02-18), XP055689178, DOI: 10.1002/14651858.CD010358.pub2 *
See also references of WO2018081812A2 *

Also Published As

Publication number	Publication date
KR20250105683A (en)	2025-07-08
TW201817419A (en)	2018-05-16
KR20230048156A (en)	2023-04-10
CN110022865A (en)	2019-07-16
WO2018081812A2 (en)	2018-05-03
BR112019006955A2 (en)	2019-07-02
US20180117012A1 (en)	2018-05-03
CA3038354A1 (en)	2018-05-03
TWI764951B (en)	2022-05-21
RU2723761C1 (en)	2020-06-17
JP2025108704A (en)	2025-07-23
KR20190060007A (en)	2019-05-31
JP2023036825A (en)	2023-03-14
KR20210113439A (en)	2021-09-15
JP2019534288A (en)	2019-11-28
WO2018081812A3 (en)	2019-01-17
CA3038354C (en)	2021-08-17
EP3532038A2 (en)	2019-09-04

Publication	Publication Date	Title
EP3532038A4 (en)	2020-06-03	METHOD FOR MANAGING PAIN BY MEANS OF DEVMEDETOMIDINE TRANSDERMAL ADMINISTRATION DEVICES
EP3463248A4 (en)	2020-03-11	DEVICES AND METHOD FOR USING MEDICAL DEVICES
DE112016001203A5 (en)	2017-12-14	Method of estimating lanes
EP3534815A4 (en)	2020-07-08	METHOD AND DEVICES FOR POINTING TISSUE
EP3436139C0 (en)	2025-04-30	Method and device for administering therapeutics
EP3531899A4 (en)	2020-11-04	PROCEDURE FOR NEUROMODULATION
EP3177199C0 (en)	2025-04-23	MEDICAL DEVICES AND METHODS FOR POSITIONING
EP3742855C0 (en)	2025-04-09	PROCEDURES FOR MANAGING UPLINK TRANSFERS
EP3606962A4 (en)	2020-12-23	METHOD OF TREATMENT OF CD73HI TUMORS
EP3191005C0 (en)	2024-03-13	SYSTEMS AND METHODS FOR IMAGING AND MANIPULATION OF TISSUE
EP2891494A4 (en)	2016-04-27	METHOD FOR THE ADMINISTRATION OF HYPNOSIS / TREATMENT AGENTS
EP3672506A4 (en)	2021-05-26	DEVICE FOR EXTRACTION OF HEART LINES
EP3666888A4 (en)	2021-09-01	METHOD OF ACTIVATING T CELLS FOR CANCER TREATMENT
EP3427320A4 (en)	2020-06-03	SYSTEM AND METHOD FOR COPRODUCTING OXALIC ACID AND ACETIC ACID
EP3883578A4 (en)	2022-07-27	METHOD OF ADMINISTRATION OF CORTICOSTEROIDS
EP3522947C0 (en)	2025-02-19	TRANSCATHETERS FOR DELIVERING INTRACORPOREAL DEVICES
EP3490545A4 (en)	2020-07-22	METHOD FOR MEDICAL TREATMENT WITH SUR1-TRPM4 CHANNEL INHIBITORS
EP3558271A4 (en)	2020-07-22	METHOD FOR IMPROVING INFUSION REACTIONS
EP3262019C0 (en)	2024-07-31	PROCESS FOR DEHYDRATION OF OXYGEN-ENRICHED COMPOUNDS
EP3556392A4 (en)	2020-09-23	METHOD OF PROMOTING INSULIN SECRETION
EP3131957C0 (en)	2024-07-10	METHOD FOR IMPREGNATION OF POLYMER SUBSTRATES
EP3526205A4 (en)	2020-05-27	THERAPEUTIC CONNECTIONS AND METHOD FOR USE THEREOF
EP3373980A4 (en)	2019-06-12	METHOD FOR THE TREATMENT OF MUSCLE DYSTROPHIES
EP3454930A4 (en)	2020-01-08	ADVANCED LIQUID CRYSTAL FILM FOR COMBATING TRAVEL DISEASE AND METHOD FOR THIS
EP3271296C0 (en)	2024-12-11	SYSTEM AND METHOD FOR CAPACITIVE DEIONIZATION OF A LIQUID

Legal Events

Date	Code	Title	Description
2018-05-05	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2019-08-02	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2019-08-02	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2019-09-04	17P	Request for examination filed	Effective date: 20190404
2019-09-04	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2019-09-04	AX	Request for extension of the european patent	Extension state: BA ME
2020-02-05	DAV	Request for validation of the european patent (deleted)
2020-02-05	DAX	Request for extension of the european patent (deleted)
2020-06-03	A4	Supplementary search report drawn up and despatched	Effective date: 20200508
2020-06-03	RIC1	Information provided on ipc code assigned before grant	Ipc: A61P 29/00 20060101ALI20200501BHEP Ipc: A61K 31/485 20060101ALI20200501BHEP Ipc: A61K 31/4164 20060101ALI20200501BHEP Ipc: A61K 45/06 20060101ALI20200501BHEP Ipc: A61K 9/70 20060101AFI20200501BHEP Ipc: A61K 31/4174 20060101ALI20200501BHEP
2022-06-24	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: EXAMINATION IS IN PROGRESS
2022-07-27	17Q	First examination report despatched	Effective date: 20220624